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DE69637153T2 IMPROVEMENTS IN OR RELATING TO PFANZENSTÄRKEVERBINDUNGEN  
Disclosed is a nucleotide sequence encoding an effective portion of a class A starch branching enzyme (SBE) obtainable from potato plants, or a functional equivalent thereof, together with, inter...
DE69434988T2 Tumor necrosis FACTOR GAMMA  
A human TNF-gamma polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for...
DE69434926T2 HUMAN tissue inhibitor of metalloproteinase-4  
A human tissue inhibitor of metalloproteinases-4 polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques. Also disclosed are...
DE68929551T2 Human DNase  
DNA isolates coding for human DNase and methods of obtaining such DNA are provided, together with expression systems for recombinant production of human DNase useful in therapeutic or diagnostic...
DE60220719T2 ANTIBODY AGAINST THE MUC18 ANTIGEN  
The present invention relates generally to the generation and characterization of anti-MUC18 monoclonal antibodies. The invention further relates to the use of such anti-MUC18 antibodies in the...
DE60220713T2 Ribofuranosyluronamide derivatives as crystal; a human adenosine A2A receptor Agonsit  
The present invention relates to a crystalline form of 6-[(2,2-diphenylethyl)amino]-9-(N-ethyl-beta-D-ribofuranosyl uronamide)-N-(2-{N'-[1-(2-pyridyl)-4-piperidyl]ureido}ethyl) -9H-purine-2-carboxa...
DE102006039479A1 Programmable oligonucleotide  
The Invention relates to methods and apparatus for the preparation of synthetic nucleic acids.
DE602004007184T2 Means and methods for diagnosis and treatment of affective disorders  
The present invention relates to nucleic acid molecules, preferably genomic sequences, encoding an ATP-gated ion channel P2X7R which contain a mutation in the 5'UTR or 3'UTR regions, a mutation in...
DE60128950T2 Immunomodulatory protein derived from the Yaba Monkey Tumor Virus  
The invention generally features the use of Yaba monkey tumor virus nucleic acid molecules and polypeptides for the treatment or prevention of immune-related diseases.
DE10066210B4 Use of perfluoroalkyl-metal complexes as contrast agents in MR imaging for displaying plaques  
The invention relates to the use of metal complexes containing perfluoroalkyl, comprising a critical micelle formation concentration < 10<-3> mol/l, a hydrodynamic micelle dynameter of (2 Rh) > 1...
DE69836384T2 Antisense oligonucleotides AGAINST thymidylate  
Antisene oligonucleotides targeted to sequences in thymidylate synthase (TS) mRNA. In particular the invention relates to antisense oligonucleotides targeted to sequences in the 3' end of TS mRNA,...
DE69535519T2 ON YEAST-BASED VEHICLE FOR RELEASE  
The present invention includes yeast vehicles and their use as delivery vehicles. Yeast vehicles include a yeast portion and a heterologous compound. Such yeast vehicles can be used to protect...
DE69434985T2 IMMUNOGENIC COMPOSITIONS AGAINST the infection of Helicobacter, USE OF POLYPEPTIDES IN THESE COMPOSITIONS AND NUCLEIC THE SAID POLYPEPTIDES CODE  
There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises:i) at least one sub-unit of a urease...
DE602005001331T2 Adsorption of nucleic acids to a solid phase  
The present invention is directed to a method for adsorbing, i.e. non-covalently binding, nucleic acids to a solid phase using a two-step procedure. Furthermore, the present invention pertains to...
DE102007007750A1 avermectin  
New Avermectin derivatives of the formula (I), in which -C22R1-AC23R2. R3, R4 and R5 the meanings indicated in the description have,Methods for preparing these substances and their use for...
DE102006037580A1 Sandel Perfume receptors  
The Invention relates to the field of olfactory receptors, the receptive influencing Medications and biosensors. The invention further relates to compounds of the general formula (I), in whichX...
DE69936315T2 FRAGMENTS OF THE GROWTH FACTOR FOR CONNECTIVE TISSUE (CTGF) AND METHOD AND USES THEREOF  
The present invention is directed to CTGF fragments comprising at least exon 2 or exon 3 of CTGF and having the ability to induce extracellular matrix synthesis, in particular, collagen synthesis...
DE69935327T2 ENDONUCLEASE FOR DNA DAMAGE WITH BROAD SPECIFICITY  
The present disclosure describes DNA damage endonucleases which exhibit broad specificity with respect to the types of structural aberrations in double stranded DNA. These enzymes recognize double...
DE69637123T2 THE EXPRESSION OF CYCLIN G1 IN TUMORS  
A method of treating a tumor (in particular osteosarcoma or Ewing's sarcoma) in a host by administering to a host or to the tumor cells an agent which inhibits cyclin G1 protein in an amount...
DE602004006831T2 CLEANING POLYPEPTIDES  
A method for purifying a desired heterologous polypeptide from microbial fermentation broth or homogenate in which it is produced and solubilized is described. This method involves adding to the...
DE102006037581A1 Citrusal Perfume receptors  
The Invention relates to the field of olfactory receptors, the empfängsnisbeeinflussenden Medications and biosensors.
DE69911935T3 GRANULATIMIDE DERIVATIVES FOR THE TREATMENT OF CANCER  
Novel granulatimide compounds and pharmaceutical formulations thereof are provided. Compounds of this invention have general formula (I) or (II) wherein are independently R or Z as defined below,...
DE69802191T3 Solid phase nucleic acid isolation  
The present invention provides a method of isolating nucleic acid from a sample of cells, said method comprising: (a) binding cells in said sample in a solid support to isolate cells from the...
DE60128900T2 GROUND MARKER  
A set of two or more mass labels, each label in the set comprising a mass marker moiety attached via a cleavable linker to a mass normalisation moiety, the mass marker moiety being fragmentation...
DE102006035618A1 New nucleic acid useful as immuno-stimulating adjuvant for manufacture of a composition for treatment of cancer diseases e.g. colon carcinomas and infectious diseases e.g. influenza and malaria  
Nucleic acid (I) is new. Nucleic acid of formula G lX mG n (I) is new. G = guanosine, uracil or an analog; X = guanosine, uracil, adenosine, thymidine, cytosine or an analog; l = 1-40; m >= 3; and...
DE69936141T2 USE OF DNA-PK  
This invention provides a method for increasing the susceptibility of a cell to DNA-damaging agents, comprising introducing into the cell an antisense oligonucleotide that specifically hybridizes...
DE69837806T2 "DEATH DOMAIN" -containing Receptor 4 (DR4), A MEMBER OF TNF RECEPTOR SUPER FAMILY WHAT TO TRAIL (APO-2L) TIES  
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid...
DE69535358T2 Haemophilus influenzae ADHERENCE AND PENATRATIONSPROTEINE  
Haemophilus adhesion and penetration proteins, nucleic acids, vaccines and monoclonal antibodies are provided.
DE69334146T2 PEPTIDES WITH GDP EXCHANGE FACTOR SIMILAR EFFECT THEREOF Nucleic acid sequences encoding, THEIR PRODUCTION AND USE  
PCT No. PCT/FR93/00382 Sec. 371 Date Oct. 19, 1994 Sec. 102(e) Date Oct. 19, 1994 PCT Filed Apr. 19, 1993 PCT Pub. No. WO93/21314 PCT Pub. Date Oct. 28, 1993The present invention relates to...
DE60221227T2 Xanthan gum containing reepithelialisierende pharmaceutical preparations  
The present invention relates to the use of xanthan gum as re-epithelializing agent and, in particular, to a pharmaceutical formulation comprising xanthan gum as a re-epithelializing active...
DE60219620T2 L-ascorbic acid 2-O-MALEIC ACID-A-TOCOPHEROLDIESTER-1-PROPANOL ADDUCT AND METHOD FOR PRODUCING  
The present invention provides a novel industrially excellent and ecological process for producing methylcobalamin which is useful as a medicament etc. More specifically, it provides a process for...
DE602004006599T2 Compounds for hydrolysis of ribonucleic acids (RNA)  
The present invention relates to a method and compounds for hydrolysing nucleic acids. In particular it relates to compounds that can be used for the preferential cleavage of a phosphodiester bond...
DE69434980T2 Stable bactericidal proteins, which increase the permeability and pharmaceutical compositions containing them  
Disclosed are novel bactericidal/permeability-increasing (BPI) protein products wherein cysteine residue number 132 or 135 is replaced by another amino acid residue, preferably an alanine or...
DE69233695T2 Genetically engineered glutaminase AND THEIR USE IN THERAPY  
DNA encoding a therapeutically suitable glutaminase has been molecularly cloned. This allows one to obtain a polypeptide which is a therapeutically suitable glutaminase free of contaminating...
DE60314123T2 Selective oxidation WITH INCREASED SECURITY  
A safe and effective process for the oxidation of a primary or secondary alcohol to the corresponding aldehyde or ketone via the reaction of said alcohol with an anhydride solution of a...
DE60313993T2 METHOD FOR PHOSPHITHYLIERUNG  
A process for the phosphitylation of an alcohol or thiol with a phosphitylation agent in the presence of an activator is provided. The activator has the formula: wherein p is 0 or an integer from...
DE69935323T2 Moraxella Catharralis PROTEINS  
Novel antigens of B. catarrhalis are provided, together with their use in vaccines as well as methods of diagnosis and/or detection.
DE69434960T2 Gene therapy for solid tumors, papillomas, warts  
The present invention provides a DNA delivery system for use in a method of treating localized solid tumors and papillomas in an individual, as well as metastatic carcinomas. The method comprises...
DE60220180T2 14 TO 15 LIMBS macrolides WITH ANTIBACTERIAL ACTIVITY  
The present invention relates to 14 or 15 membered macrolides substituted at the 4' position of formula (I) and pharmaceutically acceptable salts and solvates thereof, to processes for their...
DE60220025T2 METHODS AND COMPOSITIONS FOR REPRODUCTION OF RNA SEQUENCES  
The invention provides methods for isothermal amplification of RNA. The methods are particularly suitable for amplifying a plurality of RNA species in a sample. The methods employ a composite...
DE60219922T2 NEW SALTS OF COMPOUNDS WITH ANTI SPASM EFFECT  
The invention relates to novel pharmaceutically acceptable salts of anticonvulsant derivatives, processes for preparation of and pharmaceutical compositions containing said salts, useful in the...
DE60128565T2 POLYCYCLIC XANTHONE AS ANTIBIOTICS  
A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated...
DE102006032569A1 Silylating poly-, oligo-, disaccharides derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent  
Silylating poly-, oligo-, disaccharides or their derivatives comprises dissolving the poly-, oligo- disaccharides in an ionic liquid and reacting the obtained mixture with a silylating agent. An...
DE69935927T2 PLASMID STABILIZATION SYSTEM FOR THE ADMINISTRATION OF ANTIGENES  
The present invention relates generally to a Plasmid Maintenance System for the stabilization of expression plasmids encoding foreign antigens, and methods for making and using the Plasmid...
DE69133552C5 Deoxyribonucleic acid sequence encoding non-A, non-B hepatitis virus - obtd. Hutch C59 subgroup encoding polypeptide(s), useful as vaccines, and immuno reactive ABS for diagnosis of virus  
Sequence (I) comprises (a) the Hutch c59 DNA sequence shown in SEQ ID NO:46 of the spec; (b) degenerate sequences of the sequence of (a); (c) a mutant variant of the NANBV Hutch c59 strain with...
DE602004005826T2 METHODS FOR CLEANING OF STABLE RADIOIODIUM CONJUGATES  
The present invention is directed toward a method for preparing and purifying a conjugate of a radioiodinated aminopolycarboxylate-appended peptide and a targeting agent. The method involves (A)...
DE602004005752T2 NEW DERIVATIVES OF MORPHINE-6-glucuronide, THESE DERIVATIVES pharmaceutical compositions containing, MANUFACTURING AND METHODS OF USE THEREOF  
Morphine-6-glucuronide derivatives (I) and their salts are new. Morphine-6-glucuronide derivatives of formula (I) and their salts are new; [Image] R 1>1-10C linear or branched alkyl, optionally...
DE60128070T2 VACCINE SPECIFICALLY AGAINST KIDNEY TUMORS, directed against the antigen G-250 RENAL TUMOR  
This invention provides an anti-cancer immunogenic agent(s) (e.g. vaccines) that elicit an immune response specifically directed against renal cell cancers expressing a G250 antigenic marker....
DE60032388T2 CRYSTALLINE MIXTURES OF TEILMETHYLETHERN OF BETA-cyclodextrin and RELATED LINKS  
Certain mixtures of cyclodextrin derivatives, which were synthesized in mildly basic conditions, can be separated into mixtures that crystallize easily and mixtures of similar composition, which...
DE19528029B4 Magnetic polymer particles based on polyvinyl alcohol, process for their preparation and use  
Spherically shaped polyvinyl alcohol (PVAL) polymer particles are prepared encapsulating a magnetic colloid that provides the particles with magnetic properties for use in binding biomolecules....