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US20100016783 NON-INVASIVE SYSTEMS AND METHODS FOR IN-SITU PHOTOBIOMODULATION  
Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases...
US20160310395 METHODS FOR GENERATING NEW HAIR FOLLICLES, TREATING BALDNESS, AND HAIR REMOVAL  
The present invention provides methods of treating baldness in a subject and generating new hair follicles, comprising epidermal disruption and administration of a compound that promotes a...
US20140114233 METHODS AND SYSTEMS FOR TOXIN DELIVERY TO THE NASAL CAVITY  
Methods and systems for delivering toxin and toxin fragments to a patient's nasal cavity provide for both release of the toxin and delivery of energy which selectively porates target cells to...
US20120330147 Therapeutic Inflatable Devices, Systems, and Methods for Multiple Sclerosis, Deep Vein Thrombosis, and Pulmonary Embolism  
Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis, Deep Vein Thrombosis, and/or Pulmonary...
US20120238946 ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME  
Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more...
US20120238940 CYCLOOXYGENASE INHIBITOR AND CALCIUM CHANNEL ANTAGONIST COMPOSITIONS AND METHODS FOR USE IN UROLOGICAL PROCEDURES  
Compositions of a cyclooxygenase inhibitor and a calcium channel antagonist in a liquid carrier. The composition may be administered the urinary tract during urological diagnostic, interventional,...
US20120232465 ULTRASOUND CATHETER AND METHODS FOR MAKING AND USING SAME  
Ultrasound catheter devices and methods provide enhanced disruption of blood vessel obstructions. Generally, ultrasound catheters include an elongate flexible catheter body with one or more...
US20120165668 Systems and methods for treating acute and/or chronic injuries in soft tissue  
Various embodiments provide a method of treating fibrous soft tissue. The method can include the steps of targeting injured fibrous soft tissue located at or near an injury location; directing...
US20100022945 IMPLANTABLE DRUG DELIVERY SYSTEM  
An implantable medicament delivery device includes a core body which further includes a single basin or multiple smaller basins for containing a drug or a medicament. Each basin is covered by a...
US20090060977 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS  
Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical...
US20060074377 Microprojection array immunization patch and method  
Skin patches (20) having a microprojection array (10), a reservoir (18) containing an antigenic agent and an immune response augmenting adjuvant, and methods of using same to vaccinate animals...
US20150216557 Medical Tool for Reduced Penetration Force  
A medical device is provided having reduced penetration. The device includes a body having a central hollow channel and a piezoelectric transducer received within and secured to the body. The...
US20140343483 SHEATH FOR USE WITH AN ULTRASOUND ELEMENT  
An apparatus for delivering ultrasound energy and a drug solution to a treatment site in a vessel is disclosed. The apparatus includes an elongate, hollow sheath having a distal opening and an...
US20130218068 THERAPEUTICS RESERVOIR  
A method and system of forming at least one therapeutic reservoir in a target tissue by trapping therapeutics in at least a portion of said target tissue by selectively applying energy to said...
US20130211316 METHOD AND APPARATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES  
An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood...
US20120330149 Pulmonary Embolism Therapeutic Methods Using Therapeutic Inflatabel Devices and Systems  
Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Pulmonary Embolism or associated symptoms. In one series of...
US20120330148 Multiple Sclerosis Therapeutic Methods Using Therapeutic Inflatable Devices and Systems  
Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Multiple Sclerosis or associated symptoms. In one series of...
US20120220866 Deep Vein Thrombosis Therapeutic Methods Using Therapeutic Inflatable Devices and Systems  
Methods and devices are disclosed that, in various embodiments and permutations and combinations of inventions, diagnose and treat Deep Vein Thrombosis or associated symptoms. In one series of...
US20110238003 METHOD FOR SYSTEMIC DRUG DELIVERY THROUGH THE NAIL  
A method for systemically delivering a pharmaceutical composition to a human or animal, said method comprising forming an orifice in a nail of a human or animal by means of a laser-based device...
US20100331764 Controlling A Phacoemulsification Surgical System By Transitioning Between Pulse and Burst Modes  
Methods of manipulating pulses of ultrasonic energy for use with an ophthalmic surgical device.
US20100280432 BIOSYNCHRONOUS TRANSDERMAL DRUG DELIVERY  
Systems and methods for treating diseases, addictions and disorders in humans and animals involving synchronizing and tailoring the administration of drug compounds with the body's natural...
US20100174302 ROTATIONAL ATHERECTOMY SYSTEM AND METHODS OF USE  
An elongate tubular body extends between a rotatable cutter and a control. The cutter is connected to the control with a rotatable element. Material that has been processed by the cutter is drawn...
US20080319375 Materials, Methods, and Systems for Cavitation-mediated Ultrasonic Drug Delivery in vivo  
Materials, methods, and systems for targeted and non-targeted therapeutic delivery in vivo utilizing cavitation-mediated ultrasonic drug delivery are described. Noninvasive sonic energy being...
US20060264893 METHOD AND DEVICE FOR ABRADING SKIN  
A device includes a plurality of microneedles for abrading the stratum corneum of the skin to form a plurality of grooves in the tissue having a controlled depth and width. The microneedles have a...
US20050215942 Small vessel ultrasound catheter  
An ultrasound catheter adapted for accessing small vessels in the distal anatomy is disclosed. The ultrasound catheter comprises an elongate tubular body formed with a delivery lumen. The...
US20050153873 Frequency assisted transdermal agent delivery method and system  
An apparatus and method for transdermally delivering a biologically active agent comprising a delivery system having a microprojection member (or system) that includes a plurality of...
US20050065461 Ultrasonically enhanced substance delivery method  
A method for enhancing delivery of at least one substance through a surface of and into a subject. The method includes situating the substance adjacent to the surface of the subject. The method...
US20050038377 Ultrasonically enhanced substance delivery system and device  
A system for enhancing delivery of at least one substance situated substantially adjacent to a surface of a subject through the surface and into the subject. The device includes at least one...
US20170182302 METHOD AND APPRATUS FOR TREATMENT OF INTRACRANIAL HEMORRHAGES  
An ultrasound catheter with a lumen for fluid delivery and fluid evacuation, and an ultrasound source is used for the treatment of intracerebral or intraventricular hemorrhages. After the catheter...
US20160302822 Direction Reversing Vascular Treatment Device  
An apparatus for performing a vascular treatment includes an intraluminal member that is controllingly moved during the vascular treatment. The intraluminal member of the vascular treatment device...
US20130177500 ANTI-DESPR INHIBITORS AS THERAPEUTICS FOR INHIBITION OF PATHOLOGICAL ANGIOGENESIS AND TUMOR CELL INVASIVENESS AND FOR MOLECULAR IMAGING AND TARGETED DELIVERY  
Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof, including fully human, composite engineered human, humanized, monoclonal, and polyclonal anto-DEspR...
US20120089080 TISSUE REMOVAL DEVICES, SYSTEMS AND METHODS  
A tissue removal device includes a cannula that can aspirate tissue under a vacuum applied in the cannula, and a hermetically sealed fluid regulator in fluid communication with the cannula that...
US20110137231 Phacoemulsification Hand Piece With Integrated Aspiration Pump  
An ophthalmic surgical hand piece comprises a driver coupled to a horn. The horn is coupled to a needle. An aspiration pump is integral with the hand piece and is located close to the needle. A...
US20100094196 Systems and methods for delivering agents into targeted tissue of a living being  
The systems basically comprise a delivery system for accessing the targeted tissue within the living being and introduction of at least one agent at select locations in the into the myocardium and...
US20090209856 TWO-PHASE SURGICAL PROCEDURE FOR CREATING A PNEUMOSTOMA TO TREAT CHRONIC OBSTRUCTIVE PULMONARY DISEASE  
A two-phase surgical procedure is disclosed for creating a pneumostoma to treat chronic obstructive pulmonary disease The first phase is a procedure to induce creation of a localized pleurodesis...
US20090088665 MARKER DEVICE AND METHOD OF DEPLOYING A CAVITY MARKER USING A SURGICAL BIOPSY DEVICE  
A biopsy marker introduction assembly is configured for introduction through a specimen retrieval recess into a probe cutter lumen of a handheld breast biopsy handle. Advancing the cutter causes...
US20080214987 Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances  
A system and method of using a high-aspect ratio microdevice for treating, preventing or ameliorating a medical condition is provided.
US20070265560 Ultrasound Therapy System  
In one embodiment of the present invention, a system for treating an occlusion within a patient's vasculature with ultrasonic energy comprises a catheter configured to be passed through the...
US20070161945 Therapeutic ultrasound system  
An ultrasound system has a catheter including an elongate flexible catheter body having a main lumen extending longitudinally therethrough. The catheter further includes an ultrasound transmission...
US20060264809 Ultrasound catheter with cavitation promoting surface  
In one embodiment of the present invention, a method of applying ultrasonic energy to a treatment site within a patient's vasculature comprises positioning an ultrasound radiating member at a...
US20150045723 COMPOSITIONS, METHODS AND APPARATUS FOR USE WITH ENERGY ACTIVATIBLE MATERIALS  
Various different delivery devices for use in ultrasound based treatments are disclosed. Additionally, methods of using the delivery devices are also disclosed.
US20140024903 Abrading Balloon Catheter for Extravasated Drug Delivery  
A method of extravasated drug delivery is disclosed, including inserting a catheter with a first balloon, a second balloon, and a third balloon positioned between the first and second balloons and...
US20130072854 MICROBUBBLE COMPLEXES AND METHODS OF USE  
The present invention relates to a microbubble complex comprising a microbubble having an outer shell comprising a mixture of native and denatured albumin encapsulating a perfluorocarbon gas, a...
US20120083727 DRUG DELIVERY BLADE AND METHODS FOR DELIVERING A DRUG DEPOT TO A TARGET SITE  
A drug delivery blade for delivering a drug depot to a treatment site in a patient is disclosed. The drug delivery blade includes a shaft defining a longitudinal axis of the blade, a lumen that...
US20110313343 Phacoemulsification Fluidics System Having a Single Pump Head  
A phacoemulsification fluidics system for irrigating and aspirating a surgical site includes a sterile solution reservoir, an irrigation path configured to extend from the sterile solution...
US20110282268 Methods and Systems for Delivery of Fluids and Aerosols to Tissue Surfaces, Cavities and Obstructed Passages such as Intranasal Ostia  
Methods and systems for delivering fluids, aerosols, and/or acoustic energy to target sites on tissue surfaces and within body cavities or lumens, obstructions or undesired materials associated...
US20100286594 Device for Treating Hardened Lesions and Method of Use Thereof  
A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a...
US20100092424 Method of diagnosis and treatment of tumors using high intensity focused ultrasound  
A method of diagnosis and treatment of tumors using High Intensity Focused Ultrasound is provided. The method of diagnosing the presence of a tumor in a patient comprises the steps of subjecting a...
US20090312693 SYSTEM AND METHOD FOR DELIVERING ENERGY TO TISSUE  
Systems and methods for noninvasive skin treatment and deep tissue tightening are disclosed. An exemplary method and treatment system are configured for controlled thermal energy delivery to treat...
US20090024076 Nozzle for ultrasound wound treatment  
A nozzle for ultrasound wound treatment comprising a main body with proximal and distal ends, a reservoir and valve. The proximal end of the nozzle being removably attached to an ultrasound...