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9018222 Use of sodium channel blockers for the treatment of neuropathic pain developing as a consequence of chemotherapy  
The present invention refers to the use of sodium channel blockers such as tetrodotoxin or saxitoxin, its analogues/derivatives as well as their acceptable salts, for the production of a...
8993618 Composition for treating influenza A (H1N1) virus and a preparation method therefor  
New pharmaceutical compositions extracted from Ferula assa-foetida are confirmed to effectively treat influenza A (H1N1) virus. The extraction method of the new pharmaceutical compositions mainly...
8987324 Use of simalikalactone E as an anticancer agent  
The invention relates to Simalikalactone E (SkE) to be used for preventing and/or treating cancers.
8980940 Stable cannabinoid compositions and methods for making and storing them  
A composition comprising a high purity cannabinoid, an acid, and a pharmaceutically-acceptable solvent achieves room temperature stability for over 24 months. The acid improves the stability of...
8975236 Dietary supplement composition of citrus derivatives  
There is disclosed a dietary supplement composition of alkaloids and flavonoids extracted from citrus fruits that exhibits lipolytic and thermogenic activity and increases RMR, while at the same...
8974363 Topical medicaments and methods for photodynamic treatment of disease  
New photodynamic, topically-applicable medicaments and certain medical uses of such photodynamic medicaments for treatment of human or animal tissue are described, wherein a primary active...
8952054 Small molecule inhibitors of MUC1 and methods of identifying the same  
The invention provides methods for the identification of small molecules that inhibit MUC1 oligomerization, and the functions flowing therefrom. In addition, small molecules that prevent MUC1...
8952003 Sterol derivative  
The present invention provides a sterol derivative or a pharmaceutically acceptable salt thereof having an activity to promote proliferation of neural stem cells. Namely, the present invention...
8927598 Treating oncogenic Ras driven cancers  
Oncogenic Ras-driven cancer is treated with agent by interrupting pathway comprising activation of Akt by oncogenic Ras, activated Akt causing phosphorylation of eNOS at S1177 site of eNOS to...
8912229 Taxane and abeo-taxane analogs  
The present application discloses new taxane analogs, intermediates and methods for producing them. The present application is also directed to pharmaceutical formulations comprising abeo-taxanes...
8906956 Composition comprising (−)-Δ9-trans-tetrahydrocannabinol  
A composition comprising a tetrahydrocannabinol compound, a solvent and an acid, wherein the tetrahydrocannabinol compound may be Δ8 tetrahydrocannabinol, (−)-Δ9-trans-tetrahydrocannabinol or a...
8895605 Pyrrolidine-substituted flavones as radio-sensitizers for use in the treatment of cancer  
The present invention relates to a combination for the treatment of cancer wherein the combination exhibits a synergistic effect. The combination comprises radiation and at least one cyclin...
8895576 Methods of use of cyclopamine analogs  
The invention provides methods for treating various conditions using derivatives of cyclopamine having the following formula:
8889176 Method of managing or treating pain  
A composition for the intranasal delivery of fentanyl or a pharmaceutically acceptable salt thereof to an animal includes an aqueous solution of fentanyl or a pharmaceutically acceptable salt...
8883192 Compositions and methods for reducing or preventing obesity  
Compositions useful for weight management in an animal are disclosed. The compositions comprise one or more isoflavones or isoflavone metabolites, and in some embodiments include conjugated...
8865235 Microbicidal and antiparasitic compositions  
Pharmaceutical or dermo-dermo-cosmetic compositions for topical and intravaginal application for treatment of human and veterinary affections caused by anaerobic organisms or parasites comprising...
8859462 Pest control composition  
Disclosed is a pest control composition comprising at least one pyripyropene derivative of formula (I) or agriculturally and horticulturally acceptable salt thereof and at least one other pest...
8835448 Methods and formulations for modulating lyn kinase activity and treating related disorders  
The present invention relates to compounds and pharmaceutically acceptable salts thereof and formulations comprising the compounds or a pharmaceutically acceptable salts thereof that are useful in...
8835489 Compounds of the pterocarpanquinone family, method for preparing the same, pharmaceutical composition containing the new compounds of the pterocarpanquinone family, uses and therapeutic method  
This invention belongs to the chemical-pharmaceutical field. New compounds of pterocarpanquinone family presented in formula (I) according to this invention are capable to be activated by...
8815844 Mitochondrial activity inhibitors of cancer-initiating cells and use thereof  
The present invention relates to the compounds useful in the prevention and/or treatment of tumors. More specifically the present invention relates to inhibitors of the activity of the electron...
8796327 Method for inhibiting production of cytokines of T helper cell type II and/or inhibiting production of chemokines using brazilin  
A method for inhibiting the production of cytokines of T helper cell type II (Th2 cell) and/or inhibiting the production of chemokines in a mammal is provided, wherein the method comprises...
8778372 Dual-action pest control formulation and method  
The present disclosure provides a dual-action pest control formulation for controlling rodents and arthropods, the formulation including: a rodenticide; an insecticide; an optional attractant; and...
8778914 Bisphosphonate-prodrugs  
The present invention relates to a prodrug, comprising a pharmaceutically and/or diagnostically active compound, and one or more bisphosphonate groups, to a process for producing such a prodrug,...
8778988 Endoperoxides and methods of photocatalytically synthesizing endoperoxides  
A method of making an endoperoxide from a diene and oxygen in the presence of a photocatalyst having an excited state lifetime of at least 100 nanoseconds, the endoperoxide being represented by...
8765803 Rab7 GTPase inhibitors and related methods of treatment  
This invention relates to compounds and their use as inhibitors or activators of Rab7 GTPase to treat or prevent the onset of Rab 7 GTPase-associated disorders such as neuropathies, cancer,...
8758832 Oral or enteral dosage forms containing phytochemicals from pomegranates  
Nutraceutical compositions for improved administration of important phytochemicals from pomegranate to a human or animal. More particularly, enables oral or enteral dosage forms containing...
8722727 Antifungal agents  
Novel derivatives of enfumafungin are disclosed herein, along with' their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds,...
8716328 Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents  
The present application discloses an acid labile lipophilic molecular conjugate of cancer chemotherapeutic agents and methods for reducing or substantially eliminating the side effects of...
8709459 Triple-action pest control formulation and method  
The present disclosure provides a triple-action pest control formulation for controlling rodents, insects, and terrestrial mollusks, the formulation including: a first active ingredient which is a...
8686028 Substituted benzfurochromenes and related compounds for the prevention and treatment of bone related disorders  
The present invention relates to novel substituted benzfurochromenes and related compounds having the general formula (I), salts and chiral, achiral derivatives thereof; wherein R1, R2, R3, R4,...
8668921 Lipase inhibitors  
The present invention provides lipase inhibitors containing dimers of flavan-3-ols derived from teas as well as foods and beverages and medicines containing said inhibitors. More specifically, the...
8633203 Use of pterocarpans as active anti-cellulite ingredients  
The invention relates to a cosmetic, dermatological or pharmaceutical preparation, containing one, two or more compounds of formula (I) and/or a pharmaceutically acceptable salt of a compound of...
8623909 Prophylactic/therapeutic agents for lifestyle-related diseases  
Disclosed is a method for screening a compound having an activity that selectively modulates an androgen receptor, comprising a step of measuring the mRNA expression level of prostate-specific...
8623901 Compounds for the treatment of CNS disorders  
The invention relates to novel 1,6-disubstituted pyrazolopyrimidinones of formula (I), in which Hc is a tetrahydropyranyl-group and R1 is the group V−W−*, whereby V and W independently of each...
8618123 Benzenesulfonyl-chromane, thiochromane, tetrahydronaphthalene and related gamma secretase inhibitors  
Disclosed are novel gamma secretase inhibitors of the formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, wherein L1, n, X, Ar, Y, Z, Q, and Q1 are as defined herein....
8618161 Fluorescent polymeric materials containing lipid soluble rhodamine dyes  
Fluorescent polymeric materials are disclosed comprising a polymeric particle and one or more lipid soluble rhodamine dyes, comprising the following core structure: wherein R11 and R15 are each H...
8618125 Composition comprising hepatic therapeutic active for treating liver diseases, certain cancers and liver health maintenance  
Compositions of hepatic therapeutic actives from one or more acridone compounds, one or more xanthone compounds, one or more thioxanthone compounds, one or more tocotrienol compounds, and one or...
8586626 Metabolites of wortmannin analogs and methods of using the same  
Novel metabolites of wortmannin and wortmannin analogs and their use in inhibiting PI-3 kinase activity in mammals and the treatment and prevention of cancer or tumor formation in a subject are...
8580847 Antrocin containing pharmaceutical compositions for inhibiting cancer cells  
This subject invention is directed to a method for inhibition of cancer cells, comprising administrating an effective amount of a compound of formula I (Sesquiterpene lactones, antrocin) or...
8580772 Combination therapies using melengestrol acetate and zilpaterol or its salts  
This invention generally relates to a method for promoting growth and increasing feed utilization efficiency in animals, and, more specifically, to combinations comprising zilpaterol (and salts...
8575135 Antiviral compounds  
The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and...
8569378 p27 protein inducer  
The present invention provides a p27 protein inducing agent comprising a compound represented by general formula (11) below or pharmaceutically acceptable salt thereof as an active ingredient:...
8568794 Topical and intravaginal microbicidal and antiparasitic compositions comprising quassinoids or quassinoid-containing plant extracts  
Pharmaceutical or dermo-cosmetic compositions for topical and intravaginal application for treatment of human and veterinary affections caused by anaerobic organisms or parasites are provided...
8563600 Diagnostic compounds  
The Invention relates to conjugates of formula (III) or (IIIa), or a salt thereof, their use as radiopharmaceuticals, processes for their preparation, and synthetic intermediates used in such...
8563599 Methods for synthesizing glycinols, glyceollins I and II, compositions of selected intermediates, and therapeutic uses thereof  
Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are...
8551448 Rotanone analogs: method of preparation and use  
The present invention provides rotenone analogs and methods of making and using them. Labeled with single photon and positron emitting isotopes, the rotenone analogs of the present invention are...
8524214 Polyal drug conjugates comprising variable rate-releasing linkers  
Polyal-Drug conjugates comprising a variable rate-releasing linker are described along with methods of making such conjugates. Uses for such Polyal-Drug conjugates is also described.
8518915 Use of mitochondrially-addressed compounds for preventing and treating cardiovascular diseases  
The invention relates to pharmacology and medicine, in particular to a class of mitochondrially-addressed compounds which can be used in the pharmaceutical compositions of medicinal agents...
8476311 Composition for treating influenza A (H1N1) virus and a preparation method therefor  
New pharmaceutical compositions extracted from Ferula assa-foetida are confirmed to effectively treat influenza A (H1N1) virus. The extraction method of the new pharmaceutical compositions mainly...
8476312 Composition comprising (−)-Δ9-trans-tetrahydrocannabinol  
A composition comprising a tetrahydrocannabinol compound, a solvent and an acid, wherein the tetrahydrocannabinol compound may be Δ8 tetrahydrocannabinol, (−)-Δ9-trans-tetrahydrocannabinol or a...