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8981058 Gelatin sponge comprising an active ingredient, its preparation and use  
The present invention is directed to a method for manufacturing a cross-linked gelatin sponge having a surface by providing a cross-linked gelatin sponge, wetting the surface of the sponge by...
8962131 Transparent conductive film comprising water soluble binders  
Transparent conductive films comprising silver nanowires dispersed in polyvinyl alcohol or gelatin can be prepared by coating from aqueous solvent using common aqueous solvent coating techniques....
8906679 Composite for thermo-sensitive cell-tissue transplanted scaffold and use thereof  
A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can...
8901017 Formaldehyde-free proteinaceous binder compositions  
Binder compositions are described, where the compositions include a protein, a first crosslinking compound that includes a carbohydrate, and a second crosslinking compound that includes two or...
8859735 Gelatin alkyd peptides and uses thereof  
Polypeptides are provided, where the polypeptides include one or more groups of formula —R1—C(O)R2, where R1 is an amino acid side chain, R2 is a C8-C24 polyunsaturated alkenyl group, and the...
8785598 Coenzyme Q10 nanoparticles, preparation method thereof and composition containing said nanoparticles  
Provided are a coenzyme Q10 nanoparticle, a method of preparing the same and a composition having the nanoparticle. According to the present invention, Coenzyme Q10 may be dissolved in only a...
8779097 Accelerated gelation of regenerated fibroin  
The invention discloses a process for the acceleration of gelling time of regenerated silk fibroin using gelling agent, preferably silica to create a porous structure, devoid of microbial growth.
8703117 Cross-linked compositions  
Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and...
8632785 Clostridial toxin pharmaceutical composition containing a gelatin fragment  
A botulinum toxin pharmaceutical formulation comprising a botulinum toxin and a low molecular weight recombinant or native gelatin fragment suitable for administration to a human patient, and...
8507659 Method for chemically modifying biopolymer and polypeptide  
It is an object of the present invention to provide a method for chemically modifying biopolymer and polypeptide with a hydrophobic compound or a compound which causes degradation or reaction...
8501196 Pharmaceutical compositions containing botulinum neurotoxin  
This invention relates to the use of a composition comprising a polysaccharide and a botulinum toxin for reducing a skin wrinkle. In some embodiments, the polysaccharide comprises disaccharides....
8475812 Gelatin sponge comprising an active ingredient, its preparation and use  
The present invention is directed to a method for manufacturing a cross-linked gelatin sponge having a surface by providing a cross-linked gelatin sponge, wetting the surface of the sponge by...
8470597 Composite for thermo-sensitive cell-tissue transplanted scaffold and use thereof  
A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can...
8435953 Sustained release composition containing SDF-1  
An object of the present invention is to provide a sustained release composition containing SDF-1. The present invention provides a sustained release composition containing (1) SDF-1 and (2) a...
8367388 Cross-linked compositions  
Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and...
8318903 Benign solvents for forming protein structures  
A benign solvent for dissolving proteins comprises alcohol, salt and water. The ratio by volume of water to alcohol is between about ninety-nine-to-one and about one-to-ninety-nine. A salt...
8293873 Combination of amino acid solution and a gelatin derivative for inhibiting renal up-take  
The invention relates to a combination of a solution of a gelatin derivative and at least one amino acid, if desired in the form of a pharmaceutically acceptable salt or carboxylic acid...
8268968 Method for producing modified biopolymer and method for crosslinking biopolymer  
It is an object of the present invention to provide a method wherein a structure which was prepared with a biopolymer such as gelatin is chemically modified with the use of a low-volatile chemical...
8252747 Tissue adhesive sealant  
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive...
8221783 Medical devices with triggerable bioadhesive material  
Described herein are implantable medical devices comprising a biocompatible polymer comprising a triggerable bioadhesive property that allows the device to adhere to body tissue. The triggerable...
8158755 Production method of gelatin particles  
A method of producing gelatin particles, including immersing a discharge spout in a hydrophobic solvent, discharging an aqueous gelatin solution from a nozzle tip into the hydrophobic solvent, and...
8158754 Multiple modified derivatives of gelatin and crosslinked material thereof  
Disclosed is a kind of multiple modified derivatives of gelatin having not only the structure of formula (I) but also one of structures of formula (II), (III), and (IV) as well, wherein, G refers...
8124757 Thiol-modified macromolecule derivatives and cross-linked materials thereof  
The disclosed is thiol-modified macromolecule derivatives having the general formula of (I) or (II), as well as the disulfide bond cross-linked materials and the thiol-reactive crosslinker...
8048446 Electrospun blends of natural and synthetic polymer fibers as tissue engineering scaffolds  
Non-woven fibrous scaffolds made by electrospinning from the synthetic biodegradable polymer such as, for example, poly(lactic-co-glycolic acid) (PLGA) and natural proteins, such as, for example,...
7928069 Crosslinked compounds and methods of making and using thereof  
Described herein are crosslinked compounds useful in numerous treatments. Described herein are methods of making crosslinked compounds via (1) die oxidative coupling of two or more thiol compounds...
7923031 Haemostatic sprays and compositions  
The present invention is directed to a powder delivery system containing a composition comprising gelatin or collagen powder having a mean particle size of at least 10 μm. The gelatin or collagen...
7897728 Process for making a low molecular weight gelatine hydrolysate  
The present invention provides a process to make a gelatine hydrolysate, a gelatine hydrolysate, and gelatine compositions including gelatine hydrolysates. More specifically, the invention...
7855273 Method for manufacturing gelatin with reduced endotoxin content and low endotoxin gelatin  
A method of manufacturing gelatin with reduced endotoxin content. The method comprises processing a starting material gelatin-containing solution containing gelatin and an endotoxin with an...
7758895 Methods for purifying insoluble bone gelatin  
The present invention provides methods for purifying insoluble bone gelatin and uses for insoluble bone gelatin. The process for isolating insoluble bone gelatin from bone tissue includes grinding...
7700660 Method of treating chronic ulcers  
The invention provides a method of treating a chronic ulcer, such as a diabetic ulcer, comprising administering a therapeutic amount of a hydrogel matrix to the ulcer, the matrix composition...
7659372 Menstrual fluid simulant containing blood product, gelatin, polyacrylamide and buffer  
Menstrual fluid simulants may consistently emulate the physical characteristics of real menstrual fluid, including but not limited to, viscosity, stringiness, surface tension and size and...
7605231 Gelatin derivatives and high-molecular micelle comprising the derivatives  
The present invention relates to a gelatin derivative having an organic compound as a graft chain and a high-molecular weight micelle containing the gelatin derivative. As the organic compound, a...
7553613 Use of defibrinated blood for manufacture of hemoglobin-based oxygen carrier  
Red blood cells are purified by defibrinating whole blood and then filtering the defibrinated whole blood, whereby at least a portion of a plasma component is separated from the red blood cells to...
7485323 Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions  
The present invention provides a process to make a gelatine hydrolysate, a gelatine hydrolysate and gelatine compositions comprising gelatine hydrolysates. More specifically, the invention...
7393928 Recombinant gelatins  
The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
7320962 Hemoactive compositions and methods for their manufacture and use  
Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a...
7238657 Cartilage/Bone inducing materials for preparation  
A cartilage and bone morphogenetic repairing composition which contains a bone morphogenetic protein and a polyoxyethylene-polyoxypropylene glycol is disclosed. It is preferable that the molecular...
7138373 Polysaccharide-based polymers and methods of making the same  
Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine...
7129210 Tissue adhesive sealant  
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive...
7098315 Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge  
A method of preparing a collagen sponge comprises mixing air into a collagen gel, so as to obtain a collagen foam which is dried. From the dried product thereby obtained, collagen sponge is...
7094580 Methods for producing pure perlecan and other heparan sulfate proteoglycans  
A method of perlecan isolation (from the EHS tumor) which produces “clean” (i.e. substantially “pure”) perlecan is disclosed. Clean perlecan is thus produced in sufficient quantities for use in a...
7008624 Antagonists of interleukin-15  
Antagonists of mammalian interleukin-15 (“IL-15”) are disclosed and include muteins of IL-15 and modified IL-15 molecules that are each capable of binding to the IL-15Rα-subunit and that are...
6995242 Process for producing insoluble and soluble collagen protein products from poultry skins and use thereof  
A method of extracting and fractionating collagen-rich proteinaceous materials and derivatives from poultry skin tissue and the development of the proteinaceous materials to collagen-based protein...
6992172 Recombinant gelatins  
The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
6986984 Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier  
Red blood cells are purified by defibrinating whole blood and then filtering the defibrinated whole blood, whereby at least a portion of a plasma component is separated from the red blood cells to...
6987001 Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents  
The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL,...
6911071 Photographic element containing acid processed gelatin  
The present invention relates to an imaging member comprising poultry gelatin. In one embodiment, the poultry gelatin is located preferably in at least one layer in the upper half of said imaging...
6903071 Cartilage/bone inducing materials for reparation  
A cartrilage and bone morphogenetic repairing composition comprising a collagen-free aqueous solution of a polyoxyethylene-polyoxypropylene and an effective amount of a bone morphogenetic protein,...
6831058 Crosslinked gelatin gel preparation containing basic fibroblast growth factor  
The present invention relates to a crosslinked gelatin gel preparation containing a basic fibroblast growth factor hereinafter referred to as bFGF wherein a crosslinked gelatin gel is used as a...
6709864 Adipogenic differentiation of human mesenchymal stem cells  
A composition which comprises human mesenchymal stem cells which have the potential to differentiate into cells of more than one connective tissue type and a composition which induces cells from...