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DE69233402T3 NEW cytokines  
There is disclosed an isolated antibody immunoreactive with CD40-L or a CD40-L immunogen.
DE60038610T2 NEW CRYSTALLINE FORMS OF A macrolide antibiotic  
Novel crystalline forms of a compound of Formula 1 are disclosed:Also disclosed are pharmaceutical compositions comprising these forms, and methods of their preparation and use.
DE102007062962A1 New surface protein mutant of hepatitis B virus HBV surface antigen (HBsAg)  
The invention relates to sequences of a new mutant or variant of the hepatitis B surface antigen (HBsAg) and methods, these genomic and protein variant and antibodies directed against them from...
DE69334209T2 PROTEIN AN INDUCIBLE resistance to glycopeptides CAUSED, PARTICULARLY IN GRAM NEGATIVE BACTERIA  
The protein VanB of formula (I) (in Fig.) is new. (I) is implicated in Gram positive bacteria, in resistance to glycopeptides, partic. vancomycin (II), this resistance being inducible by (II) but...
DE60320552T2 FATTY ACID ESTERS of ethoxylated alkyl glucosides  
A mixture of fatty acid esters of ethoxylated alkylglucosides of formula I is useful as a refatting agent in cosmetic formulations.
DE69938507T2 Fragment of "connective tissue growth FACTOR" (CTGF)  
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis...
DE69938567T2 METHOD FOR MARKING NUCLEIC  
The present invention relates to a process of fragmenting and labeling a synthetic or natural nucleic acid, comprising the steps of: providing a mixture containing a nucleic acid, a labeling agent...
DE60133467T2 MODIFIED SERUM ALBUMIN WITH REDUCED AFFINITY FOR NICKEL AND COPPER  
A modified serum albumin is provided which has been modified in the n-terminal region or binding region VI, such as through a truncation of at least three amino acids at the n-terminal end, so...
DE69738637T2 Leptin receptor DB, THE RECEPTOR CODING NUCLEIC AND APPLICATIONS THEREOF  
The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes....
DE60320302T2 METHOD FOR IDENTIFYING MODULATORS OF human orexin-2 RECEPTOR  
The present invention provides a new method for identifying modulators of human orexin-2 receptor without utilizing recombinantly produced nucleic acid molecules encoding human orexin receptor...
DE69738631T2 Endoglucanase from Thermotoga  
A thermostable glycosidase enzymes derived from various thermococcus, staphylothermus and pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and can...
DE602004012874T2 Avermectins and avermectin monosaccharides SUBSTITUTED IN THE 4'AND 4 '' - POSITION WITH PESTICIDES PROPERTIES  
Described is a compound of the formula (I) wherein the bond between carbon atoms 22 and 23 is a single or double bond; m is 0 or 1; R1, is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and either...
DE602004012840T2 4 '' - OR 4'-SUBSTITUTED avermectin and AVERMECTINMONOSACCHARIDDERIVATE WITH PESTICIDES PROPERTIES  
Disclosed are compounds of the formulain which n is 0 or 1; X-Y is -CH-CH- or -CH2-CH2-; Z is -C(-O)-, -C(-S)- or -SO2-; R1 is C1-C12alkyl, C3-C8cycloalkyl or C2-C12alkenyl; and R2 is R3-Z-,...
DE69738630T2 Human cancer antigen of the tyrosinase-like protein 1, and genes encoding for it  
The present invention discloses that the normal melanogenic gene, gp75 gene, encodes a gene product, a 24 amino acid peptide of ORF3, which is processed to an antigenic cancer peptide recognized...
DE69738586T2 HIGH EXPRESSION OF PROTEIN RATE  
The invention features a synthetic gene encoding a protein normally expressed in a mammalian cell wherein at least one non-preferred or less preferred codon in the natural gene encoding the...
DE102007052119A1 New coumermycin A1-derivative, useful as biologically active substance and as antibiotics or cytostatics, and for preventing diseases caused by bacteria or tumor  
Coumermycin A1-derivative (I), is new. Coumermycin A1-derivative of formula (I), is new. R1, R2 : CH 3, halo or H, preferably H, F, Cl, Br or I, where both R1, R2 are not simultaneously CH 3. An...
DE69738603T2 Method for generating libraries of complete cDNAs  
Disclosed is a method for making full-length cDNA libraries, which is for making libraries of cDNAs having lengths corresponding to full lengths of mRNAs and comprises the following steps of;...
DE10128250B4 Glykolipidderivate new, processes for their preparation and compositions comprising them  
The present invention is a compound of general formula (I) or a pharmaceutically acceptable salt of,wherein W represents carbon chain from 9 to 17 which containing double bond or hydroxy group...
DE69623473T3 Recombinant hexose OXIDASE, PROCESS FOR THEIR PRODUCTION AND USE  
A method of producing hexose oxidase by recombinant DNA technology, recombinant hexose oxidase and the use of such enzyme, in particular in the manufacturing of food products such as doughs and...
DE102008050273A1 Apparatus and method for synthesizing a biopolymer and method for recovering a reagent for synthesizing a biopolymer  
A Apparatus for synthesizing a biopolymer has a reaction chamber (100), an outlet (410b) connected to the reaction chamber (100) is connected, a plurality of recovery tanks (461A, 461C, 461g,...
DE69809362T3 Specially shaped maltitol, containing these crystalline compositions and methods for their preparation  
New crystalline maltitol forms containing: (a) bipyramidal; (b )prismatic; or (c) a mixture of bipyramidal and prismatic crystals. The bipyramidal-form crystals comprise regular octahedra of...
DE69637472T2 Recombinant vesiculoviruses AND THEIR USE  
The invention provides recombinant replicable vesiculoviruses. The invention provides a method which, for the first time, successfully allows the production and recovery of replicable...
DE202008016372U1 Vitamin containing composition  
vitamin containing composition, particularly suitable for nutritional accounted supplement food in inner ear disorders, said composition comprising as an effective Constituents substances...
DE19520398B4 Magnetic pigment  
New prods. are (a) magnetic particles with an external glass surface that is nonporous or has pores with a dia. below 10 nm and (b) ferromagnetic particles with a glass surface.
DE69532958T2 CONJUGATES MADE OF METAL COMPLEX AND Oligonucleotides  
This invention relates to chemically modified oligonucleotide conjugates that contain a complexing agent or complex that is bound by a connecting component to the oligonucleotides. In this case,...
DE60038495T2 Oligonucleotide N3 '→ P5' thiophosphoramidates: THEIR SYNTHESIS AND USE  
Oligonucleotides with a novel sugar-phosphate backbone containing at least one internucleoside 3'-NHP(O)(S-)O-5' linkage, and methods of synthesizing and using the inventive oligonucleotides are...
DE60038449T2 MEDICINES SUBSTANCES WITH TWO LINKED COVALENTLY SUBSTANCES (SODIUM CHANNEL BLOCKER / P2Y2 RECEPTOR AGONIST) FOR THE TREATMENT OF MUCOUS MEMBRANES  
Compounds of the general formula P1-L-P2; wherein "P1" is a pyrazinoylguanidine sodium channel blocker, "L" is a linking group, and "P2" is either (i) a pyrazinoylguanidine sodium channel blocker...
DE102008012336A1 Separation of charged absolute electrostatic repulsion / hydrophilic interaction  
In one aspect includes a method of conducting an electrostatic repulsion / hydrophilic interaction chromatography to a protein, a peptide or an amino acid, the Providing a column with an...
DE102007041476A1 Aptamers that bind to a party to the hemostasis target molecule  
The Invention relates to an aptamer that binds to an haemostasis participating target molecule binds with the aptamer an aptamer is that binds to activated protein C, wherein the aptamer with a...
DE60225652T2 Oligonukleotidmarkierungsreagenzien on the basis of acyclic nucleosides, and their derivatized conjugates  
The invention relates to a labeling reactant of formula (I) useful for labeling an oligonucleotide wherein: R is a temporary protecting group. A is either a phosphorylating moiety or a solid...
DE60133550T2 Last dispersible colloidal calixarenes systems in the form of nanoparticles  
A water dispersible colloidal system in the form of generally spherical matrix type particles and of sizes typically in the range of from 50 to 500 nm, called nanoparticles, and a process for the...
DE102007044765A1 A process for the liquid phase synthesis of a polymer  
The Invention relates to a process for the liquid phase synthesis of a n monomers formed polymer.
DE602004012404T2 PROCESS FOR THE SELECTIVE INHIBITION OF HUMAN N-MYC GENE IN N-MYC EXPRESSING TUMORS THROUGH antisense and sense peptidonucleic (PNA)  
The present invention refers to sense and antisense peptide nucleic acids (PNAs). The present invention further refers to the use of said PNAs for preparing drugs for treating genetic diseases.
DE69535719T2 FAS ANTIGEN BINDING LIGAND  
Novel human and murine proteins designated Fas ligand (Fas-L) bind to the cell surface protein known as Fas antigen. DNA sequences, expression vectors and transformed host cells useful in...
DE60133011T2 METHOD FOR PRODUCING disaccharide and trisaccharide C6-C12 FATTY ACID ESTERS WITH HIGH ALPHA CONTENT AND MATERIALS THEREOF  
The present invention provides disaccharide and trisaccharide C6 to C12 mixed fatty acid esters having a high alpha content. Yet still further, the invention provides chemical processes for the...
DE202007018725U1 Oligonucleotide probes and containing these diagnostic kits for the determination of linezolid resistance  
Oligonucleotide probe hybridizing specifically with ribosomal RNA of microorganisms, the specific ribosomal to an under hybridization conditions RNA of the microorganism, the induced by a...
DE60225299T2 Nucleophilic Fluorination TO SOLID PHASE  
The present invention relates to novel solid-phase processes for the production of radiolabelled tracers, in particular for the production of <18>F-labelled compounds which may be suitable for use...
DE602005005240T2 4'-C-substituted 2-halo adenosine derivatives  
The present invention provides a 4'-C-substituted-2-haloadenosine derivative represented by the following formula ÄIÜ, ÄIIÜ, or ÄIIIÜ: (wherein X represents a halogen atom, R<1> represents an...
DE60133102T2 FISCHIMPSTOFF AGAINST Piscirickettsia salmonis  
The present invention relates to a fish vaccine. More specifically the invention relates to a vaccine to protect salmon against infection by Piscirickettsia salmonis. The invention is based on or...
DE60038248T2 MONO- AND disaccharide  
The present invention relates to a novel family of monosaccharide derivatives and disaccharide derivatives and to methods of preparation thereof. The novel mono- and disaccharide derivatives have...
DE60038220T2 Chimeric antisense oligonucleotides AND ZELLTRANSFEKTIONS COMPOSITIONS THEREOF  
Chimeric oligonucleotide of the formula 5'-W-X<1>-Y-X<2>-Z-3', where W represents a 5'-O-alkyl nucleotide, each of X<1> and X<2> represented a block of seven to twelve phosphodiester-linked...
DE102005029811B4 Oligonucleotide arrays, methods for their use, and their use  
Oligonucleotide arrangements are disclosed which, in each case, have at least two oligonucleotide sequences linked via at least one spacer. A process is disclosed using the oligonucleotide...
DE60225157T2 DEVICE THAT THE RELEASE of nucleotides DURING A REACTION PILOTS  
The methods, compositions and apparatus disclosed herein are of use for nucleic acid sequence determination. The methods involve isolation of one or more nucleic acid template molecules and...
DE60225141T2 METHOD FOR INCREASING THE IN VIVO EFFICACY OF Oligonucleotides AND IGNITION RESISTANCE IN MAMMALS  
The invention relates to the use of nucleotide substitutes for increasing the in vivo efficacy of nucleic acid molecules and also for inhibiting inflammation in mammals. More particularly, the...
DE602004011674T2 PROMOTER MOLECULES FOR USE IN PLANTS  
The present invention relates to polynucleotide molecules for regulating gene expression in plants. In particular, the invention relates to DNA sequences of the rice (Oryza sativa cv Nipponbare)...
DE60132924T2 COMPOSITIONS AND METHODS FOR THE DETECTION OF HUMAN IMMUNODEFICIENCY VIRUS 2 (HIV-2)  
Compositions and methods for synthesizing and detecting HIV-2 specific amplicons. Particularly described are oligonucleotides that are useful as hybridization probes, and amplification primers...
DE60132986T2 COMPOUNDS AND METHODS FOR REDUCING CHOLESTEROL MIRROR WITHOUT INDUCTION hypertriglyceridemia  
This invention provides methods of lowering cholesterol, delaying the onset of atherosclerosis, or treating atherosclerosis in a mammal without inducing hypertriglyceridemia. These methods involve...
DE102005011003B9 Method and means for the differential diagnosis of thyroid tumors  
process for the differential diagnosis of thyroid tumors to differentiate of benign tumors to malicious Tumors wherein: 1) RNA is isolated from a tissue sample of the thyroid gland, 2.) in the...
DE69435075T2 IMMUNOGENIC CHIMERA COMPRISING nucleic acid sequences SIGNAL SEQUENCE PEPTIDES endoplasmic reticulum AND AT LEAST ANOTHER PEPTIDE CODING, THEIR USE IN VACCINES AND FOR THE TREATMENT OF DISEASES  
Immunogenic chimeric proteins comprising an endoplasmic reticulum signal sequence and at least one other peptide are disclosed. The invention relates to the design of vaccinia virus constructs...
DE60132596T2 NUCLEIC BINDING COMPOUNDS PYRAZOLOi3,4-D pyrimidine analogue of purine-2,6-DIAMIN AND THEIR USE  
The present invention is in the field of nucleic acid binding compounds comprising 7-substituted 7-deaza-8aza-2,6-diamino-purine bases, compounds useful for the preparation of such compounds,...