Matches 1 - 34 out of 34


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US20120165380 METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS  
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an...
US20120035235 METHODS OF TREATING ALPHA ADRENERGIC MEDIATED CONDITIONS  
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an...
US20110160265 METHOD OF TREATING MOTOR DISORDERS WITH ALPHA-2B ADRENERGIC RECEPTOR AGONISTS  
Disclosed herein is a method of treating motor disorders comprising administering to a subject in need of such treatment an alpha-2 receptor agonist lacking significant alpha-2A receptor activity.
US20110053901 ACETYL MIMIC COMPOUNDS FOR THE INHIBITION OF ISOPRENYL-S-CYSTEINYL METHYLTRANSFERASE  
Among other things, the present invention provides novel compounds capable of effectively inhibiting inflammatory responses that are mediated by G-proteins or GPCRs in neutrophils, macrophages and...
US20110218208 2-HETEROCYCLYLAMINOALKYL-(P-QUINONE) DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISEASES  
Methods of treating or suppressing oxidative stress disorders including mitochondrial diseases, impaired energy processing disorders, neurodegenerative diseases and diseases of aging are...
US20150183770 5-RING HETEROAROMATIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS  
The invention relates to 5-ring heteroaromatic compounds of general formula (I), their use for the treatment and/or prevention of diseases, and medicaments containing same.
US20110207788 5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors  
The invention relates to 5-ring heteroaromatic compounds of general formula (I), their use for the treatment and/or prevention of diseases, and medicaments containing same.
US20080293569 Indanyl- and Tetrahydronaphthyl-Amino-Azoline Compounds for Combating Animal Pests  
The present invention relates to Indanyl- and Tetrahydronaphthyl-amino-azoline compounds of formula I wherein the variables R1 and R2 are as defined in description.The invention relates also to...
US20090018150 5-Ht2b Receptor Antagonists  
Compounds of formulae: (I), (II), (IIIa), (IIIb), (IVa) and (IVb): or a pharmaceutically acceptable salt thereof, for use as pharmaceuticals, in particular for the treatment of a condition...
US20080200335 1-(Imidazolin-2-Yl)Amino-1,2-Diphenylethane Compounds For Combating Animal Pests  
The present invention relates to 1-(imidazolin-2-yl)amino-1,2-diphenylethane compounds of the formula I and their agriculturally acceptable salts, wherein A is a radical of the formula A1 or A2....
US20080280869 Pyrazole or Triazole Compounds and Their Use for the Manufacture of a Medicament for Treating Somatic Mutation-Related Diseases  
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or...
US20110214810 HYDROXYALDIMINE-CONTAINING POLYURETHANE COMPOSITION  
A composition that includes aldimines of Formula (I). The composition can be a two-component polyurethane composition. The composition can have a long open time, but build up an early strength...
US20130217739 THERAPEUTIC COMPOUNDS  
Disclosed herein is a compound having a structure compositions, methods, and medicaments related thereto are also disclosed.
US20110178143 THERAPEUTIC COMPOUNDS  
Disclosed herein is a compound having a structure compositions, methods, and medicaments related thereto are also disclosed.
US20120289698 CERTAIN HETEROCYCLES, COMPOSITIONS THEREOF, AND METHODS FOR THEIR USE  
Provided are compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, X, Z1, Z2, Z3, Z4 and m are as defined herein.Also provided is a...
US20110150819 INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES  
Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these...
US20080139481 Non-Natural Amino Acids  
This invention relates to non-natural desamino alkyl amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is...
US20140094436 IMIDAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY  
Compounds of formula (I), pharmaceutical compositions comprising compounds of formula (I) and methods of inhibiting Hsp90 in a cell, treating or preventing a proliferation disorder in a mammal and...
US20140030189 LIGANDS FOR IMAGING CARDIAC INNERVATION  
Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit...
US20140221383 CETP INHIBITORS  
Compounds having the structures of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing...
US20070088069 Novel imidazoles  
Novel imidazole compounds and pharmaceutical compositions are described, as are methods of using such compounds, alone or in combination with another pharmaceutically active agent, to treat...
US20080146634 2-IMIDAZOLES  
The present invention relates to compounds of formula I, wherein X is —CH2— or —NH—;Y is —CH(lower alkoxy)-, —CH(lower alkyl)-, —O—, —S—, —S(O)—, —S(O)2— or —CH2—; andAr is phenyl or naphthyl,...
US20100130742 TETRALIN AND INDANE DERIVATIVES AND USES THEREOF  
Compounds of the formula I, II or III: or pharmaceutically acceptable salts thereof, wherein m, n, q, Ar, R1, R2, R3, R4 and R5 are as defined herein. Also provided are methods for preparing,...
US20100221182 LIGANDS FOR IMAGING CARDIAC INNERVATION  
Novel compounds that find use as imaging agents within nuclear medicine applications (PET imaging) for imaging of cardiac innervation are disclosed. These PET based radiotracers may exhibit...
US20100087655 METHOD FOR PRODUCTION OF N-(2-AMINO-1,2-DICYANOVINYL)IMIDATES, METHOD FOR PRODUCTION OF N-(2-AMINO-1,2-DICYANOVINYL)FORMAMIDINE, AND METHOD FOR PRODUCTION OF AMINOIMIDAZOLE DERIVATIVES  
A method for producing N-(2-amino-1,2-dicyanovinyl)imidates represented by the following formula (1-III) under low temperature conditions within a short period of time in high yield is provided....
US20130029981 COMPOUNDS, COMPOSITIONS, AND METHODS FOR CONTROLLING BIOFILMS  
The invention relates to substituted 2-aminoimidazoles and their imidazo[1,2-a]pyrimidinium salts precursors being active against biofilm formation. The invention also relates to...
US20130217632 Non-Natural Amino Acids  
This invention relates in one aspect to non-natural desamino alkyl amino acid compounds, methods of making these compounds, and peptides containing these compounds. In one embodiment, the peptide...
US20100010217 METHODS FOR THE PREPARATION OF IMIDAZOLE-CONTAINING COMPOUNDS  
The present invention generally relates to methods for the preparation of compounds that contain imidazole moieties. In some embodiments, the methods include the reaction of a diamine with a...
US20080181923 INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE DERIVATIVES  
Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these...
US20100130432 Non-Natural Amino Acids and Neurotensin Analogues Thereof  
This invention relates to non-natural desamino amino acid compounds, methods of making, and peptides containing these compounds as their N-terminus moieties. A preferred example is neurotensin...
US20100137385 Insecticidal Substituted Amino Heterocyclic and Heteroaryl Derivatives  
Certain substituted amino heterocyclic and heteroaryl derivatives have provided unexpected insecticidal and acaricidal activity. These compounds are represented by formula (I): wherein R, R1, R2,...
US20080146523 IMIDAZOLE DERIVATIVES  
The invention relates to imidazole derivatives which have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1. The invention also relates to a...
US20160194288 INHIBITION OF BACTERIAL BIOFILMS AND MICROBIAL GROWTH WITH IMIDAZOLE DERIVATIVES  
Disclosure is provided for imidazole derivative compounds useful to inhibit the formation of biofilms and/or inhibit microbial growth, compositions including these compounds, devices including...
US20150266817 TETRALIN AND INDANE DERIVATIVES AND USES THEREOF  
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R1 and R2 are as defined herein. Also provided are methods for preparing, compositions comprising,...

Matches 1 - 34 out of 34