Matches 1 - 50 out of 352 1 2 3 4 5 6 7 8 >

AcclaimIP-ad

Match Document Document Title
8778990 Betulinic acid derivatives and methods of use thereof  
This invention features betulinic acid derivatives having the formula: wherein the variables are defined herein. The invention also provides related compounds and intermediates thereof, as well as...
8455678 Process for the preparation of fesoterodine with low impurities content  
Disclosed is a process for the preparation of (R)-2-(3-diisopropylamino-1-phenylpropyl)-4-(hydroxymethyl)- phenol isobutyrate (Fesoterodine) or a pharmaceutically acceptable salt thereof having a...
8148045 Oxime ester compound and photopolymerization initiator containing the same  
A novel compound is a highly-sensitive photopolymerization initiator with excellent stability, low sublimability, excellent developability, and high transmittance in the visible region. It...
8049031 Solid forms of fesoterodine fumarate  
New solid forms of fesoterodine fumarate are described. In particular, amorphous fesoterodine fumarate, characterized by a powder X-ray diffraction spectrum as shown in FIG. 1 and by an IR...
7439384 Peroxyester preparation method  
The present invention relates to a process for the preparation of a peroxyester which can be used in particular in polymerizations, such as the polymerization of vinyl chloride, or in the...
7320998 Carbohydrate analog inhibitors of alpha-amylase  
The present invention provides carbohydrate analogs of the formula: wherein X is CH2, O, or NH, and R1-8 are independently H, a short hydrocarbon, a substituted amine, an alcohol, a substituted...
7273952 Substituted C-cyclohexylmethylamine derivatives  
Substituted C-cyclohexylmethylamine derivatives, methods for the production thereof, pharmaceuticals containing said compounds, the use of substituted C-cyclohexylmethylamine derivatives for...
RE39593 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects  
1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions.
7205290 Diphenylazetidinone with improved physiological properties, process for its preparation, medicaments comprising this compound, and its use  
The invention relates to the compound of the formula 1 and to its physiologically acceptable salts. The compound is suitable, for example, as a hypolipidemic.
RE39072 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same  
The present invention relates to a compound of the general formula wherein R1, R2, R3 and R4 are each a hydrogen or an acyl, a pharmaceutically acceptable acid addition salt thereof or a hydrate...
6767923 Benzhydryl derivatives  
Benzhydryl derivatives of the formula I, where the index and the variables are as defined below:X is oxygen or sulfur;R1, R3 are halogen, cyano, nitro, hydroxyl, mercapto, amino, alkyl, alkenyl,...
6693137 Sulphonamide derivatives  
The present invention relates to the potentiation of glutamate receptor function using certain sulphonamide derivatives. It also relates to novel sulphonamide derivatives, to processes for their...
6632959 Basic catalysts and process for producing carbonyl compound derivatives  
A base catalyst, obtained by formulating at least one alkali metal compound selected from the group consisting of alkoxides, hydroxides and oxides of alkali metals and an alkaline-earth metal...
6586409 Adjuvant compositions and methods for enhancing immune responses to polynucleotide-based vaccines  
The invention provides adjuvants, immunogenic compositions, and methods useful for polynucleotide-based vaccination and immune response. In particular, the invention provides an adjuvant of...
6503945 Cationic amphiphiles containing N-hydroxyalkyl group for intracellular delivery of biologically active molecules  
The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating...
6472555 Process for the production of esters from alcohols using acetic acid as acetylating and clays as catalysts  
The present invention relates to a process for the preparation of esters from alcohols using acetic acid as acetylating agent and clays as catalysts, which comprises the preparation of esters in a...
6472542 Method for alkylating the alpha carbon of the 2-methylbutyrate secondary chain of lovastatin  
Simvastatin is produced from lovastatin in high yield and in pharmaceutical purity by forming an amide of lovastatin and protecting the free hydroxyl groups of the lovastatin amide with...
6383499 Topical medicament for the treatment of psoriasis  
A topical medicament for the treatment of psoriasis comprises metallic iodine, virgin wax, a variety of oils of animal and plant origin, camphor, chlorophyll and benzoic acid in a pharmaceutically...
6348615 Process for producing (2R, 3S)-3-amino-1, 2-oxirane  
A process for producing (2R, 3S)-3-amino-4-phenylbutane-1,2-epoxide compounds which comprises treating a (2S, 3S)-3-amino-1-halo-2-hydroxy-4-phenylbutane compound or a (2S,...
6346516 Cationic amphiphiles containing N-hydroxyalkyl group for intracellular delivery of biologically active molecules  
The present invention provides novel cationic amphiphiles containing novel N-hydroxyalkyl group and therapeutic formulations containing the said amphiphiles that are capable of facilitating...
6344558 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effect  
1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical compositions.
6271398 Process for producing simvastatin and/or its derivatives  
A process for the production of simvastatin and its analogues that is efficient, economical and convenient involves the use of hydroxyl protected intermediates of formula (III) or (VII). These...
6248737 1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects  
1-phenyl-3 -dimethylaminopropane compounds corresponding to the formula I ##STR1##a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical...
6225334 Glyoxylic acid derivatives  
The invention concerns novel glyoxylic acid derivatives, a process for their preparation and their use as pesticides.
6222076 Process for the preparation of substituted cycloketones  
The invention relates to a novel process for the preparation of hydroxyalkyl- and acyloxyalkyl-substituted cycloketones by free-radical addition of hydroxyalkenes and acyloxyalkenes respectively...
6214873 2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same  
The present invention relates to a compound of the general formula ##STR1##wherein R1, R2, R3 and R4 are each a hydrogen or an acyl, a pharmaceutically acceptable acid addition salt thereof or a...
6159988 Arylcycloalkyl derivatives, their production and their use  
Compounds of formula I, ##STR1## and the physiologically tolerable salts thereof, wherein the substituents R1 -R4 have the meanings given in the specifications and show an activity against...
6124270 Use of a cationic amphipathic compound as a transfection agent, vaccine additive or drug  
A cationic amphipathic compound of formula (I), ##STR1## wherein A is a single bond, an NH--R' grouping or (a), wherein --R'-- is a straight or branched, optionally substituted, saturated or...
6124360 Solid compositions suitable for oral administration comprising non hygroscopic salts of L-carnitine and alkanoyl-L-carnitine with 2-aminoethanesulfonic acid  
Stable and non hygroscopic salts of L-carnitine or lower alkanoyl-L-carnitine with 2-aminoethanesulfonic acid are disclosed suitable for preparing solid compositions useful as dietary/nutritional...
5985239 Derivatives of N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters  
The present invention relates to N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters, and their use as agents for water disinfection and as mild oxidizing agents for the...
5910578 Phenylazoanilines  
Azo dyes of the formula ##STR1## where X is oxygen or a radical of the formula NR6, where R6 is hydrogen or substituted or unsubstituted C1 -C13 -alkyl, R1 is substituted or unsubstituted C1 -C13...
5907054 Process for the polymerization of cyclic ether  
The present invention provides a process for the production of an ester of polyoxyalkylene glycol on an industrially favorable basis which comprises the ring opening polymerization of a cyclic...
5886138 Process for the preparation of tetrahydrofuran polymers  
A process for the continuous and discontinuous production of tetrahydrofuran polymers by homopolymerizing tetrahydrofuran or copolymerizing tetrahydrofuran with 1,2-alkylene oxides in the presence...
5854224 Composition and method for delivery of nucleic acids  
The present invention provides a method for introducing nucleic acids into cells. The method involves exposing the cells to a compound having the formula ##STR1## in which: w is a nucleic acid x...
5773654 7-(5-substituted cyclopentyl) and (5-substituted cyclopentenyl) heptyl alcohols, heptylamines and heptanoic acid amides, and method of lowering intraocular pressure in the eye of a mammal by administration of these compounds  
Compounds of the formula ##STR1## where the dotted line represents a bond or the absence of a bond, the wavy lines represent bonds which are either in cis or trans configuration; R1 represents H,...
5763646 Process for manufacturing simvastatin from lovastatin or mevinolinic acid  
A process for preparing simvastatin from lovastatin or mevinolinic acid in salt form comprises treating either starting material with cyclopropyl or butyl amine, the pyranone ring thereby being...
5763653 Key intermediates in the manufacture of simvastatin  
A process for preparing simvastatin from lovastatin or mevinolinic acid in salt form comprises treating either starting material with cyclopropyl or butyl amine, the pyranone ring thereby being...
5753701 N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters as novel safe agents for water disinfection  
The present invention relates to N-chloro-N-methyl glucamine and N-chloro-N-methyl glucamine esters, and their use as agents for water disinfection and as mild oxidizing agents for the...
5686642 Compounds useful for the preparation of bi-and polyfunctional reactive dyestuffs  
Reactive dyestuffs which, in the form of the free acid, correspond to the following formula ##STR1## wherein D is the radical of an organic dyestuff of the mono-azo, polyazo or metal complex azo...
5672735 Process for the preparation of a dicarboxylic acid di-chloride  
The present invention refers to a Process for the preparation of S-(-)-5- 2-(acetyloxy)-1-oxopropyl!amino!-2,4,6-triiodo-1,3-benzenedi carb oxylic acid dichloride of formula (I) comprising the...
5616746 Use in cosmetics of lipophilic derivatives of amino deoxyalditols, cosmetic compositions containing them, and novel alkyl carbamates  
The invention is characterized by the use in cosmetic compositions of one or more lipophilic derivatives of amino deoxyalditols corresponding to the general formula: ##STR1## in which: R1 is a...
5604256 Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition  
Compounds of formula (I): ##STR1## (in which: R is hydrogen, methyl or hydroxy; X is alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or a heterocyclic group; A is a single bond, or an alkylene,...
5466872 Poly (oxyalkylene) aromatic ethers  
Fuel compositions containing a major amount of hydrocarbons boiling in the gasoline or diesel range and an effective deposit-controlling amount of a poly(oxyalkylene) aromatic ether having the...
RE34805 Benzonaphthalene derivatives and their use in therapeutic and cosmetic compositions  
A benzonaphthalene compound has the formula ##STR1## wherein R1 represents ##STR2## or (ii) --CH2 OH; R6 represents ##STR3## or OR7 wherein R7 represents hydrogen, alkyl having 1-20 carbon atoms,...
5362905 Process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride  
An improvement to a process for the preparation of L-5-(2-acetoxy-propionylamino)-2,4,6-triiodo-isophthalic acid dichloride by reacting 5-amino-2,4,6-triiodo-isophthalic acid dichloride with...
5326786 5,6,7,9-tetrahydro-1,2,3-trimethoxy-9-oxobenzo[alpha]heptalene derivative and pharmaceutical use  
Compounds represented by the formula ##STR1## wherein R1 and R2 each represent a hydrogen atom or a protective group for a hydroxyl group, or R1 and R2 combine to represent a protective group for...
5264618 Cationic lipids for intracellular delivery of biologically active molecules  
Disclosed are cationic lipids capable of facilitating transport of biologically active agents into cells, including the transfection of cells by therapeutic polynucleotides, the delivery of...
5241107 Carbocyclic derivatives  
The present invention relates to compounds of formula (I) ArCH2 R1 (I)or a monomethyl or monoethyl ether thereof (the compound of formula (I) including these ethers may contain no more than 30...
5240630 Refrigeration compositions containing diester-amides of dialkanolamines  
A refrigeration lubricant suitable for use with R-134a-type refrigerants comprises at least one dialkanolamine diester-amide oil corresponding to one of the formulas: ##STR1## in which formulas R...
5198559 N-acyl and O-acyl derivatives of N,N-bis(2,2-dimethyl-3-hydroxypropyl)amine, their preparation and use  
The present invention relates to N acyl and O acyl derivatives of N,N-bis(2,2-dimethyl-3-hydroxypropyl)amine which are produced as follows: ammonium halide, sulphate or aldehyde, and isobutyl...
Matches 1 - 50 out of 352 1 2 3 4 5 6 7 8 >