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DE102007053947B4 A process for the synthesis of sucrose-6-acetic acid ester  
A method for the synthesis of sucrose-6-acetic acid esters, comprising the steps of: (A) the addition of sucrose in a polar aprotic solvent and stirring the solvent to dissolve it and to produce a...
DE102004062386B4 Monacolin K biosynthesis genes  
Isolated DNA molecules (a) have any of the sequences (all reproduced) (1; 226 nucleotides (nt)), a lovastatin probe; (2; 9818 nt), mkA; (3; 8081 nt), mkB; (4; 1717 nt), mkC; (5; 792 nt), mkD; (6;...
DE112008001507T5 New hybrid compounds of nucleobases and organic redox molecules and their use  
Hybrid combination with i) a unit of a purine or pyrimidine nucleobase or a Dervivat thereof, ii) a redox active moiety and iii) a spacer moiety connecting the Nukleobaseeinheit with the redox...
DE69825128T3 USE OF AZITHROMYCIN FOR TOPICAL TREATMENT OF EYE INFECTIONS  
The invention relates to topical compositions containng azithromycin for the treatment of ocular infections.
DE102008053549A1 Glucosylglycerol containing composition  
The invention relates to a composition comprising 20-80 wt .-% wt .-% glucosylglycerol and 0.5-20 one or more mono- and / or disaccharides. Surprisingly, it has been found that a particular...
DE102008053284A1 Stabilizer, useful for stabilizing heparin-binding growth factors and for manufacturing medicament e.g. for wound healing and bone regeneration, comprises a compound having an oligophosphate group  
Stabilizer comprises a compound having at least one oligophosphate group. Independent claims are also included for: (1) stabilizing heparin-binding growth factors, comprising contacting the...
DE102008053607A1 Solubilizing agent for metal ions  
The invention relates to a solubilizing agent for metal ions, and sparingly soluble metal compounds containing, as solubilizing agent, an oxidation product of starch, methods for solubilizing...
DE202009017108U1 Monoclonal antibody to Microcephalin (MCPH1)  
A monoclonal antibody or fragment thereof, characterized in that it specifically binds to Microcephalin (MCHP1) and recognizes an epitope which is located in the area of ​​amino acids 1 to 267 of...
DE102005031755B9 Salmonella spp. binding peptides, nucleic acids coding therefor, their uses, and methods and kits for the enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE19943491B4 Improved compressed  
A process for producing a compressed product of isomaltulose, isomalt, or isomalt variants, wherein the isomalt variants 1,6-GPS and 1,1-GPM-containing mixtures are that through to deviate from...
DE69029370C5 Erythropoietin isoforms  
Continuation in part of U.S. application no. 421,444 filed 13 October 1989. Erythropoietin isoforms claimed are produced by expression of exogenous DNA in a non-human eukaryotic host cell. They...
DE102008044914A1 A process for preparing nucleoside conjugates phosphatverbrückter  
The invention relates to a process for preparing phosphatverbrückter nucleoside conjugates. In the method, a nucleophile is dissolved in a non-aqueous solvent, and dried and then added a...
DE19854973B4 A method for purifying nucleic acids  
Preparation comprising particles having a glass surface, which contains more than 75th% of these particles have a particle size between 0.5 and 15 microns have characterized in that the glass...
DE102008035299A1 Conjugate, particularly bromovinyl-deoxyuridine for manufacture medicament for inhibiting or suppressing metastasis including distant metastases in cytostatic treatment, includes heat shock protein and nucleoside  
A conjugate includes a heat shock protein 27 (Hsp 27) and a nucleoside. The conjugate has a general formula (I), where the conjugate is made of heat shock protein 27 (Hsp 27) and nucleoside. R...
DE10237691B4 A method for detecting single nucleotide polymorphisms (SNP) in genes of drug metabolism and test kit for performing the method  
A method for the detection of single nucleotide polymorphisms in the cytochrome P450 genes, characterized in that a) gene segments of human CYP2 genes from a sample with the amplification primers...
DE10004815B4 Human intestinal sodium phosphate cotransporter  
Npt2B polypeptide (I) having a 688 amino acid sequence (1), reproduced in the specification, is new. Independent claims are also included for the following: (1) Npt2B polypeptide (I') at least 90%...
DE69526973T3 SEQUENCES OF HEPATITIS C VIRUS GENOTYPE 7 AND THEIR USE AS PREVENTIVE, THERAPEUTIC AND DIAGNOSTIC AGENTS  
The present invention relates to HCV type 10 sequences. These HCV sequences are useful to diagnose the presence of HCV in a biological sample. Moreover, the availability of these type-specific...
DE102008029356A1 A method for purifying nucleic acids, in particular of fixed tissue  
The invention relates to a method for purification of nucleic acids, a kit for performing the inventive method, as well as a novel use of magnetic particles for purifying a biological sample. The...
DE69930310T3 KIT AND METHOD FOR NUCLEIC SEQUENCING OF SINGLE MOLECULES BY POLYMERASE SYNTHESIS  
This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi...
DE102008025328A1 Detecting HIV in a blood sample comprises providing and optionally concentrating the sample, extracting viral nucleic acids, adding the extract to PCR master mix and performing amplification and detecting the amplified viral nucleic acids  
Method (A) for detecting HIV in a sample derived from blood comprises: (a) providing the sample derived from blood; (b) optionally concentrating the sample derived from blood; (c) extracting viral...
DE102008024309A1 New tetrahydro-pyran compounds useful to prepare 2-desoxy-2-(F-18)fluoroglucosyl-1-azide, which is useful for F-18-glycosylation of bioactive alkynyl or ethinyl derivatized molecule to form conjugated tetrahydro-pyran biomolecule  
Tetrahydro-pyran compounds (I) are new. Tetrahydro-pyran compounds of formula (I) are new. 3 of R 1-R 4= a leaving group comprising OAc and the other is OSO 2R', and R'= methyl, trifluoromethyl or...
DE19831609B4 A process for producing amino acids of the aspartate and / or glutamate family and used in the process means  
Microbial production of amino acids (A) of the asparate and/or glutamate families comprises increasing pyruvate carboxylase (PC) activity by genetic alteration of the enzyme and/or increasing...
DE102008023301A1 New nucleophilic cytosine derivatives and their applications  
The invention relates to the novel and not previously used in the synthesis of cytidines silylated cytosine analogs 4c and 4d as well as their use for reactions with 3,5-protected sugars of...
DE102008022017A1 Preparing 1,4-benzothiepin-1,1-dioxide derivative, comprises e.g. reacting mercaptomethyl-hexanol compound with difluorobenzoyl-azinic acid compound and converting into e.g. benzo(b)thiepin-4-ol compound followed by isolating and purifying  
Preparation of 1,4-benzothiepin-1,1-dioxide derivative (I), comprises e.g. reacting (S)-2-ethyl-2-mercaptomethyl-hexan-1-ol (V) with [3-(2,5-difluorobenzoyl)phenyl]azinic acid (VIII), followed by...
DE19937019B4 A method for producing 4-aryl-2-butanols from Taxus wallichiana  
The present invention provides a process for the production of two molecules of 4-aryl-2 butanols having the general formula 1 given below:Wherein R=H or glucose from the leaves of Taxus...
DE10154290B4 A method for detecting periodontal disease and caries-associated bacteria  
The invention relates to the diagnosis of microorganisms, especially the detection of microorganisms which are associated with the disease known as parodontitis or tooth decay. The information...
DE69434520T3 BIOTINYLATION PROTEINS  
Biotinylation peptides can be fused to other peptides or proteins of interest using recombinant DNA techniques to provide efficient methods for biotinylating the resulting fusion proteins in vivo...
DE102008017590A1 Glucopyranosidderivate  
New compounds of formula I whereinX has the meaning given in claim 1, useful as antidiabetic agents.
DE102005031755B4 Salmonella spp. binding peptides, nucleic acids encoding the Verwenduen and methods and kits for enrichment, immobilization and detection of Salmonella spp.  
Salmonella spp. binding peptide selected from the sequences SEQ ID NO. 1 to NO. 3, SEQ ID NO. 5 to NO. 8, SEQ ID NO. 10, SEQ ID NO. 12, SEQ ID NO. 14 to NO. 16, SEQ ID NO. 18, SEQ ID NO. 20 to NO....
DE60110094T2 DEVICE AND METHOD FOR AUTOMATED SYNTHESIS OF oligosaccharides  
One aspect of the present invention relates to an apparatus for the efficient synthesis of oligosaccharides on a solid support, e.g., formed by subunit addition to terminal subunits immobilized on...
DE69529276T2 TARGETED GENE THERAPY  
Nucleic acid constructs comprising at least one gene encoding a species having activity against disease, such as a pro-drug activation system, operatively linked to a hypoxically inducible...
DE102008012295A1 Mixture for the production of rapidly disintegrating tablets  
Isomalt-containing mixture, comprising a) 60-97 wt .-% agglomerated isomalt, b) 1-25 wt .-% cross-linked polyvinylpyrrolidone, c) 0.1-15 wt .-% lubricant, d) 1-15 wt. -% water-insoluble,...
DE102008012015A1 Improved isomalt-containing compressed formulations and methods for their preparation  
The present invention relates to improved isomalt-containing compacts and methods for their preparation.
DE602005005449T2 ADJUVANT COMPOSITIONS  
An adjuvant composition comprises a Th1-activating alkaloid, optionally further comprising an auxiliary adjuvant selected from a type 2 adjuvant (e.g. alum and/or MF59), a type 1 adjuvant and/or a...
DE102008010693A1 New matrix materials, to processes for their preparation and their use in methods for isolating biomolecules  
The present invention berifft functionalized matrix materials or matrices which have the structures of the general formula I Processes for their preparation and their use for purification and...
DE102008010584A1 Detecting anaerobic microorganisms capable of degrading aromatic compounds comprises using nucleotide sequences coding for a conserved amino acid sequence of 6-oxocyclohexene-1-carbonyl coenzyme A hydrolase  
Detecting anaerobic microorganisms that are capable of degrading aromatic compounds comprises contacting an environmental sample with nucleotide sequences coding for a conserved amino acid...
DE10084502B4 A method for purification of nucleic acid with silicon carbide  
The invention disclosed is particularly directed to a process for the purification of DNA, and is especially useful for the isolation of biologically active plasmid DNA. The process is initiated...
DE102008008270A1 Novel cyclic oxo-silanes based on sugar derivatives and process for their preparation  
Are given for the preparation thereof novel cyclic oxo-silanes based on sugar derivatives and methods. As part of the invention is, inter alia, succeeded in introducing silicon atoms at the...
DE102008008193A1 Roller- or plain bearing forgery-proof marking of a valuable document, comprises a bearing body with a surface, and a marking that enables a clear identification of the bearing body and comprises a synthetic nucleic acid  
The roller- or plain bearing (6) comprises a bearing body with a surface (1), and a marking that enables a clear identification of the bearing body and comprises a synthetic nucleic acid (4)...
DE102008006416A1 Clindamycin or its salt, or a clindamycin-containing composition useful for the intracervical or endocervical treatment or prevention of bacterial vaginosis caused by anaerobic and gram positive aerobic germs  
Clindamycin or its salt, or a clindamycin-containing composition useful for the intracervical or endocervical treatment or prevention of bacterial vaginosis caused by anaerobic and gram positive...
DE69433518T4 NUCLEIC THAT FOR A TUMOR ABSTOSSUNGSANTIGENVORLÄUFER CODED  
The invention relates to nucleic acid molecules coding for a tumor rejection antigen precursor. Specifically, the tumor rejection antigen precursor, or "TRAP", is processed into at least one tumor...
DE102008000101A1 A process for obtaining D-galactose from vegetable raw material by acid hydrolysis  
Disclosed is a method for the recovery of D-galactose, comprising the steps of:- Providing an aqueous solution or suspension of Galactoarabinan, wherein the aqueous solution or phase has a pH of...
DE69331832T3 DIAGNOSTIC METHOD AND PHARMACEUTICAL COMPOSITIONS BASED ON NOTCH proteins and nucleic acids  
The present invention relates to pharmaceutical compositions comprising a fragment of Serrate protein or a derivative or analog of said fragment, or comprising a derivative or analog of a Serrate...
DE102008054480A1 Direct sequencing by ATP release  
There is provided a method for sequencing a nucleic acid. In certain embodiments, the method comprises contacting a nucleic acid duplex comprising a template and a nucleic acid annealed to the...
DE69612772T3 Printing libraries of molecular chains  
A method and apparatus for selectively applying a print material onto a substrate for the synthesis of an array of oligonucleotides at selected regions of a substrate. The print material includes...
DE69133329T3 Selected oligonucleotides  
A process for discriminating sequence variants of a target nucleic acid is described. In this process variant specific cleavage products of a labeled oligonucleotide probe are produced by the...
DE68929299T3 Multiple genomic DNA amplification for the detection of a deletion  
The present invention relates to a method for detecting multiple DNA sequences simultaneously. The method involves amplification of multiple sequences simultaneously by annealing a plurality of...
DE60319146T2 COMPOSITIONS AND METHODS FOR DETECTION polynucleotides  
The present invention relates to compositions comprising probes for the detection of a target polynucleotide, and methods for detecting the amount of a target polynucleotide using the subject...
DE69435096T2 COMPOSITION FOR IN VIVO PRODUCTION OF THERAPEUTIC PRODUCTS  
The present invention provides cell compositions for in vivo implantation, and designed for the sustained and controlled delivery of therapeutic substances.
DE602004013372T2 IL-7 FUSION PROTEIN WITH ANTIBODY PORTIONS, THE PRODUCTION AND USE THEREOF  
The invention is directed to a fusion protein which includes a first portion including an immunoglobulin (Ig) chain and a second portion including interleukin-7 (IL-7).