Match Document Document Title
DE69932346T2 based on morpholine p53 antisense oligonucleotide and its uses  
Antisense oligonucleotides useful for treating a disease state characterized by p53 induction, such as proliferative cell disorders, e.g. cancer, or a hypoxic state induced by an ischemic attack,...
DE69636147T2 METHOD FOR PRODUCING phosphorothioate OLIGOMERIC  
Methods and intermediates for the preparation of oligomers containing diastereomerically enriched phosphorothioate linkages are disclosed.
DE69334092T2 Detection of Mycobacterium tuberculosis by amplification of nucleic acid sequences  
The invention relates to kits, oligonucleotides and method for amplifying M. tuberculosis rRNA.
DE60310923T2 PRODUCTION OF CRYSTAL MATERIALS BY HIGH PERFORMANCE ULTRASOUND  
A crystalline material sufficiently pure for use in pharmaceuticals may be made by forming a saturated solution of the material, changing the temperature of the solution so it becomes...
DE60122193T2 Glucopyranosyloxybenzylbenzene DERIVATIVES AND MEDICAL COMPOSITIONS CONTAINING THESE COMPOUNDS  
The present invention relates to glucopyranosyloxybenzylbenzene derivatives represented by the general formula: wherein P represents a group forming a prodrug; and R represents a lower alkyl...
DE10241208B4 Presbyopiekorrigierende contact lens and methods of manufacture for such a contact lens  
Presbyopiekorrigierende Contact lens (1, 20, 30, 60) with at least one near-vision zone (8, 21, 32, 66) with high refractive power and at least one far vision zone (9, 22, 33, 65) with a lower...
DE69836321T2 Plant extracts having appetite suppressant activity  
A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for...
DE69535155T2 FOR GDNF ENCODING RECOMBINANT ADENOVIRUSES  
Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic growth factor (GDNF) are provided. The recombinant adenoviruses are useful in a method of...
DE69535074T2 PEPTIDE FRAGMENT OF G-PROTEIN OF respiratory syncytial virus, IMMUNOGENIC CONNECTION AND PHARMACEUTICAL COMPOSITION, WHICH CONTAIN, AND MANUFACTURING METHOD  
New polypeptides (I) useful as immunogenic elements comprise a peptide sequence between amino acids 130 and 230 of the protein G sequence of respiratory syncytial virus (RSV) subgroup A or B, or a...
DE60121545T2 VIRUS porcine reproductive and respiratory SYNDROME AND USE THEREOF  
The present invention provides isolated European-like porcine reproductive and respiratory syndrome viruses, polynucleotides, and polypeptides. The present invention also provides methods for...
DE102005063244A1 New 2-nitroimidazole derivatives, useful for detecting hypoxic tissue especially associated with tumors, diabetes, stroke and/or circulatory diseases, have substituent that mediates transport into biological cells  
New 2-nitroimidazole derivatives (I) have a substituent (or vehicle) that mediates transport into biological cells via cellular transport systems. Independent claims are also included for the...
DE69934088T2 METHOD FOR IN VITRO AMPLIFICATION CIRCULAR DNA  
A method for generating and amplifying closed circular DNA having a specific sequence in vitro in a cell-free system is disclosed. Prior to the invention of this method, closed circular DNA could...
DE69933578T2 PRODUCING HIGHLY PURE L-ribose OFF L-ARABINOSE  
A process of preparing a L-ribose fraction having greater than 97% purity starting from an aqueous solution of L-arabinose is provided by utilizing an epimerization reaction conducted in the...
DE69736197T2 Anticoagulant humanised antibodies against factor IX, for use in the treatment of thrombosis  
Monoclonal antibodies directed against coagulation factors and their use in inhibiting thrombosis is disclosed.
DE69535326T2 TRANSFORMED LINE OF YEAST CANDIDA UTILIS AND THUS BE AN EXPRESSION HETEROGENS  
A GAP-gene promoter sequence, a GAP gene terminator sequence and a gene expression unit comprising same.
DE60215866T2 DRUG CONTAINING cyanidin 3-glycoside AS ACTIVE AGAINST OBESITY AND DIABETES  
The invention provides an antiobestic and/or antidiabetic agent containing cyanidin 3-glucoside as an active ingredient. Thereby the increase of adipose cells can be suppressed and the blood...
DE60123481T2 METHOD FOR CARRYING subtractive hybridization  
The subject invention relates to improvements in nucleic acid isolation, and more particularly, relates to modifications to the subtractive hybridization method and to reagents such as...
DE69934892T2 Water-AZALIDLĂ–SUNG  
Water miscible pharmaceutical compositions containing up about 40% of a marcrolide such as an azalide antibiotic are prepared by reaction of the macrolide with acid in a non-aqueous water miscible...
DE69836326T2 A method for cellular communication, cell, communication system and corresponding network terminal  
The header size reduction system has a complete header (22) associated with a stream of digital information (23). The header provides virtual path routing (VPI) and other synchronizing information...
DE69835201T2 neoglycoproteins  
Polyamide conjugates comprising either (a) a xenoantigenic group; or (b) a biologically active group and a macromolecular, macro- or microscopic entity; bound to a polyamide backbone, processes...
DE69434782T2 METHOD FOR PRODUCING RECOMBINANT, BIOLOGICALLY ACTIVE POLYPEPTIDES  
Polypeptides, polynucleotides, fragments thereof, and monoclonal antibodies thereto are provided for antigen-specific and antigen-non-specific glycosylation inhibiting factor and a method for...
DE60305741T2 NEW SEMI SYNTHETIC macrolide THE AZALIDREIHE  
The invention relates to N''-substituted 9a-N-(N'-carbamoyl-gamma-aminopropyl), 9a-N-(N'-thiocarbamoyl-gamma-aminopropyl), 9a-N-[N'-beta-cyanoethyl)-N'-carbamoyl-gamma-aminopropyl] and...
DE3650788T2 Production of pluripotent granulocyte colony stimulating factor  
Disclosed are novel polypeptides possessing part or all of the primary structural conformation and one or more of the biological properties of a mammalian (e.g., human) pluripotent granulocyte...
DE102005059242A1 Molecular markers for tumor diagnosis and therapy  
The This invention relates to the diagnosis, prognosis, monitoring and therapy of neoplastic diseases such as tumor diseases, in particular Cancers of the endometrium and their metastases.
DE102005058542A1 Erythruloseester as UV filters  
The Invention relates to compounds according to formula I, wherein X, Y and Z are O, NH or N-alkyl, Sp, Sp ', Sp' 'can be identical or different and are -H, - (CH2)n-, - (CH2)n-C (= O) - (CH2)O-...
DE102005058431A1 Nucleic acid useful as a target for detecting species of yeasts and/or filamentous fungi comprises an elongation factor 3 gene or a fragment thereof  
Nucleic acid (I) comprising the elongation factor 3 gene of yeasts and filamentous fungi or a fragment thereof is new. New nucleic acid (I) comprises a nucleic acid (Ia) with a sequence selected...
DE69932173T2 adenine  
The present invention provides compounds of formula (I):and pharmaceutically acceptable salts and solvates thereof, together with processes for the preparation of, compositions containing, uses of...
DE69636544T2 EXPRESSION OF LIPOPROTEINS  
Heterologous lipidated proteins formed recombinantly are disclosed and claimed. The expression system can be E.coli. The heterologous lipidated protein has a leader sequence which does not...
DE69535327T2 Monocytes PROTEIN RECEPTORS OF MAMMALS WITH CHEMO ATTRACTION TRIP SANTANDER EFFECT  
PCT No. PCT/US95/00476 Sec. 371 Date May 25, 1995 Sec. 102(e) Date May 25, 1995 PCT Filed Jan. 11, 1995 PCT Pub. No. WO95/19436 PCT Pub. Date Jul. 20, 1995DNAs encoding receptors for the...
DE69535240T2 Compositions and methods for the simultaneous detection and quantification of a majority of specific nucleic acid sequences  
The invention relates to methods for simultaneously or sequentially detecting multiple nucleic acid analytes in a single medium utilizing oligonucleotide hybridization probes coupled to different...
DE69031237T3 A method for purifying nucleic acids  
The invention relates to a process, a combination of means for isolating nucleic acid from a nucleic acid-containing starting material and a testkit in order to amplify the nucleic acid obtained...
DE60215310T2 METHOD FOR DEHDRATISIEREN OF WATER CONTAINING MATERIAL WITH A cyclotetrasaccharide  
The present invention has the object to dehydrate hydrous matters without denaturing or deteriorating them by using a dehydrating agent comprising an anhydrous cyclotetrasaccharide, and provides a...
DE602004003054T2 NEW 3-decladinosyl-9A-N-carbamoyl and 9A-N-THIOCARBAMOYLDERIVATE OF 9-deoxo-9-dihydro-9A-AZA-9A-homoerythromycin A  
The present invention relates to the new 3-decladinosyl derivatives of 9a-N-carbamoyl- and 9a-N-thiocarbamoyl-9-deoxo-9-dihydro-9a-aza-9a-homoerythromy cin A of the general formula (I), their...
DE60120486T2 A COMPLETELY CONTROLLED INTERNAL amplification enabling COMPOSITIONS AND METHODS  
The present invention provides compositions and methods for performing an amplification reaction of nucleic acids with internal controls that test the integrity of all aspects of the amplification...
DE60028544T2 PROSTATE SPECIFIC GENE FOR THE DIAGNOSIS, PROGNOSIS AND TREATMENT OF PROSTATE CANCER  
Disclosed are nucleic acid and amino acid sequences encoded by a novel, prostate specific gene (UC41) and diagnostic techniques for the detection of human prostate cancer utilizing such nucleic...
DE102005057334A1 A method for isolating nucleic acids from any starting materials  
object the invention is a universal and highly simplified procedure for isolating nucleic acids of nucleic acids containing diverse feedstocks using a combination from buffers with chaotropic...
DE10051628B4 Single stranded oligonucleotide and its use  
Single stranded oligonucleotide with a Konjungat, wherein the oligonucleotide four specific nucleotides includes, characterized in that the four specific nucleotides only the carry base cytosine...
DE69933875T2 PROTEIN DELIVERY SYSTEM, THE HUMAN PAPILLOMAVIRUS SIMILAR PARTICLE used.  
Human Papillomavirus virus like particles (VLPs) have been constructed so that they contain a modified L2 protein. The L2 protein has been minimized and is fused to a second protein or peptide....
DE69933860T2 2'-FLUORONUKLEOSIDE  
2'-Fluoronucleoside compounds are disclosed which are useful in the treatment of hepatitis B infection, hepatitis C infection, HIV and abnormal cellular proliferation, including tumors and cancer....
DE69932154T2 USE OF N-SUBSTITUIRTEN-1,5-dideoxy-1,5-imino-D-GLUCITOLEN FOR THE TREATMENT OF HEPATITIS INFECTIONS  
Provided are methods and compositions for treating hepatitis virus infections in mammals, especially humans. The methods comprise (1) administering N-substituted-1,5-dideoxy-1,5-imino-D-glucitol...
DE69535316T2 ALS LERK6 designated CYTOKINE  
The invention is directed to LERK-6 as a purified and isolated protein, the DNA encoding the LERK-6, host cells transfected with cDNAs encoding LERK-6.
DE69233630T2 Rates of HIV probes for use in sandwich Hydridisierungsassays in solution phase  
Novel DNA probe sequences for detection of HIV in a sample in a solution phase sandwich hybridization assay are described. Amplified nucleic acid hybridization assays using the probes are exemplified.
DE60309345T2 INOSITOLDERIVATISIERTE PHOSPHOLIPIDS  
The present invention relates to a phospholipid derivative having a substituted or unsubstituted polyhydroxylated aliphatic carbocycle attached to the sn-1 or sn-2 position of the glycerol...
DE60215530T2 NEW glycolipid, AND REMEDIES FOR AUTOIMMUNE THIS IS AS ACTIVE INGREDIENT  
Glycolipid compounds (I) are new. Glycolipid compounds of formula (I) are new. [Image] R 1aldopyranose residue; R 2H or OH; R 3CH 2, CH(OH)CH 2 or CH=CH; R 4H or CH 3; x : 0-35; y+z : 0-3....
DE60124245T2 Uridine AS ANTIBIOTICS  
All possible isomeric forms of a compound of the formulawhere the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts useful as antibiotics.
DE69932926T2 GEN CODING FOR Labyrinthin, A CANCER MARKER  
A cDNA molecule that encodes a protein designated Labyrinthin (Lab) isolated and its nucleotide sequence is determined. The protein, or peptides derived from the protein, are markers useful to...
DE69932187T2 LINKS FOR CANCER THERAPY  
It is shown that the potency of anti-cancer drugs, here exemplified by doxorubicin, can be increased by the use of polyunsaturated fatty acid amides and in particular specific combinations of such...
DE69133545T2 A process for the preparation of specific binding pair members,  
A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are...
DE60215315T2 USE OF FUSION PROTEINS WHOSE N-terminal part FROM A hirudin EXISTS FOR PRODUCING PROTEIN BY SECRETION BY YEASTS RECOMBINANT  
Nucleic acid sequence including: Px-Sx-Bn-(ZR)-Hir(AsmR)-protein(Y)-T. Px is a promoter sequence. Sx is a nucleic acid encoding a signal sequence or leader sequence. Bn is 1-15 codons, when n is...
DE60030965T2 CONJUGATES CONTAINING FISSILE TIE ONE ON THE APPLICATION in a liposome  
A compound comprised of a hydrophilic polymer covalently yet reversibly linked to a amine-containing ligand through a dithiobenzyl linkage is described.