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DE10109466B4 Method and means for modification of human angiogenesis  
process to induce angiogenic processes in tissues of a mammalian organism, comprising the steps of: - Preparation of a ternary complex by complexing a nucleic acid molecule as a functional...
DE69737633T2 TO fibroblast growth factor HOMOLOGOUS FACTORS (FHFS) AND METHOD OF ADMINISTRATION  
The invention provides fibroblast growth factor homologous factor (FHF) polypeptides and nucleic acid molecules that encode them. Also included in the invention are diagnostic and therapeutic...
DE69535501T2 IDENTIFICATION, CLEANING AND USES OF LECZYMEN AND KARBOHYDRATLIGANDEN  
The present invention provides a substantially purified carbohydrate ligand that specifically binds to a leczyme. The invention also provides methods to identify a carbohydrate ligand that...
DE69535476T2 Substituted 1,3-oxathiolanes with antviralen properties  
This invention relates to single enantiomers of novel cis-substituted 1,3-oxathiolanes, of formula (I) wherein R1 is hydrogen, and R2 is cytosine or 5-fluorocytosine, and pharmaceutically...
DE69133568T2 Bacteriophage particles which present dAbs  
A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are...
DE60219653T2 PHARMACEUTICAL COMPOSITION WITH CHITO-OLIGOMERS  
Compositions are provided comprising chito-oligomers obtainable from chitin, comprising oligomers of N-acetyl glucosamine (NAG) and glucosamine, wherein at least 50% of the oligomers have a chain...
DE60128002T2 RECEPTOR NUCLEIC AND RECEPTOR POLYPEPTIDES  
Disclosed are nucleic acids encoding BAFF-R polypeptides, as well as antibodies to BAFF-R polypeptides and pharmaceutical compositions including same. Methods of treating tumorigenic and...
DE3890998B4 Neutrophilenaktivierungsfaktor, process for its preparation and pharmaceutical composition containing it  
Neutrophil-activating factor (NAF) is claimed. More specifically it has the qiven complete amino acid sequence. Also claimed is DNA having the nucleotide sequence indicated and equivalents...
DE69935828T2 Alkaline ceramidase (EC 3.5.1.23) coding gene from Pseudomonas aeruginosa  
Ceramidase of Pseudomonas aeruginosa AN17 isolated from the skin of a patient with atopic dermatitis. Gene encoding for such a ceramidase and their variants. Probes or primer hybridizing with the...
DE60219652T2 Chromogenic in situ hybridization METHOD, KITS AND COMPOSITIONS  
The present invention relates to chromogenic (calorimetric) in situ hybridization (CISH) and nucleic acid probes useful for in situ hybridization. Specifically, the present invention provides...
DE602004006153T2 CRYSTAL CONNECTION OF 4'-demethyl-4'-PHOSPHATE-2 ', 3' '- BISPENTAFLUORPHENOXYiACETYL-4' ', 6' '- ethylidene-.beta.-D-EPIPODOiPHYLLOTOXINiGLUKOSID EITHER IN FREE FORM OR solvated with ETHANOL  
Crystalline epipodophyllotoxin 4'-demethyl-4'-phosphate 2'',3''-bis-(pentafluorophenoxyacetyl)-4'',6''-ethylidene-be ta -D-glucoside (I), as free base or hemiethanolate, is new. Crystalline...
DE60128093T2 INTERFERON-LIKE PROTEIN Zcyto21  
The present invention relates to polynucleotide and polypeptide molecules for Zcyto21, an interferon-like protein, which is most closely related to interferon-± at the amino acid sequence level....
DE102006029306A1 Silylation of polysaccharide, especially cellulose, to give products for use in the textiles, food, building and paint industries, involves dissolving in ionic liquid and reacting with a silylating agent  
A method for the silylation of poly-, oligo- or di-saccharides or their derivatives involves dissolving these compounds in ionic liquid(s) and reacting them with a silylating agent.
DE69819150T3 IMMUNE STIMULATING OLIGONUCLEOTIDE, COMPOSITIONS THEREOF, AND METHOD FOR USE THEREOF  
The invention relates to oligonucleotides which comprise a hexameric nucleotide sequence of the formula 5'-Purine-Purine-[Y]-[Z]-Pyrimidine-Pyrimidine-3' or 5'...
DE60316189T2 P153- P156 AND ANTIGENS FOR DIAGNOSIS OF IMMUNE Ehrlichiosis in Dogs AND HUMAN AND USES THEREOF  
Sequences encoding two immunoreactive glycoproteins were cloned from Ehrlichia canis (p153 gene) and Ehrlichia chaffeensis (p156 gene). These two glycoproteins are species-specific immunoreactive...
DE60034354T2 COMPOUNDS FOR THE PROTECTION OF HYDROXYL AND ITS APPLICATION  
A hydrocarbyldithiomethyl-modified compound of the Formula: R1-O-CH2-S-S-R2 or a salt thereof wherein R1 is an organic molecule and R2 is a hydrocarbyl is useful for protecting and/or blocking...
DE102006028165A1 A process for the acylation of cellulose  
The This invention describes a method for the acylation of Poly-, oligo- or disaccharides or derivatives thereof, by this in an ionic liquid triggers and reacted with a ketene, and new acylated...
DE102004047722B4 A method for isolating and separating carbohydrates from aqueous media and use of ionic liquids for the extraction of carbohydrates  
The invention relates to a method for isolating and separating carbohydrates, especially monosaccharides, disaccharides and/or oligosaccharides, from aqueous media, which is characterized by...
DE69637018T2 METHOD FOR DIAGNOSIS OF hereditary hemochromatosis  
New genetic markers for the presence of a mutation in the common hereditary hemochromatosis (HH) gene are disclosed. The multiplicity of markers permits definition of genotypes characteristic of...
DE60127561T2 PHAGE DEPENDENT SUPER PRODUCTION OF BIOLOGICALLY ACTIVE PROTEIN AND PEPTIDES  
This invention relates to a method for enhancing the production of biologically active proteins and peptides in bacterial cells by infecting bacterial cells of the producer strain, which contain a...
DE60127140T2 Amphotericin B CONTAINING STRUCTURED EMULSION  
Parenteral compositions of oil-coated-Amphotericin B in structured-emulsion form, having LD50 of at least 400 mg/kg in mice and process for making the same have been described. The process...
DE19758788B4 Stereo-selective hydrogenation of sugars to sugar alcohols with good purity - in aqueous solution, at high temperature and pressure, uses catalyst mixture of Raney metal and its alloy with inert core and active shell  
Hydrogenation of 1 or more sugars to sugar alcohols in aqueous solution comprises using hydrogen (H2) at elevated temperature and pressure and a catalyst with an inert core and catalytically...
DE69934998T2 ANTISENSE MODULATION OF EXPRESSION OF ALPHA 4 INTEGRIN  
Compositions and methods are provided for modulating the expression of integrin alpha 4. Antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding integrin...
DE69434885T2 Allergenic proteins and peptides from dust mites and their uses  
Isolated nucleic acids encoding allergens of the species Dermatophagoides pteronyssinus and Dermatophagoides farinae, Der p VII and Der f VII, respectively, are disclosed. A cDNA encoding a...
DE60218891T2 SACCHARIDE-CONTAINING FUNCTIONAL ORGANOPOLYCARBOSILOXANE AND METHOD FOR PRODUCING  
A saccharide residue-functional organopolycarbosiloxane containing at least two monosaccharide or polysaccharide groups per molecule in which a specific site on the monosaccharide or...
DE60218710T2 GEN AND PROTEIN TO RELATED hepatocellular carcinoma  
The present invention provides a novel human gene ZNFN3A1 whose expression is markedly elevated in a great majority of HCCs compared to corresponding non-cancerous liver tissues. The gene encodes...
DE102006025154A1 Mutated DNA polymerase with increased reverse transcriptase activity  
The This invention relates to a DNA polymerase with increased reverse Transcriptase activity, which compared to the wild-type variant at least one mutation in their amino acid sequence comprises,...
DE102006025153A1 Mutant DNA polymerases with higher selectivity  
The This invention relates to a DNA polymerase with increased mismatch discrimination, which compared to the wild-type variant at least one mutation in their amino acid sequence comprises, as well...
DE69935597T2 METHOD FOR PRODUCING SELBSTINDUZIERENDER SYNTHASE  
Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also...
DE69935513T2 ANTIBACTERIAL COMPOUNDS  
Compounds of formulae (XI), (XII), (XIV), (XV) and (XVI), as well as amide derivatives of compounds of formula (XIII), described herein, can be obtained from the cultivation products of a strain...
DE69434940T2 1,2-dioxetanes with improved chemiluminescence  
Novel 1,2-dioxetanes with improved chemiluminescent properties, such as signal intensity, S/N ratio, T½, -etc. are provided by spiroadamantyl 1,2-dioxetanes, wherein the remaining carbon atom of...
DE60312128T2 A method for immobilizing a biomolecule on a support  
Fixing a biomolecule to a synthetic or natural resin-made carrier, comprising spotting a solution of biomolecules onto the carrier and irradiation with ultra-violet rays, is new. An independent...
DE60218840T2 Not alloyed core-shell nanoparticles  
The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle...
DE602004005502T2 COMT INHIBITORS  
The present invention relates to compounds of formula I wherein R1 is as defined in the specification and to esters thereof which are hydrolyzable under physiological conditions and to the...
DE60126482T2 Single chain antibodies AGAINST P53 MUTANT  
More than 90% of mutations found in the p53 protein produce a conformational change in p53 which results in the exposure of an epitope, which is otherwise hidden in the hydrophobic core of the...
DE60033927T2 L-RIBO-LNA ANALOG  
Provided are L-ribo bicyclic nucleotide compounds as well as syntheses of such compounds. The nucleoside compounds of the invention are useful in forming oligonucleotides that can produce...
DE69837007T2 USE OF 9A-azalides AS ANTIMICROBIAL AGENTS FOR ANIMAL  
9a-Azalides are useful in the treatment and prevention of bacterial respiratory and enteric infections in livestock animals, particularly in cattle and swine.
DE69636937T2 BY TRANS-CLEAVAGE GOT THERAPEUTIC molecules  
The molecules and methods of the present invention provide a means for in vivo production of a therapeutic molecule in a selected subset of cells. The pre-therapeutic molecules of the invention...
DE60311649T2 C-aryl glucosides SGLT2 inhibitors and method  
An SGLT2 inhibiting compound is provided having the formula A method is also provided for treating diabetes and related diseases employing an SGLT2 inhibiting amount of the above compound alone or...
DE60220024T2 PYRIMIDINNUKLEOSIDDERIVATKRISTALL  
The present invention provides crystalline forms of a pyrimidine nucleoside derivative having excellent anti-tumour activity. ÄSolutionÜ Crystalline forms of compound of the following formula (I):
DE60218503T2 USE OF PEPTIDE VECTORS TO IMPROVE THE IMMUNE RESPONSE AGAINST ANTIGENS  
The invention relates to conjugates of an antigen coupled to a linear derivative of a beta-stranded antibiotic peptide, which are useful for immunogenic agents to enhance a CTL response. Two...
DE60218165T2 Lipolysis for reducing body weight and medical application  
New lipolysis accelerator comprises a dihydroxyphenyl derivative (I). New lipolysis accelerator comprises a dihydroxyphenyl derivative of formula (I); [Image] Z : CHOHCH 3or COCH 3; R 1, R 2H or...
DE602004007662T2 RAPAMYCIN-carbohydrate DERIVATIVES  
This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin...
DE602004006133T2 NEW GALACTOOLIGOSACCHARIDZUSAMMENSETZUNG AND PREPARATION THEREOF  
Novel strains of Bifidobacterium hifidum capable of producing a novel galactosidase enzyme activity that converts lactose to a novel mixture of galactooligosaccharides. The mixture of...
DE69837295T2 Succinic acid ester of probucol for inhibiting the expression of VCAM-1  
This invention is in the area of methods and compositions for the inhibition of the expression of VCAM-1 and, in particular, for the treatment of diseases mediated by VCAM-1, including...
DE69736637T2 MULTIPLEX AMPLIFICATION SHORT TANDEM REPEAT LOCI  
The invention is directed to the simultaneous amplification of multiple distinct genetic loci using PCR or other amplification systems to determine in one multiplex reaction the alleles of each of...
DE69535405T2 Angiostatin AND METHOD FOR USE FOR THE AVOIDANCE OF ANGIOGENESIS  
The present invention comprises an endothelial inhibitor and method of use therefor. The endothelial inhibitor is a protein isolated from the blood or urine that is eluted as a single peak from...
DE69535365T2 PARALLEL SELEX METHOD  
This invention disclosures a method for coevolving products from two or more reactants, along with the nucleic acid that can facilitate the reaction for making the products. The invention further...
DE69434908T2 RECEPTOR ON THE SURFACE OF ACTIVATED T CELLS: ACT4  
The invention provides purified ACT-4 receptor polypeptides, antibodies against these polypeptides and nucleic acids encoding ACT-4 receptor polypeptides. Also provided are methods of diagnosis...
DE69233676T2 Receptor protein tyrosine kinase (FLK-1)  
isolated mammalian nucleic acid molecules encoding receptor protein tyrosine kinase expressed in primitive hematopoietic cells and not expressed in mature hemotopoietic cells are provided. Also...