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DE10247476B4 A method for concentrating and isolating Oregonin  
process for enrichment and isolation of Oregonin of formula I alder bark by extraction in 50-120 ° C hot water, Filtration, selective deposition of the overnight cooled extract acrylate-adsorber,...
DE10328813A1 Method for investigating cytosine methylation in DNA sequences by means triplexbildender oligomers  
It is a method for examination of locations of cytosine methylations in DNA sequences described. It triplex oligomers are used, the preferred in positions triplex structures form at which cytosine...
DE10106370B4 Oligonucleotide probes for the detection of periodontal bacteria by means of in situ hybridization  
oligonucleotide probes for species-specific detection of periodontal pathogenic bacteria of the species Actinobacillus actinomycetemcomitans by in situ hybridization, wherein the oligonucleotide...
DE10329240A1 Method for analysis of cytosine methylation status of Cancer-testis antigens for an individualized immunotherapy  
described is a method for determining the points of a tumor immunotherapy, said method comprising:a) removes a DNA sample,b) the methylation state at least each of a CpG position within more...
DE10325200A1 Preparation of saccharide esters  
It is provided a process for the preparation of saccharide esters by reacting saccharides with activated carboxylic acids in an aprotic dipolar solvent and described in the absence of a basic...
DE102004028318A1 Preparation of aldoses  
A Aldose having n-1 carbon atoms is from an aldonic acid with n carbon atoms using hypochlorous acid or a hypochlorite with a high yield and safely and at a low cost by treating the reaction...
DE19747642B4 A process for producing isomelezitose-containing sweeteners, of isomelezitose and isomaltulose  
process for the preparation of a sweetener, being enzymatically in a first method step saccharose converting at a temperature of 50 to 60 ° C and in a second Step the Saccharidgemisch obtained...
DE19624345B4 Acylated carbohydrates with at least one etherified with the carbohydrate carboxyalkyl group, processes for their preparation and their use in detergents  
Acylated etherified carbohydrates having at least one with the carbohydrate Carboxyalkyl group of the general formula KH (-O-CHR1COOH)n (-O-CO-R2)m in the KH (carbohydrate) is a monosaccharide,...
DE10324063A1 Preparing nucleotides on controlled pore glass, useful for making libraries for screening to identify aptamers, by coupling protected deoxyphosphoramidite directly to amino groups on the glass  
Preparing nucleotides (I) bound to porous glass (controlled pore glass; CPG) comprising functionalizing the surface of CPG with amino groups; coupling a protected deoxyphosphoramidite (I) directly...
DE29724846U1 Preparation of 6-O-methyl erythromycin A crystal Form II - from erythromycin, treating with solvent, and isolating, useful as an antibiotic  
Preparation of 6-O-methylerythromycin A crystal form II comprising: (a) converting erythromycin A to 6-O-methylerythromycin A; (b) treating 6-O-methylerythromycin A with a solvent selected from...
DE10319917A1 Process for the selective carbohydrate oxidation using a supported gold catalysts  
The This invention relates to a process for the selective oxidation a carbohydrate in the presence of a gold catalyst, the distributed nanodispersed Gold particles comprises on a metal oxide...
DE10320070A1 Water-soluble or water-based polymers of monoethylenically unsaturated saccharide  
Water-soluble or water-based polymers of monoethylenically unsaturated Saccharide, the(A) 5 to 100 wt .-% of at least one Ester selected from the group of Monoacrylsäure- and monomethacrylic of...
DE10320519A1 A method for detecting infectious (+) - strand RNA viruses, in particular infectious enterovirus  
It A method for detecting infectious (+) - strand RNA viruses, in particular Enteroviruses, described in a sample. In this case, first a Cell culture with the sample inoculated, then the...
DE19545870B4 A process for the preparation of the (meth) acrylic acid esters of carbohydrates  
process acrylic acid esters for the preparation of (meth) carbohydrates with at least one free hydroxyl group in molecule selected from the group consisting of sucrose, sugar alcohols and...
DE10316701A1 New nucleic acid, and derived proteins, useful for diagnosis of bronchial cancer and in screening for therapeutic and diagnostic agents  
Isolated nucleic acid (I) associated with bronchial cancer comprising 489 defined sequences given in the specification, is new. Independent claims are also included for: (1) protein or peptide...
DE10315772A1 Chemical compounds and methods for the intramolecular energy transfer to the elimination of labile functional groups of chemical compounds  
The present invention provided a chemical compound and a A process for the elimination of labile functional groups of molecules by the action of electromagnetic radiation using the chemical...
DE10316268A1 Extraction of 2-keto-L-gulonic acid from a polar solvent comprises extraction of the acid from the polar, preferably aqueous solvent with an extracting agent containing a tertiary amine and a polar organic diluent  
Extraction of 2-keto-L-gulonic acid (I) from a polar solvent comprises extraction of (I) from the polar, preferably aqueous solvent with an extracting agent containing a tertiary amine and a polar...
DE19720496B4 A process for hydrogenating sugars or sugar mixtures to sugar alcohols or sugar alcohol mixtures  
process for hydrogenating sugars or sugar mixtures to sugar alcohols or sugar alcohol mixtures wherein the sugars are ketoses or contained and selected the sugar mixtures ketoses are from the...
DE202004012163U1 System for hybridizing immobilized nucleic acid samples, in sealed hybridizing chambers, has a pressure assembly to build up the chamber pressures over ambient atmospheric levels to prevent the formation of air bubbles  
A system (1) with hybridizing chambers (5), to hybridize immobilized specimens on carriers (27), having chambers which are defined by the gap between the carrier and a cover (26), and which can be...
DE10313791A1 Specific detection of mycobacteria of the M. tuberculosis complex  
Methods and means for the specific detection of mycobacteria of the Mycobacterium tuberculosis complex (TBC), particularly Mycobacterium tuberculosis, Mycobacterium bovis, Mycobacterium bovis BCG...
DE10312775A1 Microbial production of L-alanine, using microorganisms in which catabolism of pyruvate has been switched off and a gene for L-alanine dehydrogenase has been introduced  
Microbial production of L-alanine comprises anaerobic fermentation of a genetically modified microorganism (A) in which (a) catabolic reactions that start from pyruvate have been switched off and...
DE10005808B4 Process for the preparation of template DNA from refined vegetable food which is suitable for amplifying a region of DNA by the PCR method  
A process for the preparation of a template DNA of a grafted plants food, which was subjected to protein denaturation, comprising the steps of: (A) carrying out a degreasing treatment of the...
DE20220947U1 New pyrrolo(2,3-d)pyrimidine nucleoside analogs useful as immunomodulators for treatment of cancer and autoimmune diseases  
Pyrrolo(2,3-d)pyrimidine nucleoside analogs (I), their salts or prodrugs, are new. Pyrrolo(2,3-d)pyrimidine nucleoside analogs of formula (I), their salts or prodrugs, are new: [Image] A : O, S or...
DE10312625A1 Method for preparing functional peptide nucleic acids, useful e.g. in gene therapy and as detection probes, using protected synthon that allows subsequent reaction with functional carboxylic acid  
Method for producing a functional PNA (peptide nucleic acid) oligomer (A) in which PNA monomer units, containing protected adenine, guanine, cytosine or thymidine, are reacted with Fmoc-omega...
DE10310267A1 Intramolecular transesterification of material, especially plant extract, containing cyclic polyhydroxy compounds, e.g. to prepare bioactive natural products, carried out at elevated temperature and pressure  
Intramolecular transesterification of starting materials containing cyclic polyhydroxy compounds (e.g. phenylethanoids) is carried out at a pressure of 1-20 x 103> Pascals and a temperature of...
DE10308941A1 Monofunctional perylenetetracarboxylic acid bisimides  
The invention relates to novel Perylentetracarbonsäurebisimid derivatives with improved application properties.
DE10308931A1 System and process for the synthesis of polymers  
The present invention relates to an automated polymer synthesis apparatus for synthesis of a polymer chain onto a solid substrate by sequentially adding Polymerbaublöcken and a method for...
DE10012540B4 Oligonucleotides and methods for the specific detection of micro-organisms by the polymerase chain reaction  
Oligonucleotide comprising a sequence selected from the group consisting of: a) 5'-TTA TAC GAC AAA ACT GCA GT-3 '; b) 5'-ATT CGT ATT AGT ATT GTT TGA TG-3 '; c) 5'-ACT ACT AAC AAC AAT ACA GC-3 ';...
DE202004006675U1 Apparatus to purify and isolate nucleic acids, for diagnosis from small samples taken from e.g. blood, has two interconnected hollow bodies with a nucleic acid bonding material at the inlet to the second body  
The apparatus to purify or isolate nucleic acids has a hollow body (100) with an inlet opening (101) for a sample, and an outlet opening (102). A second hollow body (200) has an inlet opening...
DE10310082A1 Protein-binding doxorubicin-peptide derivatives  
The invention relates to low molecular weight doxorubicin-peptide derivatives with MMP-2 or MMP-9 cleavable peptide sequences that contain a protein-binding group.
DE10119203B4 A process for the production of double stranded nucleic acids with single-stranded overhangs of arbitrary length and nucleotide composition  
A process for the production of deoxyribonucleic acid (DNA) by one or two 5 'protruding ends, characterized in that a DNA synthesis with one or two polymerase resistant oligonucleotides is carried...
DE10309682A1 New 1-chloro-5-methylene-7-hydroxy-9,9-dimethyl-spiro(5.5)undec-2-enes useful as antibiotics for treating infectious diseases and for preventing transmission of staphylococcal infections in cattle  
1-Chloro-5-methylene-7-hydroxy-9,9-dimethyl-spiro[5.5]undec- 2-enes (I) are new. 1-Chloro-5-methylene-7-hydroxy-9,9-dimethyl-spiro[5.5]undec- 2-enes of formula (I) are new. [Image] R1>H, acetyl,...
DE10308850A1 Preparation of conjugated polyunsaturated fatty acids, useful in nutrition, cosmetics and pharmaceuticals, comprises expressing specific isomerases in eukaryotic, particularly plant, cells  
Preparation of conjugated polyunsaturated fatty acids (I), having at least two double bonds, in transgenic eukaryotic organisms comprises expressing a specific nucleic acid (II) in an organism...
DE10226702A1 Antisense oligonucleotides against PIM1  
The invention relates to antisense oligodeoxynucleotides against PIM1, corresponding nucleotide constructs containing these cells, drugs and diagnostic agents, their use in the treatment of pain...
DE10258007A1 New aromatic Fluorglycosidderivate, pharmaceutical compositions containing them and their use  
The invention relates to substituted aromatic Fluorglycosidderivate of the formula I, wherein the radicals have the meanings indicated, and their physiologically acceptable salts and processes for...
DE10307732A1 New oligonucleotides for specific detection of microorganisms, useful e.g. for detecting or quantifying microbes on the skin, in foods, clinical samples or water, by in situ hybridization  
Oligonucleotides (ON) for specific detection of microorganisms, are (i) are any of 30 sequences reproduced; (ii) have at least 80, best 95, % correspondence with (i); (iii) are derived from (i) or...
DE10303973A1 A method for detection of fertility enhancing or contraceptive agents  
The present invention relates to a method for the detection of changes of cellular messengers in sperms in a stopped-flow measurement apparatus or detecting the motility or the change in swimming...
DE4120345C5 Protein fragments from the central region of the flagellin of Borrelia burgdorferi, as antigens suitable for the specific detection of antibodies as well as methods for their preparation  
Protein fragment from the middle region (amino acid 132 to amino acid 266) of flagellin of Borrelia burgdorferi, characterized in that it consists of the amino acid sequence consists.
DE10303850A1 Screening assay based on the Forkhead transcription factor-dependent SOD-3 promoter used to identify AKT modulating compounds or of upstream regulators, such as insulin / IGF1 receptors  
The present invention relates to the identification and use of the reactant to DAF-2 / IR sod-3 promoter. It describes transgenic C. elegans with sod-3-reporter gene constructs, which are suitable...
DE10303664A1 Recognition molecules for the treatment and detection of tumors  
The invention relates to recognition molecules, which are directed against tumors, pharmaceutical compositions comprising said recognition molecules, method for production of the recognition...
DE10302421A1 New double-stranded interfering RNA, useful for inhibiting hepatitis C virus, has one strand linked to a lipophilic group to improve activity and eliminate the need for transfection auxiliaries  
Double-stranded RNA (I) having a strand (S1) that is complementary, at least in parts, to a target gene (TG) and, the new feature, linked to at least one lipophilic group (A) is new. An...
DE10301519A1 New substituted 9-keto-spinosyn derivatives, useful for control of animal pests and microorganisms, in plant protection and veterinary medicine, also new intermediates  
9-substituted keto-spinosyn derivatives (I) and their salts are new. 9-substituted keto-spinosyn derivatives of formula (I) and their salts are new. X = oxygen, NH or NR4; R1 = hydrogen or an...
DE19823876B4 With different compounds laden component (biochip) as well as methods for its preparation  
Component (biochip) for the detection of substances by their specific spatial addition, the surface of which is loaded in spatially separated regions with different compounds, especially...
DE10260805A1 Method and apparatus for optimizing a nucleotide sequence for expressing a protein  
The invention relates to a method for optimizing a nucleotide sequence for expressing a protein on the basis of the amino acid sequence of the protein, wherein for a specific area, a test sequence...
DE4325471B4 Valve system for the simultaneous synthesis of DNA or peptide sequences  
Valve system comprising a) a valve block (10) having a plurality of feed channels formed within the same (31), b) a plurality of delivery channels (36) extending transversely to the feed channels...
DE10300049A1 New compounds which inhibit factor VIIa  
The present invention relates to novel compounds of formula (I): These compounds are very potent factor VIIa inhibitors and are therefore especially in the treatment and / or prevention of...
DE10261693A1 Production of new or known monomeric uronic acid compounds, useful e.g. as immunosuppressive or antiarthritic agents, by hydrolyzing bacterially produced polyuronic acid  
Production of monomeric uronic acids (or their derivatives) (I) involves (a) fermenting a bacterial strain producing a polyuronic acid (II) formed from (I) units, (b) isolating (II) from the...
DE10232774B4 Cosmetic preparations with antibacterial properties  
Cosmetic preparations, characterized in that it comprises an effective amount of (A) glycyrrhetic acid zinc salt and (B) benzoyl contain.
DE10259714A1 Method for identifying the polled genotype in cattle, useful in breeding programs, comprises detecting any of seven new microsatellite markers, also new oligonucleotides  
Identifying the polled (hornless) genotype of cattle comprising analyzing DNA for at least one of the genotype-associated microsatellite markers 59A3-A3r, -CSfa, -CSfb, -D3f, -D5f, -D8f, or -F8r...
DE10259713A1 A method for expressing stabilization and improvement of specific effector function of single-chain antigen knower genetic constructs (scARC) and corresponding mutant MDM2 protein specific SCT-cell receptors  
The present invention relates to a process for preparing stabilized single chain antigen recognized genetic constructs (scARC), in which in addition to the conventional V1/2-Li-V2/1-C4/3-sc...