Match Document Document Title Score
US20080213352 Liposome carriers for in vivo delivery of fullerenes  
Described herein are pharmaceutically acceptable compositions comprising fullerene molecules dispersed in vesicles comprising phosphatidylcholine (PC) phospholipid molecules and non-PC...
1000
8263117 C70-containing liposome, method for producing the same, and use of the same  
A solution containing a C70 cyclodextrin complex and a solution containing a lipid that is capable of forming a liposome are mixed together at a temperature in a range of 10° C. to 45° C. This...
990
US20110059024 LIPOSOME COMPOSITION, AND DIAGNOSTIC CONTRAST AGENT, THERAPEUTIC ENHANCER, AND PHARMACEUTICAL COMPOSITION USING THE SAME  
To provide a liposome composition, which contains at least one liposome, gas entrapped in the liposome, and at least one fullerene encapsulated in or adsorbed on the liposome.
918
US20100278885 C70-Containing Liposome, Method for Producing the Same, and Use of the Same  
A solution containing a C70 cyclodextrin complex and a solution containing a lipid that is capable of forming a liposome are mixed together at a temperature in a range of 10° C. to 45° C. This...
868
10418539 Enhanced superconductivity of fullerenes  
Superconductive fullerenes, methods for enhancing characteristics of superconductive fullerenes and devices incorporating the fullerenes are disclosed. Enhancements can include increase in the...
764
9685600 Enhanced superconductivity of fullerenes  
Methods for enhancing characteristics of superconductive fullerenes and devices incorporating the fullerenes are disclosed. Enhancements can include increase in the critical transition temperature...
753
8241648 Amphiphilic or lipophilic polar functionalized fullerenes and their uses  
Described herein are synthetically modified fullerene molecules, wherein the fullerene is preferably ellipsoid in shape with an equatorial band and two opposing poles, comprising an adduct at one...
752
US20120034162 Fullerene Assisted Cell Penetrating Peptides  
A composition and method is described for intracellular delivery of fullerene containing peptides. The composition and method involve fullerene-substituted phenylalanine as part of a peptide based...
751
6355225 Fullerene contrast agent for magnetic resonance imaging and spectroscopy  
A non-toxic contrast agent for enhancing contrast in in vivo magnetic resonance measurements, comprised of a water-soluble, stable paramagnetic fullerene that is free of paramagnetic metal...
688
7507764 Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes  
Herein are disclosed substituted fullerenes, comprising a fullerene core (Cn), wherein n is an even integer greater than or equal to 60; 3 or 5 dihydrocarbylmalonate (>C(COOR1)(COOR2)) groups...
683
US20110021630 METHOD FOR TREATING WOUNDS BY ADMINISTERING FULLERENES  
Disclosed herein are methods for treating wounds. In one embodiment, the method comprises: administering to a subject in need thereof a therapeutically effective amount of a synthetically modified...
675
7947262 Use of fullerenes for the treatment of mast cell and basophil-mediated disease  
Mast cell (MC) and peripheral blood basophil (PBB)-associated diseases are treated or prevented, or their symptoms are alleviated by the administration of water soluble fullerenes (buckeyballs) to...
673
US20080213324 Amphiphilic or lipophilic polar functionalized fullerenes and their uses  
Described herein are synthetically modified fullerene molecules, wherein the fullerene is preferably ellipsoid in shape with an equatorial band and two opposing poles, comprising an adduct at one...
666
9233164 Water soluble fullerene formulations and methods of use thereof  
The present invention provides water soluble fullerene formulations and methods of use thereof.
661
US20050143327 Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes  
Herein are disclosed substituted fullerenes, comprising a fullerene core (Cn), wherein n is an even integer greater than or equal to 60; 3 or 5 dihydrocarbylmalonate (>C(COOR1)(COOR2)) groups...
658
US20110028522 FULLERENE THERAPIES FOR INFLAMMATION  
Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified...
654
US20080214514 Steroid derivatives of fullerenes  
Described herein are steroid derivatives of fullerene moieties, for example fullerene derivatives in which cholesterol, or a cholesterol moiety, is attached via ester, amide, or ether bonds to one...
646
US20130323188 Water Soluble Fullerene Formulations and Methods of Use Thereof  
The present invention provides water soluble fullerene formulations and methods of use thereof.
637
US20190038668 USE OF FULLERENE STRUCTURE IN PREPARATION OF MEDICAMENTS FOR TREATING PARKINSON'S DISEASE  
An application of a fullerene structure in the preparation of medications for treating Parkinson's disease. The fullerene structure comprises at least one of the following active ingredient...
631
US20110009486 METHOD FOR TREATING PRURITUS BY ADMINISTERING FULLERENES  
Disclosed herein are methods of treating pruritus in a subject in need thereof. A method of treating pruritus comprises administering a therapeutically effective amount of fullerenes to a subject...
631
US20030027870 Fullerene derivatives that modulate nitric oxide synthase and clamodulin activity  
This invention provides novel fullerene derivatives, particularly fullerene derivatives that are water-soluble, that modulate the activity of nitric oxide synthase (NOS) and/or calmodulin. The...
628
7825161 Higher fullerenes useful as radical scavengers  
Chemically functionalized fullerenes are useful in various applications as radical scavengers. These chemically functionalized fullerenes offer the advantages of preservation of the high innate...
627
US20080107618 USE OF FULLERENES FOR THE TREATMENT OF MAST CELL AND BASOPHIL-MEDIATED DISEASE  
Mast cell (MC) and peripheral blood basophil (PBB)-associated diseases are treated or prevented, or their symptoms are alleviated by the administration of water soluble fullerenes (buckeyballs) to...
623
US20050245606 High-efficiency fullerene-based radical scavengers  
Chemically functionalized fullerenes are useful in various applications as radical scavengers. These chemically functionalized fullerenes offer the advantages of preservation of the high innate...
622
US20040166152 Use of buckysome or carbon nanotube for drug delivery  
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the...
619
5688486 Use of fullerenes in diagnostic and/or therapeutic agents  
Compounds including tight molecular meshes, preferably curved in one or two directions, such as fullerenes and met-cars, can be used as carriers for diagnostic or therapeutic agents, especially...
616
US20110003773 USING FULLERENES TO ENHANCE AND STIMULATE HAIR GROWTH  
Described herein are methods for treating lack of hair growth or a reduction or loss of existing hair by stimulating and/or restoring hair growth, or preventing hair loss. The methods comprise...
611
US20140140985 FULLERENE AND ITS USE TO MAINTAIN GOOD HEALTH AND TO PROLONG THE EXPECTED LIFESPAN OF MAMMALS  
A water-insoluble fullerene is at least partially dissolved in a biocompatible lipid carrier, especially a fat or an oil such as butter, olive oil, and liquid paraffin. When administered to...
604
US20070048870 Endohedral fullerenes as spin labels and MRI contrast agents  
This invention pertains to the discovery that certain endohedral fullerenes are functional paramagnetic materials exhibiting increased relaxation times. These endohedral fullerenes provide...
603
US20110190251 METHOD FOR INHIBITING THE BUILD-UP OF ARTERIAL PLAQUE BY ADMINISTERING FULLERENES  
Disclosed herein are methods of inhibiting the build-up of arterial plaque in a subject in need thereof. These methods comprise administering to the subject in need thereof a therapeutically...
603
US20050239717 Higher fullerenes useful as radical scavengers  
Chemically functionalized fullerenes are useful in various applications as radical scavengers. These chemically functionalized fullerenes offer the advantages of preservation of the high innate...
603
US20180271906 FULLERENE AND ITS USE TO MAINTAIN GOOD HEALTH AND TO PROLONG THE EXPECTED LIFESPAN OF MAMMALS  
A water-insoluble fullerene is at least partially dissolved in a biocompatible lipid carrier, especially a fat or an oil such as butter, olive oil, and liquid paraffin. When administered to...
598
US20110251158 FULLERENE THERAPIES FOR INFLAMMATION AND INHIBITION OF BUILD-UP OF ARTERIAL PLAQUE  
Described herein are methods for treating inflammatory disorders or for inhibiting the build-up of arterial plaque. The methods comprise administering to a subject in need thereof a...
584
US20070025918 Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization  
The invention relates to carbon-13 enriched fullerene and carbon nanotube (CNT) compositions for improved magnetic resonance imaging (“MRI”). The invention also relates to a dynamic nuclear...
577
7758889 Fullerenes in targeted therapies  
Herein we disclose a composition, comprising a Cn-Ab, wherein Cn is a fullerene or nanotube comprising n carbon atoms, and Ab is a moiety comprising an antigen-binding site and is linked to the...
564
US20160331698 FULLERENE COMPOUNDS AS ANTIOXIDANT THERAPY  
Disclosed herein are small-gap fullerene compositions and methods of using for therapeutic or cosmetic purposes. Specifically exemplified is the use of derivatized SGFs so as to be water-soluble....
563
US20030036562 Water-soluble dendrimeric fullerene as anti-HIV therapeutic  
A composition comprising: (a) a pharmaceutically effective amount of water-soluble fullerene compounds of one or more of the formulae I-VI: 1 where L is a linker of the formula 2 X is NH or O, R...
555
7070810 Use of buckysome or carbon nanotube for drug delivery  
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the...
546
10342797 Solubility of therapeutic agents  
Disclosed herein are methods and compositions to improve the solubility of therapeutic agents. In one embodiment, a method of improving solubility of a therapeutic agent includes mixing fullerene...
521
6397102 Device and method for photoactivated drug therapy  
A device and method are presented wherein a common drug for a particular treatment is given to the patient in an inactive form. The drug can be administered systemically or topically. The activity...
518
8680125 Fullerene therapies for inflammation  
Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified...
505
US20080095834 Mitochondriotropic Phospholipid Vesicles  
Mitochondriotropic phospholipid vesicles, i.e., mitochondriotropic liposomes, that comprise a hydrophobized amphiphilic delocalized cation, such as those comprising, e.g., a triphenylphosphonium...
491
US20110130580 USE OF BUCKYSOME OR CARBON NANOTUBE FOR DRUG DELIVERY  
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the...
482
10780116 Use of fullerene structure in preparation of medicaments for treating Parkinson's disease  
An application of a fullerene structure in the preparation of medications for treating Parkinson's disease. The fullerene structure comprises at least one of the following active ingredient...
482
US20060127470 Use of buckysome or carbon nanotube for drug delivery  
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the...
479
US20030180491 Use of buckysome or carbon nanotube for drug delivery  
Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the...
477
US20140161733 BIOMARKER-TARGETING CONTRAST AGENTS AND THEIR USE IN MAGNETIC RESONANCE IMAGING FOR DETECTION OF ATHEROSCLEROTIC PLAQUE  
A composition comprising: a liposome having a bilayer structure, a gadofullerene having a high relaxivity, and an amphiphilic receptor ligand. In the composition, the gadofullerene is embedded in...
458
9944583 Methods for ameliorating and preventing central nervous system inflammation  
The invention provides compositions and methods for ameliorating, treating, reversing or preventing pathology or inflammation in the central nervous system (CNS), or the brain, caused or mediated...
447
8563585 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Fullerene therapies for inflammation
 
Described herein are methods for treating inflammatory disorders. The methods comprise administering to a subject in need thereof a therapeutically effective amount of a synthetically modified...
447
10293054 Lipofullerene-saccharide conjugates and their use as antimetastatic agents for the inhibition of mammalian neoplasms  
In some embodiments, a lipofullerene-saccharide compound and a method of inhibiting and/or ameliorating metastasis of neoplastic cells using said compound is disclosed herein. The...
444


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