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US20080193432 Compounds Having Estrogenic Activity  
The present invention provides compounds having estrogenic activity selected from the group consisting of RRR-α-tocopherol, hydro-Q9 chromene, coenzyme Q9, cycloartane, 1-Feruloyl glycerol,...
US20140275517 METHODS AND SYSTEMS FOR CONDITIONING OF PARTICULATE CRYSTALLINE MATERIALS  
Methods and systems for the preparation of conditioned micronized active agents. Additionally, methods and systems for in-process conditioning of micronized active agent particles and compositions...
US20130101994 Method of Analysing a Cell or Other Biological Material Containing a Nucleic Acid  
According to the invention there is provided a compound of Formula (I) in which: A is a C2-8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4...
US20050009797 Androstane derivative having substituent in 7- abd 17--positions  
A compound of Formula (I): [wherein R1 represents a lower alkyl group, X represents an oxygen atom or a methylene group, m represents an integer of 1 to 10, and n represents an integer of 0 to 5]...
US20070135390 Phosphate derivatives  
According to the invention, there is provided a phosphate derivative of a phenolic hydroxy compound comprising the reaction product of the following steps: (d) reacting the phenolic hydroxy...
US20070049564 9-Aminocarbonylsubstituted derivatives of glycylcyclines  
This invention provides compounds of Formula I having the structure where R1, R2, R3 and A are defined in the specification or a pharmaceutically acceptable salt thereof useful as antibacterial...
US20140066416 BETULONIC AND BETULINIC ACID DERIVATIVES  
The present invention relates to betulonic and betulinic acid derivatives and, in particular, to C-28 and C-3 derivatives. The present invention relates to betulonic acid esters, and...
US20120012822 AROMATIC COMPOUND AND METHOD FOR PRODUCING SAME  
An aromatic compound represented by the following formula (1). [In the formula, ring A and ring B each represent a benzene ring, an aromatic fused ring composed of 2-4 rings, a heteroaromatic ring...
US20050176953 Phenanthrene derivatives and organic light-emitting diodes containing said phenanthrene derivative  
The present invention discloses a phenanthrene derivative having the following structure: wherein Ar1 and Ar2 independently are phenyl, nathphyl, heterocyclic group, polycyclic aromatic or...
US20140187722 POLYMERIC COMPOSITIONS AND METHOD OF MAKING AND ARTICLES THEREOF  
Described herein is a composition comprising at least one of: X—R—(Z)n wherein X is selected from: an aziridine amide, an aziridine urea, an isocyanate, an alcohol, an amine, an epoxy, or a...
US20090177002 Method For Preparing Indene Derivatives, And Intermediates For Preparation Of Derivatives  
Indene derivatives that are utilizable as intermediates in the synthesis of the vitamin D2 derivative paricalcitol, which is useful as pharmaceutical are efficiently prepared by subjecting a...
US20140148593 PROCESS FOR PREPARING FLUTICASONE PROPIONATE/FUROATE  
The present invention relates to an improved process for the preparation of substituted Fluticasone derivatives. The invention also reveals the processes for the purification of Fluticasones and...
US20130029954 C-28 AMINES OF C-3 MODIFIED BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS  
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-28 amines of C-3 modified betulinic acid derivatives that...
US20080249036 Antagonist Against Tolerance to Anticancer Drugs  
An ABC transporter protein expression inhibitor comprising, as the active ingredient(s), 0.001 to 100 nM of one or more members selected from among steroid hormones, compounds having a female...
US20100105934 FULVESTRANT INTERMEDIATE  
A compound of formula (1) wherein R1 represents hydrogen or an acetyl group and R2 represents a methyl, acetyl, or benzyl group, is useful as an intermediate in making fulvestrant. The compound...
US20080138285 Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound  
A steroid ester compound of a terminally-fluorinated alkyl fatty acid, a steroid compound having bis(trifluoromethyl)phenyl group, a phosphatidylserine compound having a terminally-fluorinated...
US20050032794 Diamine derivatives of quinone and uses thereof  
Diamine derivatives of quinones, and related compounds, including salts thereof, that modulate the levels of gene expression in cellular systems, such as cancer cells, are disclosed, along with...
US20110306722 SURFACE-MODIFIED POLYMER FILMS  
Surface-modified polymer films for coating are provided, wherein the surface is modified by covalent binding of nano- or micro-particles comprising a photoreactive species. The surface of the...
US20060014729 Compounds and their preparation for the treatment of Alzheimer's disease by inhibiting beta-amyloid peptide production  
The present invention provides novel dammarane compounds, compositions (e.g., pharmaceutical compositions) comprising the dammarane compounds, and methods for the synthesis of these dammarane...
US20090048218 17Beta-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE  
The 17β-cyano-18a-homo-19-nor-androst-4-ene derivatives of the present invention possess gestagenic activity. They have the general chemical formula 1, in which Z is selected from the group...
US20130053586 Novel Ecdysterone Synthesis Derivative, Preparation Method and Use Thereof  
This invention discloses a novel compound with the structure of formula I, or pharmaceutically acceptable salts or solvates thereof. In addition, the invention further discloses a method for...
US20120035116 BILE ACIDS AND BIGUANIDES AS PROTEASE INHIBITORS FOR PRESERVING THE INTEGRITY OF PEPTIDES IN THE GUT  
This invention relates to methods of preserving the integrity of peptides in the gut. In particular it concerns the use of certain compounds as inhibitors of gut proteases. Compounds identified as...
US20150018569 METHOD FOR PREPARING A HERBICIDAL COMPOUND  
The present invention discloses a simple method for transforming cashew nut shell liquid into an active herbicidal composition.
US20090023698 METHODS OF MANUFACTURING BIOACTIVE 3-ESTERS OF BETULINIC ALDEHYDE AND BETULINIC ACID  
The present invention provides a method for preparing a compound of formula (I), the method comprising contacting a compound of formula (II) with an effective amount of a compound of formula (III)...
US20100035796 17-ALPHA-SUBSTITUTED DERIVATIVES OF ESTRADIOL WITH WOUND-HEALING ACTIVITY  
The invention relates to 17α-(5-hydroxy-C5-hydrocarbyl)-1,3,5(10)-estratrien-3,17β-di ol derivatives having cicatrising activity, preferably for topical use on wounds, without significant systemic...
US20080039643 Process for the Preparation of Phenolic Hydroxy-Substituted Compounds  
The invention relates to a process for the preparation of a phenolic hydroxy-substituted compound of the general formula (I) by desalkylation of an alkyl aryl ether of the general formula (II) by...
US20070161808 Process for the preparation of aq4n  
A process for the preparation of compound AQ4N of formula (2) or a salt or solvate thereof wherein the said process includes the reaction step: Formula (1), Formula (2), where compound AQ4 of...
US20150148524 AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS  
A method for the synthesis of an amino acid analogue or a salt, solvate, derivative, isomer or tautomer thereof comprising the steps of: (i) subjecting an amino acid containing a metathesisable...
US20090203662 NOVEL DERIVATIVES OF CHOLEST-4-EN-3-ONE OXIME, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PREPARATION METHOD  
The object of the invention is the use as a drug of a compound fitting formula I wherein X represents an oxygen atom or a ═N—OH group and R represents a group selected from or one of its esters...
US20140378645 LIQUID CRYSTAL ALIGNING AGENT  
A problem of the present invention is to provide a liquid crystal aligning agent which never deteriorates even in a method where UV is irradiated such as a liquid crystal dropping method or the...
US20110040112 METHOD FOR MAKING 3A-HYDROXY, 3B- SUBSTITUTED-5A-PREGNAN-20-ONES  
Applicants have discovered a method for the stereoselective and regioselective synthesis of 3α-hydroxy, 3β-methyl-5α-pregnan-20-one (ganaxolone) comprising reacting 5α-pregnane-3,20-dione; with an...
US20080249077 17.Beta.-Fluoromethoxycarbonyl-Androst-4-En-3-One Compounds With a 17.Alpha.-Carbonate Sustituent  
The present invention is directed to compounds of formula (I): wherein R1 represents C4-C7 branched chain alkyl, C3-C8 cycloalkyl optionally substituted by one or more groups independently...
US20130006003 NEW SYNTHONES FOR PREPARATION OF 19-NOR VITAMIN D DERIVATIVES  
The present invention discloses the synthone of Formula (I), wherein R1 and R2 are the same or different and represent independently hydrogen atom or hydroxyl protecting group, and its use for...
US20090105491 OPTICALLY ACTIVE DIAMINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME  
The invention is directed to a process for producing intermediates of a compound which exhibits an activated blood coagulation factor Xa inhibitory action and which is a useful preventive and a...
US20090069448 Degradable polymer and process for production thereof  
In one embodiment of the present invention, a degradable polymer having a peroxide bond therein is disclosed. The degradable polymer can be utilized in the fields of medicals or medical materials,...
US20100286417 Crystalline Minocycline Base and Processes for its Preparation  
The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form II and Form III, of minocycline base are provided. These are...
US20090048217 17Beta-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, ITS USE AND MEDICAMENTS COMPRISING THE DERIVATIVE  
The 17β-cyano-19-nor-androst-4-ene derivatives of the present invention possess gestagenic activity. They have the general chemical formula 1, in which Z is selected from the group comprising O,...
US20050148561 Novel triterpene derivatives, preparation thereof and use thereof  
The present invention relates to novel synthetic derivatives of triterpenes and the use of such derivatives as pharmaceuticals. The present invention is directed to novel compounds of Formula I:...
US20120316319 ARYLETHYNYLXANTHENE DYES  
Disclosed are 9-arylethynylxanthenes which possess useful fluorescent properties, and can be used as fluorescent dyes, and labels.
US20090143340 Pyrocatechin Derivatives  
Pyrocatechin derivatives of formula I wherein R illustrates a group of formulae Ia, Ib, Ic or Id R1 is 4-halogen-but-2-enyl, R2 is lower alkyl or cycloalkyl, R3 is lower alkoxy and R4 is lower...
US20090131384 COMPOUNDS AND METHODS FOR TREATMENT OF DISORDERS ASSOCIATED WITH ER STRESS  
The invention provides novel compounds, methods for treating or preventing a condition related to ER-stress, e.g. hypercholesterolemia, atherosclerosis and related conditions, and pharmaceutical...
US20080112966 Extracts and Methods Comprising Ganoderma Species  
The present invention relates to extracts of ganoderma species plant material prepared by supercritical CO2 extractions.
US20150148552 23-YNE-VITAMIN D3 DERIVATIVE  
To provide a novel vitamin D3 derivative useful as a therapeutic agent for osteoporosis. Provided is a vitamin D3 derivative represented by the following formula (1) or a medicinally acceptable...
US20130210781 23-YNE-VITAMIN D3 DERIVATIVE  
To provide a novel vitamin D3 derivative useful as a therapeutic agent for osteoporosis. Provided is a vitamin D3 derivative represented by the following formula (1) or a medicinally acceptable...
US20130072465 NOVEL BETULINIC ACID DERIVATIVES WITH ANTIVIRAL ACTIVITY  
Compounds of Formula I: that possess unique antiviral activity are provided as HIV maturation inhibitors. These compounds are useful for the treatment of HIV and AIDS.
US20120090102 ANIONIC DYE POLYMERS  
The present invention provides a laundry treatment composition comprising an anionic dye-polymer.
US20100120737 Amorphous ciclesonide  
The present invention relates to amorphous ciclesonide, methods to prepare the same, pharmaceutical compositions comprising amorphous ciclesonide as active ingredient, and methods of treatment...
US20100076171 Polymerizable liquid crystal compound, composition and polymer  
A polymerizable liquid crystal compound that has a wide liquid crystal phase temperature range and has a sterol ferulate skeleton, and a liquid crystal composition containing the compound are...
US20050032754 5,6-Trans-2-alkylvitamin D derivatives  
Object of the present invention is to synthesize novel vitamin D derivatives. The present invention provides 5,6-trans-2-alkyl-substituted vitamin D derivatives of Formula (1): wherein R1 is...
US20110118488 PROCESS FOR OBTAINING 6-ALKYLIDENANDROST-1, 4-DIENE-3-ONE  
6-alkylidenandrost-1,4-dien-3-ones of general formula (I), wherein R is H o alkyl; R1 y R2, independently of one another, represent H, OR3, OC(═O)R4 or O-(GPH), wherein R3 is H; C1-C6 alkyl or...