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DE102019114011B3 Method and device for extracting and / or reproducing a target nucleic acid  
The invention relates to a method for extracting a target nucleic acid (22) from a sample liquid (500). The method comprises providing a heating device with a heating element (10) in contact with...
DE102011123079B3 Modified nucleotides  
Modified nucleotides and methods for modifying nucleotides with a structural unit or label, such as biotin, that enable their detection and result in a modified nucleotide, and methods of using...
DE102016120124B4 A method of conducting a polymerase chain reaction and apparatus for carrying out the method  
A method of amplifying nucleic acids by means of a polymerase chain reaction in a reaction volume in which the reaction volume is heated by the use of electrical energy, characterized in that in...
DE102016120124A1 Method for performing a polymerase chain reaction and apparatus for carrying out the method  
The invention relates to a method for multiplying nucleic acids by means of a polymerase chain reaction in a reaction volume, in which the reaction volume is heated by the use of electrical...
DE10113265B4 Use of a stabilized nucleic acid for the production of a protein  
The invention teaches the use of a linear nucleic acid stabilized against exonuclease degradation in a method of producing a protein encoded by a base sequence of the nucleic acid in a cell-free...
DE102013022382B9 Process for the amplification of nucleic acids  
The invention relates to a method for the amplification of nucleic acids (1) in a sample (12), the method comprising a amplification step for amplification of the nucleic acids and a test step for...
DE102011018627B4 Modified nucleotides  
Connection with structure (I): or a salt, a conjugate base, a tautomer or a dissociated form thereof, wherein P1 is a phosphate group; P2 is a phosphate group; Nus is a nucleoside structural unit...
DE102013022382B3 Process for the amplification of nucleic acids  
The invention relates to a method for the amplification of nucleic acids (1) in a sample (12), the method comprising a amplification step for amplification of the nucleic acids and a test step for...
DE112013004774T5 Trophic conversion of photoautotrophic bacteria to improve the tag properties  
The present disclosure relates generally to the growth of recombinant bacterial cells from species under photoautotrophic Tagbedingungen. In particular, the present disclosure relates to isolated...
DE112013004650T5 Multiplexpyrosequenzierung using nichtinterferierender, noise-terminating Polynukleotididentifikationstags  
The present disclosure relates generally to a multiplexing method for analyzing samples, comprising the Polynukleotidamplifikation to production of amplified products, wherein one or more target...
DE102012201475B4 Process for the amplification of nucleic acids  
A method for the multiplication of nucleic acids (1) in which nanoparticles (8) in a reaction volume (2) transfer heat to their surroundings by excitation.
DE102012201475A1 Process for the amplification of nucleic acids  
A method for the multiplication of nucleic acids (1) in which nanoparticles (8) in a reaction volume (2) transfer heat to their surroundings by excitation.
DE602004036672C5 Nucleic acid-based emulsion beads  
Method for enriching an amplicon comprising: (A) distributing an amplification solution, which comprises a sufficient mixture of reagents that are required for carrying out an amplification...
DE102012008375A1 Methods and components for the detection of nucleic acid chains  
The invention describes a new method for the enzymatic labeling of nucleic acid chains (target sequences) with nucleotide conjugates. These nucleotide conjugates are able to bind specifically to...
DE102009024757B4 Methods and devices for controlling a chemical reaction using pressure using high-pressure-optimized biocomponents  
Method for controlling a chemical reaction by means of pressure using high-pressure-optimized biocomponents, a combination of high-pressure-optimized and low-pressure-optimized biocomponents,...
DE102004050510B4 Process for valve control in the thermocycling of a substance for the purpose of PCR and related assembly  
Process for thermocycling of a substance for the purpose of carrying out a PCR, - Wherein a sample liquid is subjected to a PCR chamber (120) by cyclically heating and cooling a predetermined...
DE102009024757A1 Methods, compositions and devices for controlling a chemical reaction by means of pressure using high-pressure optimized biocomponents  
The present invention relates to methods, compositions and devices for controlling a (bio) chemical ROUP by compressed using high pressure-optimized bio.In the methods and compositions of the...
DE102009012169B3 Device and method for producing a replica or a derivative of an array of molecules and applications thereof  
A method of manufacturing a replica, or a derivative of an array of molecules wherein said array having a spatial array of separate samples of molecules, said generating comprises at least one...
DE10106493B4 A process for the production of nucleic acids  
A process for the preparation of nucleic acids comprising the steps of Bacterial cells contained (a) Cultivation of the nucleic acid in a medium without components and complex (B) isolating the...
DE102006056694B4 A method for performing an enzymatic reaction  
A method for performing an enzymatic reaction with an at least one eukaryotic cell containing sample comprising the steps of: a) providing a least one eukaryotic cell containing feedstock, b)...
DE102008008313A1 Amplification of nucleic acids bisulfited  
The present invention relates to a reaction mixture for the amplification of nucleic acids, whose unmethylated cytosine bases are converted to uracil by means of a Bisulfitierungsreaktion....
DE102008054480A1 Direct sequencing by ATP release  
There is provided a method for sequencing a nucleic acid. In certain embodiments, the method comprises contacting a nucleic acid duplex comprising a template and a nucleic acid annealed to the...
DE3752392T2 A stable enzyme composition comprising a thermostable nucleic acid polymerase  
A purified thermostable enzyme is obtained that has unique characteristics. Preferably the enzyme is isolated from the Thermus aquaticus species and has a molecular weight of about 86,000-90,000...
DE102007001370A1 RNA encoded antibody  
The This application describes an antibody coding, unmodified or modified RNA and their use for the expression of this antibody for the preparation of a pharmaceutical composition, in particular a...
DE102006056694A1 A method for performing an enzymatic reaction  
On A method for performing a enzymatic reaction, in particular for performing a PCR comprising Taking at least one eukaryotic cell from a starting material, staining the nucleus or nuclei of...
DE102007045173A1 Nucleotide analogs useful for nucleic acid synthesis or sequencing comprise a nucleotide component, a sterically demanding macromolecular ligand, a label and a linker  
Nucleotide analogs (I) comprising a nucleotide component, a sterically demanding macromolecular ligand, a label and a linker are new. Independent claims are also included for: (1) nucleic acid...
DE102006039479A1 Programmable oligonucleotide  
The Invention relates to methods and apparatus for the preparation of synthetic nucleic acids.
DE3890998B4 Neutrophilenaktivierungsfaktor, process for its preparation and pharmaceutical composition containing it  
Neutrophilenaktivierungsfaktor (NAF) which is derived from human monocytes and the following amino acid sequence comprising:...
DE102006020885A1 Inserting a tag sequence into a nucleic acid comprises using an anchor oligonucleotide comprising a hybridizing anchor sequence and a nonhybridizing tag-template sequence  
Inserting a tag sequence into a nucleic acid comprises hybridizing an anchor sequence of an anchor oligonucleotide to a sequence segment of a template nucleic acid and synthesizing a new nucleic...
DE19720839B4 Modular technology for the production of long, exact DNA constructs in vitro, in particular for the preparation of constructs for the production of artificial chromosomes (MAC, mammalian artificial chromosome) of two stable cloned DNA components and the prototype vector ditelomerische PTAT  
process for in vitro production of about 50 Kb long DNA constructs by directed, site-specific Recombination, characterized in that it comprises the steps of: a) Independent cloning of two DNA...
DE102005053463A1 Apparatus and method for automated isolation and purification of nucleic acids from any complex starting materials  
object of the invention are an apparatus and a method for automated Isolation of nucleic acids from nucleic acid-containing different starting materials. The reaction unit of the invention...
DE112004002318T5 Transcriptional regulators and method thereof  
process to determine which genes of a subset of genes by a in a cell expressing transcriptional regulator are regulated, wherein the method comprising: (a) selectively isolating chromatin from the...
DE102005023055A1 Making DNA fragments for determining DNA methylation pattern involves digesting DNA with methylation-specific restriction enzyme; and ligating adapters to restriction fragments, followed by primer mediated-amplification of ligated fragments  
Making a selected mixture of DNA fragments involves obtaining a solution comprising genomic DNA; digesting the genomic DNA with at least one methylation-specific restriction enzyme, where the DNA...
DE102004050510A1 Process for valve control in the thermocycling of a substance for the purpose of PCR and related assembly  
It to an arrangement for the thermocycling a substance created will. Here are inventively following measures carried out: After the introduction of the sample liquid close in the PCR chamber...
DE10333389A1 Use of cell organelles for stabilizing biomolecules and cells, useful e.g. in cell replication or in vitro translation or transcription systems, particularly mitochondria  
Use of cell organelles (A) for stabilization of biomolecules and cells (B) in extracellular aqueous media, is new.
DE10355593B4 Process for the hybridization of biological macromolecules bound to a solid surface PCR products  
process for hybridization of biological macromolecules on bonded to a solid surface PCR (polymerase chain reaction) products with the following steps: a) Providing a solid surface with at least...
DE102004017369A1 Screening method for the identification of PUFA-PKS in sample  
The Invention describes a method for quick and easy identification of PUFA PKS in microorganisms. It is characterized by a in vitro propagation of DNA segments specific for PUFA (polyunsaturated...
DE10163313B4 Method and device for influencing a reaction of which is arranged in a medium reactants  
process for influencing a reaction from existing in a medium Reactants by supplying energy, characterized in that in the medium at least one micro-absorber with energy, which of the Material micro...
DE102004009977A1 New nucleic acid containing fluorescent tricyclic heterocyclic residue, useful as hybridization probes for detection and quantification of nucleic acids  
Nucleic acid (A) comprising a backbone to which at least one tricyclic heterocyclic group (I) is attached is new. Nucleic acid (A) comprising a backbone to which at least one tricyclic...
DE102004009704A1 New conjugates useful for labeling nucleic acids comprise a label coupled to nucleotide or nucleoside molecules through polymer linkers  
Conjugates (I) comprising a label coupled to 1-100 nucleotide or nucleoside molecules through polymer linkers with a length of 100-20000 atoms are new. Conjugates of formula (I) are new....
DE102004002351A1 New RNA aptamers specific for lipopolysaccharide-binding protein, useful for diagnosis and treatment of sepsis, inhibit the lipopolysaccharide-induced signaling cascade  
RNA aptamers (I), or their alleles and/or derivatives, that bind specifically to lipopolysaccharide-binding protein (LBP) are new. An independent claim is also included for a method for preparing...
DE10357677A1 Primers and probes for the detection of genital HPV genotypes  
The present invention relates to oligonucleotides as primers for suitable amplification of DNA of genital human papilloma viruses (HPV) are oligonucleotides that genital as probes to type HPV...
DE10355593A1 Process for the hybridization of biological macromolecules bound to a solid surface PCR products  
The Invention relates to a method for hybridization of biological macromolecules on bonded to a solid surface PCR products in which a solid body surface with provided at least one spot having...
DE10353887A1 High parallel DNA synthesizer to die base  
The Invention relates to a process for the preparation of nucleic acid double strands on die base.
DE102004046388A1 Quantification of nucleic acids using growth curves  
It Techniques for determining a target nucleic acid amount ( "Target") in a sample using methods, devices and systems, including Computer program products, executed. are signal data for multiple...
DE10349441A1 Selecting nucleic acid that binds target molecules, useful potentially as therapeutic agents, by screening short sequences with two fixed regions flanking a random region  
Selecting a nucleic acid (I), especially an aptamer, that binds a target molecule (II), is new. Selecting a nucleic acid (I), especially an aptamer, that binds a target molecule (II) comprises:...
DE10342373A1 A process for the synthesis of nucleic acids and their uses  
The This invention relates to a process for the synthesis of a Nucleic acid, wherein the nucleic acid comprises modified nucleotides comprising the steps of:- Provide a template strand;- Providing...
DE10253966B4 Microarray-based method for the amplification and detection of nucleic acids in a continuous process  
process for efficient amplification of at least one template nucleic acid, characterized in that the nucleic acid amplified by a PCR is, wherein the reaction already at the beginning of at least...
DE19725371B4 A method for accelerating the evolutive optimization of biopolymers and improving the biopolymers produced therewith  
process to accelerate the evolutionary optimization of biopolymers and to improve the biopolymers produced therewith in a process with a set of single or double nucleic acid chains, and at least...
DE19610255B4 Process for the preparation of nucleic acid sequences and methods for detecting translocations between chromosomes  
process for the preparation of a nucleic acid the for a Translokationsbruchpunkt on a chromosome is specific, comprising a first sequence portion to a DNA sequence is a first chromosome...

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