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9034921 Diphenylmethane derivatives as SGLT2 inhibitors  
A compound with a diphenylmethane moiety having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney is disclosed. A...
8993618 Composition for treating influenza A (H1N1) virus and a preparation method therefor  
New pharmaceutical compositions extracted from Ferula assa-foetida are confirmed to effectively treat influenza A (H1N1) virus. The extraction method of the new pharmaceutical compositions mainly...
8986683 Combined use of ribonuclease and artemisinin  
The invention discloses a kit which comprises a formulation containing artemisinin or the derivatives thereof, a formulation containing ribonuclease, and a specification.
8987323 Crystalline form of benzylbenzene SGLT2 inhibitor  
Provided are crystalline forms of a compound having an inhibitory effect on sodium-dependent glucose cotransporter SGLT2. The invention also provides pharmaceutical compositions, methods of...
8962679 Daidzein analogs as treatment for cancer  
Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer...
8940301 Breast tumor treatment with anti-CXCR1 compositions  
The present invention provides methods of treating cancer by administering an IL8-CXCR1 pathway inhibitor (e.g., an anti-CXCR1 antibody or Repertaxin) alone or in combination with an additional...
8937097 Methods for purifying trans-(−)-Δ9-tetrahydrocannabinol and trans-(+)-Δ9-tetrahydrocannabinol  
Methods for making trans-(−)-Δ9-tetrahydrocannabinol and trans-(+)-Δ9-tetrahydrocannabinol are disclosed herein. In one embodiment, a trans-(−)-Δ9-tetrahydrocannabinol composition is prepared by...
8933116 Gamma secretase inhibitors  
Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims....
8927597 Compounds useful in the synthesis of halichondrin B analogs  
In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate....
8877715 Cytotoxic conjugates having neuropeptide Y receptor binding compound  
There is provided a series of novel neuropeptide Y-cytotoxic conjugates, compositions comprising the same, and methods relating to their therapeutic use for the treatment of disease or condition...
8865761 Regulation of cholesterol homeostasis  
The invention provides novel compounds of Formulas (I)-(IV), as described herein. Also provided are compositions of these compounds, method of making the compounds, and methods of using the...
8858991 Delayed release oral pharmaceutical dosage forms comprising MGBG  
Disclosed herein are controlled-release oral pharmaceutical dosage forms comprising MGBG, and their application for the improved treatment of diseases with reduced side effects and/or longer time...
8841264 Compositions  
Compositions containing a combination of hydroxytyrosol and resveratrol or liqustilide or (−)-epigallocatechin gallate or honokiol or genistein or Magnolia bark extract or a combination of...
8841290 Substituted tetrahydronaphthalenes, method for the production thereof, and use thereof as drugs  
Disclosed is a tetrahydronapthalene compound having Formula I the variables of which are as described herein, methods of preparing same and their use.
8829034 Compounds which modulate the CB2 receptor  
Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating...
8815941 2,3-fluorinated glycosides as neuraminidase inhibitors and their use as anti-virals  
Compounds of structural formula (I) useful for the treatment or prophylaxis of viral infection, particularly viral influenza are provided Pharmaceutical preparations thereof and methods for their...
8796327 Method for inhibiting production of cytokines of T helper cell type II and/or inhibiting production of chemokines using brazilin  
A method for inhibiting the production of cytokines of T helper cell type II (Th2 cell) and/or inhibiting the production of chemokines in a mammal is provided, wherein the method comprises...
8778988 Endoperoxides and methods of photocatalytically synthesizing endoperoxides  
A method of making an endoperoxide from a diene and oxygen in the presence of a photocatalyst having an excited state lifetime of at least 100 nanoseconds, the endoperoxide being represented by...
8748484 Organometallic anti-cancer complexes  
An anti-cancer ruthenium complex containing organometallic triruthenium with two maltol ligands is claimed.
8633182 Indanyloxyphenylcyclopropanecarboxylic acids  
The present invention relates to compounds of general formula I, wherein the groups R1, R2, R3, m and n are defined as in claim 1, which have valuable pharmacological properties, in particular...
8633026 Cytokine induction of selectin ligands on cells  
Methods and compositions for treating cells with cytokines are provided herein.
8623912 Fostriecin derivatives and the pharmaceutical uses thereof  
Novel Fostriecin (or FST) derivatives represented by formula (I), the pharmaceutical compositions and preparation methods thereof. The pharmaceutical uses of these compounds, especially the use...
8580846 Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders  
The invention is directed to a method of preventing or ameliorating a neuropsychiatric or neurodegenerative disease or disorder in a subject. The method includes administering a composition...
8569362 Polyketide molecules as anticancer agents  
The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) alkyl group, as well as...
8557874 Hemostatic material  
The present invention relates to hemostatic fabric materials, and to the methods for making and using such materials. In particular, the present invention relates to hemostatic fabric materials...
8524214 Polyal drug conjugates comprising variable rate-releasing linkers  
Polyal-Drug conjugates comprising a variable rate-releasing linker are described along with methods of making such conjugates. Uses for such Polyal-Drug conjugates is also described.
8513300 Formulations for oral administration of cromolyn sodium  
An oral dosage form comprises cromolyn sodium (sodium or disodium cromoglycate), and an acylated amino acid delivery agent.
8476311 Composition for treating influenza A (H1N1) virus and a preparation method therefor  
New pharmaceutical compositions extracted from Ferula assa-foetida are confirmed to effectively treat influenza A (H1N1) virus. The extraction method of the new pharmaceutical compositions mainly...
8476314 Substance with sedative effect  
A substance with sedative effect comprises a therapeutically effective amount of a gamma-pyrone such as comenic acid in a pharmaceutically acceptable carrier. When administered at a daily dosage...
8470874 Pharmaceutical compositions comprising cannabichromene type compounds  
The invention relates to the use of cannabichromene type compounds and derivatives thereof in the treatment of mood disorders.
8410165 Aldehyde conjugated flavonoid preparations  
There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8...
8404740 Spirocyclic cyclohexane compounds  
Spirocyclic cyclohexane compounds corresponding to formula I In which R1, R2, R3 and R5 through R10 and X have defined meanings, a process for their preparation, pharmaceutical compositions...
8399509 Glucopyranoside derivatives  
Novel compounds of the formula (I), in which X has the meaning indicated in Patent Claim 1, are suitable as antidiabetics.
8377930 PDE10 inhibitors and related compositions and methods  
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological...
8372879 4-(heterocycloalkyl) benzene-1,3-diol compounds as tyrosinase inhibitors, process for the preparation thereof and use thereof in human medicine and also in cosmetics  
4-(heterocycloalkyl)benzene-1,3-diol compounds are described corresponding to general formula (I) below: Also described, are compositions including the same, processes for preparation thereof and...
8367652 Methods of treating hypertriglyceridemia  
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising...
8367708 Phenyl-isoxazol-3-ol derivative  
The present invention relates to a compound represented by formula (I), which has a GPR120 agonist action and thus is useful for treatment of diabetes mellitus or hyperlipidemia, or a...
8357677 Methods of treating hypertriglyceridemia  
In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising...
8343995 Formulations containing clopidogrel and sulfoalkyl ether cyclodextrin and methods of use  
The present invention provides compositions containing clopidogrel, present as a free base or a pharmaceutically acceptable salt thereof, and sulfoalkyl ether cyclodextrin (SAE-CD). The...
8314140 4-hydroxythiobenzamide derivatives of drugs  
Derivatives of drugs are provided, said derivatives comprising the H2S-releasing moiety 4-hydroxythiobenzamide that is either covalently linked to the drug or forms a salt with the drug. The...
8309118 Film forming compositions containing sucralose  
Water soluble, gelatin-free dip coatings for substrates comprising a hydrocolloid, such as carrageenan, and sucralose.
8288378 Phosphoinositide modulation for the treatment of neurodegenerative diseases  
The present invention relates to the use of agents that inhibit the toxic effects of amyloid oligomers by increasing intracellular levels of phosphoinositol 4-phosphate (PI(4)P, or “PIP”) and/or...
8193239 Substituted 1-cyanoethylheterocyclylcarboxamide compounds  
The present invention provides compounds of formula (I) in which y, m, n, R1, R2 and Q are as defined in the specification, a process for their preparation, pharmaceutical compositions containing...
8187825 Thiol detection method  
It is an object of the present invention to provide: a novel thiol-detecting reagent, which can be used in vivo and which solves the problem regarding the generation of background fluorescence due...
8183213 Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators  
Combination therapy comprising RXR modulators and glucose reabsorption inhibitors useful for the treatment of diabetes and Syndrome X are disclosed.
8183233 Stable pharmaceutical formulations  
Stable pharmaceutical formulations and methods of making same are provided. In a general embodiment, the present disclosure provides a method of making a stable pharmaceutical formulation...
8158677 Treatment of viral infections by modulation of host cell metabolic pathways  
Alterations of certain metabolite concentrations and fluxes that occur in response to viral infection are described. Host cell enzymes in the involved metabolic pathways are selected as targets...
8148423 Fluorophore compounds  
Provided herein are fluorophore compounds including rhodol and rhodamine compounds which can be used as fluorescent labels and/or fluorogenic probes and methods of making same. Provided also...
8138163 Aldehyde conjugated flavonoid preparations  
There is provided a method of conjugating a polymer containing a free aldehyde group with a flavonoid in the presence of an acid catalyst, such that the polymer is conjugated to the C6 or C8...
8119695 Compounds and methods for treating breast cancer and other diseases  
Disclosed are novel compositions and novel methods for the creation of both the novel compounds and known compounds. Also disclosed are methods for use of the novel compounds for treating a...

Matches 1 - 50 out of 418 1 2 3 4 5 6 7 8 9 >