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9034588 Monoclonal antibody therapy for pancreas cancer  
The present invention relates to the use of binding equivalents of monoclonal antibody 31.1, including chimerized and/or humanized versions thereof, antibody fragments as well as competitively...
9034587 Methods of diagnosing cancer  
A method of diagnosing cancer or a pre-malignant lesion is disclosed. The method comprises determining a level of CD24 expressed on peripheral blood cells of a subject in need thereof, wherein the...
9023999 Anti-CD27 antibody  
The present invention provides a monoclonal antibody which specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to its extracellular region, or...
9023605 Antibodies and molecules derived therefrom that bind to STEAP-1 proteins  
Antibodies and molecules derived therefrom that bind to novel STEAP-1 protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and...
9017951 Anti-FcRH5 antibodies and immunoconjugates and methods of use  
A method of determining the presence of FcRH5 in a biological sample suspected of containing FcRH5 is provided comprising exposing the biological sample to an isolated monoclonal anti-FcRH5 antibody.
9018351 Peptide aptamers against tenascin C  
The present invention relates to an anti-tenascin C peptide aptamer having a specific amino acid sequence and a diagnosis kit comprising it. The anti-tenascin C peptide aptamer of the instant...
9005907 Methods and compositions for typing molecular subgroups of medulloblastoma  
Immunohistochemical methods and compositions for the typing of molecular subgroups of medulloblastomas are provided. The methods comprise determining a protein expression profile for a sample...
9005994 Methods for biomolecule and biomolecule complex (BMC) detection and analysis and the use of such for research and medical diagnosis  
The present application pertains to improved methods of detecting biomolecules in a biological sample (or system), In particular, embodiments discussed herein allow for the detection of...
9006396 CsPCNA isoform antibodies and uses thereof  
Antibodies specifically bind only to a cancer specific proliferating cell nuclear antigen (csPCNA) isoform and not to the non-malignant proliferating cell nuclear antigen (nmPCNA) isoform. Methods...
8999657 Reagents, methods, and kits for the classification of cancer  
Reagents, methods, and kits for the classification of cancer that comprise or employ antibodies that bind specific regions of CD43. One method includes contacting tissue with an antibody capable...
8999656 PODXL protein in colorectal cancer  
The present disclosure provides a method for determining whether a mammalian subject having a colorectal cancer belongs to a first or a second group, wherein the prognosis of subjects of the first...
8999647 Methods of subclassification of ductal carcinoma in situ of the breast  
Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal...
8999655 Increase of myeloid microvesicles in the cerebrospinal fluid as biomarker of microglia/macrophage activation in neurological disorders  
The present invention relates to a method for the diagnostic and/or prognostic of a neurological disease characterized by an inflammation process in a subject comprising measuring the amount of...
8999334 Antibody conjugates against variant NFKBIB and uses thereof  
The present application provides the amino acid and nucleic acid sequences of heavy and light chain complementarity determining regions of a cancer specific antibody directed to an epitope of...
8993278 Conjugates for cancer therapy and diagnosis  
The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof....
8993251 Genes from 20q13 amplicon and their uses  
The present invention relates to cDNA sequences from a region of amplification on chromosome 20 associated with disease. The sequences can be used in hybridization methods for the identification...
8995740 System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue  
Improved systems and methods for the analysis of digital images are provided. More particularly, the present disclosure provides for improved systems and methods for the analysis of digital images...
8993728 Anti-human CLCP1 antibody and use thereof  
The present invention provides novel antibodies that recognize the extracellular domain of a human CLCP1 antigen; nucleic acids encoding the antibodies; vectors carrying the nucleic acids in an...
8993309 Predictive marker for topoisomerase I inhibitors  
The present invention generally relates to the fields of cancer therapy and cancer prevention. More particularly, the present invention generally relates to a diagnostic marker for predicting the...
8987423 MAGE antigen binding proteins  
Antigen binding proteins, such as antibodies, which bind to human MAGE-A3, polynucleotides encoding such antigen binding proteins, and uses and manufacture thereof.
8987004 Nanostructures for polarized imaging and receptor/ligan quantization: breaking the diffraction limit for imaging  
The present invention relates to affinity biosensing using polarization of light scattering of aggregated noble metallic nanostructures to determine concentration of an analyte in a test sample....
8980638 Use of IMP3 as a prognostic marker for cancer  
Provided herein are methods and compositions for the prognostic evaluation of a patient suspected of having, or having, cancer by assessing the expression of IMP3 in a biological sample of a...
8980565 Porphyrinic compounds for use in flow cytometry  
The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The...
8980570 Composition for cancer prognosis prediction comprising anti-TMAP/CKAP2 antibodies  
The present invention relates to an antibody which specifically binds to TMAP (tumor associated microtubule associated protein)/CKAP2 (cytoskeleton associated protein 2) or a fragment thereof, and...
8980548 Methods and reagents for metabolomics and histology in a biological sample and a kit for the same  
A method of extracting and measuring one or more biochemicals from a biological sample, comprises immersing the biological sample in an organic solvent, whereby one or more biochemicals present in...
8980569 Chronic lymphocytic leukemia prognosis and treatment  
Provided herein are methods for identifying a subject afflicted with chronic lymphocytic leukemia who is responsive to treatment with a chemotherapeutic agent by detecting the presence or absence...
8975037 Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells  
The invention provides compositions comprising one or more isolated factors from a microenvironment of human embryonic stem cells (hESCs), including, but not limited to, Lefty and inhibitors of...
8975038 Method for determining presence of carcinomic cells with 5, 10, 15, 20-tetrakis (carboxyphenyl) porphine  
Presented is a method of determining the presence of carcinomic cells in a sample by contacting a sample of cells with a solution of TCPP to permit binding of the TCPP to components of the...
8975036 Methods for improved diagnosis of dysplasias  
The present invention relates to a method for improved diagnosis of dysplasias based on simultaneous detection of INK4a gene products and at least one marker for cell proliferation. Particularly...
8968995 Detection, screening, and diagnosis of HPV-associated cancers  
Embodiments of the invention provide methods, polyclonal antibodies, monoclonal antibodies, assays, and kits for detecting HPV infection, including infection by various HPV genotypes, early and/or...
8969021 Methods and compositions for detecting non-hematopoietic cells from a blood sample  
The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells, especially tumor cells, from a complex fluid sample such as a blood...
8969020 Peptide sequence that promotes tumor invasion  
An isolated sequence SGSSEEKQNAVSSEET (OPNcPEP) SEQ ID NO: 8, and uses thereof. The peptide enhanced soft agar clone formation but did not support the growth of cells in plastic dishes, consistent...
8969012 Immunogens for treatment of neoplastic and infectious disease  
The present invention relates to prophylactic and therapeutic methods of immunization against neoplastic and infectious diseases. The invention provides a method for identification of novel...
8969100 Method for detecting afferent lymph vessel inflow regions and method for identifying specific cells  
Regions where metastatic cancer cells can exist are detected with high accuracy in a sentinel lymph node. Quantum dots are injected into the vicinity of a cancer in a living body, thereby...
8962263 Methods and compositions for detecting the activation state of multiple proteins in single cells  
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
8962258 Apparatus and method for multiple immunoassays on a chip  
Provided are a multiple immunoassay apparatus on a chip in which a structure comprising multiple microfluidic channels is associated with a tissue sample, which allows immunohistochemical...
8956820 Method for detecting cancer cells using vertically aligned carbon nanotubes  
The various embodiments herein provide a method for detecting the cancerous cells using the carbon nanotubes. The method comprises preparing a solution of the tissue cells. The prepared solution...
8956822 Method for predicting the response to HER2-directed therapy  
This invention provides methods for determining or predicting response to HER2-directed therapy in an individual.
8951484 Circulating tumor cell capturing techniques and devices  
Candidate cells, such as circulating tumor cells (CTCs), present with blood are captured using a multiple stage device, having successive stages configured to deviate candidate cells out of the...
8951526 Antibody against mucin 1 (MUC1) protein and use of same  
The present invention provides means and a method assuring the effectiveness of early diagnosis of cancers including gastric cancers. Specifically, the present invention provides an antibody,...
8951744 Nucleic acid and corresponding protein named 158P1D7 useful in the treatment and detection of bladder and other cancers  
The invention described herein relates to novel nucleic acid sequences and their encoded proteins, referred to as 158P1D7 and variants thereof, and to diagnostic and therapeutic methods and...
8951737 Treatment and diagnosis of cancer  
Use of antibodies or binding portions thereof, probes, ligands, or other biological agents which either recognize an extracellular domain of prostate specific membrane antigen (PSMA) or bind to...
8951746 Method and devices for screening cervical cancer  
The present invention provides multi-parameter analysis methods for determining the presence or absence of pre-cancerous or cancerous cells in a cervical sample and for screening cervical...
8951738 CYBP as a marker for lung cancer  
The present invention relates to the assessment of lung cancer. It discloses the use of protein CYBP in the assessment of lung cancer. It also relates to a method for assessing lung cancer in...
8946379 Bladder cancer specific ligand peptides  
The present invention is directed to bladder cancer specific ligand peptides, comprising the amino acid sequence X1DGRX5GF (SEQ ID NO:1), and methods of their use, e.g., for imaging detection for...
8946169 SPARC and methods of use thereof  
The invention provides methods for predicting or determining the response of a mammalian tumor to a chemotherapeutic agent and for treating a mammalian tumor comprising detecting and quantifying...
8940497 Enzyme regulating ether lipid signaling pathways  
A multidimensional profiling strategy that combines activity-based proteomics and metabolomics was used to determine that an active protein, which is a previously uncharacterized enzyme highly...
8940488 Cancer diagnosis and treatment of cancer using anti-robo 1 antibody  
A method for diagnosing cancer comprising detecting ROBO1 protein is disclosed. In addition, a method for treating a disease caused by abnormal cell growth comprising administrating an antibody...
8940298 High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection  
The present invention provides novel high affinity antibodies and fragments thereof that bind to the cancer antigen PSCA. The antibodies of the present invention may be used for cancer diagnosis,...
8940493 Circulating tumor cell assay  
Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer...