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9028853 Pathogen protection garment with both rapid and persistent rechargable self-sterilization  
A moisture-permeable glove or other garment protects against user contamination and cross-contamination by providing both rapid and persistent sterilization. Exposure to halogen of inherent NH...
9023879 Specific diarylhydantoin and diarylthiohydantoin compounds  
Compositions, such as pharmaceutical compositions, comprising specific diarylhydantoin and diarylthiohydantoin compounds, or salts or solvates thereof, are provided. Isolated and purified forms of...
9018239 Treatment of edible crops  
In the growing of crops for consumption, a method for the removal of pathogens includes the addition to irrigation water for the crops of an anti-pathogen composition and supplying the...
8975284 Co-solvent compositions and methods for improved delivery of dantrolene therapeutic agents  
The present invention provides for methods of using tert-butyl alcohol (TBA) co-solvent systems in the formulation and production of a pharmaceutical agent with low solubility. The present...
8957083 Spiro-amino-imidazolone and spiro-amino-dihydro-pyrimidinone compounds as beta-secretase modulators and methods of use  
The present invention provides a new class of compounds useful for the modulation of beta-secretase enzyme (BACE) activity. The compounds have a general Formula I: wherein variables A1, A3, A4,...
8895036 Topical compositions to treat circulatory disorders  
The invention relates to transdermal compositions including nifedipine, pentoxifylline, ketamine hydrochloride, gabapentin, lidocaine, and prilocaine that may be used to treat conditions such as...
8894986 Wound healing compositions including cyanoacrylate monomers and phenytoin  
A monomeric adhesive composition includes a stabilized polymerizable monomer, such as a 1,1-disubstituted monomer, including a cyanoacrylate, and a wound healing agent, wherein the wound healing...
8859529 Compounds for the treatment of inflammatory disorders  
This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or...
8765757 3-heterocyclic substituted indole derivatives and methods of use thereof  
The present invention relates to 3-Heterocyclic Substituted Indole Derivatives, compositions comprising at least one 3-Heterocyclic Substituted Indole Derivative, and methods of using the...
8759384 Oxo-imidazolyl compounds  
Compounds represented by Formula I and II, or pharmaceutically acceptable salts thereof: inhibit bacterial 2-epimerase and are useful anti-infective agents.
8729096 Imidazolidine-2,4-dione derivatives as N-formyl peptide receptor 2 modulators  
The present invention relates to novel imidazolidine-2,4-dione derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators...
8710091 Imidazolidine-2,4-dione derivatives, and use thereof as a cancer drug  
The present application relates to novel imidazolidine-2,4-dione derivatives of the general formula (I), where R1, R2, R3, R4, X, and Y are variables. Said materials have an antiproliferative...
8685460 Treatment using dantrolene  
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH)...
8663663 Topical compositions to treat circulatory disorders  
The invention relates to transdermal compositions including nifedipine, pentoxifylline, ketamine hydrochloride, gabapentin, lidocaine, and prilocaine that may be used to treat conditions such as...
8648105 Diarylthiohydantoin compounds  
The present invention relates to diarylthiohydantoin compounds and methods for synthesizing them and using them in the treatment of hormone refractory prostate cancer.
8628788 Formulations containing a non-oxidative biocide and a source of active halogen and use thereof in water treatment  
Novel formulations containing a non-oxidative biocide, such as DBNPA, and a source of an in situ produced active biocide, such as a concentrated aqueous solution of an inorganic halide salt, are...
8604072 Treatment using dantrolene  
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH)...
8552023 Non-amidic linkers with branched termini as CGRP receptor antagonists  
The present invention is directed to novel non-amidic linkers with branched termini derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in...
8541458 Oxabicycloheptanes and oxabicycloheptenes, their preparation and use  
This invention provides compounds having the structure which may be used for the treatment of tumors.
8536212 Protective agent for retinal nerve or optic nerve  
The present invention provides a protective agent for retinal nerve or optic nerve which exerts its effect through a different mechanism from that of conventional therapeutic agents and can be...
8524755 Specific diarylhydantoin and diarylthiohydantoin compounds  
Compositions, such as pharmaceutical compositions, comprising specific diarylhydantoin and diarylthiohydantoin compounds, or salts or solvates thereof, are provided. Isolated and purified forms of...
8496920 N-halamine acrylamide monomers and copolymers thereof for biocidal coatings  
Novel acrylamide and methacrylamide hydantoin monomers which can be reacted with other acrylamide, methacrylamide, acrylate, and methacrylate monomers to form copolymers, which upon halogenation,...
8492419 Multifunctional solid formulations for water conditioning  
Solid formulations for use in water conditioning of circulating reservoirs, processes of preparing same and methods for water conditioning utilizing same are disclosed. The solid formulations...
8426456 Fungicidal control of moulds  
A composition for treating fungus infection of turfgrass, such as snow mold infection, comprises a mixture of fungicidally effective amounts of formulae 1 and 2: and in particular mixtures of...
8420683 5 substituted hydantoins  
The present invention relates to 5-substituted hydantoins, a process for the preparation of 5-substituted hydantoins and the use of 5-substituted hydantoins in the preparation of enantiomerically...
8377979 Pharmaceutical formulation containing phenytoin sodium and magnesium stearate  
The present invention relates to a novel pharmaceutical formulation comprising phenytoin sodium, a high amount of magnesium stearate, and a low level of a hydrophilic polymer such as a methocel,...
8372876 Method for improving memory in mammals  
A method for improving memory in healthy subjects is disclosed. This method makes use of melatonin receptor antagonists such as luzindole and/or K-185 to reverse the inhibitory effect of...
8324259 Fungical control of moulds  
A composition for treating fungus infection of turfgrass, such as snow mould infection, comprises a mixture of fungicidally effective amounts of formulae 1 and 2: and in particular mixtures of...
8227473 Oxabicycloheptanes and oxabicycloheptenes, their preparation and use  
This invention provides compounds having the structure which may be used for the treatment of tumors.
8217068 Compound with anesthetics activity, methods for its production and pharmaceutical compositions comprising the same  
The present invention is related to a new series of chemical compounds, namely 3-benzyl-imidazolidine-2,4-dione substituted in the position 2 and/or 6 of benzyl ring by halogens as presented to...
8193227 HIV protease inhibiting compounds  
A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
8188130 Anti-cancer hydantoin compounds and methods  
The present invention relates to methods of either treating or preventing cancer and novel compositions relevant to that treatment and prevention. More particularly, this invention relates to...
8168666 Substituted carbinol compound  
There is provided a novel LXRβ agonist useful as a preventative and/or therapeutic agent for arteriosclerosis; arteriosclerosis such as those resulting from diabetes; hyperlipidemia;...
8168667 Imidazolidine derivatives, uses therefor, preparation thereof and compositions comprising such  
Compounds of formula (I): wherein X is O or S,R1 is acyl, aldehyde, cycloalkyl, an optionally substituted alkyl, alkenyl or alkynyl,R2 is H, alkyl, hydroxyalkyl, haloalkyl, alkenyl, or alkynyl;...
8153634 Carbinol derivatives having cyclic linker  
[Object] To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia;...
8153673 Metalloproteinase inhibitors  
Compounds of the formula (I) wherein Z is SO2(N6) or N(R7)SO2 or N(R7)SO2N(R6) useful as metalloproteinase inhibitors, especially as inhibitors of MMP12.
8148390 Monocyclic anilide spirolactam CGRP receptor antagonists  
The present invention is directed to compounds of Formula I: (where variables A1, A2, B, J, K, m, n, R4, R5a, R5b and R5c are as defined herein) useful as antagonists of CGRP receptors and useful...
8110225 Treatment using dantrolene  
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH)...
8097640 Prophylactic or therapeutic agent for diabetic maculopathy  
A prophylactic or therapeutic agent for diabetic maculopathy, which can be administered for a long time and exhibits efficacy in a mechanism different from that of existing medicines. The...
8063085 Substituted hydantoins  
The present invention relates to compounds of the formula methods for the preparation thereof, and methods for their use. The compounds are useful in treating diseases characterized by the...
8044082 N-phenylacetamide inhibitors of the enzyme SOAT-1 and pharmaceutical/cosmetic compositions comprised thereof  
Novel N-phenylacetamide compounds of formula (I): and cosmetic and pharmaceutical compositions containing same are useful for treating disorders of the sebaceous gland, e.g., acne, or have...
8039499 Ester compound and its use  
An ester compound represented by the formula (I): (wherein, R1 represents a C1-C3 alkyl group, a 2-propenyl group or a 2-propynyl group.) has excellent pest controlling activity and is useful as...
8022092 (2,5-dioxoimidazolidin-1-yl)-N-hydroxy-acetamides as metalloproteinase inhibitors  
The invention provides compounds of the formula (I) wherein the variables are as defined in the specification. The compounds of the invention are inhibitors of metalloproteinase MMP-12 and are...
7985413 Microbiological control in aqueous systems  
Microbiological control is achieved by continuously and inexpensively dosing water in contact with biofilm, or that comes into contact with biofilm, using a highly effective biocide that provides...
7973067 Heterocyclic aspartyl protease inhibitors  
Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W is a bond, —C(═S)—, —S(O)—, —S(O)2—, —C(═O)—, —O—,...
7951822 1,3-dihydroisobenzofuran derivatives  
The object is to provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia;...
7943389 Method for determining chlorine demand in water  
Methods for determining chlorine demand in water are provided. One method comprises (a) providing a test water sample containing at least one contaminant and a source of chlorine and a source of...
7923036 Halogen-containing sanitizing composition  
Compositions comprising a mixture of (a) a major amount of solid halogen-containing sanitizer material and (b) a minor amount of calcium oxide modified particulate boric acid, the amount of...
7919509 2-oxochromene derivatives  
To provide a novel LXRβ agonist that is useful as a preventative and/or therapeutic agent for atherosclerosis; arteriosclerosis such as those resulting from diabetes; dyslipidemia;...
7910615 Prophylactic or therapeutic agent for diabetic maculopathy  
A prophylactic or therapeutic agent for diabetic maculopathy, which can be administered for a long time and exhibits efficacy in a mechanism different from that of existing medicines. The...

Matches 1 - 50 out of 273 1 2 3 4 5 6 >