Matches 1 - 40 out of 40


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DE102018116353B4 Method for the detection and enumeration of epigenetic immune cells in human blood samples for immunodiagnostics and newborn screening  
A method for an improved methylation assay for identifying blood immune cells, comprising the steps of a) providing a sample of human blood, in particular from a newborn, comprising genomic DNA...
DE102018112644B4 CXCR3 as an epigenetic marker for the identification of inflammatory immune cells, in particular CD8 + memory T cells  
A method for specifically identifying the CXC motif chemokine receptor 3 (CXCR3) subpopulation of immune cells in a mammalian sample comprising immune cells, comprising analyzing the methylation...
DE102018116353A1 Method for the detection and enumeration of epigenetic immune cells in human blood samples for immunodiagnostics and newborn screening  
The present invention relates to improved methods for the detection and enumeration of epigenetic blood and immune cells, and corresponding applications and kits.
DE102019005689A1 COMPOSITIONS AND METHOD FOR DETECTING THE NUCLEIC ACID OF GROUP-B-STREPTOCOCCUS  
Disclosed are nucleic acid oligomers, including amplification oligomers and detection probes, for detecting the nucleic acid of Group B Streptococcus (GBS; Streptococcus agalactiae). Methods for...
DE102018112644A1 CXCR3 as an epigenetic marker for the identification of inflammatory immune cells, in particular CD8 + Gedächnis T cells  
The present invention relates to a method, in particular an in vitro method, for the specific identification of the CXC motif chemokine receptor 3 (CXCR3) subpopulation of immune cells in a sample...
DE102017126248B4 ERGIC1 as epigenetic marker for the identification of immune cells, in particular monocytic myeloid-derived suppressor cells (mMDSCs)  
A method of identifying monoclonal myeloid-derived suppressor cells (mMDSCs) in a mammalian sample comprising analyzing a modification, preferably the methylation status, of at least one CpG...
DE102017125335B4 Amplicon region as an epigenetic marker for the identification of immune cells, especially non-classical monocytes  
A method of identifying non-classical monocytes in a sample, comprising analyzing the methylation status of at least one CpG position in the mammalian gene region within the 2213 amplicon,...
DE102017125019B4 PDCD1 as an epigenetic marker for the identification of immune cells, in particular PD1 + cells  
A method of identifying PD1 + cells in a sample, comprising analyzing the methylation status of at least one CpG position in the mammalian gene region for Programmed cell death 1 (PDCD1),...
DE102017125013B4 MCC as an epigenetic marker for the identification of immune cells, in particular basophilic granulocytes  
A method of identifying basophil granulocytes in a sample comprising analyzing a modification such as the methylation status of at least one CpG position in the mammalian gene region for mutated...
DE102017125150B4 Endosialin (CD248) as an epigenetic marker for the identification of immune cells, in particular naïver CD8 + T cells  
A method of identifying naive CD8 + T cells in a human-derived sample comprising analyzing a modification such as the methylation status of at least one CpG position in the human endosialin gene...
DE112016007245T5 Method for detecting target nucleic acid molecules  
The present invention provides a method for detecting a target nucleic acid molecule with high sensitivity by using FRET. The method for detecting a target nucleic acid molecule according to the...
DE102017125013A1 MCC as an epigenetic marker for the identification of immune cells, in particular basophilic granulocytes  
The present invention relates to a method, in particular an in vitro method for the identification of basophilic granulocytes, comprising the analysis of a modification such as the methylation...
DE202017006951U1 Multiplex assays to assess prostate cancer status  
A solid phase assay system comprising: a chip, which has a substantially rigid substrate and two or more liquid-insulated containment areas, wherein each fluid containment region has one or more...
DE102016124844B3 DNA probes for in situ hybridization of chromosomes  
Kit, probe mixtures and probes for the detection of a chromosome aberration. A gene probe obtained by a method comprising the following steps: (a) examining genomic sections for sequence regions...
DE10145814A1 Use of a gene in the gene coding for the GNB3 β3 subunit of human G proteins  
The invention relates to sequence variants of the human gene GNB3, encoding the Gbeta3 subunit of human G proteins, and their use for predicting the success of pharmacological and...
DE10136656A1 Biochip useful e.g. for determining gene expression patterns, and for selecting probes, comprises probes specific for genes active in rat liver  
A biochip has many probe positions, each containing many molecules of a nucleic acid probe (I), where one (I) has a length of 20 bases identical with, or complementary to, a segment of a rat liver...
DE10021834A1 New mRNA indicative of T cell activation and functional status, useful for diagnosis and therapy e.g. of autoimmunity or transplant rejection  
Messenger RNA, (mRNA), (I), for use as indicator of the activation and functional status of T cells, that have increased or reduced expression, and are present at higher or lower concentration, in...
DE10106643A1 Detection probes used in bioassays e.g. for determining nucleic acids, based on luminescent doped inorganic nanoparticles which are detectable after irradiation source and can be coupled to affinity molecules  
Simple detection probe (SDP) contains luminescent doped inorganic nanoparticles (I), which after excitation with a radiation source are detectable by absorption, scattering and/or diffraction of...
DE10001140A1 Oligonucleotides for the amplification and detection of bacterial genes for extracellular alkaline metallopeptidases (Apr), neutral metallopeptidases (Npr) and serine peptidases (Spr)  
The present invention relates to oligonucleotides for detecting bacterial genes which code for extracellular alkaline metaloproteases, extracellular neutral metaloproteases and extracellular serin...
DE19821114A1 Method for the identification and representation of inter-individual DNA sequence differences  
The invention relates to a method for identifying and representing interindividual differences of DNA sequences. The invention is characterized in that; the genomic DNA of the individuals to be...
DE19713556A1 Identification of eukaryotic, prokaryotic and viral species e.g. E. coli, B. subtilis and H. influenzae  
Identification of eukaryotic, prokaryotic and viral species comprises determining relative and absolute oligonucleotide frequencies comprising denaturing fragmented genomic DNA or RNA from a...
DE19712332A1 A method of detecting microsatellite instability of tumor diagnostics  
The invention relates to a method for determining genomic instability on 5 selected microsatellite loci. The analysis of these selected loci is suitable for the generation of prognostic tumor...
DE19533354A1 Nucleic acid assay  
Process for detection of nucleic acids in aqueous solution, is characterised in that: (a) at least one 2nd nucleic acid is bound or bindable to a solid phase, such that after interlinking of a 1st...
DE19525284A1 aestivum microsatellite markers for plants of the species Triticum and the tribe Triticeae and their use  
The invention pertains to novel genetic markers for wheats (Triticum aestivumL.) and closely related species (tribe: Triticeae) and to the use of these markers. The aim of the invention is to...
DE19617261A1 In-vitro skin compatibility assay  
Skin compatibility assay comprises exposing a keratinocyte culture to a potentially noxious substance and determining any change in the extra- or intracellular concns. of inflammation-associated...
DE4431432A1 Isolation of DNA from biological prepn(s). and amplification of highly degraded DNA  
Process for isolating DNA from biological prepns. comprises digesting proteins by incubation with a 1-2.5 mg/ml protease soln. for several hours, incubating the resulting soln. again in a closed...
DE4424263A1 New 3'-derivatised oligo:nucleotide analogues  
3'-Derivatised oligonucleotide analogues of formula (I) and (II) and their salts are new: R<1>-(A<1>)n'-(B<1>)m'-(A<2>)n-(B<2>)m-B<3> (I); R<1>-(A<1>)n'-(B<1>)m'-(A<2>)n-A<3> (II); A<1> and A<2> =...
DE4420737A1 New 3'-derivatised oligo:nucleotide analogues  
3'-Modified oligonucleotides (I) and (II) and their salts are new. In the formula, Q = gp. (a), i.e. cpds. (I), or gp. (b), i.e. cpds. (II); a,b = 0-20; R<1> = H; alkyl, alkenyl or alkynyl with up...
DE4337009A1 Genetic engineering method for demonstrating the recessive red factor in cattle  
Problem: At present there is no method for identifying carriers of the red factor in cattle by the genotype although there is a need. Solution to the problem: Using the polymerase chain reaction...
DE4416446A1 Sequences specific for human DNA  
Nucleotide sequences which can be used for the species-specific detection of human nucleic acids. The oligonucleotides are derived from parts of the human cytoplasmic beta -actin gene which are...
DE4242638A1 Analysing transcription patterns of gene and multi-gene families  
Analysis of transcription patterns of gene or multigene families comprises (1) isolating RNA from the relevant organ, tissue, cell line or individual cell, and subjecting it to reverse...
DE4233782A1 Human embryonal kinase 2-receptor protein - useful in tumour diagnosis and therapy  
The following are new: (A) The HEK2 (human embryonal kinase 2)-receptor protein, which has the sequence (contg. 990 amino acids) given in the specification or a variant of this sequence; (B)...
DE3935022A1 polynucleotide  
A method for the assessment of sample DNA fragmentation which comprises detecting the presence or absence of a control fragment formed, during sample DNA cleavage, after one or more of the DNA...
DE3829535A1 Nucleic Acid Fragments from eukaryotic genomes, PROCESS FOR THEIR PRODUCTION AND THEIR USE FOR THE DETECTION OF RESTRICTION FRAGMENT length polymorphisms (RFLPs)  
Described are nucleic acid fragments from eukaryotic genomes suitable for the detection of restriction fragment length polymorphisms (RFLPs) in eukaryotic genomes. They are obtainable by screening...
DE3904270A1 METHOD FOR MARKING OF CERTAIN CHROMOSOMES USING REPETETIVER recombinant DNA  
A method is provided for determining specific nucleotide sequences useful in forming a sample that can be used to identify specific chromosomes, preferably by in situ hybridization with the cell...
DE3742706A1 Method for identifying unknown biological material  
The specificity of proteins has been used to date to identify the origin of a biological material. The invention relates to a method for identifying unknown biological material, wherein DNA of the...
DE3737237A1 ANTICOAGULATORISCHES PROTEIN PP4-X, ITS PRODUCTION AND USE  
The protein PP4-X, whose amino acid sequence and the DNA sequence coding for it has been determined, has anticoagulant properties and can be produced by genetic engineering. PP4-X is used for...
DE3724488A1 Method for analysing the origin of biological material which is no longer metabolically active in vivo  
The method is characterised in that, after digestion of the biological material which is no longer metabolically active in vivo, deoxyribonucleic acid (DNA) is liberated, isolated and determined...
DE3720754C1 Isolation of specific RNA and/or DNA  
Complexes consist of a nucleic acid (RNA or DNA) which is bound via a hybridisation to an oligonucleotide probe (ONP) complementary thereto, where the oligonucleotide probe (ONP) is linked to a...
DE3542024A1 HLA-B 27, DNA coding therefor and the use thereof  
The cDNA for HLA-B 27 has been obtained from a cDNA library and can be used, on the one hand, as diagnostic aid and, on the other hand, as starting material for the preparation of HLA-B 27 by...

Matches 1 - 40 out of 40