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WO/2010/033757A1 |
NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disordersuch as learning,... |
1000 |
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US20160122359 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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EP2542254A4 |
SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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JP2016185948A |
COMPOUNDS STABILIZING NMDA RECEPTOR MODULATORS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
PROBLEM TO BE SOLVED: To provide compounds having enhanced potency in modulation of N-methyl-D-aspartate (NMDA) receptor activity, the compounds being contemplated for use in treatment of diseases... |
0 |
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JP5928828B2 |
Secondary structure of stabilizing a NMDA receptor modulator, and its use
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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US20180185299 |
THE USE OF DIPHENOL IN PREPARATION OF MEDICINES FOR PREVENTION AND TREATMENT OF CEREBRAL ISCHEMIA
The present invention relates to use of biphenols in the preparation of a medicament for the prevention and treatment of ischemic stroke, specifically to use of... |
0 |
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US20150051262 |
NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,... |
0 |
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US20140107037 |
METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, OR OTHER DISORDERS
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine... |
0 |
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EP2771021A4 |
NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,... |
0 |
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JP6328169B2 |
The medicine constituent containing the compound and it which stabilize a NMDA receptor modulator
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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JP6035326B2 |
How to treat the disease of Alzheimer's disease, a Huntington's disease, autism, and others
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine... |
0 |
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EP2542254A1 |
SECONDARY STRUCTURE STABILIZED NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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EP3514158A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2017/201285A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2013/063120A3 |
NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,... |
0 |
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WO/2012/149389A3 |
METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, OR OTHER DISORDERS
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine... |
0 |
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JP2013519683A |
Secondary structure of stabilizing a NMDA receptor modulator, and its use
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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JP2014520072A |
How to treat the disease of Alzheimer's disease, a Huntington's disease, autism, and others
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine... |
0 |
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EP3679931A3 |
METHODS OF TREATING ALZHEIMER'S DISEASE, HUNTINGTON'S DISEASE, AUTISM, AND OTHER DISORDERS
The disclosure relates, at least in part, to methods of treating autism in a patient in need thereof by administering an effective amount of a disclosed compound, e.g., a NMDA receptor glycine... |
0 |
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WO/2014/120786A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2019/152678A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be useful in the treatment of conditions such as depression and related disorders as well as... |
0 |
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WO/2014/120784A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2014/120800A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2014/120783A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2014/120789A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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WO/2019/152685A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND METHODS OF USING SAME
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as... |
0 |
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6025471 |
Diazaspiro, azepino and azabicyclo therapeutic peptides
The present invention relates a number of novel peptide sequences which include a spirolactam, bicyclic or tricyclic peptidomimetic unit. The peptides disclosed herein exhibit binding to cardiac... |
0 |
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WO/2013/063120A2 |
NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,... |
0 |
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WO/2017/201283A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders.... |
0 |
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WO/2019/152696A1 |
SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF
Disclosed are compounds having potency in the modulation of NMDA receptor activity. Such compounds can be used in the treatment of conditions such as depression and related disorders as well as... |
0 |
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5166136 |
Spirolactam containing peptides
These are described spirolactam derivatives of formulae (Ia) and (Ib) ##STR1## wherein R represents a hydrogen atom or a conventional nitrogen protecting group; R1 represents a hydrogen atom or a... |
0 |
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6541453 |
Peptide derivatives
Novel peptide derivatives, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing then are useful in treating MHC class II dependent T-cell method autoimmune or... |
0 |
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8951968 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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8492340 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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WO/2017/093354A1 |
NMDAR ANTAGONISTS FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ANGIOGENESIS
The present invention relates to an N-Methyl-D-aspartate (NMDA) receptor antagonist, for use in the treatment of diseases associated with angiogenesis such as tumor angiogenesis, ocular... |
0 |
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9796755 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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9512133 |
NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning,... |
0 |
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9101612 |
Secondary structure stabilized NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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8673843 |
NMDA receptors modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders, such as learning,... |
0 |
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9198948 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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10167314 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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9149501 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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9593145 |
Secondary structure stabilized NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorders such as learning,... |
0 |
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9340576 |
Methods of treating depression and other related diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist. |
0 |
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9925169 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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10273239 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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10253032 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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9828384 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMD A receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |
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9802946 |
NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of diseases and disorder such as learning,... |
0 |
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9512134 |
Spiro-lactam NMDA receptor modulators and uses thereof
Disclosed are compounds having enhanced potency in the modulation of NMDA receptor activity. Such compounds are contemplated for use in the treatment of conditions such as depression and related... |
0 |