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8884059 |
Electrodepositable coating composition containing a cyclic guanidine
The present invention is directed towards an electrocoating composition comprising a cyclic guanidine. |
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8796491 |
Process for manufacturing adamantane derivatives with high yield
The present invention pertains to process for the amidation of a substituted 1-bromo-adamantane comprising a step (0) of reacting a substituted adamantane with an excess of bromine to obtain a... |
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8772547 |
Method for producing 1-adamantyl trimethylammonium hydroxide
The present invention relates to a process for preparing 1-adamantyltrimethylammonium hydroxide, by A) reacting 1-adamantyldimethylamine with dimethyl sulfate to give 1-adamantyltrimethylammonium... |
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8436209 |
Process for the manufacture of memantine and intermediate product
The present invention relates to a process for manufacturing N-Formyl-1-amino-3,5-dimethyladamantane, an intermediate product in the overall process of producing 1-Amino-3,5-dimethyladamantane... |
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7981930 |
Compositions and kits for treating influenza
Kits comprising an M2 inhibitor selected from amantadine and rimantadine; ribavirin, and a neuraminidase inhibitor (NAi) in an amount that is antivirally effective in the combination, an oral... |
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7902115 |
Adducts of amines and polycarboxylic acids, and filter media comprising such adducts
Herein are disclosed adducts of amines and polycarboxylic acids, and methods of making such adducts. Such adducts can be used to remove cyanogen chloride. Also disclosed are methods of providing... |
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7858660 |
Compositions and kits for treating influenza
Compositions, kits and methods are provided for the treatment or prophylaxis of influenza. |
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7462743 |
Polymorphs of memantine hydrochloride
A crystalline Form II of memantine hydrochloride, pharmaceutical compositions containing crystalline Form II, and methods of preparing crystalline Forms I and II of memantine hydrochloride are... |
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7329759 |
Illudin analogs useful as antitumor agents
The present invention provides illudin analogs of the general formula (I): where R1 is (CH2)n—X—Y or H; n is 0 to 4; X is O or S or N or absent; and Y is an optionally substituted (C1-C8)alkyl,... |
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6444702 |
Aminoadamantane derivatives as therapeutic agents
The present invention provides novel aminoadamantane derivatives, methods of making the derivatives, compositions including the novel aminoadamantane derivatives, and methods for the treatment and... |
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6423871 |
Efficient synthesis of secondary amines by selective alkylation of primary amines
A method for selective mono-N-alkylation of primary amines to produce secondary amines that are substantially free of overalkylated tertiary amines and quaternary ammonium salts, under mild... |
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6114392 |
Agmatine, and polyaminoguanidine-bound heterocyclic compounds for neurotrauma and neurodegenerative diseases
The invention relates to the use of agmatine, in the treatment of acute neurotrauma (such as stroke) and degenerative disorders of the central and peripheral nervous system (such as dementia).The... |
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5912386 |
Bridged anthraquinones
The present invention relates to compounds of the formula (I) R1 --NH--B--NH--R2 (I),wherein R1 and R2 independently of one another denote an unsubstituted or substituted radical of the formula... |
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5719176 |
2-amino-1,3-propanediol compound and immunosuppressant
A 2-amino-1,3-propanediol compound represented by general formula (I) or a pharmaceutically acceptable salt thereof, and an immunosuppressant containing the same as the active ingredient. In said... |
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5609867 |
Polymeric antitumor agents
This invention provides novel antitumor agents having the formula: ##STR1## wherein A, B, G, W, R1, R2, R3, n, m and Z are described in the specification which have activity as anticancer agents... |
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5596020 |
Amino bi- and tri-carbocyclic alkane bis-aryl squalene synthase inhibitors
This invention relates to a class of novel amino bi- and tri-carbocyclic alkane compounds having bis-aryl substitution which exhibit squalene synthase inhibition properties. The bi- and... |
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5576355 |
Diamondoid derivatives for pharmaceutical use
A method of inhibiting viruses in which a virus is contacted with diamondoid alcohol, ketone, ketone derivative, adamantyl amino acid, quaternary salt or combinations thereof which have antiviral... |
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5434274 |
Benz(epsilon)indene compounds
Neuroactive benz[e]indene compounds ##STR1## are prepared by a total synthesis from the following three starting materials ##STR2## |
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5206415 |
Tricyclic steroid analogs
Novel tricyclic steriod analogs are disclosed which are 1H-benz[e]indene dodecahydro compounds that are useful for enhancing GABA-induced chloride currents at the GABA receptor/chloride ionophore... |
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5041673 |
Novel tetralin derivatives
This invention relates to novel derivatives of tetralin, to the processes for their preparation, to their use as aminopeptidase inhibitors and to their end-use application as immunomodulators and... |
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4649222 |
2-(substituted amino)-2-[2-hydroxy-2-alkyl (or phenyl)ethyl]tricyclo[3.3.1.13,7 ]decane hydrohalides
2-(Substituted amino)-2-[2-hydroxy-2-alkyl (or phenyl)ethyl]tricyclo[3.3.1.13,7 ]decane hydrohalides are described such as 2-(2-hydroxyoctyl)-2-(methylamino)-tricyclo[3.3.1.13,7 ]decane... |
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4329522 |
1,3,5,7-Tetranitroadamantane and process for preparing same
The invention provides a novel explosive compound 1,3,5,7-tetranitroadamane, which possesses high explosive energy combined with excellent impact and thermal stability. The novel compound can be... |
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4283422 |
3-Amino-4-homoisotwistane derivatives
Novel 3-amino-4-homoisotwistane derivatives of the formula, ##STR1## wherein R1 is a hydrogen atom, a C1 -C4 alkyl group or a C3 -C5 alkenyl group, and R2 is a C1 -C4 alkyl group or a C3 -C5... |
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4275237 |
Hydrogenated polynitrile mixture useful as an epoxy hardener
Heavy reaction product after separation as by distillation of light reaction product or diadduct from a reaction mixture obtained by reaction of olefinically unsaturated nitriles with monoolefinic... |
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4263226 |
Process for hydrolyzing 5-isothiocyano-5,6-dihydro-dicyclopentadiene
5-Amino-5,6-dihydro-dicyclopentadiene is prepared by reacting 5-isothiocyano-5,6-dihydro-dicyclopentadiene and an aqueous caustic medium at a temperature in excess of the melting point of... |
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4259260 |
Solvent process for hydrolyzing 5-isothiocyano-5,6-dihydrodicyclopentadiene
5-Isothiocyano-5,6-dihydro-dicyclopentadiene is hydrolyzed with caustic to 5-amino-5,6-dihydro-dicyclopentadiene in a reaction medium comprising a polar organic liquid which is inert under the... |
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4254128 |
2-Adamantyl hydrazines and biocidal compositions thereof
The invention provides novel 2-adamantyl hydrazine derivatives of the general formula A ##STR1## In this formula R1 is hydrogen or a lower alkyl group of 1-4 carbon atoms; R2 and R3 are the same... |
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4146559 |
Cycloaliphatic diamines
Compounds are disclosed which correspond to the general formula: ##STR1## in which N AND M WHICH ARE THE SAME OR DIFFERENT HAVE THE VALUES 0, 1 OR 2, R, r1 and R2 which are the same or different,... |
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4122193 |
Drugs or medicines for influencing the central nervous system
Certain 1,3,5-trisubstituted adamantane compounds having central nervous system activity, especially anti-Parkinsonism activity, method of preparing same, and pharmaceutical compositions thereof,... |
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4113726 |
Perhydrofluorenetetrol and perhydrophenanthrenetetrol derivatives
Compounds are provided having the structure ##STR1## wherein n is 1 or 2, n1 is 0, 1 or 2 and n2 is 0, 1, 2 or 3, R1, R2, R3 and R4 may be the same or different and can be hydrogen, lower alkyl,... |
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4104303 |
Acid inhibitor composition and process in hydrofluoric acid chemical cleaning
A Mannich base and thiourea inhibitor composition and method of inhibiting the acid attack by aqueous hydrofluoric acid on ferrous metal surfaces, and in particular, highly reactive ferrous metal... |
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4104305 |
1-Aminotricyclo (4.3.1.12,5) undecane and salts thereof
1-Amino-tricyclo [4.3.1.12,5 ] undecane is prepared by alkaline hydrolysis of 1-acetylamino-tricyclo [4.3.1.12,5 ] undecane, and its acid addition salts are prepared by neutralizing it with an... |
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4101580 |
3-Amino-4-homoisotwistane and an acid addition salt thereof and a process for producing the same
This invention relates to novel 3-amino-4-homoisotwistane (3-amino-tricyclo [5.3.1.03,8 ] undecane), an acid addition salt thereof, and to a process for producing the same. |
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4026946 |
Halogen derivatives of alkynoxymethyl amines
This invention relates to halogen derivatives of alkynoxymethylamines and to uses thereof. The present invention may be ideally illustrated by the following equation: RN(CH2 OR'C.tbd.CH)2 + 2NaOX... |
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4026807 |
Alkynoxymethyl amines
This invention relates to alkynoxymethyl amines, to methods of preparing them, and uses thereof, particularly as corrosion inhibitors. These compounds are prepared by reacting an amine, such as... |
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3894031 |
Indantetrol derivatives
Compounds are provided having the structure ##SPC1## Wherein n is 1,2 or 3, m and m' are 0, 1 or 2, R1, R2, R3 and R4 may be the same or different and can be hydrogen, lower alkyl, halolower... |
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3869506 |
1,2,10-Tricarboxy phenanthrene compounds
Phenanthrene carboxylic acid derivatives useful as anti-inflammatory agents. |
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3867443 |
Nuclear hydrogenation of n-aryl polyamides
N-Alicyclic polyamides are prepared by nuclear hydrogenation of N-aryl polyamides using a metal catalyst. For example bis(4-acetamidophenyl)methane is hydrogenated to... |
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3839460 |
CYCLOPROPENYLIUM SALTS
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3789073 |
ADAMANTYLALKYLAMINOALKYL BENZAMIDES
This invention relates to new adamantylalkyl-aminoalkyl benzamides of the general formula ##SPC1## And to acid addition salts and quaternary ammonium salts of such benzamides, substances which are... |
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3772254 |
ENDO ALICYCLIC END CAPPED POLYIMIDE RESINS
1433891 Unsaturated polyimide prepolymers TRW Inc 21 March 1973 [3 April 1972] 13679/73 Headings C3R and C3P Thermosetting polyimide prepolymers of 2 to 21 mols of an organic carboxylic... |
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3729513 |
TRICYCLO(4.3.1.13,8)UNDECANE-4-ONE
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3717677 |
OXYGENATED 1-AMIDOADAMANTANES
A novel method for the introduction of oxygen into 1-aminoadamantanes by bioconversion to obtain the corresponding oxygenated 1-amidoadamantanes which can be chemically converted to novel... |
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3711553 |
TRICYCLIC KETONES
1,197,168. Tricyclic ketones. F. HOFFMANN-LA ROCHE & CO., A.G. 6 March, 1969 [15 March, 1968], No. 11865/69. Heading C2C. The invention comprises tricyclic ketones of the formula wherein R 1 , R 2... |
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3706801 |
1-AMINOADAMANTAN-4-OLS
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3661896 |
AZATRICYCLIC LACTAMS
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3646095 |
ORGANIC DI-ISOCYANATES OF ALKYLADAMANTANES
1,190,597. Adamantane diisocyanates. SUN OIL CO. 13 Oct., 1967 [20 Oct., 1966], No. 46773/67. Heading C2C. [Also in Division C3] The invention comprises 1,3-diisocyanates of adamantane or of a... |
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3644475 |
PRODUCTION OF ADIPONITRILE
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3595877 |
2-OXA-STEROID AND THE PRODUCTION THEREOF
1,251,025. 2-Oxasteroids. ROUSSELUCLAF. 15 Aug., 1968 [17 Aug., 1967 (2); 7 Dec., 1967; 7 March, 1968], No. 38969/68. Heading C2C. The invention comprises compounds of formula wherein either Z is... |
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3585136 |
CORROSION INHIBITION OF AQUEOUS SOLUTIONS OF INORGANIC MINERAL ACIDS
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