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DE102016124844B3 DNA probes for in situ hybridization of chromosomes  
Kit, probe mixtures and probes for the detection of a chromosome aberration. A gene probe obtained by a method comprising the following steps: (a) examining genomic sections for sequence regions...
DE10328887B4 Alkaline protease  
Alkaline protease with a prepro sequence, the prepro sequence being a mutated sequence of the amino acid sequence of SEQ ID NO. 1 represents or an amino acid sequence with at least 80%, 87%, 90%,...
DE19858588B4 The dye-labeled oligonucleotide for labeling a nucleic acid molecule  
The dye-labeled oligonucleotide for labeling a a target sequence section comprising a nucleic acid molecule, wherein the dye-labeled oligonucleotide comprises the following components: a) - a loop...
DE112013004650T5 Multiplexpyrosequenzierung using nichtinterferierender, noise-terminating Polynukleotididentifikationstags  
The present disclosure relates generally to a multiplexing method for analyzing samples, comprising the Polynukleotidamplifikation to production of amplified products, wherein one or more target...
DE4321904B4 A process for chromatographic purification and separation of Nucleinsäuregemischen  
A process for chromatographic purification and separation of Nucleinsäuregemischen from biological sources such as cell cultures, tissues, body fluids, microorganisms or viruses to be separated by...
DE4420157B4 New growth / differentiation factor of the TGF-β family  
Use of a pharmaceutical composition containing a protein which is encoded by a DNA sequence which (a) nucleotides 1783-2142, 640-2142 or 1837-2142 of SEQ ID NO: 1, (b) one of the sequences from...
DE102010038842A1 New aptamer that specifically binds to human tau protein or its fragment, useful e.g. in vitro for isolating, purifying and/or detecting tau protein, and to treat cerebral infarction, pick disease and/or progressive supranuclear palsy  
Aptamer that specifically binds to human tau protein or its fragment, is new. Independent claims are included for: (1) kit comprising the aptamer; (2) a method for the purification of human tau...
DE102010033102A1 Determining a locus change i.e. single nucleotide polymorphism on male cattle, comprises determining the weight and/or the proportions of a fetus by molecular markers  
Determining a locus change on male cattle, comprises determining the weight and/or the proportions of a fetus by molecular markers. Independent claims are included for: (1) primers for detection...
DE102009046982A1 Solid phase bound nucleosides  
The invention relates to solid phase-bound nucleosides in which the nucleoside is covalently bound to a solid phase via a 3'-O-disulfide bridge, and to a method for their production and their use.
DE102009046981A1 Process for the production of trinucleotides  
The invention relates to a method for producing protected trinucleotides using a combination of specific protective groups.
DE102009032502A1 Detection of antigens  
The invention discloses a method for detecting at least one antigen, which comprises the following steps: providing magnetic beads which are coated with specific antibodies for at least one...
DE10103509B4 Phosphoserinphospatase gene of coryneform bacteria  
Protein, defined by (A) or (B): (A) a protein which comprises an amino acid sequence of SEQ ID No 2 of the sequence list. or(B) a protein comprising an amino acid sequence including substitution,...
DE102008064184A1 Method for increasing the sucrose yield in agricultural cultivation of sugar beet and sugar  
Use of a nucleic acid which is suitable in a plant cell to reduce the enzymatic activity of an invertase, for forming a sucrose storage organ of a plant, wherein the sucrose concentration compared...
DE102004062386B4 Monacolin K biosynthesis genes  
An isolated DNA molecule comprising a polynucleotide which it is mkA and which has a nucleotide sequence of SEQ ID NO: 2, wherein said polynucleotide encodes a polypeptide having an activity...
DE202009017108U1 Monoclonal antibody to Microcephalin (MCPH1)  
A monoclonal antibody or fragment thereof, characterized in that it specifically binds to Microcephalin (MCHP1) and recognizes an epitope which is located in the area of ​​amino acids 1 to 267 of...
DE102005031755B9 Salmonella spp. binding peptides, nucleic acids coding therefor, their uses, and methods and kits for the enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE69029370C5 Erythropoietin isoforms  
An isolated biologically active erythropoietin isoform having a single isoelectric point and having a specific number of sialic acids per erythropoietin molecule, said number being selected from...
DE10237691B4 A method for detecting single nucleotide polymorphisms (SNP) in genes of drug metabolism and test kit for performing the method  
A method for the detection of single nucleotide polymorphisms in the cytochrome P450 genes, characterized in that a) gene segments of human CYP2 genes from a sample with the amplification primers...
DE10004815B4 Human intestinal sodium phosphate cotransporter  
Npt2B polypeptide having an amino acid sequence which is identical to the sequence SEQ ID NO. 01 and sodium phosphate co-transporter having activity.
DE19831609B4 A process for producing amino acids of the aspartate and / or glutamate family and used in the process means  
A process for microbial production of amino acids of the aspartate and / or glutamate family in which the pyruvate-carboxylase activity of a corresponding amino acid-producing microorganism is...
DE10154290B4 A method for detecting periodontal disease and caries-associated bacteria  
A method for detecting periodontal disease or tooth decay associated bacteria by amplification and hybridization, comprising the steps of A) amplifying nucleic acid to fragments from the genome of...
DE102005031755B4 Salmonella spp. binding peptides, nucleic acids encoding the Verwenduen and methods and kits for enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE10084502B4 A method for purification of nucleic acid with silicon carbide  
A method for isolating a Nucleotidpolymers from a sample, comprising the steps of: Adding silicon carbide to the sample and mixing, to bind the Nucleotidpolymer to the silicon carbide; Separating...
DE102008050273A1 Apparatus and method for synthesizing a biopolymer and method for recovering a reagent for synthesizing a biopolymer  
A Apparatus for synthesizing a biopolymer has a reaction chamber (100), an outlet (410b) connected to the reaction chamber (100) is connected, a plurality of recovery tanks (461A, 461C, 461g,...
DE102005011003B9 Method and means for the differential diagnosis of thyroid tumors  
process for the differential diagnosis of thyroid tumors to differentiate of benign tumors to malicious Tumors wherein: 1) RNA is isolated from a tissue sample of the thyroid gland, 2.) in the...
DE102007038037A1 Eukaryotic promoters for gene expression  
The Invention provides promoters prepared from yeast Arxula adeninivorans which are nitrate inducible genes of nitrate reductase (AYNR1) Nitrite (AYNI1) or the nitrate transporter (AYNT1) descended.
DE102008028357A1 New Hybrid System for Brassica napus  
The present invention relates to a conditional kerngenisch inherited Male sterility system in Brassica napus. Embodiments of the present invention provide the (Male sterile) female line precursor...
DE102005011003B4 Method and means for the differential diagnosis of thyroid tumors  
process for the differential diagnosis of thyroid tumors to differentiate of benign tumors to malicious Tumors wherein: 1) RNA is isolated from a tissue sample of the thyroid gland, 2.) in the...
DE112004002408B4 A process for obtaining an enriched population of siRNA-expressing cells  
process for obtaining cells which are capable of inhibiting RNA expressing, said method comprising: introducing at least one nucleic acid in a cell, wherein the at least one nucleic acid in the...
DE19528029B4 Magnetic polymer particles based on polyvinyl alcohol, process for their preparation and use  
process for the preparation of pearl or spherical particles of polyvinyl alcohol having a particle size in the range 1-10 microns, characterized in that aqueous polyvinyl alcohol solution, in...
DE3890998B4 Neutrophilenaktivierungsfaktor, process for its preparation and pharmaceutical composition containing it  
Neutrophilenaktivierungsfaktor (NAF) which is derived from human monocytes and the following amino acid sequence comprising:...
DE10045123B4 The C. albicans TEC1 GEN (CaTEC1) and the encoded protein Tec1p  
Nucleic acid molecule which for cloning a gene encoding a transcription factor is suitable and / or a protein having the biological activity of a transcription factor coded and as a means for...
DE19720839B4 Modular technology for the production of long, exact DNA constructs in vitro, in particular for the preparation of constructs for the production of artificial chromosomes (MAC, mammalian artificial chromosome) of two stable cloned DNA components and the prototype vector ditelomerische PTAT  
process for in vitro production of about 50 Kb long DNA constructs by directed, site-specific Recombination, characterized in that it comprises the steps of: a) Independent cloning of two DNA...
DE19903056B4 HPV Assay  
process to amplify existing in biological samples HPV DNA, characterized in that a) a sample optionally subjecting a protease digestion, b) the nucleic acids separating of protease and other...
DE102005036542A1 CTL prodrug  
The This invention relates to a polypeptide having preferably antitumoral and / or immunomodulatory Zytokineigenschaften through which Processing in vivo is activated, comprising a C-terminal...
DE19713543B4 Bacterial plasmids  
plasmid pMut1 available from E. coli DSM 6601, which after cleavage with the restriction enzyme HindIII and subcloning as linear fragment into the vector pUC18 the DNA sequence of 1 determined...
DE102005031755A1 New peptides that bind to Salmonella, useful for immobilization, detection, concentration and labeling, optionally derivatized with a pharmaceutical  
Peptide (I) that (i) contains a segment of at least 8 amino acids from any of SEQ ID NOs (1)-(36), all reproduced, and (ii) can bind to Salmonella species is new. Independent claims are included...
DE112004002408T5 A process for obtaining an enriched population of siRNA-expressing cells  
process for obtaining cells which are capable of inhibiting RNA expressing, said method comprising: introducing at least one nucleic acid in a cell, wherein the at least one nucleic acid in the...
DE102005023829A1 Alleles of opcA gene from corynebacteria  
The Invention relates to mutants and alleles of the gene of coryneform opcA Bacteria encoding Variants of the OpcA subunit of glucose-6-phosphate dehydrogenase (EC: 1.1.1.49), and methods for...
DE102005015832A1 Use of receptor multimerization epitope (RME) of advanced glycation end product receptor (AGER) as immunogen, useful for preparing antibodies for diagnosis and treatment of e.g. spinal injuries or diabetic complications  
Use of the receptor multimerization epitope (RME) of the advanced glycation end product receptor (AGER) as an immunogen for preparing polyclonal antiserum or monoclonal antibodies against AGER-RME...
DE10154254B4 sealing arrangement  
sealing arrangement at a connection between a wheel hub (11) in a wheel bearing (16) is held and on the adjacent said bearing inner ring (18) of the wheel bearing (16) is a flanged sleeve (26)...
DE19632862B4 Immunologically active proteins of Borrelia burgdorferi, nucleic acids coding therefor and the use thereof in test kits and as vaccines  
immunological active protein of Borrelia burgdorferi, the of in another present from Borrelia burgdorferi proteins derived free form, characterized in that it the sequence of the protein 1829-22A...
DE19810349B4 Chitindeacetylasegen, vector containing this gene and transformants  
Polynucleotide molecule, a the Protein deacetylase for N-acetyl groups in N-acetylated Aminozuckerresten or a functional fragment it encodes, said polynucleotide molecule (A) is a polynucleotide...
DE102004035337A1 Variants of the group 1 allergens from Poaceae with reduced allergenicity and received T cell reactivity  
The This invention relates to the preparation and use of Variants of the group 1 allergens of the Poaceae (grasses), which the by opposite known wild-type allergens reduced IgE reactivity and...
DE10231659B4 Composition for binding nucleic acid to a solid phase  
composition for binding of nucleic acids in aqueous solution to a solid phase containing a guanidinium salt, a buffering agent and a detergent, characterized in that the pH value of the solution...
DE19605657B4 Human proinsulin derivative-encoding DNA, DNA containing expression vector, transformed with this microorganism and use of this human Proinsulinderivats  
Mensc hliches Proinsulin derivative of the formula (I): B chain-ZA-chain (I)wherein: the A- and B-chains are human insulin chains respectively; Z a Peptide of formula UUXPJ- (X ') is Nuu; U an...
DE102004026494A1 Detecting specific nucleic acid comprises hybridizing peptide nucleic acid oligomer and DNA oligo where both sequences are complementary to the target and measuring fluorescent change upon mixing with target sequence which displaces oligo  
Detecting nucleic acid (I) having a predetermined sequence comprises: (a) preparing a PNA (peptide nucleic acid) oligomer (II), complementary to (I) and able to hybridize to it; (b) preparing a...
DE102004025710A1 A process for the taxon cell identification and cell sorting on gram-positive bacteria and devices therefor  
The This invention relates to a process for the taxon Cell identification and / or cell sorting on gram-positive bacteria. About that addition, the present invention provides a kit for identifying...
DE10150121B4 Real time detection of DNA amplification  
process to perform a Nukleinsäureamplifikaktion, in which transcribed in a single step reaction RNA reverse, without a Inhibiting reverse transcription occurs to the formed complementary DNA...
DE10393431T5 Microarrays with more oligonucleotides in each Array Features  
Microarray, comprising a plurality of features, each of the features single-stranded oligonucleotides comprising, at least some of the features of more oligonucleotides comprising as a sequence...