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DE112020002216T5 Procedure for improving glycosylamine detection  
The present invention relates to methods for improving the sensitivity of the detection of glycosylamines released by enzymatic cleavage from glycoconjugates such as glycoproteins or glycopeptides...
DE202015009974U1 Artificial nucleic acid molecules for improved protein expression  
Artificial nucleic acid molecule comprisinga) at least one open reading frame (ORF); and b) a 3'-untranslated region (3'-UTR) comprising at least two separate poly(A) sequences, wherein a poly(A)...
DE102020119024A1 Process for manufacturing a bio-based product, corresponding product and uses  
A method for producing a product comprising one or more bio-based substances selected from the group consisting of fatty alcohols, fatty alcohol alkoxylates, fatty alcohol polyglycosides, fatty...
DE102021204116A1 ANTI-VARICELLA ZOSTER VIRUS ANTIBODIES, IMMUNLOGICAL MEASURING METHOD AND IMMUNOLOGICAL MEASURING DEVICE  
It is an object of the present invention to provide a means for rapidly diagnosing infection with VZV. The present invention relates to an antibody against VZVgE or an antibody fragment thereof,...
DE102020111560A1 Enzyme cascades based on sucrose synthase and pyrophosphorylase to convert ADP to ATP  
The present invention relates to a method for the multistage enzymatic conversion of adenosine diphosphate (ADP) to adenosine triphosphate (ATP), the method comprising the steps: a)...
DE112019005166T5 METHOD OF SPECIFIC INSERTION OF DNA INTO GENES  
Methods and compositions for modifying the coding sequence of endogenous genes using infrequent cutting endonucleases and transposases. The methods and compositions described herein can be used to...
DE102015121190B4 USE OF AN ADSORB CONTAINING PRIMARY AMINOGRAPHY FOR A PROCESS FOR ENRICHING AND / OR PURIFYING COMPOUNDS CONTAINING ALDEHYDE AND KETO GROUPS  
Use of an adsorbent which comprises primary amino groups for a process for the enrichment and / or purification of aldehyde and keto group-containing compounds from aqueous solutions of a...
DE102020210883A1 EDGE SEQUENCING WITH AN IMMOBILIZED TRANSLOCATOR  
The present disclosure relates to systems, devices and methods for nucleic acid sequencing, including polynucleotide strands that have one or more nucleotides that are modified with one or more...
DE102019118332A1 METHOD AND TEST KIT FOR BISULFITE MODIFICATION OF DNA  
The present application relates to a method and a test kit for carrying out a reaction for bisulfite modification of DNA to determine the methylation pattern of the DNA, characterized in that...
DE102019002677A1 Process for coating electrical or other technical equipment with a new type of warning signal substance  
The present invention relates to a new substance and its special suitability for a method for coating cables, electrical or other technical devices with this warning signal substance in the event...
DE102006012415B4 Enzymatic process for the production of degraded vegetable gum  
A method for the recovery of degraded polygalactomannan, comprising the following steps: - Providing an aqueous solution of a polygalactomannan at a temperature which is in the range between 0 and...
DE102018131131A1 Continuous process to obtain a crystalline monosaccharide  
The invention relates to a continuous process for obtaining a crystalline monosaccharide, comprising a continuous crystallization of the monosaccharide in a main crystallizer (10), wherein in the...
DE202011111124U1 Polymorph of a tetrasaccharide containing N-acetyllactosamine  
A polymorph of Galpβ1-4GlcNAcpβ1-3Galpβl-4Glc (LNnT) characterized in that it has X-ray powder diffraction reflections based on measurement using CuKa radiation, at a 2Θ angle of 20.32±0.20,...
DE202013012839U1 New polymorphs from LNnT  
A crystalline LNnT polymorph IV, characterized in that it shows X-ray powder diffraction reflections based on a measurement using CuKa radiation at 2Θ angles of 8.16 and 15.41, more preferably at...
DE202017007249U1 Separation of oligosaccharides from the fermentation broth  
A solid sialylated oligosaccharide, the solid sialylated oligosaccharide being a spray dried or crystalline acidic human milk oligosaccharide selected from 6'-sialylylactose (6'-SL),...
DE202017007248U1 Separation of oligosaccharides from the fermentation broth  
An N-acetylglucosamine-containing neutral human milk oligosaccharide selected from LNT, LNnT or Lacto-N-Triose II obtained by a process for separating an N-acetylglucosamine-containing neutral...
DE102018007478A1 Medicinal or nutritional supplements for the treatment and / or prophylaxis of joint diseases and / or inflammatory joint diseases  
Pharmaceutical or food supplements for the treatment and / or prophylaxis of diseases of the joints, especially arthrosis, which contain a collagen hydrolyzate in combination with free...
DE202013012829U1 Improving the stability and purity and increasing the bioavailability of human milk oligosaccharides or precursors or mixtures thereof  
A spray-dried oligosaccharide from human milk (HMO) or a spray-dried HMO mixture with improved stability after prolonged storage at temperatures above 25 ° C and produced by a process comprising...
DE202013012827U1 Improving the stability and purity and increasing the bioavailability of human milk oligosaccharides or precursors or mixtures thereof  
Spray-dried neutral oligosaccharide from human milk (HMO) or a spray-dried neutral HMO mixture with improved stability after prolonged storage at temperatures above 25 ° C., which is produced by a...
DE202014011399U1 Neutral human milk oligosaccharides (HMOs) from microbial fermentation  
A concentrate of a neutral human milk oligosaccharide (HMO) product containing a desired HMO in a concentration of ≥ 100 g / l and one or more impurities in an aqueous solution, the HMO product...
DE202015009782U1 Separation of 2'-O-fucosyllactose from fermentation broth  
Crystallized 2-O'-fucusyllactose (2'-FL) produced by a process comprising the following steps: i. culturing a genetically modified cell having a recombinant gene encoding a 1,2-fucosyltransferase...
DE202015009775U1 Separation of 2'-FL from a fermentation broth  
Crystallized 2-O'-fucusyllactose (2'-FL) produced by a process comprising the following steps: i. Culturing a genetically modified cell containing a recombinant gene coding for a...
DE102018116200A1 METHOD FOR PRODUCING A NUCLEOTIDE SUGAR  
In a process for producing a monosaccharide-1-nucleoside diphosphate, a monosaccharide, a monosaccharide-1-phosphate kinase, a nucleoside triphosphate sugar-1-phosphate nucleosidyl transferase, a...
DE102010034968B4 Polymerizable compounds and liquid-crystal media  
Liquid-crystalline medium which comprises one or more compounds selected from the compounds of the formulas IA-1 to IA-10contains wherein R1' to R5' each independently of one another hydrogen,...
DE102018201920A1 Liquid functionally improved isomalt  
The present invention relates to a liquid isomalt composition comprising 6-O-alpha-D-glucopyranosyl-D-sorbitol (1,6-GPS) and 1-O-alpha-D-glucopyranosyl-D-mannitol (1,1-GPM ) and the other...
DE102018201916A1 Solid functionally improved isomalt  
The present invention relates to a solid isomalt composition comprising 6-O-alpha-D-glucopyranosyl-D-sorbitol (1,6-GPS) and 1-O-alpha-D-glucopyranosyl-D-mannitol (1,1-GPM ) and the other...
DE69907119T3 Powdered sorbitol and its method of preparation  
Pulverulent sorbitol has a hygroscopicity value of less than 2, preferably less than 1, %, and specific surface area of at least 2, preferably 2.2, m<2>/g (according to the method BET). An...
DE102017010898A1 New inhibitors of shikimic acid pathway  
The present invention relates to novel inhibitors of the shikimic acid pathway (shikimate route), to pharmaceutical compositions containing these novel inhibitors, to processes for the preparation...
DE102017125888A1 New engineered T cell receptors and their use in immunotherapy  
The present invention relates to antigen-recognizing constructs against COL6A3 antigens. In particular, the invention provides novel engineered T cell receptor (TCR) based molecules which are...
DE102015219343B4 A method of processing seaweed-derived galactose using agarase  
Process for preparing galactose, the process comprising: treating a residue of red algae by steps, comprising saccharification of the red algae by hydrolysis with an acid and filtration of the red...
DE112017002818T5 Compound for use in an enzymatic reaction and mass spectrometry methods  
A compound used in the conventional enzymatic reactions and mass spectrometry methods must be changed in structure as a substrate compound, such as the length of an alkyl chain contained therein,...
DE102015214603B4 Phosphorus containing aminoglycoside salts  
Compound of Formula 1 wherein the aminoglycoside is selected from the group of aminoglycoside or aminoglycoside group-containing antibiotics, where y is selected from 0.1 to 20, where n is...
DE102017115966A1 Polypeptide molecule with improved dual specificity  
The present invention relates to a bispecific polypeptide molecule, comprising a first polypeptide chain and a second polypeptide chain, which provide a binding region, derived from a T cell...
DE112016005245T5 METHOD FOR THE FRACTIONATION OF LIGNOCELLULOSE-CONTAINING BIOMASS  
This invention aims to develop a process for fractionating lignocellulosic biomass by contacting lignocellulosic biomass with treating liquid in a closed system at a temperature not exceeding 200...
DE102017003004A1 Cationic polymers with D-fructose substituents  
The invention relates to novel cationic polymers which are D-fructose conjugated, whereby they are able to interact selectively with specific structural elements on cell surfaces. The task was to...
DE102017002810A1 Sialic acid derivatives with CC triple bond and their preparation  
Sialic acid derivatives containing a CC triple bond are described, processes for their preparation, conjugates prepared therefrom and pharmaceutical compositions containing them.
DE102017002252A1 Enzymatic process for the production of fructose  
The present invention relates to a process for the preparation of aqueous solutions of D-fructose from a di-, oligo- or polysaccharide. Current methods are based on the generation of D-glucose...
DE102007032799B4 Sugary metal complexes and their use  
Sugar-containing metal complexes of substituted polypyridines of general formula I.(L1n)(L2m)(L3O)(L4p)(L5q)M+/-.consisting of ligands L1 to L5, wherein at least one of these ligands L1 to L5 is a...
DE102006035020B4 Stabilization of NAD / NADH  
A test element for the determination of an analyte comprising (i) a coenzyme dependent enzyme or a substrate for such an enzyme and (ii) as a coenzyme a compound having the following general...
DE202015009594U1 New dimers of cytidine derivatives  
A cytidine derivative dimer having the following general formula (I), wherein: R 1 is a CC alkyl, CC-substituted alkyl, - (CH) -Ph or substituted - (CH) -Ph; in - (CH) -Ph, n = 0, 1, 2, 3 ~ 10 and...
DE102016225419A1 Olfactory signaling after overheating in technical facilities by pyrolysis of fragrance derivatives  
The present invention relates to a method for providing a technical device with a warning signal against heating and a kit with which the method can be carried out.
DE60130583T3 SMALL RNA MOLECULES TRANSFERRING RNA INTERFERENCE  
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we...
DE10113265B4 Use of a stabilized nucleic acid for the production of a protein  
The invention teaches the use of a linear nucleic acid stabilized against exonuclease degradation in a method of producing a protein encoded by a base sequence of the nucleic acid in a cell-free...
DE102016116121A1 Process for the epimerization of saccharides  
The invention relates to a process for the epimerization of saccharides by heating a saccharide dissolved in a solvent in the presence of a metal-containing catalyst, an aldose being contacted...
DE102016124844B3 DNA probes for in situ hybridization of chromosomes  
Kit, probe mixtures and probes for the detection of a chromosome aberration. A gene probe obtained by a method comprising the following steps: (a) examining genomic sections for sequence regions...
DE102011118022B4 Antibodies against the prostate-specific stem cell antigen and its use  
The invention relates to recombinant antibodies that bind to prostate-specific stem cell antigen (PSCA). The antibody according to the invention contains complementarity-determining regions (CDR)...
DE60017711T3 ANALOGUE OF NUCLEOSIDES AND OLIGONUCLEOTIDES  
The object of the present invention is to provide novel oligonucleotide analogues, which exhibit antisense or antigene activity having excellent stability, or exhibit excellent activity as a...
DE102007063902B3 Aptamers that bind to a target molecule involved in hemostasis  
Aptamer that binds to a target molecule involved in hemostasis, the aptamer being an aptamer that binds to activated protein C, the aptamer having a dissociation constant KD binds to activated...
DE102011018627B4 Modified nucleotides  
Connection with structure (I): or a salt, a conjugate base, a tautomer or a dissociated form thereof, wherein P1 is a phosphate group; P2 is a phosphate group; Nus is a nucleoside structural unit...
DE112012003416B4 Process for the preparation of 2- (4-methoxycarbonylpyrazol-1-yl) adenosine and 2- (4-ethoxycarbonylpyrazol-1-yl) adenosine  
A process for the preparation of 2- (4-methoxycarbonylpyrazol-1-yl) adenosine of the formula Ia and 2- (4-ethoxycarbonylpyrazol-1-yl) adenosine of the formula Ib by reaction of...