Matches 1 - 50 out of 64 1 2 >


Match Document Document Title
US20130261175 2-PYRONES  
The present invention relates to the use of compounds of the formula (I) for the care, preservation or improvement of the general condition or appearance of the skin or hair, and to preparations...
US20130047887 NOVEL MULTIFUNCTIONAL MOLECULES FOR DENTAL BONDING APPLICATIONS HAVING IMPROVED ADHESION  
The present invention describes dental adhesive compositions used for bonding dental biomaterials to hard tissue comprising a polymerizable blend of one or more newly synthesized low shrinkage,...
US20130245284 Prodrugs of Fluorinated Mevalonates to Inhibit the Mevalonate Pathway of Streptococcus pneumoniae  
Fluorinated prodrug compounds as can be used for selective streptococcal mevalonate pathway inhibition.
US20110184056 USE OF STATINS AS ANTICONVULSANTS, ANTIEPILEPTICS AND NEUROPROTECTORS  
The use of statins as antiepileptic, anticonvulsant, neuroprotector and antioxidant compounds, potentially useful for the prevention and/or treatment of epilepsy, epileptic seizures, convulsions,...
US20140356336 METHOD FOR INDUCING DIFFERENTIATION ENABLING TUMORIGENESIS OF IPS CELLS TO BE SUPPRESSED  
The object of the invention is to provide a technique of suppressing tumorigenesis in IPS cells and inducing differentiation into target differentiated cells. In use of a statin and a...
US20110190307 Assay  
The present invention provides zebrafish based methods for the identification of compounds potentially useful in the treatment of motor neuron degenerative diseases (MNDDs), compounds identified...
US20110054193 STATIN PRODUCTION  
The present invention relates to a polypeptide with HMG-CoA reductase activity, to its polynucleotide congener and to a method for the production of a statin comprising over expression of said...
US20120172337 CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES  
The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and...
US20150258189 HEPATITIS C VIRUS PARTICLES FORMATION PROMOTER, AND METHOD OF PRODUCING HEPATITIS C VIRUS PARTICLES  
A HCV particle formation promoter is capable of promoting formation of HCV particles in culture cells, and a method enhances production of HCV particles. A method evaluates an anti-HCV agent...
US20060084817 Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging  
Aldaric acids, aldonic acids, and their corresponding salts are cyclized to the corresponding lactone or dilactone using gas sparging to remove water.
US20060167280 Method for purifying simvastatin  
The present invention relates to a purification method of simvastatin crystal, more particularly to a method of effectively removing impurities contained in crude simvastatin obtained by a...
US20140107339 SUBSTITUTED 3-HYDROXY-DELTA-LACTONES FROM EPOXIDES  
Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.
US20060223882 Amorphous simvastatin  
Amorphous simvastatin is prepared by rapidly removing solvent from a solution comprising simvastatin. The solution can also comprise a pharmaceutically acceptable carrier, to form a dispersion of...
US20090048335 PROCESS FOR PREPARING SIMVASTATIN  
Preparation of simvastatin.
US20090156837 ISOLATION AND RECOVERY OF SIMVASTATIN IN LACTONE FORM OR IN THE FORM OF AN ACID SALT FROM THE HARVESTED FERMENTATION BROTH  
The present invention relates to a novel process for isolation and recovery of compounds such as biosynthetically produced simvastatin in either lactone form or in the form of its acid salt in...
US20120095091 ANTIEPILEPTIC, HYPOCHOLESTEROLEMIC AND NEUROPROTECTIVE COMPOUND  
The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of...
US20060084800 Synthesis of aldonolactones, aldarolactones, and aldarodilactones using azeotropic distillation  
Processes for making lactones and dilactones from aldaric acids, aldonic acids, and their corresponding salts by dehydrative cyclization and azeotropic distillation. The processes can be carried...
US20070185193 Huvastatin and its preparation and formulation comprising the huvastatin  
The invention relates to statin compounds, and it discloses novel small molecule compounds, i.e., huvastatins, which are classified into I, II, and III. The invention also provides the preparation...
US20130197073 HYPOCHOLESTEROLEMIC, ANTI-INFLAMMATORY AND ANTIEPILEPTIC NEUROPROTECTIVE COMPOUND  
The present invention describes a compound of formula (I) its hydroxy acid form, the pharmaceutically acceptable salts of said hydroxy acid and pharmaceutically acceptable prodrugs and solvates of...
US20070238780 Multifunctional enhancement systems for personal care, household, and wood products  
A personal care product, a household product, an industrial formulation, or a medicinal product of at least a fluorosurfactant and/or a natural or naturally-derived or synthetic, and/or...
US20130281493 Method for Treating Cancer Harboring a p53 Mutation  
A method for determining if a subject with cancer or precancerous lesions or a benign tumor, will respond to treatment with an inhibitor selected from the group comprising an inhibitor of one or...
US20070203334 Process for preparing a synthetic intermediate for preparation of branched nucleosides  
A process is provided for the preparation of a key intermediate in the preparation of 2′-branched nucleoside compounds. The process includes contacting a protected precursor...
US20130245101 Liver Targeted Conjugates  
Therapeutic conjugates containing a statin or a modified statin (collectively “statin”) linked to a therapeutic agent (also referred to as a drug herein) are targeted to the liver by the statin or...
US20120156216 Methods and Compositions for Treatment of Tumor Metastasis  
The various embodiments of the present invention are directed to methods and compositions for treatment, inhibition or reduction of metastasis in cancers. In particular, the invention is related...
US20100317823 Production of Adipic Acid and Derivatives from Carbohydrate-Containing Materials  
The present invention generally relates to processes for the chemocatalytic conversion of a glucose source to an adipic acid product. The present invention includes processes for the conversion of...
US20110294800 HYPOGLYCEMIC DIHYDROPYRIDONES  
The present invention provides, inter alia, a compound of formula I: wherein the substituent designations are indicated in the Specification. The present invention also provides pharmaceutical...
US20110269830 STATIN NANOPARTICLES  
The present invention relates to a complex made up of at least one molecule of statin or a derivative thereof, covalently bonded to at least one hydrocarbon radical including at least 18 carbon...
US20110282074 Process for Preparing Substantially Pure Simvastatin  
This invention relates to an improved process for preparing substantially pure simvastatin (I), chemically known as...
US20100145046 Substituted 3-hydroxy-delta-lactones from epoxides  
Catalysts and methods for the carbonylation of epoxides to substituted 3-hydroxy-δ-lactones and β-lactones are disclosed.
US20100191002 Method of Oxidization Using Nitric Acid  
A controlled nitric acid process employing oxygen and nitric acid as co-oxidants is used to oxidize organic compounds subject to nitric acid oxidation, to their corresponding carboxylic acids....
US20140206645 DUAL ACTION INHIBITORS AGAINST HISTONE DEACETYLASES AND 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE  
Disclosed herein are novel compounds of formula (I), and uses thereof. The compounds of Formula (I) are inhibitors of histone deacetylases (HDACs) and 3-hydroxy-3-methylglutaryl coenzyme A...
US20110294783 Insecticidal Compositions Having Improved Effect  
The present invention concerns boosting the activity of crop protection materials comprising inhibitors of fatty acid biosynthesis (for example phenyl-substituted cyclic ketoenols) through the...
US20110021592 ORGANIC NANOPARTICLES OBTAINED FROM MICROEMULSIONS BY SOLVENT EVAPORATION  
The present invention provides a process for preparing a redispersible powder of nanoparticles of a water-insoluble organic compound, the process including the steps of: (i) preparing an...
US20120190870 ANTITUMORAL DIHYDROPYRAN-2-ONE COMPOUNDS  
Antitumoral compounds obtained from a porifera, of the family Raspailiidae, genus Lithoplocamia, species lithistoides, and derivatives thereof are provided.
US20130309187 SKIN-WHITENING AGENT CONTAINING 3-HYDROXY-2-PYRONE  
This invention provides a skin-whitening agent, a tyrosinase activity inhibitor, and melanin production inhibitor comprising, as an active ingredient, a compound exhibiting excellent solubility in...
US20110178043 Inhibitors of the mevalonate pathway of streptococcus pneumoniae  
Compounds and related methods as can be used for selective mevalonate pathway inhibitors.
US20060083678 Radio-labeled compounds, compositions, and methods of making the same  
18F radio-labeled compounds, methods of making the radio-labeled compounds, and applications of the same are disclosed.
US20080319211 PROCESS FOR THE PREPARATION OF EPOTHILONES  
Intermediates in the preparation of epothilones and epothilone analogs are provided along with synthetic methods useful in the synthesis of epothilone compounds.
US20140256960 GENE EXPRESSION CASSETTE AND A TRANSFORMANT, AND A METHOD FOR MANUFACTURING 2-DEOXY-SCYLLO-INOSOSE AND A METHOD FOR PURIFYING 2-DEOXY-SCYLLO-INOSOSE USING SAID TRANSFORMANT  
A transformant is prepared to insert at least a gene expression cassette comprising a gene involved in the synthesis of 2-deoxy-scyllo-inosose into E. coli as host cells. A 2-deoxy-scyllo-inosose...
US20120232290 REACTIVITY OF HYDROXYMETHYLGLUTARYL COENZYME A (HMG-COA) REDUCTASE INHIBITORS CONTAINING CONJUGATED DIENES WITH PHENOLIC ANTIOXIDANTS IN THE SOLID-STATE  
The object of this invention was to probe the reactivity of lovastatin, simvastatin, pravastatin, and mevastatin in the solid-state without radical initiators in order to determine the antioxidant...
US20090171095 PRODUCTION METHOD OF HETEROCYCLIC MERCAPTO COMPOUND  
A method of the invention industrially produces heterocyclic mercapto compounds useful as raw materials or intermediates in the synthesis of medicaments or pesticides, or as permanent wave agent,...
US20120296099 METHODS FOR PREPARING STATIN COMPOUNDS BY LACTONIZATION  
A method for preparing a statin compound by lactonization is disclosed, which comprises the following step: lactonizing a compound of formula II into the compound of formula I in the presence of a...
US20100183563 DENTINOGENESIS PROMOTER AND DENTINOGENIC PULP-CAPPING MATERIAL  
The present invention provides a dentinogenesis inducer and dentinogenesis pulp-capping material, which are effectively used for formation (regeneration) of dentin. The present invention also...
US20100137244 PREPARATION AND UTILITY OF HMG-COA REDUCTASE INHIBITORS  
Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers,...
US20120070511 MITOCHONDRIAL INHIBITORS AND USES THEREOF  
Compositions which modulate mitochondrial functions treat diseases associated with cells that are hyperactively using their endoplasmic reticulum. Screening assays identify agents which modulate...
US20110077380 CARBOHYDRATE LACTONE POLYMERS  
The present invention relates to a novel carbohydrate lactone, functionalized aliphatic polyesters and copolymers formed therefrom, and processes for the preparation thereof from renewable resources.
US20100274029 METHOD OF PREPARING (6R)-3-HEXYL-4-HYDROXY-6-UNDECYL-5, 6-DIHYDROPYRAN-2-ONE, AND INTERMEDIATE USED IN THE METHOD  
Provided is a method of preparing a (6R)-3-hexyl-4-hydroxy-6-undecyl-5,6-dihydropyran-2-one, and a (5R)-2-hexyl-5-hydroxy-3-iminohexadecanoate derivative used in said method as an intermediate.
US20110251406 PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED-1,-3-DIOXANE-4-YL) ACETIC ACID DERIVATIVES  
The invention relates to the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives of formula (1), where X stands for a leaving group, and R1, R2, and R3 each independently...
US20130345429 PROCESS AND INTERMEDIATE COMPOUNDS USEFUL IN THE PREPARATION OF STATINS  
There is provides a process for the preparation of a compound of formula (7): wherein R is an optionally substituted hydrocarbyl group or an optionally substituted heterocyclic group; provides...
US20120323011 PROCESS AND INTERMEDIATE COMPOUNDS USEFUL IN THE PREPARATION OF STATINS  
There is provides a process for the preparation of a compound of formula (7): wherein R is an optionally substituted hydrocarbyl group or an optionally substituted heterocyclic group; provides...

Matches 1 - 50 out of 64 1 2 >