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US20130102759 Synthetic Oligosaccharides for Moraxella Vaccine  
The present invention provides synthetic Moraxella catarrhalis lipooligosaccharide (LOS)-based oligosaccharides and conjugates containing various M. catarrhalis serotype-specific oligosaccharide...
US20110076326 MODIFIED PROTEIN EXCIPIENT FOR DELAYED-RELEASE TABLET  
The present invention relates to delayed release oral formulations comprising active ingredients and modified proteins used as excipients. The proteins have chemical modifications such as...
US20130064866 PULMONARY AND NASAL DELIVERY OF SERUM AMYLOID P  
The disclosure relates to methods for delivery of serum amyloid P to the respiratory system. Pharmaceutical compositions comprising SAP suitable for respiratory delivery are also provided.
US20130259801 SERUM AMYLOID P PROTEIN  
A method for purifying serum amyloid P protein from fresh unfrozen plasma, includes recalcifying the fresh unfrozen plasma and separation by phenyl-type hydrophobic interaction chromatography. The...
US20130137595 BIOMARKERS FOR LYMPHOMA  
A biomarker, method, test kit, and diagnostic system for detecting the presence of lymphoma in a person are disclosed. The lymphoma may be Hodgkin's lymphoma or non-Hodgkin's lymphoma. The person...
US20110300641 PROTEIN ISOFORMS FOR DIAGNOSIS  
Several aspects of this invention relate to diagnosis of diabetic states in a mammal using protein isoforms. In some aspects, it relates to a method for determining the diabetic state of a mammal....
US20120195883 MONOCOT SEED PRODUCT COMPRISING A HUMAN BLOOD PROTEIN  
The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and...
US20130243697 Novel Chimeric Proteins and Methods for Using The Same  
Novel chimeric proteins are disclosed. The proteins comprise at least two portions. The first portion binds to a first cell and decreases the cell's ability to send a trans signal to a second...
US20120208982 Viral Inactivation Using Improved Solvent-Detergent Method  
The present specification discloses methods of inactivating a lipid-coat containing virus and proteins essentially free of a lipid-coat containing virus obtained from such methods.
US20140343253 PLASMA PROTEIN FRACTIONATION BY SEQUENTIAL POLYACID PRECIPITATION  
There is a recognized need for novel, more simplified, approaches to isolation of plasma from whole blood, as well as a need to isolate cell-free plasma fractions containing different plasma...
US20150065689 SINGLE STEP FRACTIONATION METHOD  
Single step method of enriching highly sialylated variant/s of a protein by use of a strong ion exchange chromatography support and a pH gradient in absence of any salt gradient.
US20120174264 Uses of Yerba Santa  
Methods of in vitro propagation of plants of the genus Eriodictyon are described, including, in particular embodiments, plants of the species E. californicum, E. trichocalyx and E. sessilifolium....
US20110059501 Protein Glycosylation  
The present invention relates to methods for glycosylating a protein in which the protein is modified to include an alkyne and/or an azide group. The invention further relates to a protein...
US20130243821 SOYBEAN DERIVED HUMAN THYROGLOBULIN, METHODS OF PRODUCING AND APPLICATIONS THEREOF  
The present invention includes novel soybean derived human thyroglobulin, methods of producing human thyroglobulin in plants such as soybean, and novel diagnostic applications for the detection...
US20110306753 Method for Increasing Protein Expression in Cells  
The present invention relates to a method for increasing the expression of a protein in cells, preferably in eukaryotic cells, by reducing the number of RNase L cleavage sites in the coding and/or...
US20120171747 SIGNAL AMPLIFICATION MICROSPHERES, THEIR USE IN ONE-STEP AND MULTI-STEP ANALYTICAL AMPLIFICATION PROCEDURES AND METHODS FOR THEIR PRODUCTION  
The present invention relates to microspheres comprising protein signal precursor molecules, or a carrier protein bonded to signal precursor molecules, wherein said signal precursor molecules are...
US20120009650 COMPOSITIONS, METHODS AND KITS FOR PREPARING PLASMINOGEN AND PLASMIN PREPARED THEREFROM  
Compositions and methods for preparing plasminogen, in particular recombinant plasminogen, and compositions and methods of utilizing same for preparing plasmin are provided.
US20140315802 Derivatisation of Erythropoietin (EPO)  
The present invention relates to a compound which is a polysaccharide derivative of EPO, or of an EPO like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide...
US20140309166 Derivatisation of Erythropoietin (EPO)  
The present invention relates to a compound which is a polysaccharide derivative of EPO, or of an EPO like protein, wherein the polysaccharide is anionic and comprises between 2 and 200 saccharide...
US20140186384 VACCINES AND METHODS FOR USING THE SAME  
Improved anti-HIV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus sequences for HIV Subtype A Envelope protein, those...
US20130029367 COMPOSITIONS AND METHODS FOR MONITORING BREAST CANCER TREATMENT  
The present invention provides compositions and processes for preparing the same wherein the compositions are useful for monitoring breast cancer treatment.
US20110027257 CLOTTABLE CONCENTRATE OF PLATELET GROWTH FACTORS AND PREPARATION METHOD THEREOF  
The present disclosure relates to a clottable concentrate of platelet growth factors for therapeutic and/or cosmetic use, preferably comprising the growth factors PDGF, TGT-β, IGF, EGF, CTGF, bFGF...
US20150031621 METHOD FOR PURIFICATION OF COMPLEMENT FACTOR H  
A method for purification of complement Factor H from a complement Factor H containing source such as blood or blood plasma, in particular a caprylate precipitate of a Factor H containing source,...
US20120196308 Methods and Kits for Measuring Von Willebrand Factor  
Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein Iba having...
US20110311505 Photosensitive Aminoacid-Monomer Linkage and Bioconjugation Applications in Life Sciences and Biotechnology  
This invention is related to preparation of photosensitive ruthenium based aminoacid monomers and oligomers, aminoacid monomer-protein cross-linking using photo sensitat ion and conjugation on...
US20110286976 BI-SPECIFIC FUSION PROTEINS  
Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair damaged...
US20130023473 METHODS AND PHARMACEUTICAL COMPOSITION FOR THE PRESERVATION OF VASCULAR ENDOTHELIAL CELL BARRIER INTEGRITY  
The invention relates to an ANGPTL4 polypeptide for use in the preservation of vascular endothelial cell barrier integrity and reduction in no-reflow phenomenon with myocardial infarction.
US20130101981 PARTICLE MATRIX FOR STORAGE OF BIOMOLECULES  
Matrices for manipulation of biopolymers, including the separation, purification, immobilization and archival storage of biopolymers is disclosed.
US20140275484 METHOD FOR PRODUCING FACTOR H FROM A PLASMA PRECIPITATION FRACTION  
The present disclosure provides, among other aspects, improved methods for the manufacture of Factor H compositions from plasma precipitation fractions. In some aspects, the methods include an...
US20130102530 Protection, Restoration and Enhancement of Erythropoietin-Responsive Cells, Tissues and Organs  
Methods and compositions are provided for protecting or enhancing an erythropoietin-responsive cell, tissue, organ or body part function or viability in vivo, in situ or ex vivo in mammals,...
US20110293594 REMOVAL OF SERINE PROTEASES BY TREATMENT WITH FINELY DIVIDED SILICON DIOXIDE  
The present invention provides novel methods for reducing the serine protease and/or serine protease zymogen content of a plasma-derived protein composition. Also provided are methods for...
US20140088294 PRODUCTION OF GLYCOPROTEINS USING MANGANESE  
Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.
US20110301079 NEUROMEDIN U RECEPTOR AGONISTS AND USES THEREOF  
Neuromedin U receptor agonists for use in the treatment of metabolic disorders such as obesity and diabetes are disclosed. In particular, disclosed are neuromedin U receptor agonists that comprise...
US20100310656 Immunotherapy and prevention of autoimmune hepatitis  
The invention is within the field of immunology and microbiology, more specifically the field of virology and is related to immunotherapy and prophylaxis of hepatitis and autoimmune diseases. The...
US20130323812 IN SITU RESTORATION OF APATITE-BASED CHROMATOGRAPHY RESINS  
Methods and compositions are provided for treatment of an apatite-based resin from which retained solutes have been eluted by an elution buffer that contains an alkali metal salt with solutions of...
US20150158906 Method of Purifying Therapeutic Proteins  
The present invention relates generally to a method of reducing the level of at least one protein selected from the group consisting of plasminogen, tissue plasminogen activator and other...
US20110171285 Design of Fibrinogen and Fibrinogen Derived Products with Reduced Bacterial Binding by Using Modified Sequences of Fibrinogen Chains  
The present invention describes the design and development of new fibrinogen and fibrinogen derived products with significantly reduced binding to bacteria while retaining normal physiological...
US20140206844 METHODS FOR ISOLATING BLOOD PRODUCTS FROM AN INTER-ALPHA INHIBITOR PROTEIN-DEPLETED BLOOD PRODUCT MATERIAL  
Described is a method for isolating multiple blood products from a single starting material. Isolation of multiple blood products from a single starting material maximizes the efficiency of blood...
US20130303731 MANUFACTURE OF FACTOR H (FH) AND FH-DERIVATIVES FROM PLASMA  
The present invention provides compositions and pharmaceutical formulations of Factor H derived from plasma. Also provided are methods for the manufacture of the Factor H compositions and...
US20130102537 MANUFACTURE OF FACTOR H (FH) AND FH-DERIVATIVES FROM PLASMA  
The present invention provides compositions and pharmaceutical formulations of Factor H derived from plasma. Also provided are methods for the manufacture of the Factor H compositions and...
US20130165382 CROSSLINKING OF PROTEINS AND OTHER ENTITIES VIA CONJUGATES OF ALPHA-HALOACETOPHENONES, BENZYL HALIDES, QUINONES, AND THEIR DERIVATIVES  
The present invention relates to the formation of conjugates (e.g., protein-protein dimers) using a-halo-acetophenones, benzylic halides, quinones, and related compounds as a conjugating system....
US20120309936 REDUCING THE IMMUNOGENICITY OF FUSION PROTEINS  
Disclosed are compositions and methods for producing fusion proteins with reduced immunogenicity. Fusion proteins of the invention include a junction region having an amino acid change that...
US20100316702 COMPOSITIONS AND METHODS FOR REGULATING ERYTHROPOEITIN EXPRESSION AND AMELIORATING ANEMIA AND STIMULATING ERYTHROPOIESIS  
The invention provides compositions (e.g., pharmaceuticals, formulations) and methods for ameliorating (e.g., preventing or treating) an anemia and/or stimulating erythropoiesis and/or EPO...
US20140011740 MODIFIED ANIMAL ERYTHROPOIETIN POLYPEPTIDES AND THEIR USES  
Modified animal erythropoietin polypeptides and uses thereof are provided.
US20120258071 Compositions and Methods of Use for MGD-CSF in Disease Treatment  
Disclosed is a newly identified secreted molecule, identified herein as “monocyte, granulocyte, and dendritic cell colony stimulating factor” (MGD-CSF), the polypeptide sequence, and...
US20140163207 METHOD FOR PURIFYING PEGylated ERYTHROPOIETIN  
Herein is reported a method for the purification of a protein comprising erythropoietin and a single poly (ethylene glycol) residue from reaction by-products or not reacted starting material by a...
US20120197007 METHOD FOR PURIFYING PEGylated ERYTHROPOIETIN  
Herein is reported a method for the purification of a protein comprising erythropoietin and a single poly(ethylene glycol) residue from reaction by-products or not reacted starting material by a...
US20110136137 SERUM PROTEOMIC FOR FINDING DIAGNOSTIC MARKERS AND FOR MONITORING THERAPEUTICAL INTERVENTION IN TREATMENT OF HEPATOCELLULAR CARCINOMA  
The invention is directed to biomarkers for determining the EGFR kinase activity in a subject, and the use thereof for predicting and monitoring therapeutic intervention in cancer patients. Areas...
US20120322730 METHODS AND COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF ANEMIA  
Methods for increasing and maintaining hematocrit in a mammal comprising administering a hyperglycosylated analog of erythropoietin are disclosed. An analog may be administered less frequently...
US20110275564 ERYTHROPOIETIN  
This disclosure relates to erythropoietin (EPO) fusion polypeptides; nucleic acid molecules encoding said polypeptides and methods of treatment that use said polypeptides.

Matches 1 - 50 out of 169 1 2 3 4 >