Matches 1 - 50 out of 72 1 2 >


Match Document Document Title Score
WO/2010/033757A1 NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disordersuch as learning,...
1000
US20160122359 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
EP2542254A4 SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
JP2016185948A COMPOUNDS STABILIZING NMDA RECEPTOR MODULATORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME  
PROBLEM TO BE SOLVED: To provide compounds having enhanced potency in modulation of N-methyl-D-aspartate (NMDA) receptor activity, the compounds being contemplated for use in treatment of diseases...
0
JP5928828B2 Secondary structure of stabilizing a NMDA receptor modulator, and its use  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
US20180185299 THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA  
The present invention relates to use of biphenols in the preparation of a medicament for the prevention and treatment of ischemic stroke, specifically to use of...
0
US20150051262 NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,...
0
US20140107037 METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, OR OTHER DISORDERS  
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine...
0
EP2771021A4 NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,...
0
JP6328169B2 The medicine constituent containing the compound and it which stabilize a NMDA receptor modulator  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
JP6035326B2 How to treat the disease of Alzheimer's disease, a Huntington's disease, autism, and others  
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine...
0
EP2542254A1 SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
EP3514158A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2017/201285A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2013/063120A3 NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,...
0
WO/2012/149389A3 METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, OR OTHER DISORDERS  
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine...
0
JP2013519683A Secondary structure of stabilizing a NMDA receptor modulator, and its use  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
JP2014520072A How to treat the disease of Alzheimer's disease, a Huntington's disease, autism, and others  
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine...
0
EP3679931A3 METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, AND OTHER DISORDERS  
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine...
0
WO/2014/120786A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2019/152678A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be useful in the treatment of conditions such as depression and related disorders as well as...
0
WO/2014/120784A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2014/120800A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2014/120783A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2014/120789A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
WO/2019/152685A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND METHODS OF USING SAME  
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as...
0
6025471 Diazaspiro, azepino and azabicyclo therapeutic peptides  
The present invention relates a number of novel peptide sequences which include a spirolactam, bicyclic or tricyclic peptidomimetic unit. The peptides disclosed herein exhibit binding to cardiac...
0
WO/2013/063120A2 NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,...
0
WO/2017/201283A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders....
0
WO/2019/152696A1 SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF  
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as...
0
5166136 Spirolactam containing peptides  
These are described spirolactam derivatives of formulae (Ia) and (Ib) ##STR1## wherein R represents a hydrogen atom or a conventional nitrogen protecting group; R1 represents a hydrogen atom or a...
0
6541453 Peptide derivatives  
Novel peptide derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing then are useful in treating MHC class II dependent T-cell method autoimmune or...
0
8951968 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
8492340 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
WO/2017/093354A1 NMDAR ANTAGONISTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS  
The present invention relates to an N-Methyl-D-aspartate (NMDA) receptor antagonist, for use in the treatment of diseases associated with angiogenesis such as tumor angiogenesis, ocular...
0
9796755 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
9512133 NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning,...
0
9101612 Secondary structure stabilized NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
8673843 NMDA receptors modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,...
0
9198948 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
10167314 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
9149501 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
9593145 Secondary structure stabilized NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,...
0
9340576 Methods of treating depression and other related diseases  
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
0
9925169 Spiro-lactam NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
10273239 Spiro-lactam NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
10253032 Spiro-lactam NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
9828384 Spiro-lactam NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0
9802946 NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning,...
0
9512134 Spiro-lactam NMDA receptor modulators and uses thereof  
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related...
0


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