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9023348 Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof  
A composition-of-matter comprising an antibody or antibody fragment including an antigen-binding region capable of specifically binding an antigen-presenting portion of a complex composed of a...
9017668 High affinity human antibodies to human cytomegalovirus (CMV) gB protein  
Antibodies to human Cytomegalovirus (CMV) gB protein have been isolated from human B cells. The affinities of these antibodies are higher than the best previously reported antibodies. Since high...
9005623 Flu virus hemagglutinin specific monoclonal antibodies  
The invention relates to a flu virus hemagglutinin-specific monoclonal antibody which recognizes an antigenic structure present both on the H1 and H3 subtypes of the hemagglutinins of type A flu...
9005621 Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof  
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses....
9005624 Binding molecules capable of neutralizing rabies virus and uses thereof  
Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules,...
8992929 Monoclonal antibody specific to major neutralizing epitope of influenza H5 hemagglutinin  
The present invention relates to the murine monoclonal antibody 4C2 or to chimeric or humanized monoclonal antibodies specific to a major neutralizing epitope of influenza H5 hemagglutinin and...
8986686 Stabilized liquid anti-RSV antibody formulations  
The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which...
8974788 Compositions and methods for the therapy and diagnosis of influenza  
The present invention provides compositions, vaccines, and methods for diagnosing, treating, and preventing influenza infection using a combination of antibodies raised against the influenza...
8961978 Human binding molecules capable of neutralizing influenza A viruses of phylogenetic group 1 and phylogenetic group 2 and influenza B viruses  
The present disclosure relates to binding molecules, such as human monoclonal antibodies, that bind to an epitope in the stem region of hemagglutinin of influenza A viruses of phylogenetic group 1...
8961977 Antigenic mimics of discontinuous epitopes of pathogen recognized by broadly neutralizing antibodies  
The present invention relates to an anti-idiotypic polypeptide scaffold that includes two or more peptide sequences that mimic a discontinuous epitope of a pathogen that is recognized by or...
8945567 Monovalent, bivalent and trivalent anti human respiratory syncytial virus (HRSV) nanobody constructs for the prevention and/or treatment of respiratory tract infections  
Amino acid sequences are provided that are directed against and/or that can specifically bind protein F of hRSV, as well as to compounds or constructs, and in particular proteins and polypeptides,...
8920804 Methods and materials for the detection of dengue virus infection  
The present invention provides monoclonal antibodies that are specific for the Dengue non-structural glycoprotein NS1 in monomeric and/or oligomeric (primarily dimeric) form, together with...
8916160 Compositions and methods for the therapy and diagnosis of influenza  
The present invention provides compositions, vaccines, and methods for diagnosing, treating, and preventing influenza infection using a combination of antibodies raised against the influenza...
8900590 Anti-hemagglutinin antibody compositions and methods of use thereof  
The present invention provides novel human anti-Influenza antibodies and related compositions and methods. These antibodies are used in the prevention, inhibition, neutralization, diagnosis, and...
8900596 Physicochemical (PCP) based consensus sequences and uses thereof  
Provided herein is a computational method for designing a PCP-consensus protein for a family of related proteins. The method uses a consensus alignment of a protein domain common to all the...
8894997 Monoclonal antibodies to influenza H1N1 virus uses thereof  
The present invention is directed to particular monoclonal antibodies and fragments thereof that find use in the detection, prevention and treatment of influenza virus infections. In particular,...
8889137 Anti-HSV antibody  
The invention relates to an anti-HSV antibody as defined in the claims, a pharmaceutical composition comprising of an effective amount of the said antibody, an expression vector comprising of a...
8883429 Viral diagnostics  
The present disclosure provides methods for determining whether a subject is infected with lymphocytic choriomeningitis virus (LCMV). These methods include obtaining a sample from a subject with...
8877187 Therapeutic antibodies for treatment and prophylaxis of transmittable viral diseases  
The invention provides methods and compositions for the treatment and prevention of a transmittable disease in a subject, such as avians and mammals. The methods and compositions of the invention...
8877200 HA binding agents  
This disclosure relates to novel peptide agents, e.g., antibodies and antigen-binding fragments thereof, that bind hemagglutinin protein of influenza viruses, and methods of their use.
8858946 Method for inhibiting HIV-1 replication utilizing anti-GBV-C E2 antibodies  
GB virus C (GBV-C or hepatitis G virus) is a flavivirus that frequently leads to chronic viremia in humans. The invention provides compositions and methods involving an anti-GBV-C antibody or...
8858948 Compositions and methods for the therapy and diagnosis of influenza  
The present invention provides novel human anti-influenza antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of influenza infection.
8852598 Puumala virus full-length M segment-based DNA vaccines  
The invention contemplates a new synthetic, codon-optimized Puumala virus (PUUV) full-length M gene open reading frame (ORF) that encodes a unique consensus amino acid sequence. The PUUV ORF was...
8852595 Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof  
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses....
8840895 Human antibodies specifically binding to the hepatitis B virus surface antigen  
Provided are antibodies specifically binding to the HBV surface antigen (HBsAg) which are effective for the prevention or treatment of hepatitis B.
8834881 Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof  
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses....
8828399 Cytomegalovirus surface protein complex for use in vaccines and as a drug target  
Immunogenic compositions and prophylactic or therapeutic vaccines for use in protecting and treating against human cytomegalovirus (CMV) are disclosed. Subunit vaccines comprising a human CMV...
8828400 Antibody that binds to H-1 parvovirus  
Described is an antibody or an antigen binding fragment thereof specifically binding to a full or empty H-1 parvovirus capsid. Such an antibody is useful for various diagnostic and therapeutic...
8795667 Compositions for the prevention and treatment of smallpox  
The present invention relates to improved compositions for the prevention and treatment of smallpox, and in particular to the use of compositions containing an antibody that binds to an epitope...
8790872 Non-elispot assay  
A method of detecting the production of an analyte by cells in a sample, which method comprises: (i) providing an antibody capable of binding to said analyte and a first agent capable of enhancing...
8784820 Plasminogen-activating antibody, use and producing method thereof and agent including the same  
An antibody for activating plasminogen is provided. The antibody is produced from a hybridoma cell line deposited on Nov. 24, 2011 under accession number BCRC 960433 at Food Industry Research and...
8784819 Influenza hemagglutinin antibodies, compositions and related methods  
Antibodies against influenza hemagglutinin, compositions containing the antibodies, and methods of using the antibodies are provided herein.
8778347 Fluorescent neutralization and adherence inhibition assays  
The present invention comprises rugged, inexpensive, reliable, and sensitive laboratory assays of antibody-based viral neutralization activity and antibody-based viral adherence inhibition...
8771698 Modulation of UL24 interactions with protein targets and uses thereof for inhibition of herpesvirus infection  
Methods and uses for the treatment of herpesvirus infection based on the inhibition of the interaction between herpesvirus UL24 and non-muscle myosin type IIa (NM2a) are described.
8765132 Human cytomegalovirus neutralizing antibodies and use thereof  
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or...
8753648 Modified poxviruses, including modified smallpox virus vaccine based on recombinant drug-sensitive vaccinia virus, and new selection methods  
The present invention provides recombinant poxviruses, such as vaccinia virus, that contain an integrated exogenous sequence, such as a foreign gene, encoding a prodrug converting polypeptide that...
8747856 Antigen binding fragments of an antibody for use in treating or diagnosing ocular diseases  
The present invention relates to the use of a fully human antigen binding fragment of an antibody for the manufacture of a medicament for the treatment or diagnosis of an ocular disease upon...
8734803 Humanized neuraminidase antibody and methods of use thereof  
Antibodies against influenza neuraminidase, compositions containing the antibodies, and methods of using the antibodies are provided herein.
8715638 Ethenyl-substituted pyridine and pyrimidine derivatives and their use in treating viral infections  
The present invention provides compounds of Formula (A): (Chemical formula should be inserted here as it appears on abstract in paper form) (A) and tautomers, isomers, and esters of said...
8691223 Human binding molecules capable of neutralizing influenza virus H5N1 and uses thereof  
Described are binding molecules such as human monoclonal antibodies that bind to influenza virus H5N1 and have neutralizing activity against influenza virus H5N1. Also described are nucleic acid...
8669047 Real-time detection of influenza virus  
The present invention provides system and methods for detecting an analyte indicative of an influenza viral infection in a sample of bodily fluid. The present invention also provides for systems...
8663950 Production of a monoclonal antibody therapeutic against west nile virus in plants  
The present invention describes the plant-based production of a therapeutic antibody against West Nile Virus.
8637035 Anti-dengue virus antibodies  
Provided herein are monoclonal antibodies specific to dengue virus as well as their antigen-binding fragments, and functional variants. Also disclosed are uses thereof for treating or diagnosing...
8637645 H5 subtype-specific binding proteins useful for H5 avian influenza diagnosis and surveillance  
The invention provides monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes of avian influenza virus (“AIV”). The monoclonal...
8623370 Vaccinia virus H3L and B5R specific monoclonal antibodies and methods of making and using same  
The invention relates to antibodies and subsequences thereof that specifically bind to poxvirus B5R envelope protein, antibodies and subsequences thereof that specifically bind to pox virus H3L...
8617808 Cultispot assay  
The invention provides a method for detecting the production of one or more analytes by cells in a sample. The method uses one or more immobilized binding proteins to capture one or more analytes...
8603480 Human cytomegalovirus neutralizing antibodies and use thereof  
The invention relates to neutralizing antibodies, and antibody fragments thereof, having high potency in neutralizing hCMV, wherein said antibodies and antibody fragments are specific for one, or...
8597651 Monomeric VHH domain derived from anti-VP6 camelid antibodies, dimeric domain, immunisation method, rotavirus detection method, composition, prevention and treatment methods for rotavirus infections  
Monomeric VHH domain derived from anti-VP6 camelid antibodies, dimeric domain, immunization method, rotavirus detection method, vaccine composition, prevention and treatment methods for rotavirus...
8586034 Cytomegalovirus disintegrin-like peptides  
The present invention relates to methods and compositions for inhibiting the entry of viruses, such as herpesviruses into a host cell. A conserved viral integrin-binding gB disintegrin-like domain...
8580256 Stabilized anti-hepatitis B (HBV) antibody formulations  
The present invention provides liquid formulations of antibodies or fragments thereof that specifically bind to a hepatitis B virus (HBV) antigen, which formulations exhibit stability, low to...

Matches 1 - 50 out of 246 1 2 3 4 5 >