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DE60214725T2 METHOD FOR DETERMINING THE EXPRESSION OF DIHYDROPYRIMIDINDEHYDROGENASEGENS  
The present invention relates to prognostic methods which are useful in medicine, particularly cancer chemotherapy. The object of the invention to provide a method for assessing Dihydropyrimidine...
DE602004002692T2 Process for the preparation of Topiramate  
The present invention relates to a process for the preparation of topiramate, intermediates in this process and a process for the preparation of these intermediates.
DE602004002366T2 Lipid A and lipid A containing topical, particularly cosmetic, composition  
Lipid A compounds (I) are new. Lipid A compounds of formula (I) are new: [Image] AG 13-hydroxydecanoyl; AG 23-dodecanoyloxydecanoyl; R : H or PO(OR') 2; R' : H, M, 1-6C (un)saturated alkyl, phenyl...
DE60128296T2 Saccharide-alkyleneoxy and ink  
A saccharide-alkyleneoxy derivative comprising a compound represented by the following formula (1): A-(EP)n-OH wherein A represents a skeleton of a saccharide selected from the group consisting of...
DE10262018B4 Compositions, foodstuffs, foods, and beverages, confectionery, pet food, dietary special diet, child nutrition, sweeteners and pharmaceutical compositions containing condensed Palatinose  
The Invention relates to compositions, food, food and beverages, Confectionery, Animal feed, dietary Special diet, Child nutrition, sweeteners and to pharmaceutical compositions containing a new...
DE69233331T3 Combinatorial Strategies for Polymer Synthesis  
A method of forming an array of polymers on a solid support, comprising:(a) moving a dispenser containing a solution of a polymer toward a surface of a solid support until a tip of the dispenser...
DE60124170T2 Use of ascorbic acid derivatives to improve the synthesis of the epidermal ceramides  
Use of ascorbic acid derivative of formula (I) as stimulant of epidermic lipogenesis. Use of at least one ascorbic acid derivative of formula (I) for improving synthesis of epidermic ceramides. R1...
DE60122777T2 RECOVERING xylose  
The invention relates to a process of producing a xylose solution from a biomass hydrolysate by subjecting the biomass hydrolysate to nanofiltration and recovering as the nanofiltration permeate a...
DE60122345T2 PKSs WITH MODIFIED SPECIFICITY, THEIR PRODUCTION AND USE  
Biosyntheses of compounds whereof at least portions are polyketides produced by means of polyketide synthase (PKS) enzyme complexes are carried out after specific alterations have been made within...
DE60031320T2 A method for detecting antisense oligonucleotides and peptide nucleic acids  
Antisense oligonucleotide sequences which enable the measurement of the distribution and structure of antisense oligonucleotide drugs in the body, with lapse of time, and a method of detecting...
DE60030286T2 CONTROL OF GENE EXPRESSION IN CELLS EUCARYOTIC  
DNA constructs and other compositions and methods for controlling gene expression in eukaryotic cells and organisms are derived from bacterial quorum sensing systems. One or more cis elements from...
DE4411176B4 Developer for PS plates and supplemental fluids for developer  
developer for presensitized photosensitive plates for making lithographic printing plates, containing an alkali metal silicate having a molar ratio SiO2/ M2O (wherein M represents an alkali metal...
DE102006008701A1 Procedure for transferring biomolecules into a cell, comprises preparing a complex from biomolecule and polymer, and transferring the biomolecule into a cell by contacting the cell with the complex  
Procedure for transferring biomolecule into a cell, comprises preparing a complex from the biomolecule, preferably nucleic acid, and a polymer, which is obtained through reacting an amine-monomer...
DE69133552T2 Non-A, non-B hepatitis virus antigen, and diagnostic procedures.  
Sequence (I) comprises (a) the Hutch c59 DNA sequence shown in SEQ ID NO:46 of the spec; (b) degenerate sequences of the sequence of (a); (c) a mutant variant of the NANBV Hutch c59 strain with...
DE60215157T2 USES OF ANTIVIRAL NUCLEOSIDE DERIVATIVES FOR THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF HEPATITIS C INFECTION  
The present invention comprises nucleoside derivatives for use in the treatment or prophylaxis of hepatitis C virus infections. In particular, the present invention discloses the novel use of...
DE60213407T2 COMPOSITIONS FOR INHIBITING ANGIOGENESIS  
Methods for inhibiting angiogenisis are disclosed the comprise administering oleouropein and/or the products of its hydrolysis in therapeutically effective amounts. The methods and compositions of...
DE60122156T2 NEW disaccharides ANTI-arthritic EFFECT  
This invention refers to new disaccharides of formula (I), where R<1> is selected from the group consisting of hydrogen, linear or branched (C1-C4)-alkyl, phenylalkyl of less than ten carbon atoms...
DE60031793T2 Doxorubicin and daunorubicin-CONTAINING AGENTS AND THEIR THERAPEUTIC APPLICATIONS cytotoxic  
A cytotoxic agent comprising one or more modified doxorubicins/daunorubicin linked to a cell binding agent. A therapeutic composition for killing selected cell populations comprising: (A) a...
DE69935782T2 BREAST CANCER RESISTANCE PROTEIN (BCRP) AND FOR THIS CODING DNA  
The Breast Cancer Resistance Protein is described, as well as the cDNA encoding said protein. This protein has been found to confer resistance to cancer chemotherapeutic drugs.
DE69133556T2 Methods and compositions for the synthesis of BCH-189 and related compounds  
The present invention relates to a method of preparing BCH-189 and various analogues of BCH-189 from inexpensive precursors with the option of introducing functionality as needed. This synthetic...
DE60307749T2 Use of flavonoid derivatives for the treatment of atopic eczema  
The invention relates to the use of certain flavonoid derivatives for the preparation of formulations which are suitable for the prophylaxis and/or therapy of eczema. The formulations are...
DE60307503T2 Antiviral nucleoside  
The present invention relates to nucleoside derivatives for the treatment of Hepatitis C viral infections including compounds of formula I, pharmaceutical compositions comprising these compounds...
DE602004002696T2 NEW 14- AND 15-PRONGED RING COMPOUNDS  
The present invention relates to 14- or 15-membered macrolides substituted at the 4'' position of formula (I) and pharmaceutically acceptable derivatives thereof, to processes for their...
DE19720839B4 Modular technology for the production of long, exact DNA constructs in vitro, in particular for the preparation of constructs for the production of artificial chromosomes (MAC, mammalian artificial chromosome) of two stable cloned DNA components and the prototype vector ditelomerische PTAT  
The invention relates to a method for producing a DNA construct, whereby two or several DNAs are recombined in melted agarose. The invention also relates to vectors which can be used therefor, in...
DE69835308T2 Prodrugs and conjugates of Selenoenthaltenden compounds and their use  
Disclosed are prodrugs as follows:(I) a prodrug of the formulawhere A is a sulfur or a selenium, and R is a mono- di- or oligo-saccharide;(II) a prodrug of the formulawhere A is sulfur or...
DE69736840T2 Synthesis of nucleosides and polynucleotides  
Novel nucleosides, process for chemical synthesis of nucleosides and incorporation of the nucleosides into polynucleotides are disclosed. Also described are polynucleotides, such as antisense, TFO...
DE69736331T2 IMMUNE STIMULATING NUKLEINSAEUREMOLEKUELE  
An isolated immunostimulatory oligonucleotide comprising two or more unmethylated CpG dinucleotides, and having a sequence including the following formula: €ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ5'N 1 X 1 X 2 CGTTN 2 3'...
DE69535260T2 Using a non-neutralizing antibody specific for the beta-subunit of luteinizing hormone for enhancing fertility  
The present invention relates to methods for enhancing fertility by reducing the activities and/or levels of circulating glycoprotein hormones having lutropin (LH) activity. The molecules of the...
DE60121615T2 PROCESS FOR PRODUCING OPTICALLY ACTIVE anthracyclines  
It is described a process for the synthesis of optically active anthracyclines by the fact that the key intermediate (R)2-acetyl-2-hydroxy-1,2,3,4-tetrahydronaphtalene...
DE20122767U1 Massive parallel method for decoding DNA and RNA  
This invention provides methods for attaching a nucleic acid to a solid surface and for sequencing nucleic acid by detecting the identity of each nucleotide analogue after the nucleotide analogue...
DE102005033903B4 Perfluoroalkyl-containing complexes, processes for their preparation, and their use and pharmaceutical compositions containing them  
Perfluoroalkyl-containing metal complexes (I) are new. Perfluoroalkyl-containing metal complexes of formula K1>-L(Q-R)-N(A)-X-Rf (I), are new. R : mono- or oligosaccharide bound with one hydroxy...
DE69736420T2 Esterase gene and its use  
A gene is described coding for an esterase capable of causing asymmetric hydrolysis of an organic carboxylic acid ester of a cyclopentenolone of formula I: wherein R1 is C1-C10 alkyl, C2-C10...
DE10138935B4 Synthetic compounds from non-mucin or its conjugated with a carrier compounds, monoclonal antibodies produced using them, this comprehensive anti-tumor agent and immune stimulants means to human immunodeficiency virus  
The purposes of this invention are preparation of the non-mucin type synthetic compounds-carrier conjugated compounds which are stable against enzymes, and which have the ability of specific...
DE69932362T2 Desulfurization AND METHOD FOR DESULFURIZATION OF HYDROCARBONS  
The present invention provides a desulfurizing agent manufacturing method which is characterized in that a mixed aqueous solution containing a copper compound and a zinc compound and an aqueous...
DE69636339T2 GROWTH INHIBITORS AGAINST leukemic CELLS OF ANTISENSE oligonucleotide derivatives AGAINST Wilms' tumor gene CONTAINS  
A leukemic cell growth inhibitor containing antisense oligonucleotide derivatives against Wilms' tumor gene (WT1).
DE69334100T2 ELK LIGAND, ON CYTOKINE  
Antibodies to elk ligand (elk-L) polypeptides as well as DNA sequences, vectors and transformed host cells useful in providing elk-L polypeptides. The elk-L polypeptide binds to a cell surface...
DE60214134T2 MODIFIED PSMA LIGANDS AND THEIR USE  
The instant invention provides reagents and methods for diagnosis, detection and treatment of cancers (for example, prostate cancers). In particular, the invention provides methods to generate...
DE60029589T2 METHOD FOR PRODUCING AZITHROMYCIN  
Azithromycin in the form of a stable monohydrate and processes for the preparation of azithromycin in the form of an, e.g. stable, monohydrate.
DE202007003503U1 Galatenoside and their use as antidepressants  
Polygalatenosid the following structure: comprising racemic mixtures of optically active compounds or optically pure R and S stereoisomers, in which R, R 'and R' 'independently H or R1 constitute,...
DE19903056B4 HPV Assay  
process to amplify existing in biological samples HPV DNA, characterized in that a) a sample optionally subjecting a protease digestion, b) the nucleic acids separating of protease and other...
DE102006001759A1 Synthesis of metal nanoparticles and nanocrystals, useful particularly for silver disinfection of e.g. medical instruments, uses a silicatein protein, also new silicateins and nucleic acid encoding them  
Method for synthesizing nanoparticles and nanocrystals (X) from gold, silver and other transition metals that uses a protein (I), or its metal complex, where (I) comprises an animal, bacterial,...
DE69636997T2 HEALING AND PREVENTING BY NF-kappaB CAUSED DISEASES  
Administration of a decoy, i.e. a compound which specifically antagonizes the nucleic acid domain to which NF- kappa B is bound, is effective in the treatment and prevention of diseases caused by...
DE60121557T2 METABOLITES OF ESTROGEN agonists / antagonists  
This invention relates to compounds that are mammalian metabolites of (-)-cis-6-phenyl-5-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-5,6 ,7,8-tetrahydro-naphthalene-2-ol. The compounds of the invention...
DE60029314T2 Improved Synthesis of -2.2.1. I bicyclo nucleosides  
A synthesis of [2.2.1]bicyclo nucleosides which is shorter and provides higher overall yields proceeds via the key intermediate of the general formula III, wherein R4 and R5 are, for instance,...
DE19981703B4 A process for increasing the purity of the racemic form of metallocene  
Disclosed is a process for the preparation of metallocone complexes wherein stereoisomers of metallocene complexes formed at the time of synthesis can easily be separated. The gist of the present...
DE69933539T2 PHARMACEUTICAL COMPOSITION CONTAINING baicalin, chlorogenic acid and forsythiaside IN isolated and purified form AND METHOD FOR PRODUCING  
The present invention provides a pharmaceutical composition comprising an extract or combination of extracts having an antiviral, antibacterial, or immunomodulating property, wherein the extract...
DE69932346T2 based on morpholine p53 antisense oligonucleotide and its uses  
Antisense oligonucleotides useful for treating a disease state characterized by p53 induction, such as proliferative cell disorders, e.g. cancer, or a hypoxic state induced by an ischemic attack,...
DE69636147T2 METHOD FOR PRODUCING phosphorothioate OLIGOMERIC  
Methods and intermediates for the preparation of oligomers containing diastereomerically enriched phosphorothioate linkages are disclosed.
DE69334092T2 Detection of Mycobacterium tuberculosis by amplification of nucleic acid sequences  
The invention relates to kits, oligonucleotides and method for amplifying M. tuberculosis rRNA.
DE69132521T3 HOMOGENEOUS TEST SYSTEM  
A process for discriminating sequence variants of a target nucleic acid is described. In this process variant specific cleavage products of a labeled oligonucleotide probe are produced by the...