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DE60036700T2 Antiproliferative activity of G-RICH Oligonucleotides AND METHOD IN ORDER TO BE BOUND BY NUKLEOTIN USE  
The present invention provides a method for inhibiting the proliferation of malignant and/or hyperplastic cells in a subject by administering to the subject a therapeutically effective amount of a...
DE102007027201A1 Conjugates useful for chemotherapy or positron emission tomography comprising a platinum complex and a glucose compound  
Conjugates comprising a chemotherapy-active platinum complex and a glucose compound, optionally linked together via a spacer, are new. ACTIVITY : Cytostatic. No biological data given. MECHANISM OF...
DE69937352T2 MAISZELLULOSESYNTHASEN AND USES THEREOF  
The invention provides isolated cellulose synthase nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering cellulose synthase...
DE69738206T2 DNA diagnostics by mass spectrometry  
Fast and highly accurate mass spectrometry-based processes for detecting a particular nucleic acid sequence in a biological sample are provided. Depending on the sequence to be detected, the...
DE69738197T2 AZOLOTRIAZINE AND PYRIMIDINES  
The invention relates to corticotropin releasing factor (CRF) antagonists of formula (I) or (II) and their use in treating anxiety, depression, and other psychiatric, neurological disorders as...
DE69132581T3 IMPROVED CHIMERIC TOXINS  
A chimeric toxin comprising protein fragments joined together by peptide bonds, the chimeric toxin comprising, in sequential order, beginning at the amino terminal end of the chimeric toxin, (a)...
DE60316853T2 A process for the recovery of sucralose of high purity and high yield  
This invention relates to a method of obtaining sucralose from a feed mixture comprising 6-O-acyl-4,1',6'- trichloro-4,1',6'-trideoxygalactosucrose, other chlorinated sucrose byproducts, and...
DE60130669T2 POLYSACCHARIDES having an antithrombotic action, WITH BIOTIN OR A BIOTIN DERIVATIVE COVALENTLY BOUND  
The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing...
DE102007002386A1 Pharmaceutically active compounds  
The present invention relates to pharmaceutically active compounds from an isoflavone or isoflavone glycoside and covalently with this connected, an amino acid, a peptide or peptide derivative...
DE69535601T2 Nucleotides SEQUENCES FROM RETRO VIRUS ANTIGENS HIV-I GROUP (OR SUB-GROUP) O  
A protein (I) of HIV-1 (sub) group O (or natural or synthetic (poly)peptides contg. at least part of (I)) that can be recognised by antibodies isolated from the serum obtained after infection with...
DE69937198T2 TREATMENT OF ALZHEIMER'S DISEASE BY INCREASING THE cytidine MIRROR IN VIVO  
A preparation for use in the prevention and/or treatment of neurological disorders, said preparation comprising (a) uridine or a uridine source and (b) choline, a choline precursor, a choline salt...
DE69334174T2 Preparation of carboxylic acid-sugar  
A process for producing a saccharide carboxylic acid or a salt thereof is characterised in that a microorganism belonging to the genus Pseudogluconobacter and capable of oxidizing a hydroxymethyl...
DE60316389T2 Using hederagenin 3-OAL rhamnopyranosyl ((1-> 2) - (ß-D-glucopyranosyl (1-> 4)) - aL-arabinopyranoside or this containing extract from Pulsatillae radix as a therapeutic agent for solid tumors  
This invention relates to a use of hederagenin 3-O- alpha -L-rhamnopyranosyl((1->2)-Ä beta -D-glucopyranosyl(1->4)Ü- alpha -L-arabinopyranoside or a Pulsatillae radix extract containing the same...
DE602004009128T2 Cosmetic use of new desquamating agents  
Composition for application to the skin or scalp comprises a 2-oxacycloalkyl malonic acid derivative (I). Composition for application to the skin or scalp comprises a 2-oxacycloalkyl malonic acid...
DE60130804T2 ANTAGONISTIC ANTIBODY PRO842  
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
DE3588254T2 GAG antigen and its use for the detection of LAV infection, as well as immunogenic compositions  
Purified material (I) contg. the polypeptide back bone of a glycoprotein of molecular wt. about 110,000, or antigen of lower molecular wt. derived from it, is new. (I) is recognised by sera of...
DE69738145T2 Illudin analogs used as an antitumor agent  
The present invention provides illudin analogs of general formula (I) where R1 is (CH2)n -X-Y or H; n is 0 to 4; X is O or S or N or absent; and Y is an optionally substituted (C1 - C8)alkyl,...
DE69535540T2 COMPOSITION CONTAINING NUCLEIC AND CATIONIC POLYMERS, PREPARATION AND USE  
PCT No. PCT/FR95/00914 Sec. 371 Date Feb. 28, 1997 Sec. 102(e) Date Feb. 28, 1997 PCT Filed Jul. 7, 1995 PCT Pub. No. WO96/02655 PCT Pub. Date Feb. 1, 1996Compositions containing one or more...
DE60315723T2 Production of polyketides and other natural products  
The present invention relates to production of polyketides and other natural products and to libraries of compounds and individual novel compounds. One important area is the isolation and...
DE60036490T2 COMPOSITION FOR THE TREATMENT OF PROSTATE CANCER  
A method of treating prostate cancer in a living mammal includes local administration of a composition that includes a therapeutically effective concentration of collagenase. In one embodiment, a...
DE10085149B4 A process for preparing acarbose with high purity  
Disclosed herein is a process for preparing highly pure acarbose of formula (I) useful as medicine for the treatment of diabetes. The disclosed process comprises prepurifying an...
DE69937108T2 Compounds and methods for the detection of biomolecules  
Methods are described for synthesizing compounds useful for detecting nucleic acids, and in particular, the hybridization of nucleic acids. Photocleavable agents are described, including but not...
DE69838651T9 Erythromycin derivatives  
This application relates to compounds of the formula and pharmaceutically acceptable salts thereof, wherein R, R 3 , R 4 and X are as defined herein, to processes for the preparation of these...
DE69838449T2 Aminooxy-modified oligonucleotides  
Nucleotide compositions containing aminooxy moieties are provided. In accordance with preferred embodiments, oligonucleotides and oligonucleotide analogs are provided which are specifically...
DE69435030T2 Method for detecting a DNA target molecule  
A means for cleaving a nucleic acid cleavage structure in a site-specific manner is disclosed. A cleaving enzyme having 5' nuclease activity without interfering nucleic acid synthetic ability is...
DE60316221T2 Glucose derivative of vitamin F, compositions containing it, uses, and methods of manufacture  
O-Acylated derivatives of glucose that may be obtained by partial or total esterification of vitamin F with glucose. O-Acylated derivatives of glucose that may be obtained by partial or total...
DE60222167T2 GAMMA-glutamylcysteine ​​PRODUCING YEAST  
A yeast which harbors a mutant glutathione synthetase having one or both of mutations selected from the group consisting of a mutation to replace a threonine residue at the position 47 with an...
DE60130583T2 SMALL RNA MOLECULES THAT RNA INTERFERENCE VERMITTELN  
Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we...
DE60036395T2 ENZYMES OF THE lysosomes LOOKING WAY  
The present invention provides nucleotide and amino sequences of the lysosomal targeting pathway enzyme GlcNAc-phosphotransferase, methods of producing and methods of purifying this enzyme.
DE102006059095A1 Microarray for detecting viruses is divided into fields, each bearing a nucleic acid probe capable of detecting a specific herpes virus  
Microarray for detecting viruses is divided into fields, each bearing a nucleic acid probe capable of detecting a specific virus, namely a herpes simplex virus probe, a varicella zoster virus...
DE69936781T2 KVLQT1 - ASSOCIATED WITH 'LONG QT SYNDROME'  
The genomic structure including the sequence of the intron/exon junctions is disclosed for KVLQT1 and KCNE1 which are genes associated with long QT syndrome. Additional sequence data for the two...
DE69535561T2 Nucleotide and amino acid Sequences gB, gC AND gD OF HERPESVIRUS OF DOG AND USES THEREOF  
Disclosed and claimed are nucleotides for genes encoding the canine herpesvirus (CHV) gB, gC and gD homologues. These genes encode polypeptides of 879, 459 and 345 amino acids, respectively, which...
DE60316298T2 INCREASING BIOAVAILABILITY / bio-effectiveness BY Cuminum cyminum AND ITS EXTRACTS AND FRACTIONS  
The invention relates to the isolation and preparation of an active fraction from plant Cuminum cyminum, its further purification and standardization as chemically defined entity (ies) with their...
DE60315950T2 Process for the preparation of xylooligosaccharides  
A process for manufacturing xyloligosaccharides comprises: steaming a corncob meal under conditions of a temperature of 150 to 250 DEG C and a pressure of 20 to 29 Mpa; filtering the steamed...
DE60222137T2 SUGAR DERIVATIVES OF hydromorphone, dihydromorphine, AND dihydroisomorphine, COMPOSITIONS THEREOF AND THEIR USE FOR THE PREVENTION AND TREATMENT OF PAIN  
Glucoside and glucuronide derivatives of hydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or...
DE69936977T2 BY polynucleic OF REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS OF PIG CODED PROTEIN  
The present invention provides a purified preparation containing, for example, at least one polypeptide selected from the group consisting of proteins encoded by one or more open reading frames...
DE69535590T2 FOR bradykinin B1 RECEPTOR CODING DNA  
DNAs encoding bradykinin B1 receptors from mammalian cells have been cloned and characterized. The recombinant receptor is capable of forming receptors which bind des-Arg10 kallidin and other...
DE602005002475T2 METHOD FOR PREPARING telithromycin  
The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts Formula I The novel compounds (i)...
DE69838338T2 USE OF antimycotica FOR TOPICAL TREATMENT OF MUSHROOM INDUCED INFLAMMATION MUCOSA  
This invention relates to the use of an antifungal agent in the manufacture of a medicament for treating asthma
DE69535587T2 RECOMBINANT ALLERGEN, ITS FRAGMENTS AND THAT CORRESPONDING DNA MOLECULES, VECTORS, AND THIS DNA MOLECULES CONTAINING FARMERS, AND DIGNOSTISCHE AND THERAPEUTIC USES SAID ALLERGENS AND FRAGMENTS  
A recombinant DNA molecule comprising a nucleotide sequence (I) which codes for a polypeptide displaying the antigenicity of one, two or more of the Phl p I epitope clones (28, 34, 41, 42, 43, 45,...
DE60315842T2 USE OF hesperidin OR ONE OF ITS DERIVATIVES FOR THE PREPARATION OF A MEDICAMENT TO STIMULATE BONE FORMATION  
The invention relates to the use of the compound hesperidin or of one of its derivatives for the manufacture of a composition designed to stimulate bone formation and/or inhibit bone resorption in...
DE60315545T2 A process for purifying protected 2'-Deoxycytidine  
A protected 2'-deoxycytidine is purified by precipitating the protected 2'-deoxycytidine represented by general formula (3) in the form of a hydrated crystal from a solution containing the...
DE602004008528T2 Means and methods for diagnosis and treatment of affective disorders  
The present invention relates to nucleic acid molecules, preferably genomic sequences, encoding an ATP-gated ion channel P2X7R which contain a mutation in the 5'UTR or 3'UTR regions, a mutation in...
DE102006054233A1 Silylating poly-, oligo-, disaccharides derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent  
Silylating poly-, oligo-, disaccharides or their derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent. An...
DE102006054213A1 Homogeneous phase acetalation of oligo- or polysaccharide, e.g. for production of acid-crosslinkable cellulose acetals, by reaction with vinyl ether in solution in ionic liquid  
Acetalation of di-, oligo- or polysaccharides (or their derivatives) (I) is carried out by dissolving (I) in at least one ionic liquid (II) and reacting with a vinyl ether (III). Independent...
DE102006054202A1 Alleles of oxyR gene from corynebacteria  
The Invention relates to mutants and alleles of the gene of coryneform oxyR Bacteria coding for Variants of the OxyR-transcriptional regulator, and methods for preparing of amino acids by using...
DE69936927T2 Polyspecific BINDING MOLECULES AND THEIR USE  
The present invention relates to polyspecific binding molecules and particularly single-chain polyspecific binding molecules that include at least one single-chain T-cell receptor (sc-TCR)...
DE69838298T2 CONTROL OF IMMUNE RESPONSES BY REGULATING ACTIVITY glycosyltransferases  
The invention provides methods for inhibiting immune responses by inhibiting the biosynthesis of the sialyl galactosides that are involved in immune responses. In particular, B lymphocyte-mediated...
DE69637229T2 Lipidation hydrophilic molecules  
The invention provides uses of lipid-containing moieties in the manufacture of compounds for delivery of sulfhydryl group-containing compounds into mammalian cells. The sulfhydryl group-containing...
DE69535584T2 Replicationsfähiger herpes simplex virus that mediates the destruction of neoplastic cells  
A method for killing malignant brain tumor cells in vivo entails providing replication competent herpes simplex virus vectors to tumor cells. A replication competent herpes simplex virus vector,...