|
Match
|
Document |
Document Title |
|
|
9017941 |
Microchip for analyzing nucleic acid and method of nucleic acid analysis using the same
A method for nucleic acid analysis including injecting a slight amount of nucleic acid sample for analysis, characterized in that most of a nucleic acid sample which is not used, excluding the... |
|
|
9012229 |
Capillary electrophoresis method for fine structural analysis of enoxaparin sodium
A capillary electrophoresis method for quantitatively analyzing characteristic oligosaccharide present in enoxaparin sodium is provided in this invention. The method may be used for quantitatively... |
|
|
8968540 |
Trans-base tunnel reader for sequencing
A device for reading the sequence of a polymer, consisting of a first electrode and a second electrode, each electrode being functionalized with a reader molecule strongly bonded to the... |
|
|
8961766 |
Microchannel gel electrophoretic separation systems and methods for preparing and using
A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The... |
|
|
8961765 |
Plastic microfluidic separation and detection platforms
Plastic electrophoresis separation chips are provided comprising a plurality of microfluidic channels and a detection window, where the detection window comprises a thin plastic; and the detection... |
|
|
8961764 |
Micro fluidic optic design
A DNA analyzer includes an interface for coupling a microfluidic chip to the DNA analyzer. The microfluidic chip includes a first separation channel for electrophoretic separation of DNA fragments... |
|
|
8926813 |
Devices and methods for determining the length of biopolymers and distances between probes bound thereto
Devices and methods for detecting the length of analytes, and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a fluidic channel.... |
|
|
8882980 |
Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
Devices and methods for detecting an analyte are provided. Devices for voltage sensing of analytes may comprise a fluidic channel defined in a substrate, a pair of sensing electrodes disposed in a... |
|
|
8864969 |
Electro-diffusion enhanced bio-molecule charge detection using electrostatic interaction
According to one aspect, the disclosure is directed to an example embodiment in which a circuit-based arrangement includes a circuit-based substrate securing a channel, with an effective width... |
|
|
8858770 |
Plastic microfluidic separation and detection platforms
Plastic electrophoresis separation chips are provided comprising a plurality of microfluidic channels and a detection window, where the detection window comprises a thin plastic; and the detection... |
|
|
8834694 |
Dry compositions and methods for gel electrophoresis
The invention provides dry compositions for preparing and loading a sample on a gel for electrophoretic separation. The dry compositions preferably include a tracking dye and a sedimenting agent... |
|
|
8834696 |
Amplified electrokinetic fluid pumping switching and desalting
The present invention provides a device and methods of use thereof for desalting a solution. The methods, inter-alia, make use of a device comprising microchannels, which are linked to conduits,... |
|
|
8784626 |
Bio-analysis using ball-ended incident and output optical fibers
A detection optics configuration for bio-analysis, in which the direction of incident radiation, the axis of the separation channel, and the direction of collection of the output radiation are... |
|
|
8778155 |
Disposible bio-analysis cartridge and instrument for conducting bio-analysis using same
A cartridge-based bio-separation system configured to utilize a pen shaped bio-separation cartridge that is easy to assemble and use with no moving parts and that has an integrated reagent... |
|
|
8771491 |
Ultrafast sequencing of biological polymers using a labeled nanopore
Methods and systems for sequencing a biological molecule or polymer, e.g., a nucleic acid, are provided. One or more donor labels, which are attached to a pore or nanopore, may be illuminated or... |
|
|
8721859 |
Analysis apparatus and analysis method
An analysis apparatus is an apparatus that performs electrophoresis using a microchip provided with a channel. The analysis apparatus includes a cooling unit (an electron cooling element and a... |
|
|
8663990 |
Measurement method utilizing internal standard substance
A subject of the present invention is to provide a measurement method using an internal standard substance in an electrophoresis where an analyte is a protein or a compound. The present invention... |
|
|
8628649 |
Nanopore and carbon nanotube based DNA sequencer and a serial recognition sequencer
The present invention is directed to systems, devices and methods for identifying biopolymers, such as strands of DNA, as they pass through a constriction such as a carbon nanotube nanopore. More... |
|
|
8597485 |
Optical detection alignment coupling apparatus
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical... |
|
|
8524060 |
Microchannel gel electrophoretic separation systems and methods for preparing and using
A micro-analytical platform for performing electrophoresis-based immunoassays was developed by integrating photopolymerized cross-linked polyacrylamide gels within a microfluidic device. The... |
|
|
8486247 |
Use of microfluidic systems in the electrochemical detection of target analytes
The invention relates generally to methods and apparatus for conducting analyses, particularly microfluidic devices for the detection of target analytes. |
|
|
8475640 |
Method for multiplexed capillary electrophoresis signal cross-talk correction
The present invention provides a simple method to correct cross-talk, after the data have been generated. Adjacent signals are simply subtracted from the original observed signal with a repeating... |
|
|
8465637 |
Ion sensor for fluid and method for its manufacture
The invention provides a method for the measurement of a concentration of a charged species in a sample, the sample having a plurality of types of charged species and at least one insoluble... |
|
|
8449880 |
Chemical modification of proteins for their more accurate molecular-weight determination by electrophoresis
Disclosed herein is a composition and method for sample preparation of proteins for their size separation by electrophoresis, suitable for molecular-weight determination of proteins in the range... |
|
|
8357277 |
Enhanced method for detecting and/or quantifying an analyte in a sample
The invention relates to an enhanced method of detecting and/or quantifying at least one analyte in a sample. |
|
|
8277659 |
Microchip capillary electrophoresis absent electrokinetic injection
Microchip capillary electrophoresis (CE) utilizing a sample injector based on a mechanical valve rather than electrokinetic injection can provide improved sample injections, enhanced capabilities,... |
|
|
8268249 |
Analytical device with lightguide illumination of capillary and microgroove arrays
An analytical cell including a lightguide with a plurality of conduits filled with a migration medium. The medium, the lightguide and a surrounding medium have refractive indices selected such... |
|
|
8246803 |
Capillary electrophoresis apparatus and electrophoresis method
An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal... |
|
|
8246799 |
Devices and methods for analyzing biomolecules and probes bound thereto
Devices and methods for detecting the length of analytes and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a nanopore or fluidic... |
|
|
8246806 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than... |
|
|
8206568 |
Material deposition techniques for control of solid state aperture surface properties
The invention provides a method for molecular analysis. In the method, sidewalls are formed extending through a structure between two structure surfaces, to define an aperture. A layer of material... |
|
|
8182746 |
Electrophoresis process using a valve system
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus... |
|
|
8173417 |
Ruggedized apparatus for analysis of nucleic acid and proteins
The invention provides methods and systems for ruggedizing a nucleic acid analyzing apparatus. The ruggedized apparatus can be used reliably and effectively in uncontrolled environments, such as,... |
|
|
8163151 |
Assays for detection of Von Willebrand factor (vWF) multimers and for degradation of vWF by agents such as Adamts13 and related methods
Methods of analyzing the electrophoretic mobility distribution of von Willebrand factor (vWF) multimers include providing a sample medium comprising a plurality vWF multimers. The vWF multimers... |
|
|
8118986 |
Determination of the hydrodynamic radii of the constituents of an admixture by means of analysis of a taylor dispersion carried out following a separation by means of capillary electrophoresis
A method for determining the hydrodynamic radius for the constituents of an admixture, includes: (A) by separating capillary electrophoresis, the constituents of the admixture, leaving them within... |
|
|
8052856 |
Support for capillaries, case for constraining capillaries including the same
A support for capillaries comprises a ceramic member having a flat surface area on which the capillaries are to be aligned. The flat surface area has a flatness of not more than 0.02 mm and has a... |
|
|
8043493 |
Multi-capillary array electrophoresis device
An electrophoresis apparatus includes a multi-capillary array having a liquid or solid disposed between the capillaries of the array. The liquid or solid exhibits a refractive index higher than... |
|
|
8030092 |
Controlled electrophoresis method
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus... |
|
|
8012327 |
Capillary electrophoresis apparatus and electrophoresis method
An object of the present invention is to provide a capillary electrophoresis apparatus in which simultaneity can be ensured between sensitivity and data acquisition to decrease a pull-up signal... |
|
|
8007725 |
Electrophoresis apparatus having valve system
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus... |
|
|
7943027 |
Electrophoresis unit and electrophoretic analysis method
The object of the present invention is that a dynamic range is extended in an electrophoresis unit and concentration differences among a plurality of samples measured simultaneously are increased.... |
|
|
7901557 |
Method for multiplexed capillary electrophoresis signal cross-talk correction
The present invention provides a simple method to correct cross-talk, after the data have been generated. Adjacent signals are simply subtracted from the original observed signal with a repeating... |
|
|
7837848 |
Bidimensional separation by means of capillary electrophoresis carried out in a single capillary
A method for separating the constituents of a mixture M by electrophoresis in a single capillary includes (A) separating compounds of the mixture M in a single capillary according to the capillary... |
|
|
7780831 |
Assays for detection of von willebrand factor (vWF) multimers and for degradation of vWF by agents such as ADAMTS13 and related methods
Methods of analyzing the electrophoretic mobility distribution of von Willebrand factor (vWF) multimers include providing a sample medium comprising a plurality vWF multimers. The vWF multimers... |
|
|
7758737 |
Total analyte quantitation
Methods for determining total analyte concentrations and amounts, especially in combination with analyte separations are provided. Microfluidic devices are used to separate analyte mixtures and... |
|
|
7736482 |
Electrophoresis member, production thereof and capillary electrophoresis apparatus
An electrophoresis member is produced by laying a plurality of capillaries on an adhesive layer born on a support layer to form a capillary layer, laminating thereon a second support layer, and... |
|
|
7713394 |
Electrophoresis apparatus using capillary array and sample plate assembly used therefor
A sample plate assembly for an electrophoresis apparatus including a tray at a sample supply portion of a capillary array, an adapter for the tray, a sample plate mounted on the adapter, a septer... |
|
|
7691247 |
Optical detection alignment coupling apparatus
An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical... |
|
|
7670471 |
Method and apparatus for analysis and sorting of polynucleotides based on size
The invention relates to a microfabricated device and methods of using the device for analyzing and sorting polynucleotide molecules by size. |
|
|
7655129 |
Binding acceleration techniques for the detection of analytes
The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron... |