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9040538 Pyrimidines as novel therapeutic agents  
The present invention features compounds having the Formula (Ia) and (Ib) (e.g., a compound of any of Formulas ((Ia-2)-(Ia-21)), including other tautomers, stereoisomers, E/Z stereoisomers,...
9023874 Fluorinated oxa or thia heteroarylalkylsulfide derivatives for combating invertebrate pests  
The invention relates to alkylsulfide derivatives compounds of formula I as hereunder depicted or the enantiomers or veterinarily acceptable salts thereof which are useful for combating or...
8962851 One-pot process for the preparation of benzimidazole derivatives  
The present invention discloses one pot process for enantioselective synthesis of single enantiomers of substituted sulphoxides 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles or said compounds...
8889878 Haloalky-substituted amides as insecticides and acaricides  
The present invention relates to halogen-substituted amide derivatives of the general formula (I) in which R1 to R6, Q1 to Q8, A, V, W, X, Y, n and m are each defined as described in the...
8883037 Chiral compounds, cholesteric and ferroelectric liquid crystal compositions comprising these chiral compounds, and liquid crystal displays comprising these liquid crystal compositions  
Chiral liquid crystal compounds of the general formula (1): in which at least one of R1 and R2 is a chiral substituent,K may be a single bond or the same as K1-5 and K1-5 denote a six-membered...
8840866 Styrylpyridine derivatives and their use for binding and imaging amyloid plaques  
This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This...
8791161 Sulfur derivatives as chemokine receptor modulators  
The present invention relates to novel sulfur derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of chemokine...
8785480 Functionalized pyridine N-oxides and processes for the preparation of the same  
In one embodiment, processes for the preparation of certain functionalized pyridine N-oxides are provided. In one form, the functionalized pyridine N-oxides include...
8742125 Process for the preparation of 2-trifluoromethyl-5-(1-substituted)alkylpyridines  
2-Trifluoromethyl-5-(1-substituted)alkylpyridines of formula (I) whereinR1 and R2 independently represent H, C1-C4 alkyl, or either of R1 or R2 taken together with R3 represent a 4- to 6-membered...
8674110 Pyridylacetylenes for use as radiotracers and imaging agents  
The present invention relates to novel pyridylacetylene derivatives of formula I their preparation, their use as radio-traces/markers and compositions containing them.
8629280 Methods for oligomerizing olefins with chromium pyridine ether catalysts  
The present invention provides a method of producing oligomers of olefins, comprising reacting olefins with a catalyst under oligomerization conditions. The catalyst can be the product of the...
8623942 Epoxy resin composition, curing agent, and curing accelerator  
The present invention provides a liquid curable epoxy resin composition that has excellent storage stability and curing properties and provides a cured product having excellent properties,...
8580821 Serotonin transporter (SERT) inhibitors for the treatment of depression and anxiety  
The present invention relates to trans-derivatives of formula wherein R1, R2, R3, and the dotted line are as defined herein and to pharmaceutically acceptable acid addition salts thereof. The...
8580142 Liquid crystal compound, liquid crystal composition and liquid crystal display device  
The invention provides a liquid crystal compound having stability to heat, light and so forth, a wide temperature range of a nematic phase, a small viscosity, a suitable optical anisotropy, a...
8530388 Cyclopentadione derived herbicides  
Compounds of formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.
8530665 Crystalline (R)-(E)-2-(4-(2-(5-(1-(3,5-dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyrazol-1-yl)ethanol  
The present invention provides crystalline (R)-(E)-2-(4-(2-(5-(1-(3,5 -dichloropyridin-4-yl)ethoxy)-1H-indazol-3-yl)vinyl)-1H-pyra zol-1-yl)ethanol useful in the treatment of cancer.
8519144 Process for the preparation of aryl-piridyl compounds  
A method is described for the preparation of aryl-pyridine compounds of formula (I) by cross-coupling reaction, promoted by catalytic systems based on palladium or nickel between compounds of...
8507688 Process for preparing aryl- and heteroarylacetic acid derivatives  
The present invention relates to a process for preparing α-arylmethylcarbonyl compound of the formula (III), characterized in that aryl- and heteroarylacetic acids and derivatives thereof of the...
8455656 Kinase inhibitors  
The present invention relates to drug delivery systems comprising ocular implant, which include organic molecules, capable of modulating tyrosine kinase signal transduction in order to regulate,...
8440834 1-phenyl-2-pyridinyl alkyl alcohol compounds as phosphodiesterase inhibitors  
1-Phenyl-2-pyridinyl alkyl alcohol compounds are effective as inhibitors of the phosphodiesterase 4 (PDE4) enzyme and may be used to prevent and/or treat certain diseases or conditions.
8372975 Liquid crystal compound having difluoropropenyleneoxy bonding group  
The invention provides a liquid crystal compound having general physical properties necessary for the compound, namely stability to heat, light and so forth, a wide temperature range of a liquid...
8367838 Amines or amino alcohols as GLYT1 inhibitors  
The invention relates to the use of compounds of formula I wherein the substituents are described in the description and claims for the treatment of psychoses, dysfunction in memory and learning,...
8344152 Process for producing pyridylethylthio compound, modified ion exchanger and process for producing the same, and process for producing bisphenol compound  
The present invention relates to a process for producing a pyridylethylthio compound which is improved in yield of the pyridylethylthio compound. In a process for producing a pyridylethylthio...
8338553 Solvatochromic molecularly imprinted polymer for chemosensing  
Disclosed are a solvatochromic functional monomer having the chemical structure and a process for preparing the same. The solvatochromic functional monomer can be used for fabrication of...
8338602 Quaternary nitrogen heterocyclic compounds for detecting aqueous monosaccharides in physiological fluids  
Quaternary nitrogen heterocyclic boronic acid-containing compounds are described, which are sensitive to glucose and fructose, as well as a variety of other physiologically important analytes,...
8263628 Fluorine-containing organosulfur compound and pesticidal composition thereof  
There is provided a fluorine-containing organosulfur compound having an excellent control effect on harmful arthropods, which is represented by the formula (I): wherein m represents 0 or 1; n...
8158021 Polymerizable liquid crystal compound, polymerizable liquid crystal composition, liquid crystalline polymer, and optical anisotropic article  
A polymerizable liquid crystal compound shown by the following formula (I), a polymerizable liquid crystal composition that includes the polymerizable liquid crystal compound and a chiral compound...
8158656 2-indolinone derivatives as multi-target protein kinase inhibitors and histone deacetylase inhibitors  
The present invention relates to 2-indolinone derivatives which are capable of inhibiting protein kinases and histone deacetylases. The compounds of this invention are therefore useful in treating...
8129539 Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines  
2-Substituted-5-(1-alkylthio)alkylpyridines are produced efficiently and in high yield from a non-pyridine source by cyclization.
8067609 Methods for oligomerizing olefins with chromium pyridine thioether catalysts  
The present invention provides a method of producing oligomers of olefins, comprising reacting olefins with a chromium based catalyst under oligomerization conditions. The catalyst can be the...
8067600 Histone deacetylase inhibitors and methods of use thereof  
One aspect of the invention relates to HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided. The invention also provides methods for...
8067602 Asymmetric cyanine fluorescent dyes, compositions and their use in staining biological samples  
Asymmetric cyanine fluorescent dyes are represented by general formula I. These kinds of dyes may be used as a staining agent for nucleic acids, with the spectra at 600-900 nm in the near-infrared...
8012547 Pyridine compounds for liquid-crystalline mixtures  
The invention relates to liquid-crystalline compounds of the formula I in which R1, R2, A1, A2, A3, A4, Z1, Z2, Z3, V, a, b and c have the meanings indicated in claim 1, and to liquid-crystalline...
7943643 Aryl substituted pyridines and the use thereof  
This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1-R4 are set in the specification. The invention...
7939542 Cinnamaldehyde derivatives having improved solubility in water, a method for preparing the same and a pharmaceutical composition comprising the same  
Disclosed herein are a novel cinnamaldehyde compound represented by Chemical Formula 1 or pharmaceutically acceptable salts thereof. The cinnamaldehyde compound has improved solubility in water...
7932271 Heterocyclic methyl sulfone derivative  
Provided is a compound capable of inhibiting production or secretion of β amyloid protein. A compound represented by the following formula (1): (wherein, R1 represents a heterocyclic group which...
7906675 Compounds for the treatment of metabolic disorders  
A biologically active agent, wherein the agent is a compound of the formula: Wherein A, R5, R9, X, Q and n, m, q are defined herein below.
7897779 Ionic UV-A sunscreens and compositions containing them  
The present invention relates to novel 1,4-dihydropyridine derivatives, to novel cosmetic or dermatological sunscreen compositions containing these derivatives and the use of these derivatives for...
7888365 Tri-aryl/heteroaromatic cannabinoids and use thereof  
Cannabinoid derivatives according to formula (I) are disclosed wherein, X, Y, R1, R2, and W can have the definitions provided herein. Without limitation, use of such compounds, their salts or...
7888377 Monocyclic and bicyclic himbacine derivatives useful as thrombin receptor antagonists  
Monocyclic and bicyclic himbacine derivatives of the formula or a pharmaceutically acceptable salt or solvate of said compound wherein represents an optional double bond and wherein Gn, Jn, R3,...
7872022 Serotonin transporter (SERT) inhibitors for the treatment of depression and anxiety  
The present invention relates to trans-derivatives of formula wherein R1, R2, R3, and the dotted line are as defined herein and to pharmaceutically acceptable acid addition salts thereof. The...
7829613 Azinium salts as splayant for layered materials  
The present invention relates to a splayant, that is, an intercalant/exfoliant, comprising an azinium compound capable of splaying a layered material.
7745439 Indene derivatives and process for the preparation thereof  
The inventive indene derivatives of formula (I) are capable of selectively modulating the activities of peroxisome proliferator activated receptors (PPARs), causing no adverse side effects, and...
7709650 Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines  
2-Substituted-5-(1-alkylthio)alkylpyridines are produced efficiently and in high yield from a non-pyridine source by cyclization.
7705021 Isoindolone compounds, compositions containing the same, and methods of use thereof for the treatment of viral infections related to the etiology of cancer  
Isoindolone derivatives, compositions containing the same, and methods of use thereof for the treatment or prophylaxis of viral infection are disclosed.
7666883 Antimalarial Baylis-Hillman adducts and a process for the preparation thereof  
The present invention is directed towards the synthesis of novel and new chloropyridine skeleton based compounds and these are Bayllis Hillman adducts having a remarkable in vitro anti-malarial...
7642272 Cannabinoid receptor ligands  
There are disclosed compounds of the formula I a pharmaceutically acceptable salt or solvate of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are...
7632879 Azinium salts as splayant for layered materials  
The present invention relates to a splayant, that is, an intercalant/exfoliant, comprising an azinium compound capable of splaying a layered material.
7629379 Substituted phosphonate fluorescent sensors and use thereof  
The invention relates to new compounds of formula (1) wherein R is hydrogen or a linear or branched C1-40alkyl; where X is O, S, or NR1 where R1 is a hydrogen, a linear or branched C1-40 alkyl,...
RE41008 Method for producing 5-aryl nicotinaldehydes  
The invention relates to a process for the preparation of 5-arylnicotinaldehydes by reduction of the corresponding 5-arylnicotinic acids by catalytic hydrogenation in the presence of carboxylic...