Matches 1 - 50 out of 89 1 2 >


Match Document Document Title
9000047 Compound inhibiting activation of the enzyme Erk 1/2 to be used in the treatment of neurodegenerative illnesses  
The present invention relates to a compound of formula (I) for use as a medicine, in particular for use in the treatment of diseases mediated by the actvation of the protein kinase Erk1/2, such as...
8053603 Tetralone-based monoamine reuptake inhibitors  
The invention relates to novel tetralone based amines and their use in the treatment of central nervous system (CNS) disorders, such as depression, attention deficit hyperactivity disorder (ADHD)...
7981930 Compositions and kits for treating influenza  
Kits comprising an M2 inhibitor selected from amantadine and rimantadine; ribavirin, and a neuraminidase inhibitor (NAi) in an amount that is antivirally effective in the combination, an oral...
7858660 Compositions and kits for treating influenza  
Compositions, kits and methods are provided for the treatment or prophylaxis of influenza.
7582658 Bicyclic compound  
A novel compound represented by the following formula (1) or a salt thereof: wherein symbol “A” represents a saturated heterocyclic group, a 5-membered heteroaromatic group having two heteroatoms...
7342135 3(4),7(8)-Bis(aminomethyl)bicyclo[4.3.0]nonane and a process for its preparation  
3(4),7(8)-bis(aminomethyl)bicyclo[4.3.0]nonane and a process for its preparation, wherein bicyclo[4.3.0]nona-3,7-diene is reacted with synthesis gas in a homogeneous organic phase in the presence...
6262309 Process for producing norbornane dimethylene amines  
Disclosed is a process for producing norbornane dimethylene amines wherein norbornane dicarbonitriles are hydrogenated by using a Raney cobalt catalyst containing manganese etc. in the presence of...
5354901 Perfluoro(cycloaliphatic methyleneoxyalkylene) carbonyl fluorides and derivatives thereof  
Perfluoro(cycloaliphatic methyleneoxyalkylene) compositions are provided. These compositions comprise perfluoro(cycloaliphatic methyleneoxyalkylene) carbonyl fluoride compounds having (a) a...
5232526 Diethanolammoniummethylcubane nitrates hydroxylammonium nitrate (HAN) solutions as aqueous liquid gun propellant ingredients  
This invention is for new compounds, namely, diethanolammoniummethylcubane nitrates, a composition of diethanolammonium methylcubyl nitrates - hydroxylammonium nitrate (HAN) solutions and their...
5232836 Vitamin D derivatives: therapeutic applications and applications to assays of metabolites of vitamin D  
Vitamin D derivatives corresponding to the following formula I ##STR1## in which R1 denotes a substituted alkyl group having 1 to 15 carbon atoms, in particular the side chains of vitamin D2 (C20...
5145874 Cyclic hydrocarbons with an aminoalkyl sidechain  
Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
5093519 Vitamin D derivatives: therapeutic applications and applications to assays of metabolities of vitamin D  
Vitamin D derivatives corresponding to the following formula I ##STR1## in which R1 denotes a substituted alkyl group having 1 to 15 carbon atoms, in particular the side chains of vitamin D2 (C20...
4716248 Aminocyclohexyl-substituted, branch alkylamines  
New compounds having the formula: X--(YQNH2)p Iwherein p is 1 or 2 and the residues QNH2 are the same or different and each is a residue of formula: ##STR1## wherein n is an integer from 1 to 15;...
4551552 Process for preparing rimantadine  
A low temperature and pressure process for preparing rimantadine in high yields from 1-adamantyl methyl ketoxime is provided. The process comprises contacting a solution of the ketoxime with...
4500469 Metal ion control compounds based on norbornane  
The bis(methylamine) of norbornane compounds which have at least one of the amine hydrogens substituted with hydroxyalkyl, methylenephosphonic, alkylenesulfonic, carboxylic acid radicals and salts...
4454157 Antiviral tetracyclononane derivatives, processes for their manufacture and pharmaceutical compositions containing them  
The invention relates to a pharmaceutical composition comprising a tetracyclononane derivative of the formula: ##STR1## wherein R1, R2 and R3 are hydrogen atoms or alkyl radicals and A is CH2 CH2...
4357352 Antiviral tetracyclononane derivatives, processes for their manufacture and pharmaceutical compositions containing them  
The invention relates to a pharmaceutical composition comprising a tetracyclononane derivative of the formula: ##STR1## wherein R1, R2 and R3 are hydrogen atoms or alkyl radicals and A is CH2 CH2...
4229375 1-Aminomethyltricyclo[4.3.1.12,5 ]undecane and acid-addition salts thereof  
1-Aminomethyltricyclo[4.3.1.12,5 ]undecane having the formula (I) and acid-addition salts thereof possess an excellent inhibitory effect on the growth of viruses even at a low concentration. ##STR1##
4229376 Polycyclic polyamines  
Disclosed herein are tricyclic and pentacyclic polyamines having a secondary or tertiary amine group on an amine functional substituent and at least one primary amine group on each of two amine...
4202892 Biocidal methyladamantyl hydrazines and pharmaceutical compositions containing them  
The invention provides novel 1- or 2-adamantylmethyl hydrazines of the general formula A ##STR1## In this formula Ad is 1- or 2-adamantyl, R1 and R2 are the same or different and are each hydrogen...
4177280 Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents  
1-Alkylamino-3-(4-[(endobicyclo[3.1.0]hex-6-yl)alkylure ido]-1-phenoxy)-2-propanol and substituted derivatives thereof; 1-alkylamino-3-(4-[(endobicyclo[3.1.0]hex-6-yl)-alkylcarbony lamino]-1-phen...
4156723 Perhydro naphthalene pentol derivatives  
Compounds are provided having the structure ##STR1## wherein R1, R2, R3 or R4 is hydrogen or acyl, and R5 is hydrogen or acyl, X is a straight or branched bivalent alkylene radical and Y is...
4151194 Dicyanotricyclodecane  
A mixture of 3,8- and 4,8-dicyanotricyclo[5.2.1.0]decane is prepared by the hydrocyanation of 8-cyanotricyclo[5.2.1.0]dec-3-ene in the presence of a catalyst system comprising a zero valent nickel...
4087551 Amino-bicycloheptanes  
Pharmaceutical compositions are described in which the active ingredient is a 7,7-dimethyl-[2,2,1]-bicycloheptane having at the 1-position a substituted or unsubstituted amino or aminomethyl...
4081477 Pinane derivatives  
Pinanes substituted by a group X in the 3-position which group is formyl, or its alkyl-acetals or alkyl-hemiacetals, carboxylic acid, carboxylic acid chloride, carboxylic acid amide, hydroxymethyl...
4078066 Cyclohexane tetrols and derivatives thereof  
The compounds of the invention have the formula ##STR1## wherein Y is a radical of the formula ##STR2## or of the formula ##STR3## WHEREIN (CH2) is a straight or branched chain alkyl radical, n is...
4078085 3-Aminomethyl-4-homoisotwistane and its salt and process for producing same  
3-Aminomethyl-4-homoisotwistane acid addition salts produced by the steps of reducing 4-homoisotwistane-3-carboxylic acid amide or 4-homoisotwistyl-3-cyanide represented by the following general...
4061774 Halogenated amino methyl adamantane derivatives  
Novel 2-substituted-1-methylamino adamantanes of formula: ##STR1## where X is hydroxyl or halogeno, and R1, R2 and R3 are hydrogen or C1-4 alkyl or R2 and R3 together with the nitrogen form a...
4022788 Indane tetrol amines  
The compounds of the invention have the formula ##STR1## wherein Y is a radical of the formula ##STR2## or of the formula ##STR3## wherein (CH2) is a straight or branched chain alkyl radical, n is...
3996246 Resolution of racemic pantolactone  
A process for resolving racemic α-hydroxy-β,β-dimethyl-γ-butyrolactone, referred to as D,L-pantolactone, into its optical antipodes, based on the separation of diastereomeric salts of D,L-pantoic...
3984407 Diene intermediates for indantetrol derivatives  
Compounds are provided having the structure ##SPC1##Wherein n is 1, 2 or 3, m and m' are 0, 1 or 2, R1, R2, R3 and R4 may be the same or different and can be hydrogen, lower alkyl, halolower...
3947458 Preparation of amines  
Amines are prepared by reacting ammonia, a primary amine or a secondary amine with an olefin, carbon monoxide and water in the presence of a rhodium catalyst which is rhodium oxide or a rhodium...
3931315 Alicyclic amino compounds and their production  
An alicyclic amino compound of the general formula: ##SPC1##Wherein R1, R2, R3, R4 and R5 are each hydrogen or alkyl having 1 to 6 carbon atoms; X is each hydrogen, alkyl having 1 to 6 carbon...
3915983 Substituted benzimidazoles  
Benzimidazoles of the formula ##SPC1## Wherein R1 is alkyl, R2 is alkyl, cyclo-alkyl, benzyl or phenyl, SR2 being in 2- or 3-position, R3 is hydrogen, alkyl, aliphatic saturated alkanoyl,...
3912781 1-Hydroxymethyl-1,2,3,4-tetrahydrofluoranthene  
A new compound 1-hydroxymethyl-1,2,3,4-tetrahydrofluoranthene is prepared by reacting 1,2,3,4-tetrahydrofluoranthene with paraformaldehyde in a polar solvent, in the presence of a catalytic amount...
3894031 Indantetrol derivatives  
Compounds are provided having the structure ##SPC1## Wherein n is 1,2 or 3, m and m' are 0, 1 or 2, R1, R2, R3 and R4 may be the same or different and can be hydrogen, lower alkyl, halolower...
3852352 METHOD OF PRODUCING ALPHA-METHYL-1-ADAMANTYLMETHYL-AMINE HYDROCHLORIDE  
A method of producing α-methyl-1-adamantylmethylamine hydrochloride consists in that 1-adamantylmethylketone is reacted with ammonium formate, formamide, a mixture of formamide and formic acid or...
3845124 METHYLTRICYCLO(4.4.0.03.8)DECAN-1-METHYLAMINE  
1,269,832. Tricyclo-(4,4,0,03,8) decane derivatives. AYERST McKENNA & HARRISON Ltd. 10 July, 1969 [10 July, 1968; 27 Jan., 1969], No. 34899/69. Heading C2C. Novel compounds of Formula I where Q is...
3833653 2-AMINO-ADAMANTANE METHYLAMINE  
3789073 ADAMANTYLALKYLAMINOALKYL BENZAMIDES  
This invention relates to new adamantylalkyl-aminoalkyl benzamides of the general formula ##SPC1## And to acid addition salts and quaternary ammonium salts of such benzamides, substances which are...
3748359 ALKYLADAMANTANE DIAMINE  
3726872 AMINOMETHYLBICYCLONONENES AND DIHYDRO DERIVATIVES THEREOF  
3706801 1-AMINOADAMANTAN-4-OLS  
3697593 2-AMINOMETHYL-2-ADAMANTANOL  
2-Aminomethyl-2-adamantanol, useful as an intermediate in the preparation of antiviral 4-amino- and 4-amino-methyl-tricyclo[4.3.1.13,8 ]undecanes, can be prepared from 2-methylene adamantane by...
3657317 1 3-FUNCTIONALLY DISUBSTITUTED BICYCLOBUTANES  
3654301 ADAMANTANOPYRROLE COMPOUNDS  
3646066 ADAMANTYLAMINO-TETRAHYDRONAPHTHYL-OXYPROPANOLS AND ESTER DERIVATIVES  
3644356 ADAMANTANOPYRIMIDINE COMPOUNDS AND INTERMEDIATES THEREFOR  
1,265,971. Adamantane derivatives. LILLY INDUSTRIES Ltd. 21 May, 1969 [21 May, 1968], No. 24224/68. Heading C2C. Novel adamantane derivatives of the general formula wherein R and R1 are each a...
3627475 LEVELLING AGENTS FOR AND PROCESS FOR COLOURING A FIBROUS NATURAL POLYAMIDE WITH REACTIVE DYES  
1,218,715. Polyalkoxylated amines. SANDOZ Ltd. 14 May, 1969 [17 May, 1968; 27 May, 1968; 12 June, 1968, No. 24627/69. Heading C3R. [Also in Division DI] Alkoxylated amines of Formula I in which R...
3622628 AMINOPOLYCYCLODECANES  
1-Amino and aminomethylpentacyclo [6.2.0.02,7.04,10.05,9 ]-decanes, 3-amino and aminomethyltetracyclo [5.3.0.02,6.04,9 ]-decanes, and 1-amino and aminomethyltetracyclo [5.2.0.02,6.04,9 ]nonanes...

Matches 1 - 50 out of 89 1 2 >