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9040304 |
Multi-channel system and methods for sorting particles
A multi-channel system and methods for sorting particles according to one or more characteristics of the particles. The system includes multiple flow cytometry units, each unit can have a nozzle... |
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9034922 |
Composition for maintaining function of platelets
A composition for maintaining a function of platelets, the composition comprising, as an active ingredient, a compound represented by the following general formula (I) or a salt thereof, or a... |
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9029079 |
Method of biotechnological production of bovine hemoderivative
A method of biotechnological production of a bovine hemoderivative comprising the steps of: freshly acquired animal blood matter is first fermented in several phases, the blood fermentation... |
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9023613 |
Sperm selecting system and the method thereof
The present invention discloses a sperm selecting system and the method thereof. The brief concept of the present invention is to generate a flow field by hydraulic pressure difference then... |
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9012134 |
CD127 expression inversely correlates with FoxP3 and suppressive function of CD4+ Tregs
The invention provides methods of isolating CD127lo/− immunosuppressive regulatory T cells which can be greatly enriched for FoxP3, methods of expanding the isolated cells, pharmaceutical... |
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9012135 |
Methods, reagents and kits for preservation of nucleic acids in biological samples
Provided is a nucleic acid preservative comprising at least one reducing agent, at least one chaotropic substance, at least one polyamine substance and at least one chelating agent and uses... |
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9011867 |
Use of specific peptides in the preparation of a medicament for the treatment of monoclonal gammopathy of undetermined significance (MGUS) or of smoldering multiple myeloma (SMM)
The present invention relates to the use of a peptide comprising or essentially consisting of a sequence motif as shown in SEQ ID NO: 1 for the preparation of a medicament for the treatment of... |
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9005886 |
Method for cryopreservation of human spermatozoa free from seminal plasma using a fast and simple aseptic vitrification-devitrification process; portable kit for carrying out the method; and use of the same for treatment of disorders related to reproductive failures
The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification... |
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9005343 |
Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein... |
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8999632 |
Method for measuring ATR inhibition mediated increases in DNA damage
The present relates to methods for detecting DNA damage in subjects treated with an ATR inhibitor. More specifically, this invention relates to a method for measuring changes in levels of γH2AX... |
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8980542 |
Arginine-containing compositions and methods for treating red blood cells
Blood storage and/or rejuvenating compositions that include D-ribose and an arginine (e.g. L-arginine, D-arginine, or a combination thereof) are disclosed herein. Such compositions can be useful... |
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8979770 |
Extraction and diagnostic fluid devices, systems and methods of use
The present invention provides devices, systems and methods for RNA isolation from biological samples containing white blood cells, such as whole blood. The devices have a device body that... |
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8968391 |
Systems and methods to reduce gel retraction
Methods for ameliorating stent graft migration and endoleak using treatment site-specific cell growth promoting compositions in combination with stent grafts are disclosed. Also disclosed are... |
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8968993 |
Method of blood pooling and storage
The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from a plurality of blood units, and... |
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8969073 |
Device and method for isolating cells, bioparticles and/or molecules from liquids
The invention describes an appliance and a method, with the help of which specific bio-particles, but also dissolved bio-molecules can be recognized in and separated from fluids making use of... |
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8968991 |
Integrated system for on-site mononuclear cell acquisition, processing and delivery
Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate... |
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8969533 |
Formulation of sugar solutions for continuous ultracentrifugation for virus purification
The present invention provides a method for purification of a virus or virus antigen comprising providing a virus preparation and centrifugation of said virus preparation in a gradient of a sugar... |
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8968992 |
Red blood cell storage medium for extended storage
Synthetic aqueous storage solutions are disclosed for use in the processing and the storing of red blood cells prepared from whole blood including cells derived from whole blood held for an... |
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8962235 |
Capillary transport
A method for sorting particles, in particular cells A and B. The method uses a single channel with only one input and only one output. A particle mix A and B in a fluid is introduced into the... |
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8951484 |
Circulating tumor cell capturing techniques and devices
Candidate cells, such as circulating tumor cells (CTCs), present with blood are captured using a multiple stage device, having successive stages configured to deviate candidate cells out of the... |
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8951719 |
Matrices and media for storage and stabilization of biomolecules
The present invention provides compositions useful for biomolecule storage comprising a water soluble inorganic compound, a stabilizer, or a combination thereof. The present invention also... |
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8951782 |
Apparatus for separating cells using magnetic force and cell separation method using the same
An apparatus for separating cells using magnetic force includes: a separation channel portion including ferromagnetic particles, and provided with a flow path through which a cell fluid containing... |
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8945857 |
Methods of isolating cells and generating monoclonal antibodies
The invention provides methods for isolating cells, particularly antibody-secreting cells that have a high likelihood of secreting antibodies specific for a desired antigen for the purpose of... |
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8936905 |
Systems and methods for cryopreservation of cells
An auto-nucleating device includes a tube containing a crystalline cholesterol matrix. The ends of the tube are closed by a membrane impermeable to the cholesterol but permeable to liquids... |
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8936162 |
Collection tubes apparatus, systems and methods
Methods of producing collection tubes are presented. The methods include providing a separator substance that can rapidly polymerize in a short time to a desired hardness and disposing the... |
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8932470 |
Filter material for removing aggregates and method of filtering blood product
An aggregate-removing filter material efficiently removes aggregates that are contained in a blood product for transfusion and may cause transfusion reactions without clogging, and exhibits... |
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8927203 |
Platelet preservation package comprising a short to ultra-short acting antiplatelet agent and anticoagulant
The present invention relates to compositions and methods for storing platelets to preserve the function and freshness of the platelets. More particularly, the present invention relates to the use... |
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8928884 |
Validation method for automated analyzers
Method for validating the accuracy of automated analyzers by performing an improved dye method procedure that uses at least first and second dye solutions in combination with gravimetric... |
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8921037 |
PF4-depleted platelet rich plasma preparations and methods for hard and soft tissue repair
Methods of repairing and regenerating hard or soft tissue and reducing inflammation, anti-angiogenesis and anti-osteogenesis in a mammal and related methods of removing PF4 from platelets... |
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8920659 |
Component preparation system
Disclosed herein are centrifuge-free self-contained systems for aseptically separating components of whole blood comprising at least one cassette for receiving whole blood; at least one red blood... |
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8921102 |
Devices and methods for enrichment and alteration of circulating tumor cells and other particles
The invention features devices and methods for detecting, enriching, and analyzing circulating tumor cells and other particles. The invention further features methods of diagnosing a condition,... |
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8911789 |
Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
Blood-derived plastic articles prepared from compositions including blood and, in some embodiments, at least one crosslinking agent and/or at least one biological response modifier, that can be... |
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8900805 |
Quenching methods for red blood cell pathogen inactivation
The present invention provides improved methods for treating red blood cell compositions with a pathogen-inactivating compound under conditions which provide suitable pathogen inactivation while... |
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8900806 |
Antibody preparations
An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5% IgM antibodies by weight of the total amount of antibodies. The preparation is prepared... |
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8895298 |
Microfluidic device for cell separation and uses thereof
The invention features methods for separating cells from a sample (e.g., separating fetal red blood cells from maternal blood). The method begins with the introduction of a sample including cells... |
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8895236 |
Composition for cryopreservation comprising nicotinamide, glycerol and red blood cells
A red blood cell storage composition includes a composition of red blood cells and biochemistry altering reagents, the biochemistry altering reagents being present at a concentration so as to... |
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8889124 |
Tolerogenic populations of dendritic cells
Tolerogenic populations of dendritic cells are provided, where the dendritic cells are characterized by expression of select tissue-specific homing receptors including the chemokine receptors... |
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8883409 |
Method of reducing pathogens in whole blood by illuminating with ultraviolet light under low oxygen conditions
Disclosed are methods for pathogen reduction in blood by illuminating with UV light while taking steps for preservation of blood components and reducing oxidative damage from reactive oxygen... |
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8871228 |
Injectable composition containing hydroxychloroquine for local administration for treating hemorrhoids
The present invention relates to an injectable composition for local administration for treating hemorrhoids, which contains hydroxychloroquine. Specifically, the composition contains a solution... |
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8871434 |
Red blood cell storage medium for extended storage
Synthetic aqueous storage solutions are disclosed for use in the processing and the storing of red blood cells prepared from whole blood including cells derived from whole blood held for an... |
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8865420 |
Methods and compositions for risk stratification
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of... |
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8865172 |
Method for reducing the number of unwanted molecules in bodily fluids
A method for reducing the number of selected antibodies in a subject's blood, the method comprising removing blood from the subject, passing the blood along an enclosed pathway, wherein the... |
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8859840 |
Multiple-use blood blotting devices for diabetics for use when monitoring blood glucose levels
A multiple-use blotting device for blotting blood from a fingertip includes a substrate, and a blood absorbing pad secured to the substrate. The blood absorbing pad has a plurality of blood... |
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8859278 |
Fully human hybridoma fusion partner cell lines
Certain aspects of the present invention are directed to new fully human fusion partner cell lines called human Karyochi cells, and to methods for making them. Human Karyochi cells are then fused... |
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8846333 |
Method and device for visual detection of hemolysis
The present invention relates to a device for visual detection of hemolysis in a whole blood sample, comprising at least one visible detection compartment and a transfer passage connected to said... |
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8835104 |
Medium and methods for the storage of platelets
Synthetic storage media are disclosed for use in the processing and the storing of platelets. The storage media includes a platelet storage solution and less than 20 percent plasma to preserve... |
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8815537 |
Method for determining a complete blood count on a white blood cell differential count
Systems and methods analyzing body fluids such as blood and bone marrow are disclosed. The systems and methods may utilize an improved technique for applying a monolayer of cells to a slide to... |
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8815527 |
Methods and compositions for detecting the activation state of multiple proteins in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides... |
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8815320 |
Process for producing a composition containing active follistatin
A process for producing a composition containing biologically active follistatin from a biological source, which composition is preserved and, especially pathogen free and is storage stable,... |
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8808977 |
Method of inactivating virus in circular blood and its applications in treating viral diseases
The present invention relates to a method for illuminating the viruses in a circulatory blood, comprising the following steps of: 1) Adding an anticoagulant into a whole blood source and... |