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US20100333218 TRANSGENIC PROTEINS FROM MULTI-GENE SYSTEMS, METHODS, COMPOSITIONS, USES AND THE LIKE RELATING THERETO  
A non-human transgenic mammalian animal, as described above, contains one or more exogenous double stranded DNA sequence(s) stably integrated into the genome of the animal, which comprises...
US20150067899 Multiple Inducible Gene Regulation System  
The present invention relates to the field of biotechnology or genetic engineering. More specifically, the present invention relates to a multiple inducible gene regulation system that functions...
US20110023141 GENOMIC EDITING OF GENES INVOLVED WITH PARKINSON'S DISEASE  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with Parkinson's disease. In particular, the animals or...
US20110023158 BOVINE GENOME EDITING WITH ZINC FINGER NUCLEASES  
The present invention provides a genetically modified bovine or cell comprising at least one edited chromosomal sequence. In particular, the chromosomal sequence is edited using a zinc finger...
US20110283375 Transgenic Prothrombin And Related Thrombin Precursors And Transgenics, Methods, Compositions, Uses And The Like Relating Thereto  
The invention provides, among other things, activatable prothrombin, compositions comprising prothrombin, transgenic organisms for making prothrombin, methods for making the transgenic organisms,...
US20110023139 GENOMIC EDITING OF GENES INVOLVED IN CARDIOVASCULAR DISEASE  
The present invention provides genetically modified animals and cells comprising edited chromosomal involved in cardiovascular disease. In particular, the animals or cells are generated using a...
US20110023151 GENOME EDITING OF ABC TRANSPORTERS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding ABC transporter proteins. In particular, the animals or cells are generated...
US20140201857 HORNLESS LIVESTOCK  
Compositions and methods for making livestock with a polled allele are presented, including migrating a polled allele into a bovine species without changing other genes or chromosomal portions.
US20110016543 GENOMIC EDITING OF GENES INVOLVED IN INFLAMMATION  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding inflammation-related proteins. In particular, the animals or cells are...
US20110126297 TRANSGENIC ANIMAL WITH MONOCYTE CHEMOTACTIC PROTEIN 1 PROMOTER  
The present invention relates to a transgenic animal, which comprises in its genome a recombinant polynucleotide encoding one or more reporter proteins and a monocyte chemotactic protein-1 (MCP-1)...
US20110023146 GENOMIC EDITING OF GENES INVOLVED IN SECRETASE-ASSOCIATED DISORDERS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with a secretase disorder. In particular, the...
US20130219533 PLA2G16 AS A TARGET FOR ANTIVIRAL COMPOUNDS  
In some aspects, the invention provides compositions and methods for inhibiting viral infection. In some aspects, the invention provides compositions and methods useful for identifying antiviral...
US20150150153 ARTIFICIAL OOCYTE ACTIVATION  
The present invention provides novel methods for improving the efficiency of artificial activation of unfertilized mammalian oocytes by reducing the intracellular concentration of Zn2+ in the...
US20140182005 SPERM CELL SEPARATION METHODS AND COMPOSITIONS CONTAINING SPERM CELL TARGETING LIGANDS FOR USE THEREIN  
The present invention provides sperm cell targeting ligands, including DNA-binding proteins, that bind target molecules on the surface of, accessible from the surface of, or inside mammalian sperm...
US20110023145 GENOMIC EDITING OF GENES INVOLVED IN AUTISM SPECTRUM DISORDERS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with ASD. In particular, the animals or cells are...
US20110023153 GENOMIC EDITING OF GENES INVOLVED IN ALZHEIMER'S DISEASE  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with AD. In particular, the animals or cells are...
US20120167239 Novel ecdysone receptor/invertebrate retinoid X receptor-based inducible gene expression system  
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to a...
US20110016540 GENOME EDITING OF GENES ASSOCIATED WITH TRINUCLEOTIDE REPEAT EXPANSION DISORDERS IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with trinucleotide repeat expansion disorders....
US20120023599 GENOME EDITING OF CYTOCHROME P450 IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding cytochrome P450 (CYP) proteins. In particular, the animals or cells are...
US20110023148 GENOME EDITING OF ADDICTION-RELATED GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with addiction disorders. In particular, the animals or...
US20140123330 CONTROL OF SEXUAL MATURATION IN ANIMALS  
A genetically modified livestock animal comprising a genome that comprises inactivation of a neuroendocrine gene selective for sexual maturation, with the inactivation of the gene preventing the...
US20100077491 Modulators of RNF5 and Uses Thereof  
Provided herein are compositions and methods relating to the involvement of RNF5 in muscle wasting.
US20120128682 APOLIPOPROTEIN L- I VARIANTS AND THEIR USE  
An isolated human Apolipoprotein L-I corresponding to a wild type human Apolipoprotein sequence is modified by a deletion at its C-terminal end.
US20120159653 GENOMIC EDITING OF GENES INVOLVED IN MACULAR DEGENERATION  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins associated with MD. In particular, the animals or cells are...
US20090133133 Transgenic Mice for Bioassay of Prions from Deer and Elk with Chronic Wasting Disease  
The invention relates to the use of transgenic constructs to produce animal models for the study of chronic wasting disease.
US20130031648 Use of Follistatin-Like Related Gene (FLRG) to Increase Muscle Mass  
The present relates to use of follistatin-like related gene (FLRG) to increase muscle mass in a subject. As such, methods of ameliorating the severity of a pathologic condition characterized, at...
US20080115234 Method for utilization of domestic ruminants with mycobacterium avium subspecies paratuberculosis disease to assess possible therapeutic modalities  
The invention describes a concrete schema which allow domesticated ruminant with disease due to Mycobacterium avium subspecies paratuberculosis to serve as an animal model system in order to...
US20110023147 GENOMIC EDITING OF PRION DISORDER-RELATED GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with cognitive disorders. In particular, the...
US20130131317 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20120259093 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20110077208 EXPRESSION OF SECRETED HUMAN ALPHA-FETOPROTEIN IN TRANSGENIC ANIMALS  
The invention features a process of expressing secreted recombinant human alpha-fetoprotein (rHuAFP) in the milk or urine of transgenic mammals.
US20110209229 Gene of porcine beta casein, a promoter of the same and the use thereof  
The present invention provides a porcine beta-casein gene, a porcine beta-casein gene promoter, an expression vector comprising the same promoter, and a method for the production of a target...
US20110016539 GENOME EDITING OF NEUROTRANSMISSION-RELATED GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with neurotransmission disorders. In particular,...
US20120185954 Mutant Receptors and Their Use in a Nuclear Receptor-Based Inducible Gene Expression  
This invention relates to the field of biotechnology or genetic engineering. Specifically, this invention relates to the field of gene expression. More specifically, this invention relates to...
US20110030072 GENOME EDITING OF IMMUNODEFICIENCY GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding immunodeficiency proteins. In particular, the animals or cells are generated...
US20110016541 GENOME EDITING OF SENSORY-RELATED GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with nociception or taste disorders. In...
US20110023143 GENOMIC EDITING OF NEURODEVELOPMENTAL GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with neurodevelopmental disorders. In...
US20050177883 Systems of transferring embryos and managing recipients  
Provided herein are methods of managing embryo transfer programs, for instance bovine embryo transfer programs. Examples of such methods are referred to as “bred recipient transfer” programs, in...
US20100125918 ENTEROVIRUS TYPE 71 PROTEIN AND METHOD FOR PRODUCTION  
The invention provides a new type of a capsid protein VP1 of human enterovirus 71, named as MEL701-VP1 and functional/structural variants thereof, which is used for protection against enterovirus....
US20110023152 GENOME EDITING OF COGNITION RELATED GENES IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences encoding proteins that are associated with cognitive disorders. In particular, the...
US20080051328 Novel Muscle Growth Regulator  
A muscle growth regulating factor includes polynucleotide and polypeptide sequences, promoter sequences, constructs comprising the sequences, and compositions for regulating muscle growth and...
US20100024047 Prion-free transgenic ungulates  
Transgenic and cloned ungulates and particularly cloned cattle are disclosed, wherein such cattle contain a deletion or disruption of the prion gene locus and do not express functional prion...
US20120159654 GENOME EDITING OF GENES INVOLVED IN ADME AND TOXICOLOGY IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences involved in ADME and toxicology. In particular, the animals or cells are generated...
US20110023150 GENOME EDITING OF GENES ASSOCIATED WITH SCHIZOPHRENIA IN ANIMALS  
The present invention provides genetically modified animals and cells comprising edited chromosomal sequences associated with schizophrenia. In particular, the animals or cells are generated using...
US20110231943 TRANSGENIC ANIMALS AND USES THEREOF  
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic...
US20110239314 Gene of porcine alpha-si casein, a promoter of the same and use thereof  
The present invention relates to a porcine alpha-S1-casein gene, a porcine alpha-S1-casein gene promoter, an expression comprising the same promoter, and a method for the production of a target...
US20120233715 HUMAN ARTIFICIAL CHROMOSOME VECTOR  
A human artificial chromosome vector comprising a human antibody heavy chain gene, a human antibody light chain gene, and a human antibody surrogate light chain gene.
US20120222143 GENETICALLY MODIFIED ANIMALS AND METHODS FOR MAKING THE SAME  
Compositions and methods for use of TALENs to make genetically modified livestock are set forth. The methods may include reporters for selecting cells or embryos that have been modified by TALENs...
US20110093965 PHOSPHOLIPASES, NUCLEIC ACIDS ENCODING THEM AND METHODS FOR MAKING AND USING THEM  
The invention provides novel polypeptides having phospholipase activity, including, e.g., phospholipase A, B, C and D activity, patatin activity, phosphatidic acid phosphatases (PAP) and/or lipid...
US20050155093 Rabbit nuclear cloning method and uses thereof  
The invention concerns a method for producing non-human mammal embryos, in particular rabbit by nuclear cloning. The invention also concerns the mammals obtained and their uses.

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