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Document Title |
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WO/2011/139275A1 |
METHOD OF DETECTING NERVE AGENTS USING NOVEL ASSAY AGENTS
The teachings provided herein are directed to compounds and methods for detecting nerve agents using rhodamine-dehved detection compounds. A rhodamine-derived detection compound for nerve agents... |
1000 |
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EP3446688A1 |
USE OF ANTI-CONNEXIN AGENTS FOR ENHANCING THE THERAPEUTIC EFFECT OF ACETYLCHOLINESTERASE INHIBITORS
This invention relates to improvements in therapeutic neurological and neuropsychic treatments using acetylcholinesterase inhibitors. More specifically, the invention enables the effects of the... |
936 |
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US20110275161 |
METHOD OF DETECTING NERVE AGENTS USING NOVEL ASSAY AGENTS
The teachings provided herein are directed to compounds and methods for detecting nerve agents using rhodamine-derived detection compounds. A rhodamine-derived detection compound for nerve agents... |
884 |
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US20200163952 |
COMPOSITIONS AND METHODS FOR TREATING NERVE AGENT EXPOSURE
The present disclosure is directed to transdermal compositions comprising a poison antidote, and methods of using such compositions to counteract the effects of a poison. |
787 |
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US20090176802 |
ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS
A novel method for treating a mammal exposed to an exogenous neurotoxic agent is disclosed. |
728 |
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WO/2007/092458A1 |
ANTIDOTES TO EXOGENOUS NEUROTOXIC AGENTS
The present application discloses the use of compounds exhibiting both acetylcholinesterase (AchE) inhibition properties and σ-1 receptor agonist capacities for treating a mammal exposed to an... |
724 |
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WO/2020/112766A1 |
COMPOSITIONS AND METHODS FOR TREATING NERVE AGENT EXPOSURE
The present disclosure is directed to transdermal compositions comprising a poison antidote, and methods of using such compositions to counteract the effects of a poison. |
707 |
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US20120153156 |
Remote optothermal sensor (rose) standoff detection of CWAs, explosives vapors and TICs
A system and method for standoff detection of explosives, CWAs and TICs using optical techniques. Preliminary analysis indicates detection of TNT at a distance of 0.5 km with a signal-to-noise... |
704 |
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DE202021104545U1 |
Test kit for the detection of acetylcholinesterase inhibitors
Test kit for detecting organophosphate compounds, comprising a carrier device (2) with a top (18) and a bottom (19), a sampling device (6), a buffer solution (7) in a sample tube (32) with a lid... |
697 |
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WO/2010/025259A1 |
METHOD OF TREATING ORGANOPHOSPHOROUS POISONING
The present invention is directed to various methods for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus... |
694 |
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9255091 |
Benzothiazole-based pyridinium compounds
The compositions of the invention are novel benzothiazol-based pyridinium compounds with potent acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. Such... |
684 |
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US20150259336 |
Benzothiazole-based Pyridinium Compounds for the Treatment of Neurodegenerative Diseases or Nerve Agent Exposure
The compositions of the invention are novel benzothiazol-based pyridinium compounds with potent acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activities. Such... |
684 |
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WO/2013/132490A1 |
COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS
The invention provides a method of treating benzodiazepine-resistant status epilepticus in a subject having been exposed to a nerve agent inducing the status epilepticus. |
654 |
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US20090023706 |
Method of Treating Organophosphorous Poisoning
The present invention is directed to various methods for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus... |
653 |
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EP2334182A1 |
METHOD OF TREATING ORGANOPHOSPHOROUS POISONING
The present invention is directed to various methods for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus... |
653 |
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WO/2023/004152A2 |
COMPOSITIONS, METHODS, AND ARTICLES COMPRISING COCAINE ESTERASE FOR DETOXIFYING AN ORGANOPHOSPHATE-BASED AGENT
Disclosed herein are compositions, methods, and articles of personal protective equipment for use in detoxifying an organophosphate-based agent, wherein the compositions, methods, and articles... |
642 |
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US20230066416 |
Test kit for detecting acetylcholinesterase inhibitors
A test kit for detecting organophosphate compounds, includes a support apparatus, a sampling device, a buffer solution in a sample tube, and an acetylcholinesterase as the first active component... |
640 |
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EP4141125A1 |
ASSAY KIT FOR DETECTING ACETYLCHOLINESTERASE INHIBITORS
The invention relates to a test kit for detecting organophosphate compounds, comprising a carrier device (2), a sampling device (6), a buffer solution (7) in a sample tube (32), and an... |
640 |
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US20150038588 |
COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS
The invention provides a method of treating benzodiazepine-resistant status epilepticus in a subject having been exposed to a nerve agent inducing the status epilepticus. |
631 |
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9623404 |
Metal organic frameworks for the catalytic detoxification of chemical warfare nerve agents
A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the... |
623 |
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US20160175827 |
METAL ORGANIC FRAMEWORKS FOR THE CATALYTIC DETOXIFICATION OF CHEMICAL WARFARE NERVE AGENTS
A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the... |
623 |
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WO/2021/258150A1 |
METHODS OF TREATING OR PREVENTING ORGANOPHOSPHORUS POISONING
The present invention relates generally to methods of treating or preventing organophosphorus poisoning. In particular, the present invention is directed to use of intranasal formulations... |
617 |
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10272279 |
Metal organic frameworks for the catalytic detoxification of chemical warfare nerve agents
A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the... |
613 |
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10167498 |
Gradient elution moving boundary electrophoresis for use with complex samples and detection of toxins
Methods of detecting the presence of toxins in a sample using electrophoretic separations and of performing electrophoretic separation of complex samples are provided. The method of detecting the... |
602 |
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EP2586436A1 |
Use of anti-connexin agents for enhancing the therapeutic effect of acetylcholinesterase inhibitor
This invention relates to improvements in therapeutic neurological and neuropsychic treatments using acetylcholinesterase inhibitors. More specifically, the invention enables the effects of the... |
599 |
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EP2822655A1 |
COMPOSITIONS AND METHODS OF TREATMENT OF STATUS EPILEPTICUS
The invention provides a method of treating benzodiazepine-resistant status epilepticus in a subject having been exposed to a nerve agent inducing the status epilepticus. |
595 |
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9354231 |
Reactive self-indicating absorbent materials, methods, and systems
The present disclosure relates, according to some embodiments, reactive self-indicating adsorbent materials, methods, and systems. A system may comprise, for example, a reactive self indicating... |
546 |
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US20170128761 |
METAL ORGANIC FRAMEWORKS FOR THE CATALYTIC DETOXIFICATION OF CHEMICAL WARFARE NERVE AGENTS
A method of using a metal organic framework (MOF) comprising a metal ion and an at least bidendate organic ligand to catalytically detoxify chemical warfare nerve agents including exposing the... |
535 |
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WO/2020/227413A1 |
DEVICE FOR DETECTING ORGANOPHOSPHATES
This invention relates to a device that can be used is used to detect organophosphates and carbamate on surfaces including food, clothing (including as wearable pesticide detectors) and machinery. |
529 |
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US20230172895 |
METHODS OF TREATING OR PREVENTING ORGANOPHOSPHORUS POISONING
The present invention relates generally to methods of treating or preventing organophosphorus poisoning. In particular, the present invention is directed to use of intranasal formulations... |
525 |
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US20230270750 |
CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS
Compounds are used in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of intoxication with at least one organophosphorus nerve agent.... |
486 |
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US20160031854 |
ACTIVATION OR REACTIVATION OF ACHE
Disclosed herein is an in vitro or in vivo method of activating or reversing inactivation of acetylcholinesterase (AChE) or butyrylcholinesterase (BuchE) using compounds of the present disclosure.... |
477 |
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10371607 |
Tamper-resistant chemical sampling
Methods, systems, and apparatuses are disclosed for a tamper-resistant collection and retention a chemical sample. In one embodiment, the tamper-resistant system comprises a container operable to... |
474 |
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US20170131186 |
TAMPER-RESISTANT CHEMICAL SAMPLING
Methods, systems, and apparatuses are disclosed for a tamper-resistant collection and retention a chemical sample. In one embodiment, the tamper-resistant system comprises a container operable to... |
474 |
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US20220062906 |
DEVICE FOR DETECTING ORGANOPHOSPHATES
This invention relates to a device that can be used is used to detect organophosphates and carbamate on surfaces including food, clothing (including as wearable pesticide detectors) and machinery. |
469 |
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EP3945092A1 |
CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS
The present invention relates to compounds for their use in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of the intoxication with at least... |
463 |
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JP2023541345A |
Carbaldehyde oxime as a butyrylcholinesterase reactivator
The present invention relates to compounds for use in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of poisoning by at least one... |
450 |
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WO/2015/200485A1 |
TAMPER-RESISTANT CHEMICAL VAPOUR SAMPLING
Methods, systems, and apparatuses are disclosed for a tamper-resistant collection and retention a chemical sample. In one embodiment, the tamper-resistant system comprises a container operable to... |
431 |
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WO/2012/123936A2 |
DEVICES AND METHODS FOR REAL TIME DETECTION OF CHEMICAL AND BIOLOGICAL GASEOUS HAZARDS
Systems, methods and devices are provided for real-time monitoring of a chemical or pathogen presence and/or level in a gaseous environment. The system comprises at least one fixed or portable... |
431 |
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EP3224269A1 |
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
Described herein are neuroactive steroids of the Formula (II):or a pharmaceutically acceptable salt thereof; wherein A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6and------are as defined herein. Such... |
429 |
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WO/2016/082789A1 |
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
Described herein are neuroactive steroids of the Formula (II) : or a pharmaceutically acceptable salt thereof; wherein A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6 and ----- are as defined herein.... |
429 |
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JP2017535586A |
Compositions and Methods for Treating CNS Disorders
Equation (II):Neurostimulatory steroid or pharmaceutically acceptable salt thereof in formula (II): A, R1, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6andAre described herein as neurostimulant steroids or... |
393 |
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EP3826670A1 |
METHODS AND COMPOSITIONS FOR TREATING CHRONIC EFFECTS OF RADIATION AND CHEMICAL EXPOSURE
A method of treating a chronic effect of radiation or chemical exposure comprises administering to a subject a composition comprising an anti-AGE antibody. A composition for treating a chronic... |
374 |
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WO/2020/023532A1 |
METHODS AND COMPOSITIONS FOR TREATING CHRONIC EFFECTS OF RADIATION AND CHEMICAL EXPOSURE
A method of treating a chronic effect of radiation or chemical exposure comprises administering to a subject a composition comprising an anti-AGE antibody. A composition for treating a chronic... |
354 |
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WO/2022/023315A1 |
CARBALDEHYDE OXIMES AS BUTYRYLCHOLINESTERASE REACTIVATORS
The present invention relates to compounds for their use in the reactivation of butyrylcholinesterase. Such compounds are useful in the treatment or prevention of the intoxication with at least... |
350 |
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9132135 |
Method of treating organophosphorous poisoning
The present invention is directed to various methods for treating organophosphorus poisoning in an animal that is at risk of exposure to an organophosphorus compound or preventing organophosphorus... |
342 |
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WO/2021/189112A1 |
METHOD OF DETECTION
A method for detection of a nerve agent in a sample, which method comprises (a) irradiating an optical sensing element, the optical sensing element comprising a fluorescent sensing compound... |
298 |
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US20160377617 |
DETECTION OF THE DEGREE OF EXPOSURE TO CHEMICAL WARFARE NERVE AGENTS AND ORGANOPHOSPHATE PESTICIDES WITH LATERAL FLOW ASSAYS
A sample analysis device used to detect a level of exposure of organophosphorus within a sample comprising a sample collection pad, at least one conjugate zone comprising an anti-analyte antibody... |
274 |
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10288614 |
Detection of the degree of exposure to chemical warfare nerve agents and organophosphate pesticides with lateral flow assays
A sample analysis device used to detect a level of exposure of organophosphorus within a sample comprising a sample collection pad, at least one conjugate zone comprising an anti-analyte antibody... |
274 |
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WO/2023/081873A1 |
MATERIALS AND METHODS FOR PREVENTING OR REDUCING TOXICITY TO ORGANOPHOSPHATES AND OTHER TOXIC MATERIALS
The present invention provides materials and methods for alleviating organophosphate toxicity. More specifically, the invention provides pharmaceutical compositions comprising a protein, and/or... |
274 |