Unit dose dry powder ejection carpule

United States Patent Application 20080281289

A simple, disposable device for a wounded individual to dispense a antibiotic or other medicine directly into their own open wound or treatment of a wound by a second party. The device dispenses a preloaded quantity of dry medication from an opening that is covered by a removable cap. Removal of the cap followed by pressing of a plunger dispenses the medication. The design of the carpule, barrel, of the device, the preloaded powder medicament, the flexible rod and rod head that pushes the dry powder into the wound and material selection appropriate to use in unfavorable environments are other features of the device.

Lewis, Michael I. (Bryn Mawr, PA, US)

11/800812

11/13/2008

05/08/2007

Click for automatic bibliography generation

604/403

206/572

A61B19/00; A61M3/00

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PATEL, PRITESH ASHOK

ADSERO IP LLC (LITTLETON, CO, US)

I claim:

1. —A unit dose dry powder ejection carpule comprising: a carpule having, a rod entrance orifice, an internal carpule shaft, external walls, an exit ejection orifice a piston internal head located at the rod entrance orifice end of the carpule, a rod extending from the piston internal head to a rod head near the exit ejection orifice, a preloaded charge of powder medicament, a barrier cap covering the exit ejection orifice, wherein the carpule, the piston internal head, the rod and the barrier cap are made of an—all polypropylene construction—that—can withstand vibration, cracking and misfire of the preloaded powdered medicament.

2. —A unit dose dry powder ejection carpule comprising: a carpule having, a rod entrance orifice, an internal carpule shaft, external walls, an exit ejection orifice a piston internal head located at the rod entrance orifice end of the carpule, a rod extending from the piston internal head to a rod head near the exit ejection orifice, a preloaded charge of powder medicament, a shovel head design around a periphery of the rod head nearest the walls of the exit ejection orifice, wherein an angle measured from an exit ejection orifice end of the internal carpule shaft and the surface of the shovel head design exceeds ninety degrees to—minimize dry powder particles from clogging on the shaft sidewalls and can withstand shock vibration, misfires—and—provides efficient non-traumatic delivery of the—preloaded—powder to a wound site, and consistent smooth ejection of the—preloaded powder—without clogging of the—preloaded powder—inside the—internal—carpule shaft.

3. —A unit dose dry powder ejection carpule comprising: a carpule having, a rod entrance orifice, an internal carpule shaft, external walls, an exit ejection orifice a piston internal head located at the rod entrance orifice end of the carpule, a rod extending from the piston internal head to a rod head near the exit ejection orifice, a preloaded charge of powder medicament, wherein the piston internal head is recessed within the rod entrance end of the internal carpule shaft for activation by—other surgical dental or medical generic sterile gun and trigger ejection systems—of the trigger-gun force system type providing—sterile surgical ejection—or the—medical disaster, ASAP, emergency ejection of the powder without the aid of a trigger-gun ejection system—by being—activated by simple pressure against the—piston—internal head.

4. —A unit dose dry powder ejection carpule comprising: a carpule having, a rod entrance orifice, an internal carpule shaft, external walls, an exit ejection orifice a piston internal head located at the rod entrance orifice end of the carpule, a rod extending from the piston internal head to a rod head near the exit ejection orifice, a preloaded charge of powder medicament, a barrier cap covering the exit ejection orifice, wherein the—barrier cap seals—the—exit—ejection—orifice and acts as—a—moisture-oxidation barrier and protects from premature ejection of the—preloaded—powder from the—exit ejection orifice—.

5. —A unit dose dry powder ejection carpule comprising: a carpule having, a rod entrance orifice, an internal carpule shaft, external walls, an exit ejection orifice a piston internal head located at the rod entrance orifice end of the carpule, a rod extending from the piston internal head to a rod head near the exit ejection orifice, a preloaded charge of powder medicament, a barrier cap covering the exit ejection orifice, wherein the—piston—internal—head—is recessed into the internal carpule shaft to protect—from premature ejection of the—preloaded—powder medicaments—because the—piston—internal—head can only be activated by a surgical gun or by depressing the—piston internal—head further into the—internal—carpule shaft by direct force on the—piston internal—head. This will eject the—preloaded—powder medicament in an ASAP emergency. —

6. —The unit dose dry powder ejection carpule of claim 1. further comprising: wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body.

7. —The unit dose dry powder ejection carpule of claim 2. further comprising: wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body.

8. —The unit dose dry powder ejection carpule of claim 3. further comprising: wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body.

9. —The unit dose dry powder ejection carpule of claim 4. further comprising: wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body.

10. —The unit dose dry powder ejection carpule of claim 5. further comprising: wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body.

11. —The unit dose dry powder ejection carpule of claim 1. further comprising: wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth.

12. —The unit dose dry powder ejection carpule of claim 2. further comprising: wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth.

13. —The unit dose dry powder ejection carpule of claim 3. further comprising: wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth.

14. —The unit dose dry powder ejection carpule of claim 4. further comprising: wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth.

15. —The unit dose dry powder ejection carpule of claim 5. further comprising: wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth.

16. —The unit dose dry powder ejection carpule of claim 1. further comprising: wherein—safe and non-raumatic, gentile ejection force on the rod head minimizes ejection discomfort pain from the deposit of the—preloaded—powder medicament into the wound.

17. —The unit dose dry powder ejection carpule of claim 2. further comprising: wherein—safe and non-traumatic, gentile ejection force on the rod head minimizes ejection discomfort pain from the deposit of the—preloaded—powder medicament into the wound.

18. —The unit dose dry powder ejection carpule of claim 3. further comprising: wherein—safe and non-traumatic, gentile ejection force on the rod head minimizes ejection discomfort pain from the deposit of the—preloaded—powder medicament into the wound.

19. —The unit dose dry powder ejection carpule of claim 4. further comprising: wherein—safe and non-traumatic, gentile ejection force on the rod head minimizes ejection discomfort pain from the deposit of the—preloaded—powder medicament into the wound.

20. —A unit dose dry powder ejection carpule of claim 1 further comprising: a shovel head design around a periphery of the rod head nearest the walls of the exit ejection orifice, wherein an angle measured from an exit ejection orifice end of the internal carpule shaft and the surface of the shovel head design exceeds ninety degrees to—minimize dry powder particles from clogging on the shaft sidewalls and can withstand shock vibration, misfires—and—provides efficient non-traumatic delivery of the—preloaded—powder to a wound site, and consistent smooth ejection of the—preloaded powder—without clogging of the—preloaded powder—inside the—internal—carpule shaft. wherein the piston internal head is recessed within the rod entrance end of the internal carpule shaft for activation by—other surgical dental or medical generic sterile gun and trigger ejection systems—of the trigger-gun force system type providing—sterile surgical ejection—or the—medical disaster, ASAP, emergency ejection of the powder without the aid of a trigger-gun ejection system—by being—activated by simple pressure against the—piston—internal head. wherein the—barrier cap seals—the—exit—ejection—orifice and acts as—a—moisture-oxidation barrier and protects from premature ejection of the—preloaded—powder from the—exit ejection orifice—. wherein the—piston—internal—head—is recessed into the internal carpule shaft to protect—from premature ejection of the—preloaded—powder medicaments—because the—piston—internal—head can only be activated by a surgical gun or by depressing the—piston internal—head further into the—internal—carpule shaft by direct force on the—piston internal—head. This will eject the—preloaded—powder medicament in an ASAP emergency. wherein—the unit dose dry powder ejection carpule can eject the—preloaded—powder medicament by simple force on the piston—internal—head for ASAP emergency application. This action will eject the—preloaded—powder medicament into the wound site for advancing the healing process and consistent ejection of antibiotic powders or other dry powder medicaments into wounds to aid in the prevention of a potential spread of infection to other tissues or other areas of the body. wherein—the deposit of dry powdered antibiotics into the periodontal pocket after scaling or surgery is completed on the moderate to advanced periodontitis patient. This deposit of antibiotic powder will potentate the reattachment of periodontal ligaments back to the root surface of the tooth. wherein—safe and non-traumatic, gentile ejection force on the rod head minimizes ejection discomfort pain from the deposit of the—preloaded—powder medicament into the wound.

BACKGROUND OF THE INVENTION

1. Field of the Invention

Unit dose medical and dental delivery systems have been used for many years in the—art of the—pharmaceutical industry. —Medicines, such as antibiotics, in dry powder form are more recently known in the art. —The present invention is a unit dose dry powder ejection carpule which will be referred to as “UDDPEC”. —

The present invention—is the first piston and rod head, unit dose, dry powder ejection carpule to be used for the ejection of a unit dose—of—dry powdered medicament from a carpule. The UDDPEC” device has a rod head—design—that facilitates consistent and sooth ejection delivery of the dry powder medicament to the tissue site. There is no federally sponsored research and development attached to the UDDPEC.

The technical invention field of endeavor pertains—to—:

A device for the safe and consistent non-traumatic deposit of dry powdered medicaments, —such as—antibiotics, into a tissue wound site. —The current invention so applied—is for emergency medical use in any disaster and additionally for use during medical surgical procedures. Dental use of—the current invention—includes ejection of dry powdered antibiotics into the periodontal pocket for the treatment of moderate to advanced periodontal disease.

2. Description of the Prior Art—

Medicines, such as antibiotics, in non-powder form, that are administered by traumatic means, are known in the art. It is considered that one of ordinary skill in the art is familiar with current devices from personal medical treatment—

SUMMARY OF THE INVENTION

This UDDPEC is designed for the localized ejection 2-10 milligrams of powdered medicaments at a desired tissue/wound site.

The present invention teaches over the prior art by a choice of materials that will withstand and fully function under less than desirable circumstances in an emergency.

The present invention further teaches over the prior art by being pre-loaded with powder. This is a huge advantage in the battlefield to enable self-administration of immediate antibiotics to assist an injured soldier. This could prevent cellulites, decrease in-patient hospital days, and possibly keep a person alive until the medics can start an (IV) intravenous antibiotic.

The present invention further teaches a novel rod head that has a designed convexity, and shovel head circumference.

The present invention is also compatible with other standard—devices—in the medical and dental industry, —such as, —generic sterile trigger and gun ejection systems. The UDDPEC will uniquely store and deliver a specified amount of dry medicament to the wound site to advance the healing phase, aid in the prevention of future infectious wound complications and in dentistry potentate the reconnection of periodontal ligaments back to the tooth surface.

The “UDDPEC” system is uniquely new and different because can eject the powder ASAP in an emergency setting, because of the medics new ability to now eject the powder by thumb pressure or pressure by a simple swiss army knife probe against the cylinder head into the shaft of the carpule. This action can all be done without the aid of a sterile surgical gun and trigger system by manually applying a gentle force to the trigger of a sterile gun and trigger delivery system will eject the preloaded sterile carpule powdered medicament into the desired sites for the purpose of wound healing.

The rod head design prevents binding of the powdered medicaments on the “UDDPEC” internal shaft sidewalls. This action provides consistent efficient gentle deposit of two to ten milligrams (2-10 mgs) of dry powdered medicaments to the wound tissue site.

This gentile depositing of the powder can eliminate further wound damage caused by the excessive force of other powder ejection systems when applied to the ASAP Emergency use.

This “UDDPEC” ability to uniquely eject the preloaded powder by two different methods insures consistent ejection when needed in different medical or dental situations:

• • a. Thumb force on the piston head in an [ASAP] emergency use. (ie. battlefield wound)
  • b. The UDDPEC easily fits into and adapts to other sterile generic trigger-gun ejectors resulting in the deposit of the unit dose dry powdered medicament as needed and necessary for wound healing.

BRIEF DESCRIPTION OF THE DRAWINGS

The above and other objects, features and additional advantages of the present invention will be more clearly understood from the following detailed description studied in conjunction with the accompanying drawing, in which:

Drawing 1 is a cut away cross section of a side view of the preferred embodiment of the instant invention.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT OF THE PRESENT INVENTION

—Drawing 1 shows that—The medicament is—in the form of—a preloaded powder (e) and is stored inside the—internal—carpule shaft—(f) —at the ejection exit orifice (a). The piston—internal—head (c) and attached—flexible—rod (c) is the only moving part. There is one removable part—that is the—sterile moisture barrier cap (h).

There is one non-moving part and that is the carpule and its internal shaft, —or bore—. The carpule assembly is readied for ejection by simple removal of the barrier cap (h). —The diameter and—circumferences—of the internal carpule shaft (f) —change from the piston internal head—(c) —to the exit—ejection-orifice (a). See Drawing 1 for—the—diameters.

The—internal carpule shaft (f) has a—25 degree—rod-shaft curve—(i), —that—aids and provides ease of preloaded powder (e) placement. Total length—of the carpule shaft external walls—is 0.45-1.5 inches. All parts are—manufactured from—polymers of plastic and are disposable as medical biological waste.

The polypropylene—material of the carpule—will withstand and fully function under less than desirable circumstances in an emergency.

—The—rod head (g) has a designed convexity (I), and shovel head circumference (m), —This design—insures efficient non-traumatic delivery of the preloaded powder (e) dosage to the wound site (not shown). This design of the rod head (g) aids to minimize powder particles from clogging on the—internal carpule—shaft (f) sidewalls. The shovel design of the rod head (g) acts by scraping the—preloaded—powder (e) from the sides of the—internal carpule shaft (f) —walls as the—flexible—rod (d) is moving forward towards the exit—ejection—orifice (a).

The UDDPEC works—in the following manner. —

The preloaded powder (e) is packed inside the internal carpule ejection shaft (f). The rod head—(g) —is positioned directly behind the preloaded powder (e) to be ejected from the—internal carpule-shaft (f). The—piston—internal head (c) and—flexible rod—(d) extends into the—internal carpule shaft—(f) —enters the—internal carpule—shaft—(f)—from (3-10 mm) outside of the—rod—entrance orifice (j) and moves inside the internal carpule shaft (f). The 3-10 mm entrance distance depends upon the dosage of the—preloaded—powder—(e) to be delivered to the patient (not shown).

—Between—two—and—ten milligrams (2-10 mgs) of a—preloaded—dry powder (e) is preloaded inside the—internal carpule—shaft (f) at the exit—ejection—orifice (a) by a sterile FDA approved machine—(not shown).

—A—trigger force (not shown) against the piston—internal—head (c) will move the—flexible—rod (d) inside the—internal—carpule shaft (f) pushing the—preloaded—powder—(e) —forward inside the—internal carpule shaft (f) —towards the exit—ejection—orifice (a), resulting with the ejection of the preloaded powder—(e) out from the exit—ejection—orifice (a).

The total forward movement of the—piston internal—head (c) stops exactly at the

exit ejection orifice (a). The result of this forward movement is ejection of the desired preloaded powder (e) out of the 1.3 mm round exit ejection orifice (a). The piston—internal—head (c) and—flexible—rod pushes the—preloaded powder (e)2-10 mm forward inside the—internal carpule—shaft (f).

The final result of—the—flexible—rod (d) forward movement inside the—internal carpule—shaft (f) is ejection of the—preloaded powder—(e) through the—internal carpule—shaft (f) exit—ejection—orifice (a).

—The current invention—is designed to work with other generic gun and trigger systems—that are standards—in the industry—and have—similar carpule diameters and circumferences.