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9040060 Hydrolytically degradable alkylene oxide based polymers  
The present invention provides a water soluble, non-peptidic polymer comprising two or more alkylene oxide-based oligomers linked together by hydrolytically degradable linkages such as carbonates....
9034930 Biodegradable polymeric hydrogel composition  
A biodegradable polymeric hydrogel composition including a component A and component B forming a β-aminoester linkage such that the linkage results in gelation, wherein component A is water...
9034390 Anti-microbial composition and method for making and using same  
The present invention generally relates to anti-microbial formulations and methods of their use and production. The formulations of the present invention are effective as broad spectrum...
9023897 Biodegradable drug delivery compositions  
A biodegradable drug delivery compositions comprising a triblock copolymer containing a polyester and a polyethylene glycol and a diblock copolymer containing a polyester and an end-capped...
9017644 Methods of treating autoimmune disorders and/or inflammatory disorders  
The present invention relates to dendrimer compositions configured for treating inflammatory disorders and autoimmune disorders, and related methods of synthesis. Specifically, the present...
9000052 Perfuming compositions and uses thereof  
A perfuming composition capable of prolonging the release of a perfuming component into the surrounding environment when applied on a surface. This composition utilizes hydrophobic block...
8986728 Soluble implantable device comprising polyelectrolyte with hydrophobic counterions  
The present invention provides an implantable device having a biosoluble coating or a biosoluble body structure comprising a polyelectrolyte and a counterion and the methods of making and using...
8980957 Methods for the preparation of biocompatible polymers, the polymers and their uses  
The subject invention relates to a method of preparing a biocompatible polymer comprising epsilon-linked L-lysine having free alpha-amino and carboxy functions. The invention further encompasses...
8980238 Mucoadhesive polymers having vitamin B partial structures  
Because of the formation of disulfide bridges with mucus glycoproteins, the mucoadhesive properties of polymeric compounds can be significantly improved by the covalent attachment of thiol...
8962008 Hybrid polymeric materials for medical applications and preparation thereof  
The present invention relates to a novel polymeric material with enhanced hydrophilicity for medical use comprising a biocompatible polyester material selected from the group consisting of...
8927529 Treatment of back pain by injection of microparticles of dexamethasone acetate and a polymer  
A method for the treatment of back pain by injection of an injectable flowable composition in the epidural space, wherein the composition is composed of microparticles of dexamethasone acetate and...
8916616 Multi-functional polymeric materials and their uses  
Multifunctional polymers are disclosed having a smart segment and a biodegradable segment. Advantageously, the biodegradable segment includes a hydrophilic segment and a hydrophobic segment....
8916615 PH-sensitive polymer hydrogel with dual ionic transition and use thereof  
Disclosed is a dual-transition polymeric hydrogel. Also, provided is the use of the dual-transition polymeric hydrogel as a carrier for drug delivery and disease diagnosis, or in the preparation...
8900610 Biocidal fibrous and film materials comprising silver and chlorite ions  
Disclosed are compositions comprising a hydrophilic polymer, a hydrophobic polymer, a silver ion, and a chlorite anion, wherein the silver ion associates with at least one hydrophilic or...
8877172 Zwitterionic polymer bioconjugates and related methods  
Zwitterionic polymer and mixed charge copolymer bioconjugates, methods for making and using the bioconjugates.
8871859 Crosslinked pigment dispersion based on structured vinyl polymeric dispersants  
The present disclosure provides an aqueous dispersion comprising a solid particle and a structured vinyl polymeric dispersant, wherein said structured vinyl polymer dispersant comprises at least...
8865143 Reversely thermo-reversible hydrogel compositions  
A reversely thermo-reversible hydrogel composition comprising a water soluble block copolymer comprising at least two blocks of polyethylene oxide and at least one block of polypropylene oxide,...
8858972 Antimicrobial medicotechnical product, process for its preparation and use  
The invention relates to a medicotechnical product having an antimicrobial finish of a complex material of metal nanoparticles and macromolecules, the macromolecules being formed at least...
8852626 Controlled-release CNS modulating compositions and methods for the treatment of otic disorders  
Disclosed herein are compositions and methods for the treatment of otic disorders with CNS modulating agent compositions and compositions administered locally to an individual afflicted with an...
8846077 High throughput fabrication of nanoparticles  
This application provides a high throughput method of making nanoparticles that utilizes plates comprising wells (e.g., 96-well plates).
8840951 Method for preparation of a controlled release system  
The present invention relates to a method for the preparation of a controlled release system and especially to a method for entrapment of compounds in polymer carriers for controlled release of...
8835513 Drug delivery devices  
Compositions provided by contacting a biotin-containing component and an avidin-containing component are useful as drug delivery devices. Bioactive agents may be covalently bound to the...
8822546 Flowable pharmaceutical depot  
Flowable pharmaceutical depots are described. The flowable pharmaceutical depot includes a polyester, such as a polylactic acid or a poly(trimethylene carbonate) endcapped with a primary alcohol...
8802738 Polyesters with grafted zwitterions  
The invention relates to polymers, such as aliphatic polyesters, with grafted zwitterions. More particularly, the invention relates to polyester-graft-phosphorylcholine polymers prepared by...
8784870 Controlled release compositions for modulating free-radical induced damage and methods of use thereof  
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an...
8785569 Drug carrier with chelating complex micelles and the application thereof  
This invention provides Chelating Complex Micelles as a drug carrier. The Chelating Complex Micelles can load drugs without changing their structure, and therefore extend the half-life of drugs in...
8779008 Polymeric micelles for drug delivery  
The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
8771739 Pharmaceutical compositions for poorly soluble drugs  
The present invention provides a pharmaceutical composition of a practically insoluble drug, wherein the composition may be administered with food or without food. The composition may be in the...
8753619 Tissue adhesives and sealants and methods for their use  
Compositions provided by mixing a biotin-containing component and an avidin-containing component are useful as an adhesive or sealant for medical/surgical uses.
8673985 Polycarbonate-polyorganosiloxane- and/or polyurethane-polyorganosiloxane compounds  
The present invention relates to novel polycarbonate-polyorganosiloxane and/or polyurethane-polyorganosiloxane compounds, methods for their production, their use, functional formulations...
8673986 Coacervate having an ionic polymer mixed with the adhesive protein of a mussel or of a species of the variome thereof  
The present invention relates to a coacervate comprising a mussel adhesive protein and an anionic polymer, and more particularly, to a coacervate prepared by mixing a mussel adhesive protein with...
8663700 Drug loaded polymeric nanoparticles and methods of making and using same  
The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of...
8652528 Drug loaded polymeric nanoparticles and methods of making and using same  
The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of...
8653030 Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release  
A formulation containing a biologically active compound having a chemical structure with hydrogen bonding sites, a first biocompatible, hydrolytically degrading polycarbonate with hydrogen bonding...
8642666 Biodegradable block copolymeric compositions for drug delivery  
An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling...
8636993 Water-in-oil emulsions with anionic groups, compositions, and methods  
Water-in-oil emulsions, compositions, and methods that include a vinyl polymer having a pKa of less than 4 that includes anionic group-containing side chains and alkyl-Y-containing side chains,...
8629186 Polymer micelles containing anthracyclines for the treatment of cancer  
The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using...
8617592 Self-assembled particles from zwitterionic polymers and related methods  
Zwitterionic block copolymers and zwitterionic conjugates that advantageously self-assemble into particles, particles assembled from the zwitterionic block copolymers and zwitterionic conjugates,...
8609142 Drug loaded polymeric nanoparticles and methods of making and using same  
The present disclosure generally relates to methods of making nanoparticles having about 0.2 to about 35 weight percent of a therapeutic agent; and about 10 to about 99 weight percent of...
8586637 Stable and compatible polymer blends  
The present invention pertains to products and processes relating to compatible polymer blends comprising at least one sulfonated polymer and at least one non-sulfonated polymer. The sulfonated...
8562966 End-modified poly(beta-amino esters) and uses thereof  
Poly(beta-amino esters) are end-modified to form materials useful in the medical as well as non-medical field. An amine-terminated poly(beta-amino ester) is reacted with an electrophile, or an...
8529922 Polymer formulations for delivery of bioactive materials  
PLGA, PLA and PGA polymers which have crystallinity resulting from the presence of long chain alkyl groups in terminal units. The polymers are particularly useful for drug delivery.
8530526 Biobeneficial coating compositions and methods of making and using thereof  
A biobeneficial coating composition for coating an implantable device, such as a drug eluting stent, a method of coating the device with the composition, and an implantable device coated with the...
8524784 Polymer micelles containing anthracylines for the treatment of cancer  
The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using...
8524368 Charge-dynamic polymers and delivery of anionic compounds  
The present invention provides dynamic charge state cationic polymers that are useful for delivery of anionic molecules. The dynamic charge state cationic polymers are designed to have cationic...
8524783 Polymer micelles containing anthracylines for the treatment of cancer  
The present invention provides micelles having an anthracycline encapsulated therein, the micelles comprising a multiblock copolymer. The invention further provides methods of preparing and using...
8512757 Micelles for drug delivery  
The invention provides a block copolymer comprising at least a first block and a second block. The first block comprises a plurality of temperature-sensitive monomeric units, a plurality of...
8496954 Coating systems for the controlled delivery of hydrophilic bioactive agents  
Described are coating systems for the controlled delivery of hydrophilic bioactive agents, for example, from implantable medical devices. The coating systems of the invention comprise (a) a...
8491929 Bioadhesive polymers  
Polymers and compositions, collectively “bioadhesive materials”, with improved bioadhesive properties have been developed. One or more compounds comprising: a) an aromatic moiety comprising two or...
8470891 Biodegradable block polymers for drug delivery, and methods related thereto  
A biodegradable block copolymer is disclosed, comprising a hydrophilic block derived from a polyether alcohol; and a hydrophobic block comprising a first repeat unit derived by ring opening...

Matches 1 - 50 out of 355 1 2 3 4 5 6 7 8 >