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DE102006032569A1 Silylating poly-, oligo-, disaccharides derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent  
Silylating poly-, oligo-, disaccharides or their derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent. An...
DE69935927T2 PLASMID STABILIZATION SYSTEM FOR THE ADMINISTRATION OF ANTIGENES  
The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid...
DE69133552C5 Deoxyribonucleic acid sequence encoding non-A, non-B hepatitis virus - obtd. Hutch C59 subgroup encoding polypeptide(s), useful as vaccines, and immuno reactive ABS for diagnosis of virus  
Sequence (I) comprises (a) the Hutch c59 DNA sequence shown in SEQ ID NO:46 of the spec; (b) degenerate sequences of the sequence of (a); (c) a mutant variant of the NANBV Hutch c59 strain with...
DE602004005826T2 METHODS FOR CLEANING OF STABLE RADIOIODIUM CONJUGATES  
The present invention is directed toward a method for preparing and purifying a conjugate of a radioiodinated aminopolycarboxylate-appended peptide and a targeting agent. The method involves (A)...
DE602004005752T2 NEW DERIVATIVES OF MORPHINE-6-glucuronide, THESE DERIVATIVES pharmaceutical compositions containing, MANUFACTURING AND METHODS OF USE THEREOF  
Morphine-6-glucuronide derivatives (I) and their salts are new. Morphine-6-glucuronide derivatives of formula (I) and their salts are new; [Image] R 1>1-10C linear or branched alkyl, optionally...
DE60128070T2 VACCINE SPECIFICALLY AGAINST KIDNEY TUMORS, directed against the antigen G-250 RENAL TUMOR  
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers expressing a G250 antigenic marker....
DE60032388T2 CRYSTALLINE MIXTURES OF TEILMETHYLETHERN OF BETA-cyclodextrin and RELATED LINKS  
Certain mixtures of cyclodextrin derivatives, which were synthesized in mildly basic conditions, can be separated into mixtures that crystallize easily and mixtures of similar composition, which...
DE19528029B4 Magnetic polymer particles based on polyvinyl alcohol, process for their preparation and use  
Spherically shaped polyvinyl alcohol (PVAL) polymer particles are prepared encapsulating a magnetic colloid that provides the particles with magnetic properties for use in binding biomolecules....
DE10109466B4 Method and means for modification of human angiogenesis  
process to induce angiogenic processes in tissues of a mammalian organism, comprising the steps of: - Preparation of a ternary complex by complexing a nucleic acid molecule as a functional...
DE69737633T2 TO fibroblast growth factor HOMOLOGOUS FACTORS (FHFS) AND METHOD OF ADMINISTRATION  
The invention provides fibroblast growth factor homologous factor (FHF) polypeptides and nucleic acid molecules that encode them. Also included in the invention are diagnostic and therapeutic...
DE69535501T2 IDENTIFICATION, CLEANING AND USES OF LECZYMEN AND KARBOHYDRATLIGANDEN  
The present invention provides a substantially purified carbohydrate ligand that specifically binds to a leczyme. The invention also provides methods to identify a carbohydrate ligand that...
DE69535476T2 Substituted 1,3-oxathiolanes with antviralen properties  
This invention relates to single enantiomers of novel cis-substituted 1,3-oxathiolanes, of formula (I) wherein R1 is hydrogen, and R2 is cytosine or 5-fluorocytosine, and pharmaceutically...
DE69133568T2 Bacteriophage particles which present dAbs  
A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are...
DE60219653T2 PHARMACEUTICAL COMPOSITION WITH CHITO-OLIGOMERS  
Compositions are provided comprising chito-oligomers obtainable from chitin, comprising oligomers of N-acetyl glucosamine (NAG) and glucosamine, wherein at least 50% of the oligomers have a chain...
DE60128002T2 RECEPTOR NUCLEIC AND RECEPTOR POLYPEPTIDES  
Disclosed are nucleic acids encoding BAFF-R polypeptides, as well as antibodies to BAFF-R polypeptides and pharmaceutical compositions including same. Methods of treating tumorigenic and...
DE3890998B4 Neutrophilenaktivierungsfaktor, process for its preparation and pharmaceutical composition containing it  
Neutrophil-activating factor (NAF) is claimed. More specifically it has the qiven complete amino acid sequence. Also claimed is DNA having the nucleotide sequence indicated and equivalents...
DE69935828T2 Alkaline ceramidase (EC 3.5.1.23) coding gene from Pseudomonas aeruginosa  
Ceramidase of Pseudomonas aeruginosa AN17 isolated from the skin of a patient with atopic dermatitis. Gene encoding for such a ceramidase and their variants. Probes or primer hybridizing with the...
DE69737598T2 NANOPARTICLES WITH THE FACT attached Oligonucleotides AND THEIR USES  
A method of detecting a nucleic acid having at least two portions comprises providing nanoparticles having oligonucleotides attached thereto; providing one or more types of binding...
DE69637047T2 INDEPENDENT APPARATUS FOR EXTRACTION, AMPLIFICATION AND DETECTION OF NUCLEIC  
A self-contained device is described that integrates nucleic acid extraction, specific target amplification and detection into a single device. This integration permits rapid and accurate nucleic...
DE60313290T2 PROCEDURE FOR ACCESS TO MICROBIAL DIVERSITY  
A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining a...
DE60219652T2 Chromogenic in situ hybridization METHOD, KITS AND COMPOSITIONS  
The present invention relates to chromogenic (calorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides...
DE602004006153T2 CRYSTAL CONNECTION OF 4'-demethyl-4'-PHOSPHATE-2 ', 3' '- BISPENTAFLUORPHENOXYiACETYL-4' ', 6' '- ethylidene-.beta.-D-EPIPODOiPHYLLOTOXINiGLUKOSID EITHER IN FREE FORM OR solvated with ETHANOL  
Crystalline epipodophyllotoxin 4'-demethyl-4'-phosphate 2'',3''-bis-(pentafluorophenoxyacetyl)-4'',6''-ethylidene-be ta -D-glucoside (I), as free base or hemiethanolate, is new. Crystalline...
DE60128093T2 INTERFERON-LIKE PROTEIN Zcyto21  
The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-± at the amino acid sequence level....
DE102006029306A1 Silylation of polysaccharide, especially cellulose, to give products for use in the textiles, food, building and paint industries, involves dissolving in ionic liquid and reacting with a silylating agent  
A method for the silylation of poly-, oligo- or di-saccharides or their derivatives involves dissolving these compounds in ionic liquid(s) and reacting them with a silylating agent.
DE69819150T3 IMMUNE STIMULATING OLIGONUCLEOTIDE, COMPOSITIONS THEREOF, AND METHOD FOR USE THEREOF  
The invention relates to oligonucleotides which comprise a hexameric nucleotide sequence of the formula 5'-Purine-Purine-[Y]-[Z]-Pyrimidine-Pyrimidine-3' or 5'...
DE60316189T2 P153- P156 AND ANTIGENS FOR DIAGNOSIS OF IMMUNE Ehrlichiosis in Dogs AND HUMAN AND USES THEREOF  
Sequences encoding two immunoreactive glycoproteins were cloned from Ehrlichia canis (p153 gene) and Ehrlichia chaffeensis (p156 gene). These two glycoproteins are species-specific immunoreactive...
DE60034354T2 COMPOUNDS FOR THE PROTECTION OF HYDROXYL AND ITS APPLICATION  
A hydrocarbyldithiomethyl-modified compound of the Formula: R1-O-CH2-S-S-R2 or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/or blocking...
DE102006028165A1 A process for the acylation of cellulose  
The This invention describes a method for the acylation of Poly-, oligo- or disaccharides or derivatives thereof, by this in an ionic liquid triggers and reacted with a ketene, and new acylated...
DE102004047722B4 A method for isolating and separating carbohydrates from aqueous media and use of ionic liquids for the extraction of carbohydrates  
The invention relates to a method for isolating and separating carbohydrates, especially monosaccharides, disaccharides and/or oligosaccharides, from aqueous media, which is characterized by...
DE69637018T2 METHOD FOR DIAGNOSIS OF hereditary hemochromatosis  
New genetic markers for the presence of a mutation in the common hereditary hemochromatosis (HH) gene are disclosed. The multiplicity of markers permits definition of genotypes characteristic of...
DE69535459T2 Monoclonal antibodies SPECIFIC TO VEGF RECEPTORS AND THEIR USE  
Monoclonal antibodies that specifically bind to an extracellular domain of a VEGF receptor and neutralize activation of the receptor are provided. In vitro and in vivo methods of using these...
DE60127561T2 PHAGE DEPENDENT SUPER PRODUCTION OF BIOLOGICALLY ACTIVE PROTEIN AND PEPTIDES  
This invention relates to a method for enhancing the production of biologically active proteins and peptides in bacterial cells by infecting bacterial cells of the producer strain, which contain a...
DE60127140T2 Amphotericin B CONTAINING STRUCTURED EMULSION  
Parenteral compositions of oil-coated-Amphotericin B in structured-emulsion form, having LD50 of at least 400 mg/kg in mice and process for making the same have been described. The process...
DE3752391T2 Rat protein kinase C and methods for making  
Rat protein kinase C, recombinant DNA containing DNA sequence coding for rat kinase C, a transformant transformed with a vector containing the above recombinant DNA, and the production method of...
DE19758788B4 Stereo-selective hydrogenation of sugars to sugar alcohols with good purity - in aqueous solution, at high temperature and pressure, uses catalyst mixture of Raney metal and its alloy with inert core and active shell  
Hydrogenation of 1 or more sugars to sugar alcohols in aqueous solution comprises using hydrogen (H2) at elevated temperature and pressure and a catalyst with an inert core and catalytically...
DE69934998T2 ANTISENSE MODULATION OF EXPRESSION OF ALPHA 4 INTEGRIN  
Compositions and methods are provided for modulating the expression of integrin alpha 4. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding integrin...
DE69434885T2 Allergenic proteins and peptides from dust mites and their uses  
Isolated nucleic acids encoding allergens of the species Dermatophagoides pteronyssinus and Dermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a...
DE60218891T2 SACCHARIDE-CONTAINING FUNCTIONAL ORGANOPOLYCARBOSILOXANE AND METHOD FOR PRODUCING  
A saccharide residue-functional organopolycarbosiloxane containing at least two monosaccharide or polysaccharide groups per molecule in which a specific site on the monosaccharide or...
DE60218723T2 SACCHARIDE-CONTAINING FUNCTIONAL AND METHOD FOR PRODUCING organopolysiloxanes  
A saccharide residue-functional organopolysiloxane containing at least two monosaccharide or polysaccharide groups per molecule in which a specific site on the monosaccharide or polysaccharide is...
DE60218710T2 GEN AND PROTEIN TO RELATED hepatocellular carcinoma  
The present invention provides a novel human gene ZNFN3A1 whose expression is markedly elevated in a great majority of HCCs compared to corresponding non-cancerous liver tissues. The gene encodes...
DE102006025154A1 Mutated DNA polymerase with increased reverse transcriptase activity  
The This invention relates to a DNA polymerase with increased reverse Transcriptase activity, which compared to the wild-type variant at least one mutation in their amino acid sequence comprises,...
DE102006025153A1 Mutant DNA polymerases with higher selectivity  
The This invention relates to a DNA polymerase with increased mismatch discrimination, which compared to the wild-type variant at least one mutation in their amino acid sequence comprises, as well...
DE69935599T2 MODIFIED HCV PEPTIDE VACCINES  
Provided are an isolated peptide having the amino acid sequence DLMGYIPAV (SEQ ID NO: 1), an isolated HCV core polypeptide comprising an L->A substitution at amino acid position 139, an isolated...
DE69935597T2 METHOD FOR PRODUCING SELBSTINDUZIERENDER SYNTHASE  
Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also...
DE69935513T2 ANTIBACTERIAL COMPOUNDS  
Compounds of formulae (XI), (XII), (XIV), (XV) and (XVI), as well as amide derivatives of compounds of formula (XIII), described herein, can be obtained from the cultivation products of a strain...
DE69434940T2 1,2-dioxetanes with improved chemiluminescence  
Novel 1,2-dioxetanes with improved chemiluminescent properties, such as signal intensity, S/N ratio, T½, -etc. are provided by spiroadamantyl 1,2-dioxetanes, wherein the remaining carbon atom of...
DE60312128T2 A method for immobilizing a biomolecule on a support  
Fixing a biomolecule to a synthetic or natural resin-made carrier, comprising spotting a solution of biomolecules onto the carrier and irradiation with ultra-violet rays, is new. An independent...
DE60218840T2 Not alloyed core-shell nanoparticles  
The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle...
DE602004005502T2 COMT INHIBITORS  
The present invention relates to compounds of formula I wherein R1 is as defined in the specification and to esters thereof which are hydrolyzable under physiological conditions and to the...
DE60126482T2 Single chain antibodies AGAINST P53 MUTANT  
More than 90% of mutations found in the p53 protein produce a conformational change in p53 which results in the exposure of an epitope, which is otherwise hidden in the hydrophobic core of the...