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US20110137329 NERVE REGENERATION EMPLOYING KERATIN BIOMATERIALS  
A keratin hydrogel matrix serves as an effective acellular scaffold for axonal regeneration and facilitates functional nerve recovery.
US20110082482 Materials and Methods for Nerve Repair  
The subject invention pertains to compositions and methods for promoting repair of damaged nerve tissue. The compositions and methods of the subject invention can be employed to restore the...
US20120253423 Artificial Nerve Networking System and Method for Functional Recovery of Damaged Nerve  
Disclosed are a system and a method for artificial nerve networking capable of restoring a damaged nerve and allowing selective detection, analysis, transmission and stimulation of a signal from...
US20130171116 OPTICALLY SENSITIVE CELL NETWORK  
A neural network is disclosed. The neural network comprises a plurality of optogenetically modified neural cells being three-dimensionally distributed in a hydrogel medium and being disconnected...
US20120053580 METHOD AND SYSTEM FOR NERVE REPAIR, NANOKNIFE, MEMS PLATFORM AND USES THEREOF  
Method and systems for nerve repair and for microfabrication. In specific embodiments, nerve repair is accomplished by repairing axons. In further embodiments, a modular, 3D system having very...
US20120065740 Method for connecting nerves via a side-to-side epineurial window using artificial conduits  
The disclosure provides methods for repairing nerves and inhibiting atrophy of a muscle via a side-to side neurorraphy using a bridging element between a first epineurial window on a donor nerve...
US20110152898 TISSUE ENGINEERED CONSTRUCTS  
The present invention relates to a field of biocompatible membranes, tubes and conduits which comprising a photosensitizer which is capable of being crosslinked to form a three dimensional...
US20110137328 Nerve Repair with a Hydrogel and Optional Adhesive  
The subject invention provides materials and methods for effective nerve repair. In a preferred embodiment, the subject invention provides nerve repair methods comprising the use of a fibrin glue...
US20110276066 Multichannel collagen nerve conduit for nerve repair  
The present invention relates to the fabrication of multichannel nerve conduits for use in the repair of nerve injury. In particular, the invention relates to collagen multichannel nerve conduits...
US20090024150 NERVE GUIDE  
The aim of the invention is to provide a nerve guide that allows the axons to develop fairly freely during regeneration. For this purpose, the nerve guide is produced based on a shaped body from a...
US20110245852 MEDICAL DEVICE  
The present invention provides a peripheral nerve growth conduit for peripheral nerve repair, in particular conduits through which peripheral nerves can grow. The conduit includes...
US20140336681 METHODS AND DEVICES FOR CONNECTING NERVES  
A nerve repair conduit configured to be secured on first and second portions of a selected nerve. The nerve repair conduit includes a polymeric body having a proximal end, a distal end, an...
US20110129515 Devices and Methods for Nerve Regeneration  
The present invention is directed to a nerve regeneration conduit including a resorbable tube having a matrix therein. The matrix is characterized by substantially parallel, axially aligned pores...
US20120150205 SILK NANOFIBER NERVE CONDUIT AND METHOD FOR PRODUCING THEREOF  
The present invention relates to a silk nanofiber nerve conduit characterized in that fibroin nanofibers having a diameter of 200 to 400 nm, originated from silk fiber, are stacked layer upon...
US20140163587 NERVE GUIDE CONDUIT  
A nerve guide conduit comprising a first open cover, a second open cover and a connecting portion is provided. The first open cover has a first guiding recess, a first terminal surface and a...
US20140081297 BIODEGRADABLE NERVE GUIDES  
The present invention is directed to the compositions and methods of preparing hydrogel-grafted nerve guides for peripheral nerve regeneration. Particularly, the present invention describes the...
US20110066169 METHODS FOR TREATING AN INJURED NERVE PATHWAY  
Methods and apparatus are provided for treating an injured or severed nerve pathway, wherein one or more microporous tubes are implanted into the nerve pathway to bridge the injured or severed...
US20110125170 HYDROGEL-GRAFTED DEGRADABLE NERVE GUIDES  
The present invention is directed to the compositions and methods of preparing hydrogel-grafted nerve guides for peripheral nerve regeneration. Particularly, the present invention describes the...
US20130018454 Small Diameter Vascular Graft Produced by a Hybrid Method  
The present invention relates to a hybrid graft and methods of generating the hybrid graft. The hybrid graft comprises an exterior surface and a luminal surface. The luminal surface comprises a...
US20150032137 DESIGN OF A CONDUIT FOR PERIPHERAL NERVE REPLACEMENT  
A biphasic material and devices comprising the same are provided for the development of conductive conduits that may be used for the treatment of peripheral nerve injury. These devices or conduits...
US20130060266 NEURAL PROSTHESIS AND METHOD FOR PRODUCING A NEURAL PROSTHESIS  
The invention relates to a neural prosthesis, a neural prosthesis for use in the treatment of severed nerves and to a method for producing a neural prosthesis. Said neural prosthesis comprises a...
US20140277001 SYSTEM FOR PROVIDING FLUID FLOW TO NERVE TISSUES  
Provided is an apparatus that includes a nerve conduit and a nested manifold for providing a reduced pressure. Also provided is a system that includes a source of reduced pressure, a nerve conduit...
US20130110138 THREE-DIMENSIONAL SCAFFOLDS, METHODS FOR FABRICATING THE SAME, AND METHODS OF TREATING A PERIPHERAL NERVE OR SPINAL CORD INJURY  
One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction...
US20120221025 ELECTROSPUN NERVE GUIDES FOR NERVE REGENERATION DESIGNED TO MODULATE NERVE ARCHITECTURE  
Nerve guides which are formed from three dimensional (3D) arrays of highly aligned electrospun fibers are provided. The electrospun fibers are oriented parallel to the long axis of the guide, and...
US20140107590 NERVE COAPTATION APPARATUS  
An apparatus for coaptation of first and second severed nerve segments. The apparatus includes a plurality of nerve-engaging features or coupling members that each connect to another coupling...
US20120203254 Allogenic Vessel Nerve Conduit  
The present invention relates to a method for repairing a peripheral nerve injury. The method comprises providing an immunologically inactive allogenic vessel at a peripheral nerve injury site and...
US20130331869 Conductive polymeric composites of polycaprolactone fumarate and polypyrrole for nerve regeneration  
A novel electrically conductive polymer composite composed of polycaprolactone fumarate-polypyrrole (PCLF-PPy) for applications in nerve regeneration is disclosed. The synthesis and...
US20130184724 MEDICAL DEVICE  
The present invention provides a peripheral nerve growth scaffold including poly ε-caprolactone (PCL) and microgrooves on an inner surface of the scaffold, the scaffold being adapted for use in...
US20110288569 NERVE REGENERATION-INDUCING TUBE  
The present invention provides a nerve regeneration-inducing tube in which collagen having excellent adhesive property, cell growth property and differentiation inducing property to nerve cells is...
US20130345729 COMPRESSION AND KINK RESISTANT IMPLANTS  
A compression and kink resistant tubular implant for nerve repair. The implant includes a tubular biopolymeric membrane and a polymeric supporting filament. Also provided is a shaped compression...
US20120109167 NERVE GUIDE CONDUIT CONTAINING CARBON NANOTUBES  
The embodiments herein relate to a conduit comprising an insulating material in a form of a tube having an inner surface and an outer surface, the inner surface having carbon nanotubes.
US20060184185 Device for promoting regeneration of an injured nerve, a kit and a biodegrade sheet for preparing such a device  
The invention relates to promotion of a process for regeneration of an injured nerve using a plurality of guiding means, preferably a plurality of guiding fibres, presenting an in vivo...
US20100023031 NEURAL GUIDE  
A neural guide (1) apt to receive a pair of nerve stumps (N1, N2) to allow nerve regeneration therethrough, comprising a first (2) and a second half-shell member (3) closeable the one on the other...
US20140100591 METHOD FOR THE MANUFACTURE OF NERVE REGENERATION-INDUCING TUBE  
A method for manufacturing a nerve regeneration-inducing tube with excellent pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance, resistance to invasion...
US20070168044 Self-aligning tissue growth guide  
The present invention relates to artificial tissue growth guides comprising a core and an outer sleeve, which facilitates the regeneration of damaged tissues, such as nerves. The core is fixed to...
US20070250114 Flexible tissue sheath for fibrous connective tissue repair  
A flexible tissue sheath for treating a lacerated fibrous connective tissue is disclosed and can include a hollow body that can define an interior surface and an exterior surface. At least one...
US20060085063 Nano- and micro-scale engineering of polymeric scaffolds for vascular tissue engineering  
In one aspect, the invention relates to a synthetic conduit comprising a substantially tubular body comprising substantially circumferential polymer fibers; wherein the body has an exterior...
US20100057116 POROUS MATERIAL CONDUIT AND METHOD FOR PREPARING THE SAME  
The present invention provides a porous material conduit and a method for preparing the same, wherein the porous material conduit includes a porous material basal body and one or more...
US20070156158 Device for treating carpal tunnel syndrome  
A device for treating a patient having carpal tunnel disease includes a neural stent formed from an elastically deformable material or one that has shape memory properties. The neural stent is in...
US20130190786 NEURAL IMPLANT  
A neural implant comprising spider silk, especially a neural implant consisting of natural spider silk fibres. In particular, the present invention makes available spider silk for use for the...
US20060287660 Electrically Stimulating Nerve Regeneration  
This document pertains generally to the field of nerve regeneration and more particularly to functional recovery after nerve injury or transection. For example, this document provides a silicon...
US20100268336 Materials and Method for Promotion of Nerve Regeneration  
The subject invention pertains to the therapeutic use of certain GAG-degrading enzymes, and enzyme combinations, to promote nerve repair and regeneration.
US20140379009 IMPLANTABLE NERVE CONDUIT HAVING A POLYMER FIBER SPIRAL GUIDANCE CHANNEL  
A nerve guidance conduit includes a spiral structured porous sheet decorated with channels on its surface and electrospun nanofibers in a parallel alignment with the channels and an outer tubular...
US20100234863 NANOFIBROUS CONDUITS FOR NERVE REGENERATION  
A hollow fibrous conduit for promoting regeneration of a severed nerve, comprising a first end for coapting the conduit to a first end of a severed nerve and second end for coapting the conduit to...
US20070100358 A Biomimetic Synthetic Nerve Implant  
A biomimetic biosynthetic nerve implant (BNI) that uses a hydrogel-based, transparent, multi-channel matrix as a 3-D substrate for nerve repair is disclosed. Novel scaffold-casting devices were...
US20100076465 FIBRIN-BASED NERVE REPAIR CONDUIT AND METHOD OF PRODUCING THE SAME  
A bioresorbable fibrin-based nerve repair conduit produced from tissue glue is disclosed. The nerve repair conduit may be in the form of a sheet or a tube, and may additionally comprise a serine...
US20100094318 METHODS OF MAKING COLLAGEN FIBER MEDICAL CONSTRUCTS AND RELATED MEDICAL CONSTRUCTS, INCLUDING NERVE GUIDES AND PATCHES  
The disclosure describes methods of winding collagen fiber to make medical constructs and related collagen fiber tube and patch devices.
US20070118156 Bioartificial guidance conduit and method for forming the same  
The present invention discloses a bioartificial guidance conduit formed by coaxially stacking a plurality of discs and the method for forming the same, wherein each disc contains at least one...
US20090099580 METHODS AND APPARATUS FOR ENHANCED GROWTH OF PERIPHERAL NERVES AND NERVOUS TISSUE  
A medical device comprises a tubular body having a lumen and a long axis; and a plurality of silk elements laid substantially parallel along the long axis of the lumen of the tubular body. A...
US20100249811 METHOD FOR THE MANUFACTURE OF NERVE REGENERATION-INDUCING TUBE  
To provide a method for the manufacture of a nerve regeneration-inducing tube being excellent in pressure resistance, shape recovery property, anti-kink property, film exfoliation resistance,...

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