Match Document Document Title
US20130331585 CYCLOPROPYL PIDA BORONATE  
Provided are protected cyclopropylboronic acids that include a substituted cyclopropyl group and a boronic ester group having a protecting group. The protecting group is a pinene-derived...
US20090253709 SYNTHESIS, TELOMERASE INHIBITION AND CYTOTOXIC STUDIES ON 2,7-DISUBSTITUTED ANTHRAQUINONE DERIVATIVES  
An series of 2,7-disubstituted anthraquinone derivatives including a formula I are provided. R is a first substituted group selected from a group consisting of a hydrogen, an amino group, a nitro...
US20070149494 Method for producing 5alpha-pregnane derivative  
The present invention relates to a method of producing 5α-pregnane derivatives represented by the formula (II), which is characterized by reacting a pregnane derivative represented by the formula...
US20120226019 COMPOUNDS AND METHODS FOR PURIFYING PEPTIDES PRODUCED BY SOLID PHASE PEPTIDE SYNTHESIS  
The invention relates to compounds which can be used for purifying peptides produced by solid phase peptide synthesis. In addition, the invention relates to methods for purifying peptides produced...
US20120215006 SYNTHESIS OF PHOSPHORIC ESTERS  
The present invention relates to a process for the preparation of phosphoric esters, and to selected compounds.
US20120071570 NOVEL ACYL ACIDIC AMINO ACID ESTER  
Provided is a novel oily material that spreads smoothly upon application and is free from stickiness, and also gives ungreasy and moisturized feeling after application, but does not give friction...
US20110269905 Polymerizable Monomer, Graft Copolymer, and Surface Modifier  
The graft copolymer comprises a polymerizable monomer (A1) represented by general formula (III) and a polymerizable monomer (B1) containing a pyridyl group, and a ligand can be bonded via the...
US20100292201 NOVEL STEROIDAL ESTERS OF 17-OXIMINO-5-ANDROSTEN-3BETA-OL  
The present invention relates to steroidal esters of 17-oximino-5-androsten-3-ol, of compound of general formula (A) wherein R is selected from a group consisting of arylalkyl, aryl, substituted...
US20100074880 POLYETHYLENE GLYCOL DERIVATIVE  
The present invention includes a novel polyethylene glycol derivative; a drug carrier comprising the derivative; and a pharmaceutical composition comprising the drug carrier having a...
US20150119373 NOVEL BETULINIC ACID DERIVATIVES AS HIV INHIBITORS  
The invention relates to novel betulinic acid derivatives and related compounds, and pharmaceutical compositions useful for therapeutic treatment of viral diseases and particularly HIV mediated...
US20130004967 MICROWELL ARRAY ARTICLES AND METHODS OF USE  
The disclosure provides microstructured articles and methods useful for detecting an analyte in a sample. The articles include microwell arrays. The articles can be used with an optical system...
US20110053902 AMINO DERIVATIVES OF ANDROSTANES AND ANDROSTENES AS MEDICAMENTS FOR CARDIOVASCULAR DISORDERS  
Compounds of formula (I) wherein: the groups are as defined in the description, are useful for the preparation of medicaments for the treatment of cardiovascular disorders, in particular heart...
US20100292184 17BETA-CYANO-19-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE  
The 17β-cyano-19-androst-4-ene derivatives of the present invention possess gestagenic activity. They have the general chemical formula 1, in which Z is selected from the group comprising O, two...
US20100137622 INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11beta-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS  
The present invention relates to a process for the synthesis of the known 17-acetoxy-11-β-[4-(dimethyl amino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione (further on CDB-4124) of formula...
US20070203106 Method for Producing 5Alpha-Pregnane Derivative  
The present invention relates to a method of producing 5α-pregnane derivatives represented by the formula (III), which is characterized by selectively reducing a carbon-carbon double bond of a...
US20170174719 PROCESS FOR THE PURIFICATION OF FLUTICASONE PROPIONATE USING A KETONE SOLVENT AND WATER AS ANTI-SOLVENT  
The present disclosure relates to an improved process for the purification of fluticasone propionate by: a) dissolving fluticasone propionate in a ketone solvent to produce a mixture, b) heating...
US20170158729 METHOD OF SYNTHESIZING 25-HYDROXY CHOLESTEROL  
The present invention discloses a method for synthesizing 25-hydroxy cholesterol. The method is as below: subjecting 24-dehydrocholesterol derivative as a raw material, which undergoes an addition...
US20170158620 COMPOUND WITH BRANCHING ALKYL CHAINS, METHOD FOR PREPARING THE SAME, AND USE THEREOF IN PHOTOELECTRIC DEVICE  
The invention discloses a compound having branching alkyl chains, the method for preparing the same and use thereof in photoelectric devices. By applying the branching alkyl chains as the...
US20170152281 Crystalline solvate forms of a pharmaceutical  
The invention provides and describes solid state 17α-ethynyl-androst-5-ene-3β,7β,17β-triol including amorphous and crystalline forms and specific polymorphic forms thereof. Anhydrates and solvates...
US20170152223 LIPID PARTICLES WITH CATIONIC LIPIDS FOR RNA DELIVERY  
What is described is a lipid particle comprising the compound of formula I wherein R1 consists of alkyl, alkenyl, alkynyl, or cholesteryl;R2 consists of alkyl or alkenyl;L1 consists of alkyl,...
US20170121426 BINDING PARTNERS SPECIFIC FOR VITAMIN D EPIMERS  
Antibodies are raised against compounds of Formula (I) where Z is an immunogenic carrier. These compounds are capable of binding specifically to corresponding antibodies. The antibodies are...
US20170114088 PROCESS FOR THE PREPARATION OF 17-DESOXY-CORTICOSTEROIDS  
The present invention provides an improved process for the preparation of 17-desoxy corticosteroid derivatives in a single chemical step by reacting the 17-hydroxy starting material with an excess...
US20170114012 COMPOSITIONS RELATING TO VITAMIN D  
This invention relates to compositions, methods and kits for determining the presence and/or amount of vitamin D analytes, including vitamin D isomers, and metabolites thereof in a sample...
US20170088578 Method for Monofluoromethylation of Organic Substrates to Prepare Biologically Active Organic Compounds  
Described is a process for the preparation of monofluoromethylated organic biologically active compounds using monofluoromethylated reagents. Fluticasone Propionate and Fluticasone Furoate can be...
US20170067861 TEMPERATURE-RESPONSIVE MONOLITHIC POROUS BODY, METHOD FOR PRODUCING SAME, AND TEMPERATURE-RESPONSIVE CHROMATOGRAPHY METHOD USING SAME  
A temperature responsive monolithic porous material is obtained that comprises a polymer having a hydration ability that changes in a temperature range of 0 to 80° C. and being immobilized to a...
US20170051006 SHIP INHIBITORS AND USES THEREOF  
The present invention relates to SHIP inhibitor compounds and methods for using these compounds. In particular, the present invention discloses the following methods: (i) a method of treating...
US20170044207 PROCEDURE FOR THE PREPARATION OF ABIRATERONE ACETATE AND INTERMEDIATES THEREOF  
Disclosed is a process for the preparation of abiraterone and abiraterone acetate with high yields and purity. A key element of the method is the isolation of a crystalline intermediate that makes...
US20170036986 METHOD FOR EXTRACTING ACTIVE PRINCIPLES FROM ANTRODIA CAMPHORATA  
A method for extracting active principles from fruiting bodies of Antrodia camphorata comprises the steps of: extracting fruiting bodies of Antrodia camphorata with hot water to obtain extracts...
US20160375137 TARGETING LIPIDS  
The present invention provides targeting lipids of structure L100-linker-L101 (CI), where L100 is a lipid, lipophile, alkyl, alkenyl or alkynyl, L101 is a ligand or...
US20160355684 ANTHRAQUINONE DYE USED FOR A COLOR FILTER OF A LCD  
An anthraquinone compound which is suitable for forming a color filter used for a liquid crystal display device, a composition containing a resin and the anthraquinone compound, an article having...
US20160318972 PREPARATION METHOD AND ANALYTIC METHOD FOR THE EXTRACT OF ANTRODIA CINNAMOMEA  
An optimal preparation and analytic method for the extraction of Antrodia cinnamomea is disclosed. The important parameters for the extraction efficiency of the extract are analyzed using...
US20160311852 METHODS FOR THE SYNTHESIS OF CERAGENINS  
Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer,...
US20160311851 METHODS FOR THE SYNTHESIS OF CERAGENINS  
Disclosed herein are methods of making ceragnenin compounds for treating, preventing, or diagnosing diseases, disorders, or conditions associated with bacterial or viral infections, cancer,...
US20160297848 A PROCESS FOR THE PRODUCTION OF 19-NORPREGN-4-EN-3,20-DIONE-17ALPHA-OL(GESTONORONE) AND INTERMEDIATES THEREFOR  
The present invention relates to a new stereoselective process for the synthesis of 17(α)-17-acetyl-17-hydroxy-estr-4-en-3-one of formula (I), as well as to the new intermediates of the process....
US20160271145 METHOD FOR ENLARGING THE PARTICLE SIZE OF CRYSTALLINE MICROPARTICLES OF ACTIVE SUBSTANCE  
A method for enlarging the particle size of crystalline microparticles of active substance by providing a first suspension prepared from crystalline microparticles of active substance with a first...
US20160264615 Nuclear Sulfated Oxysterol, Potent Regulator of Lipid Homeostasis, for Therapy of Hypercholesterolemia, Hypertriglycerides, Fatty Liver Diseases, and Atherosclerosis  
The sulfated oxysterol 5-cholesten-3β, 25-diol 3-sulphate, a nuclear cholesterol metabolite that decreases lipid biosynthesis and increases cholesterol secretion and degradation, is provided as an...
US20160263127 17 Alpha, 21-Dihydroxypregnene Esters as Antiandrogenic Agents  
The present application provides 17 and/or 21 esters of 17α,21-Dihydroxypregna-4,9(11)-diene-3,20-dione and 17α,21 -dihydroxypregna-4-ene-3,20-dione having remarkable antiandrogenic activity,...
US20160244480 ENRICHMENT OF TRITERPINE ESTERS  
A new process for enriching triterpene esters comprising: providing a mixture comprising a non-distilled vegetable oil and/or a non-distilled vegetable fat, further comprising triterpene esters,...
US20160244392 SIDE-CHAIN VARIANTS OF REDOX-ACTIVE THERAPEUTICS FOR TREATMENT OF MITOCHONDRIAL DISEASES AND OTHER CONDITIONS AND MODULATION OF ENERGY BIOMARKERS  
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis,...
US20160215014 Preparation and Uses of Obeticholic Acid  
The present invention relates to obeticholic acid: or a pharmaceutically acceptable salt, solvate or amino acid conjugate thereof. Obeticholic acid is useful for the treatment or prevention of a...
US20160200671 CRYSTALLINE SALTS OF (4S, 4AS, 5AR, 12AS)-4-DIMETHYLAMINO-3,10,12,12A-TETRAHYDROXY-7-[(METHOXY(METHYL)AMINO)-METHYL]-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDRO-NAPHTHACENE-2-CARBOXYLIC ACID AMIDE AND METHODS OF USING THE SAME  
A crystalline mono hydrochloride salt of (4S,4aS,5aR,12aS)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7 -[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11 ,12a-octahydro-naphthacene-2-carbo...
US20160195556 25-OH VITAMIN D DERIVATIVES FOR DETERMINING VITAMIN D METABOLITES  
The present invention relates to new vitamin D compounds which are bonded to a labelling group at the C3 stereocentre by means of a linker. The present invention further relates to a method for...
US20160194351 Progesterone Phosphate Analogs and Uses Related Thereto  
This disclosure relates to progesterone phophate derivatives and uses related thereto. In certain embodiments, the disclosure relates to compounds disclosed herein and uses for managing...
US20160194282 A Process For Preparation Of Saxagliptin And Its Hydrochloride Salt  
Described is an improved and industrially feasible process for the preparation of Saxagliptin or its hydrochloride salt. Also described are the novel intermediates and their use in the preparation...
US20160193225 (17-ß)-3-OXOANDROST-4-EN-17-YL UNDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE  
Disclosed herein are compositions having a lipophilic active agent and methods of their use.
US20160193151 DOSAGE FORM INCORPORATING AN AMORPHOUS DRUG SOLID SOLUTION  
The dissolution of Active Pharmaceutical Ingredients in polymeric melts plays an important role in the manufacturing of drugs that use polymers as excipients. The dissolution kinetics is essential...
US20160185969 CURABLE COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR MANUFACTURING COLOR FILTER, SOLID-STATE IMAGE PICKUP ELEMENT, PICTURE DISPLAY DEVICE, AND TRIARYLMETHANE COMPOUND  
Provided are a curable coloring composition which is useful for formation of a colored pattern of a color filter, having high heat resistance, excellent solvent resistance, and a high voltage...
US20160185815 BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS AND METHODS OF USE THEREOF  
The present invention provides compounds of Formula I, pharmaceutical compositions comprising these compounds and methods of using these compounds to prevent or treat FXR-mediated or TGR5-mediated...
US20160184325 POLYHYDROXYLATED BILE ACIDS FOR TREATMENT OF BILIARY DISORDERS  
The invention provides, in part, polyhydroxylated bile acids for treating biliary disorders, for example, biliary disorders arising out of cholestasis of portal hypertension. The invention also...
US20160184320 BIOAVAILABLE SOLID STATE (17-SS;)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS  
Disclosed are bioavailable solid state (17-β)-Hydroxy-4-Androsten-3-one esters suitable for pharmaceutical uses and administration to mammals in need of (17-β)-Hydroxy-4-Androsten-3-one.