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DE102006053690A1 New anionic cyclopentadienyl-carbohydrate compounds useful in the preparation of metallocene-carbohydrate compound, which is useful to treat cancer  
Anionic cyclopentadienyl-carbohydrate compounds (I), are new. Anionic cyclopentadienyl-carbohydrate compounds of formula (I), are new. m : 0-10 (preferably 1); ER1 : OH, alkoxy, nucleo-base or...
DE102006053637A1 New fluorine-substituted 1,4-benzothiepine-1,1-dioxide, a process for their production, medicaments containing these compounds and their use  
The Invention relates to the compounds of formula I and physiologically acceptable Salts. The compounds are suitable for. B. as hypolipidemic agents.
DE102006053635A1 New substituted with benzyl 1,4-Benzothiepin-1,1-dioxide derivatives, processes for their preparation, pharmaceutical compositions containing them and their use  
The Invention relates to the compounds of formula I and physiologically acceptable Salts. The connection is suitable for. B. as hypolipidemic agents.
DE102006053385A1 Enterococcus faecalis and / or Enterococcus faecium antigen  
The This invention relates generally to the field of detection and prevention of infectious diseases caused by Enterococcus faecalis and / or Enterococcus faecium caused. In particular relates to...
DE102006035393A1 Prognostic markers for the classification of the three-year progessionsfreien survival of patients with colon cancer based on expression profiles of biological samples  
The Invention relates to the use of gene expression profiles for Predicting the three-year progression-free survival or recurrence of patients receiving colorectal cancer in UICC stage I or II was...
DE69936632T2 INHIBITING CYTOKINE PRODUCTION  
The invention provides a ds-DNA oligomer which has from 25 to 150 base pairs, preferably 25 to 50 base pairs, and comprises the palindrome-containing sequence (one strand only shown) of formula...
DE69838250T2 PREDICTION coronary artery disease  
Methods and assays are disclosed for predicting a patient's risk for an inflammatory disorder such as coronary artery disease or related vascular disorders. The methods comprise obtaining a...
DE69738028T2 METHOD AND APPARATUS FOR BULK TRANSPORT-SUPPORTED OPTICAL TESTS  
An optical assay device for the detection of an analyte of interest in a sample comprising a support containing channels, an optically functional layer positioned on the support such that the...
DE60130009T2 macrolides  
The invention relates to novel semi-synthetic macrolides of formula (I) having antibacterial activity. More particularly this invention relates to derivatives of 8a-aza-8a-homoerythromycin A, to...
DE202005021489U1 A composition as for the synthesis of compounds phosphitylated  
A method for preparing a phosphitylated compound comprising the step of:-reacting a hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I)...
DE202005021488U1 Mixture of an activator and an additive for preparing phosphitylated compounds  
A method for preparing a phosphitylated compound comprising the step of:-reacting a hydroxyl containing compound with a phosphitylating agent in the presence of an activator having the formula (I)...
DE69936877T2 STREPTOCOCCAL C5a PEPTIDASE VACCINE  
Novel vaccines for use against beta -hemolytic Streptococcus colonization or infection are disclosed. The vaccines contain an immunogenic amount of a variant of streptococcal C5a peptidase (SCP)....
DE69637148T2 Nucleic acid molecules, proteins and peptides, IN ANY WAY CONNECTED WITH COLON CELLS AND COLON CANCER CELLS  
This invention relates to isolated proteins and to peptides which are found on the surface of colon cells and colon cancer cells, as well as to nucleic acid molecules encoding said protein and...
DE69637036T2 amylase variants  
A variant of a parent alpha -amylase, which parent alpha -amylase (i) has an amino acid sequence selected from the amino acid sequences shown in SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, and SEQ...
DE69535560T2 ON STRENGTHENED BY VIRUS MEDIATED DNA TRANSFER  
A method to increase the efficiency of transduction of hematopoietic and other cells by retroviruses includes infecting the cells in the presence of fibronectin or fibronectin fragments. As can be...
DE69535543T2 ENZYMES, THE ABILITY OWN LINEAR ALPHA-1,4-glucans IN PLANTS, MUSHROOMS AND MICROORGANISMS TO synthesize, CODING DNA SEQUENCES  
DNA sequences coding for enzymes capable of facilitating the synthesis of linear □-1,4 glucans in plants, fungi and microorganisms. The invention relates to DNA sequences Coding for proteins...
DE69435010T2 METHODS AND MATERIALS FOR THE TREATMENT OF INDIVIDUALS, THE INFECTED WITH ARE intracellularly INFECTIOUS AGENTS  
PCT No. PCT/US94/04367 Sec. 371 Date Jul. 29, 1996 Sec. 102(e) Date Jul. 29, 1996 PCT Filed Apr. 20, 1994 PCT Pub. No. WO94/24267 PCT Pub. Date Oct. 27, 1994Recombinant polynucleotides are...
DE60318192T2 USE OF A2A adenosine receptor agonist AND ANTI-PATHOGENIC AGENTS CONTAINING COMBINATIONS FOR THE TREATMENT OF INFLAMMATORY DISEASES  
The present invention provides a therapeutic method for treating biological diseases that includes the administration of an effective amount of a suitable antibiotic agent, antifungal agent or...
DE60315164T2 PARTIAL AND FULL AGONISTS OF A1-adenosine receptors  
Disclosed are A1 adenosine receptor agonists of the formula: wherein: R1 is optionally substituted cycloalkyl, optionally substituted heterocyclyl, optionally substituted aryl, or optionally...
DE60129929T2 METHOD FOR PRODUCING FUNCTIONALIZED BETA- (1.3) -GLUCANDERIVATEN  
The present invention relates to a novel method of chemically preparing functionalized derivatives of beta-(1,3)-glucans, enabling obtaining oligosaccharides which are free or which comprise...
DE60129863T2 Hydroxy-substituted 2-azetidinones useful as hypocholesterolemic drugs  
please check closely-very confusing Hypocholesterolemic sugar-substituted 2-azetidinone compounds of the formula: are disclosed, as well as a method of lowering cholesterol by administering said...
DE60129809T2 IN VITRO EVOLUTION OF NUCLEIC AND ENCODED POLYPEPTIDES  
This invention relates to methods and reagents for selecting a desired protein or nucleic acid molecule by linking mRNA, with known or unknown sequences, to its translated protein to form a...
DE60129688T2 HUMAN BETA-1A SUBUNIT OF POTENTIAL-DEPENDENT SODIUM CHANNEL AND USES THEREOF  
DNAs encoding human voltage gated sodium channel beta1A subunit have been cloned and characterized. The recombinant protein is capable of forming biologically active protein. The cDNA's have been...
DE112004002408B4 A process for obtaining an enriched population of siRNA-expressing cells  
process for obtaining cells which are capable of inhibiting RNA expressing, said method comprising: introducing at least one nucleic acid in a cell, wherein the at least one nucleic acid in the...
DE69737992T2 GENETIC ABOLITION AND EXCHANGE  
A strategy for suppressing specifically or partially specifically an endogenous gene and introducing a replacement gene, said strategy comprising the steps of: 1. providing suppressing nucleic...
DE602004008085T2 Antisense Oligonucleotide FOR INHIBITING MELANOMA inhibitory activity (MIA)  
An antisense oligonucleotide selected from the group of the sequence 5′-TTG CAT AAA CCC AAG GAG-3′ (SEQ ID NO: 1) and modifications thereof a fragment having at least 8 nucleotides of the sequence...
DE60127162T2 Massive parallel method for decoding DNA and RNA  
This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue...
DE102006049821A1 New, well tolerated metal chelates, for use as radiodiagnostic, radiotherapeutic or NMR and X-ray diagnostic agents, contain chelator and perfluorinated polyethylene glycol residues  
New metal chelates (I) (optionally in salt form) contain (a) perfluorinated polyethylene glycol (PEG) residue(s), (b) chelator residue(s) and (c) at least one equivalent of metal(s) of atomic...
DE69737978T2 ALS 2F1 designated RECEPTOR PROTEIN  
2F1 polypeptides are provided, along with DNA sequences, expression vectors and transformed host cells useful in producing the polypeptides. Soluble 2F1 polypeptides find use in inhibiting...
DE69838097T2 INFECTIOUS CLONE FOR HUMAN INFLUENZA VIRUS PARA-TYPE  
A system for generating recombinant, human parainfluenza virus, particularly infectious, recombinant, human parainfluenza virus type 3 (HPIV-3) is provided. In one embodiment, the system comprises...
DE60315359T2 Pyridinium-Betain compounds and their use  
The present invention concerns Pyridinium-Betain compounds of the following general formula (A) R1 is H R2 is a chemical group formed by a sugar pentose or hexose ring, substituted at C5 or C6,...
DE3752172T3 Nucleic acid probes for the detection and / or quantitation of non-viral organisms  
A method for preparing probes, as well as several probes for use in qualitative or quantitative hybridization assays are disclosed. The method comprises constructing an oligonucleotide that is...
DE10226203B4 Condensed palatinose, processes for their preparation and their use  
The invention relates to a novel palatinose condensation product which is obtained by condensing the disaccharide palatinose in a molten mass of palatinose, water and an organic acid.
DE102007016151A1 coated implant  
implant with a coating, wherein the implant is an amino-functionalized Parylene, an oligonucleotide and / or an oligopeptide comprising, which have a specific binding affinity for CD 34-positive...
DE102006042891A1 Breaking down of poly-, oligo-, disaccharide or its derivatives, useful as raw material e.g. in textile industry, comprises dissolving the derivatives in an ionic liquid and treating the mixture at an elevated temperature  
Method for breaking down of poly-, oligo-, disaccharide (I) or its derivative comprises dissolving (I) in an ionic liquid and treating the mixture at an elevated temperature, optionally in the...
DE102006042890A1 Silylating poly-, oligo-, disaccharides derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent  
Silylating poly-, oligo-, disaccharides or their derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent. An...
DE69838073T2 Recombinant nodavirus COMPOSITIONS AND METHODS  
Recombinant nodavirus related compositions are disclosed. These compositions include chimeric proteins in which a nodavirus capsid protein is present together with a heterologous peptide segment....
DE60035499T2 IDENTIFICATION OF MATERIAL FROM THE CHANNEL BREAST MILK  
Methods and systems for identifying material from a breast duct using one or more markers that can be identified in ductal fluid retrieved from the breast are provided.
DE102006037786A1 Nucleosides, containing these drugs and their use  
The Invention relates to specific nucleosides, and drugs which these nucleosides contained. Furthermore, the invention relates to the Use of such nucleosides for the preparation of a medicament,...
DE69737889T2 CALCIUM-ACTIVATED POTASSIUM CHANNELS WITH LOW AND MIDDLE CONDUCTIVITY AND USES THEREOF.  
This invention relates to small and intermediate conductance, calcium-activated potassium channel proteins. More specifically, the invention relates to compositions and methods for making and...
DE69334150T2 MUTANT steroid hormone receptors, METHODS FOR THEIR USE AND MOLECULAR SWITCH FOR GENE THERAPY  
The present invention provides mutant proteins of steroid hormone receptors. These mutant proteins are useful in methods of distinguishing a steroid hormone receptor antagonist from a steroid...
DE60221004T2 Immunostimulant OLIGODEOXYRIBONUKLEIN MOLECULES  
Described is a method for stabilisation of nucleic acids by conctacting the nucleic acids with a polycationic polymer.
DE60035355T2 IMMUNE REINFORCING LINKS  
The invention provides an immunopotentiating composition and to a composition accelerating the production of interferon- gamma , both comprising lactosuclose as an active ingredient. In...
DE69936453T2 FOR A G protein-coupled receptor, AT THE EMPFINDUNGSTRANSDUKTION INVOLVED, CODING NUCLEIC  
The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids...
DE69838651T2 Erythromycin derivatives  
This application relates to compounds of the formula and pharmaceutically acceptable salts thereof, wherein R, R 3 , R 4 and X are as defined herein, to processes for the preparation of these...
DE69737814T2 CONDENSED SOLUBLE TYPE-I-RECEPTORS FOR TUMOR NECROSIS-FACTOR  
Disclosed are novel proteins, referred to as tumor necrosis factor binding proteins, that modulate the activity of tumor necrosis factor. Also disclosed are processes for obtaining the tumor...
DE69637153T2 IMPROVEMENTS IN OR RELATING TO PFANZENSTÄRKEVERBINDUNGEN  
Disclosed is a nucleotide sequence encoding an effective portion of a class A starch branching enzyme (SBE) obtainable from potato plants, or a functional equivalent thereof, together with, inter...
DE69434988T2 Tumor necrosis FACTOR GAMMA  
A human TNF-gamma polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for...
DE69434926T2 HUMAN tissue inhibitor of metalloproteinase-4  
A human tissue inhibitor of metalloproteinases-4 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques. Also disclosed are...
DE68929551T2 Human DNase  
DNA isolates coding for human DNase and methods of obtaining such DNA are provided, together with expression systems for recombinant production of human DNase useful in therapeutic or diagnostic...