Matches 1 - 31 out of 31


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US20110162094 MODIFIED HUMAN FACTOR VII/VIIA AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME  
Modified factors VII/VIIa with a high stability, nucleic acids encoding such modified factors VII/VIIa, and methods of preparing the same.
US20130131317 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20120259093 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20110077208 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20110209229 Gene of porcine beta casein, a promoter of the same and the use thereof  
The present invention provides a porcine beta-casein gene, a porcine beta-casein gene promoter, an expression vector comprising the same promoter, and a method for the production of a target...
US20130053546 Use of Anticoagulants in the Production of Recombinant Proteins in the Milk of Transgenic Animals  
The invention relates to the production of recombinant human fibrinogen (rhFib) in the milk of transgenic mammalian animals. This production and subsequent purification process is generally...
US20100125918 ENTEROVIRUS TYPE 71 PROTEIN AND METHOD FOR PRODUCTION  
The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus....
US20100024047 Prion-free transgenic ungulates  
Transgenic and cloned ungulates and particularly cloned cattle are disclosed, wherein such cattle contain a deletion or disruption of the prion gene locus and do not express functional prion...
US20110239314 Gene of porcine alpha-si casein, a promoter of the same and use thereof  
The present invention relates to a porcine alpha-S1-casein gene, a porcine alpha-S1-casein gene promoter, an expression comprising the same promoter, and a method for the production of a target...
US20060130159 Method of purifying recombinant MSP 1-42 derived from Plasmodium falciparum  
Methods of purifying MSP-1 from a variety of source materials including from the milk of transgenic mammals.
US20080026072 Antimicrobial Carbohydrates and Methods of Using Same  
Compositions useful for inhibiting the growth of bacteria, including bacteria that can cause gastric ulcers, are provided. In addition, transgenic organism that can produce such compositions are...
US20110067122 Expression of Xenogenous (Human) Immunoglobulins in cloned, transgenic ungulates  
The present invention relates to the production of a transgenic ungulate which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies,...
US20110072526 PROCESS FOR PRODUCING EXOGENOUS PROTEIN IN THE MILK OF TRANSGENIC MAMMALS AND A PROCESS FOR PURIFYING PROTEINS THEREFROM  
The invention relates to a method of producing a protein of interest, comprising making a non-human transgenic mammal that produces said protein in its milk, obtaining said milk from the non-human...
US20050193432 Xenograft model of functional normal and malignant human breast tissues in rodents and methods thereof  
The invention relates to an orthotopic xenograft rodent model in which the stromal and epithelial components of the reconstructed mammary gland are of human origin, and to methods of making the...
US20100162418 RECOMBINANT PROTEIN S COMPOSITION  
A pharmaceutical agent for treating a disease such as inflammatory diseases, blood coagulation diseases associated with deficiency of Protein S has been required. The present invention provides a...
US20100293623 Rabbit nuclear cloning method and uses thereof  
The invention concerns a method for producing non-human mammal embryos, in particular rabbit by nuclear cloning. The invention also concerns the mammals obtained and their uses.
US20060130158 Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains  
Fusion proteins of transferrin and other therapeutic moieties with increased serum half-life or serum stability are disclosed. Preferred fusion proteins include those modified so that the...
US20100205680 MAMMARY GLAND- SPECIFIC HUMAN ERYTHEROPOIETIN EXPRESSION VECTOR, TRANSGENIC ANIMAL AND METHOD FOR PRODUCING HUMAN ERYTHROPOIETIN USING SAME  
The present invention provides a mammary gland-specific human erythropoietin expression (hEPO) vector, transgenic animal and method for producing human erythropoietin using the same. The inventive...
US20060191026 Tissue specific expression of antibodies in chickens  
Transgenes encoding exogenous antibodies are stably integrated into donor cells and are present in the somatic tissue of chimeric birds. The transgenes encode exogenous antibodies and are...
US20090013419 CATTLE BETA-CASEIN GENE TARGETING VECTOR USING HOMOLOGOUS RECOMBINATION  
The present invention relates to a bovine beta-casein gene targeting vector comprising (1) a first region having a length of 5 to 12 kb which is homologous to the promoter and its flanking nucleic...
US20060272036 Ruminant mhc class-i-like fc receptors  
Immunoglobulin G (IgG) transporting ruminant Fc receptor (FcRn) α-chain DNA molecules, especially those of cow, dromedary and sheep (SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3) are disclosed. Protein...
US20070118912 BOVINE ABCG2 GENE MISSENSE MUTATIONS AND USES THEREOF  
A quantitative trait locus (QTL) affecting milk fat and protein concentration was localized to a 4cM confidence interval on chromosome 6 centered on the microsatellite BM143. The genes and...
US20070056050 PRODUCTION OF BONE MORPHOGENIC PROTEINS (BMPs) IN TRANSGENIC MAMMALS  
The present invention provides materials and methods for the production of recombinant BMPs in transgenic animals. In particular, the invention provides materials and methods for the production of...
US20080063780 Methods and products related to the transfer of molecules from blood to the mammary gland  
The invention provides, in part, methods for the production of proteins in a transgenic non-human mammal, wherein the proteins are transported from the blood to the mammary gland for secretion in...
US20080118501 Antibodies with enhanced antibody-dependent cellular cytotoxicity activity, methods of their production and use  
The invention relates, in part, to antibodies with increased ADCC activity. Methods of producing such antibodies are also provided. The antibodies of the invention are produced in mammary...
US20050097625 Modified antibodies stably produced in milk and methods of producing same  
The invention features methods of producing an antibody in the milk of a transgenic mammal. The methods include providing a transgenic mammal whose somatic and germ cells comprise a sequence...
US20060185029 Avians that produce eggs containing exogenous proteins  
This invention provides for proteins which are expressed in the avian oviduct, packaged into eggs laid by the avian.
US20050193431 Somatic cell line  
The invention features a purified embryonic or fetal caprine somatic cell. The somatic cell can be in a preparation of embryonic or fetal caprine somatic cells. In addition, the cell can be used...
US20080220002 MODIFIED TRANSFERIN-ANTIBODY FUSION PROTEINS  
Modified fission proteins of transferrin and therapeutic proteins or peptides, preferably antibody variable regions, with increased serum half-life or serum stability are disclosed. Preferred...
US20160177286 GLA-DOMAINLESS FACTOR X  
The present invention relates to a protein consisting of the sequence SEQ ID No.: 11 or 25 or 26, directly bound, or bound via a linker, especially -Arg-Lys-Arg-, to the sequence SEQ ID No.: 6.
US20150374801 PROTEINS WITH MODIFIED GLYCOSYLATION AND METHODS OF PRODUCTION THEREOF  
In one aspect, the disclosure provides proteins with modified glycosylation and methods of their production. In aspect, the disclosure provides transgenic animals and cells for the production of...

Matches 1 - 31 out of 31