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DE102019106194A1 Device for the spectroscopic determination of the binding kinetics of an analyte  
The invention relates to a device for the label-free quantitative spectroscopic determination of the binding kinetics of an analyte. Essential components of the device, namely a light source (2),...
DE102019202788A1 Method for counting cell types or cell markers in a sample, in particular in a blood sample  
The invention relates to a method for the detection of certain characteristic cells in a sample, comprising the following steps: a) Providing a sample of cell suspension 1b) Carrying out a first...
DE102019202786A1 Method and control device for determining positions of probe sections for a microfluidic device and microfluidic system  
The invention relates to a method for determining positions of probe sections (124) for a microfluidic device (110). The probe sections (124) are designed to generate luminescence in the event of...
DE102019202175A1 Microfluidic device and method for binding target particles contained in a fluid  
The invention relates to a microfluidic device (105). The microfluidic device (105) comprises a separation chamber (115), a first channel (120) fluidly connected to the separation chamber (115)...
DE102018126183B4 Method for determining the concentration of a fluorescent and / or fluorescence-labeled analyte and calibration method for preparing this determination  
Calibration method used in preparation - the determination of the concentration of a sample Psample of a fluorescent and / or fluorescence-labeled analyte, with the following steps: - Provision of...
DE102018112644B4 CXCR3 as an epigenetic marker for the identification of inflammatory immune cells, in particular CD8 + memory T cells  
A method for specifically identifying the CXC motif chemokine receptor 3 (CXCR3) subpopulation of immune cells in a mammalian sample comprising immune cells, comprising analyzing the methylation...
DE102018218047A1 Shielding device for a chip laboratory analyzer, chip laboratory analyzer and method for operating a chip laboratory analyzer  
The invention relates to a shielding device (105) for shielding a light path (107) between an optical unit (110) of a chip laboratory analysis device (100) and a chip laboratory cartridge (115)...
DE102018218046A1 Filter device for an optical module for a chip laboratory analyzer, optical module for a chip laboratory analyzer and method for operating an optical module for a chip laboratory analyzer  
The invention relates to a filter device (130) for an optical module for a chip laboratory analysis device. The optics module has a light path. The filter device (130) comprises a carrier element...
DE102018126251A1 Filtering device  
The invention relates to a device (1) for isolating at least one substance from a sample, comprising a filter module (2) with a sample inlet (3a), a sample outlet (3b) and a filter element (4) for...
DE102018126183A1 Method for determining the concentration of a fluorescent and / or fluorescence-labeled analyte and calibration method for preparing this determination  
The invention relates to a method for determining the concentration of a fluorescent and / or fluorescence-labeled analyte and a calibration method for preparing this determination, for use in the...
DE102018125324A1 Procedure for predicting an answer to disease therapy  
The present invention relates to a method of predicting a response to disease therapy, preferably tissue regeneration, preferably cardiovascular regeneration, comprising the use of a biomarker....
DE102018216872A1 Analysis method for mRNA of individually light-irradiated cells  
Method for analyzing the nucleic acids, in particular the mRNA of cells that have been individually irradiated with light. In the method, nucleic acid constructs are introduced into cells in order...
DE102012107718B4 Calibration sample based on DNA origami  
Use of a calibration sample of structures based on DNA origami, which have at least two marker molecules at predetermined positions which are spaced apart from one another in the DNA origami, and...
DE102018218739B3 Blood collection tube and preparation method  
The invention describes a method for stabilizing a liquid biological sample with the step of drawing the sample into a first end of a tube which has a preset vacuum and / or at the opposite second...
DE102018002234B4 Trichoderma fungus strain and method for promoting plant growth  
Fungus strain of the genus Trichoderma with the designation HSA12, which was deposited on January 12, 2018 under the patent deposit number DSM 32722 with the Leibniz Institute DSMZ - German...
DE102018213587A1 Method for determining a specificity of a real-time polymerase chain reaction with a melting curve analysis  
The invention relates to a method (500) and a device (100) for determining the specificity of a real-time polymerase chain reaction, wherein a real-time polymerase chain reaction (501) is carried...
DE102006042044B4 Method for measuring the smallest local magnetic fields, in particular for measuring local magnetic stray fields generated by magnetic beads, and associated device for carrying out the method  
Method for measuring the smallest local magnetic fields, in particular for measuring local magnetic stray fields generated by magnetic beads, with the following measures: at least one...
DE102018210710A1 Microfluidic device and method for the detection of a target protein of a biological sample  
The invention relates to a device (100), in particular a microfluidic device (100), and a method (500) for detecting a target protein (10) of a biological sample, comprising a sample chamber (111)...
DE102018210664A1 Microfluidic flow cell and method for separating nucleic acids  
The invention relates to a microfluidic flow cell (100) and a method (600) for separating nucleic acids, the flow cell (100) having electrodes (103, 104) for generating an electric field in the...
DE102018115391A1 Assay, process for its preparation and its use  
The invention relates to an assay for the analysis of a complex analyte. The assay (1) comprises at least one layer (10), which comprises: • a porous three-dimensional polymer network (11) with a...
DE102018112644A1 CXCR3 as an epigenetic marker for the identification of inflammatory immune cells, in particular CD8 + Gedächnis T cells  
The present invention relates to a method, in particular an in vitro method, for the specific identification of the CXC motif chemokine receptor 3 (CXCR3) subpopulation of immune cells in a sample...
DE102018207379A1 Method for operating a motor vehicle system on the basis of a user-specific user setting, storage medium, assignment device, motor vehicle and server device for operating on the Internet  
The invention relates to a method for operating a motor vehicle system (20) on the basis of a user-specific user setting. An allocation device (12) performs: on the basis of a provided (S1) gene...
DE102018207106A1 Microfluidic sequencing device for the amplification and separation of molecular chains and method for separating molecular chains obtained from an amplification reaction  
The invention relates to a microfluidic sequencing device (100) for amplifying and separating molecular chains, wherein the sequencing device (100) is adapted to receive biochemical material. The...
DE102018207101A1 A method for producing a bottom of an analysis cell for analyzing a biochemical material and analysis cell  
The invention relates to a method for producing a bottom (102) of an analysis cell (100) for analyzing a biochemical material (101). Here, carbon-rich precursor molecules and low-carbon precursor...
DE102018207099A1 A method of making a sequencing unit for sequencing a biochemical material and sequencing unit  
The invention relates to a method for producing a sequencing unit (100) for sequencing a biochemical material. At least one sequencing pore (104, 114) for sequencing the biochemical material in a...
DE102018207098A1 Microfluidic device and method for nanostructure sequencing of nucleotide strands  
The invention relates to a microfluidic device (100) and a method (600) for sequencing nucleotide strands comprising an array unit (200) and a nanostructure (300) connected to the array unit...
DE112017006899T5 Analysis system and analysis method  
An analysis system includes an analyzer designed to chromatographically separate a sample having a plurality of components labeled with the M types of fluorescent substances and to obtain first...
DE202018006254U1 Gene detection kit and gene detection device  
A gene detection kit for realizing a gene detection method, comprising: a box body having a hinged lid on an upper surface, a lysing portion and a washing portion separated by the plunger being...
DE112018000184T5 Automated machine for sorting biological fluids  
One technique relates to a sorting machine. A removable cassette contains a nanofluid module. The removable cassette includes an entrance opening and at least two exit openings. The nanofluid...
DE102018002234A1 Mushroom strain of the genus Trichoderma and method of promoting plant growth  
The invention relates to a fungus strain of the genus Trichoderma called HSA12 and compositions containing this fungus strain or its spores. Furthermore, the invention relates to the use of the...
DE102018104133A1 Biomarkers to detect a possible intolerance to metal implants  
The invention relates to a method for predicting an increased risk of increased intolerance to metal implants. The object of the present invention is to improve the prognosis of possible...
DE102018001512A1 Drug Primary Performance Monitoring Assay for the simultaneous determination of an analyte and a therapeutic agent directed against the analyte  
The invention relates to a test for controlling primary drug effects (Drug Primary Performance Monitoring Assay), in which a simultaneous quantitative determination of an analyte and a directed...
DE102018107224A1 Peptides and combinations of peptides of non-canonical origin for use in immunotherapy against various cancers  
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic procedures. In particular, the present invention relates to the immunotherapy of cancer....
DE112017006114T5 DNA ANALYSIS DEVICE AND DNA ANALYSIS METHOD USING THE TERAHERTZWELLE  
The present invention relates to a DNA analysis apparatus or a DNA analysis method using the terahertz wave, which makes it possible to accurately detect a cancer by means of the terahertz wave...
DE112017004738T5 Determination of molecular structures and molecular arrangement structures from momentum transfer cross-section distributions  
Systems and methods are provided for de novo determinations of molecular structures or molecular arrangements, including biologically relevant protein structures or assemblies, exclusively from...
DE10262193B4 Cosmetic use of an active substance for stimulating type 2 and / or type 3 human beta-defensins, use of such an active substance for the preparation of a pharmaceutical composition containing such an active substance and use of such an active substance in the field of tissue reconstruction  
Cosmetic use of an active substance, which is selected from the group consisting of a Boldo extract, a cocoa extract and jasmonic acid, wherein the extract is obtained by aqueous extraction or...
DE102017130322A1 Method and kit for the specific detection of diagnostically relevant proteins in biological samples  
The invention relates to a method for detecting at least one target protein in a sample containing proteins, comprising the steps: i. Sample preparation (eg homogenization, dilution etc. of the...
DE102017220531A1 Adapter for a microfluidic device for transferring a substance, in particular a sample  
The invention relates to an adapter (100) for a microfluidic device (200), wherein the adapter (100) has a substance input chamber (111, 112, 113) and a connection channel (151, 152) fluidly...
DE102017010842A1 A method of quantifying protein aggregates of a protein misfolding disease in a sample  
The invention relates to a method for quantifying protein aggregates of a protein misfolding disease in a complex sample. A device, a kit and a use of the device and the kit are disclosed.
DE102018001796B4 GENES IN SANDERIA MALAYENSIS RESPONDING TO RISING SEAWATER TEMPERATURES, AND METHOD FOR PREDICTING PHYSICAL OR METABOLIC CHANGES OF SANDERIA MALAYENSIS  
A microarray chip for the detection of a strong stress stress strain of Sanderia malayensis on which oligonucleotides which form any nucleic acid sequence of those genes represented by SEQ. ID....
DE102016108115B4 Sample buffer with low molecular weight dye stabilizer for gel electrophoresis  
A sample buffer (100) for loading with a fluidic sample (106) to be separated, the sample buffer (100) comprising: a fluorescent dye (102) for coupling to the fluidic sample (106); a dye...
DE102017125335A1 Amplicon region as an epigenetic marker for the identification of immune cells, especially non-classical monocytes  
The present invention relates to a method, in particular an in vitro method for identifying non-classical monocytes, comprising analyzing the methylation status of at least one CpG position in the...
DE102017125150A1 Endosialin (CD248) as an epigenetic marker for the identification of immune cells, in particular naïver CD8 + T cells  
The present invention relates to a method, in particular an in vitro method, for identifying specific immune cells, in particular naive CD8 + T cells, comprising analyzing the methylation status...
DE102017218849A1 Reaction carrier for a microfluidic device and method for determining a nucleotide sequence  
The invention relates to a reaction support (100) for a microfluidic device (200) for determining a nucleotide sequence, comprising at least a first recess (101) and a second recess (102), wherein...
DE102017125019A1 PDCD1 as an epigenetic marker for the identification of immune cells, in particular PD1 + cells  
The present invention relates to a method, in particular an in vitro method, for identifying PD1 + cells comprising the analysis of epigenetic modifications / properties (including methylation...
DE102017214449B4 Method and means for the diagnosis of tumors by detection and quantification of heterogeneously methylated epialleles  
The invention relates to methods and means for the diagnosis of tumors, in particular for the early diagnosis and for the differentiation of benign and malignant tumors by means of digital PCR, in...
DE102017214449A1 Method and means for the diagnosis of tumors by detection and quantification of heterogeneously methylated epialleles  
The invention relates to methods and means for the diagnosis of tumors, in particular for early diagnosis and for distinguishing benign and malignant tumors by means of digital PCR, especially in...
DE112016006855T5 Method and apparatus for analyzing biomolecules  
The purpose of the invention is to provide a method for analyzing biomolecules, with which it is possible to suppress the clogging of nanopores with ease. The first embodiment of the invention is...
DE102017007521A1 DNA Security Concept and a biological-chenisches pocket laboratory - as a basis for modern security systems and the forensic analysis of the smallest traces  
A completely new individual and absolutely forgery-proof security concept is presented, based on the unique DNA of the individual. The human DNA (Deoxyribonucleicacid) can be described on any...
DE102018001796A1 GENESIS IN SANDERIA MALAYENSIS RESPONSE TO THE RISING TEMPERATURE OF SEAWATER, AND METHOD FOR PREDICTING THE PHYSIOLOGICAL OR METABOLOGICAL CHANGE OF SANDERIA MALAYENSIS  
The present invention relates to a Sanderia malayensis gene which responds to rising seawater temperature and to a method of predicting physiological or metabolic changes of Sanderia malayensis...