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US20120201857 |
Transdermal delivery system for therapeutics
The present invention provides a method and product for transdermal delivery of therapeutics, including neurotoxins and methods for use thereof. The method and system comprises pharmaceutical... |
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US20150071879 |
Stabilization of Aqueous Compositions of Proteins with Displacement Buffers
An aqueous composition having increased protein stability is obtained by: a. determining a pH at which the protein has stability at the desired temperature; b. adding to the composition at least... |
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US20110190201 |
Method, device, and kit for maintaining physiological levels of steroid hormone in a subject
A method, device, or kit is provided which maintain a substantially physiological cyclic pre-menopausal level of one or more steroid hormones in a mammalian subject in need thereof. The method,... |
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US20140024590 |
KRAS-Variant And Endometriosis
The invention provides methods for predicting an increased risk or probability of developing endometriosis in a patient based upon the patient's KRAS variant status. |
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US20140010859 |
BARLEY PROTEIN MICROCAPSULES
The invention is directed to microcapsules, pharmaceutical or nutraceutical compositions comprising same, and methods for preparing and using same for delivery of nanoparticle coated emulsions... |
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US20120244222 |
OSMOTIC MEDIATED RELEASE SYNTHETIC NANOCARRIERS
This invention relates, at least in part, to osmotic mediated release barrier-free synthetic nanocarriers and methods of production and use. |
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US20130259839 |
GENE EXPRESSION SIGNATURE FOR CLASSIFICATION OF TISSUE OF ORIGIN OF TUMOR SAMPLES
The present invention provides a process for classification of cancers and tissues of origin through the analysis of the expression patterns of specific microRNAs and nucleic acid molecules... |
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US20130136700 |
POLY-HAPTEN WITH TOPICAL HORMONE ALOPECIA HAIR REGROWTH SYSTEM
A hair regrowth system consisting of sensitization, growth, and maintenance kits for alopecia areata and related alopecia balding conditions. Graduated doses of specific engineered and or... |
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US20140170064 |
METHODS AND COMPOSITIONS FOR RADIOHALOGEN PROTEIN LABELING
Methods and compositions are provided for labeling proteins with radiohalogen-label reagents. Radiohalogen-labeled proteins may be used for imaging studies, as therapeutics and in diagnostic... |
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US20110171325 |
Systems and Methods for Treating Pain Using Brain Stimulation
The invention comprises systems and methods for treating nociceptive pain including at least one force-regulatable device in mechanical, electrical, or chemical communication with at least one... |
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US20110223162 |
TARGETING PAX2 FOR THE TREATMENT OF BREAST CANCER
The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of... |
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US20140322237 |
NEURODEGENERATIVE DISEASES AND METHODS OF MODELING
Disclosed are embryonic stem cells and motor neurons derived from mice carrying transgenic alleles of the normal or mutant human SOD1 gene. Also disclosed are in vitro systems employing such SOD1... |
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US20140286914 |
PROTEIN THERAPY FOR TREATMENT OF EYE DISEASES
The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess... |
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US20130143814 |
Protein Therapy for Treatment of Eye Diseases
The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess... |
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US20140322341 |
NOVEL HEMOSTATIC PATCH AND USES THEREOF
Disclosed herein is a novel hemostatic patch that may be used to control and/or arrest bleeding in patients. The patch offers an effective but also minimally invasive way to control and/or arrest... |
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US20110305760 |
TISSUE REGENERATION SYSTEM
A system for growing tissue based upon layers of an inorganic extracellular matrix, wherein each layer of the inorganic matrix is designed to dissolve at a separate rate and result in sequential... |
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US20110003745 |
GRANULATE-MATRIX
Composition comprising a granulate selected from the group consisting of autogenous bone material, bone/bone like material from natural sources, synthetic materials and mixtures thereof and a... |
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US20120114676 |
METHODS OF TREATING CANCER WITH PHENFORMIN
Methods of using phenformin to treat certain types of cancers are described. |
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US20140148389 |
METHODS FOR ACCELERATING WOUND HEALING BY ADMINISTRATION OF ADIPOKINES
The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. |
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US20120148658 |
SOLID DRESSING FOR TREATING WOUNDED TISSUE
Disclosed are solid dressings for treated wounded tissue in mammalian patients, such as a human, comprising a haemostatic layer consisting essentially of fibrinogen and a fibrinogen activator,... |
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US20150087718 |
COMPOSITIONS AND METHODS RELATING TO DENND1A VARIANT 2 AND POLYCYSTIC OVARY SYNDROME
Provided are compositions and methods for use in polycystic ovary syndrome diagnosis (PCOS). The method involves a sample from a subject for a DENND1A Variant 2 mRNA or DENND1 A Variant 2 protein... |
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US20110039775 |
THYROID STIMULATING HORMONE FUSION PROTEINS
We disclose TSH fusion proteins comprising TSHα and/or TSH β and methods to treat diseases that would benefit from administration of TSH agonists and antagonists. |
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US20120093802 |
BIOACTIVE COMPOSITION INCLUDING STABILIZED PROTEIN AND PROCESS FOR PRODUCING THE SAME
A bioactive composition includes a porous hydrogel matrix. At least one protein is immobilized in the porous hydrogel matrix forming a hydrogel protein composite that is stable in an organic... |
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US20110033461 |
Combination Therapy for the Treatment of Cancer
Compositions which act synergistically to inhibit the growth of cancer cells and methods of use thereof are disclosed. |
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US20110217281 |
METHODS FOR DIAGNOSIS AND PROGNOSIS OF CANCER
A method for diagnosing an early stage melanoma which includes detecting the expression level of dual specificity phosphatase 1 protein (DUSP1) and a method for determining a prognosis for a... |
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US20120129773 |
METHODS OF TREATING AUTISM AND AUTISM SPECTRUM DISORDERS
The present invention relates to methods of treating a subject diagnosed with autism or an autism spectrum disorder, lowering the level of mercury in a subject determined to contain a high level... |
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US20130029910 |
METHOD OF TREATING PROSTATE CANCER WITH GnRH ANTAGONIST
The invention provides methods and dosing regimens for safely and effectively treating androgen-dependent prostate cancer with a gonadotrophin releasing hormone (GnRH) antagonist without causing a... |
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US20110059159 |
NANOSCALE BOUND BILAYERS, METHODS OF USE AND PRODUCTION
Methods for rapidly obtaining a nanoscale apolipoprotein bound phospholipid bilayer (NABB) associated with at least one membrane protein are provided. Also disclosed are methods for rapidly... |
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US20140243261 |
Method for treating diabetes and fatty liver disese by stimulating cellular metabolism
The present invention is a method of treating various diseases and conditions through administering a substantial caloric load coupled with administration of hormone to stimulate the body to... |
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US20110086800 |
SCREENING METHOD FOR PREDICTING SUSCEPTIBILITY TO BREAST CANCER
A method to aid in identifying a familial or sporadic pattern of risk in at least one individual for developing cancer of a mucosal epithelial tissue, the method comprising screening said at least... |
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US20130084241 |
DEVELOPMENT OF miRNA DIAGNOSTICS TOOLS IN BLADDER CANCER
The present invention includes methods and compositions related to diagnosis of bladder cancer, including the presence of bladder cancer and/or the type or stage of bladder cancer. In specific... |
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US20110014153 |
REINFORCED TISSUE GRAFT
A biocompatible tissue graft is provided. The tissue graft includes an extracellular matrix patch and a means for reinforcing the patch. |
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US20120329713 |
METHOD FOR DETERMINING LIKELIHOOD OF CLINICAL RECURRENCE OR CLINICALLY STABLE DISEASE OF PROSTATE CANCER AFTER RADICAL PROSTATECTOMY
This invention describes compositions and methods for use in PSA assays having low functional sensitivity which are useful, for example, in the detection of early stage recurrence of prostate... |
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US20100297105 |
ADMINISTERING ANTISENSE OLIGONUCLEOTIDES COMPLEMENTARY TO HUMAN APOLIPOPROTEIN B
Methods for long-term lowering of lipid levels in human subjects and for the treatment of conditions associated with elevated LDL-cholesterol and elevated ApoB are provided. |
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US20150164994 |
SYSTEMS AND METHODS FOR ANGIOGENIC TREATMENT IN WOUND HEALING
The invention relates to systems and methods for the diagnosis, amelioration, and treatment of ischemic tissues in patients caused by and/or resulting from diminished microvascular blood flow.... |
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US20100292791 |
Fully synthetic implantable multi-phased scaffold
An implantable device is provided for soft-tissue or soft tissue-to-bone repair, fixation, augmentation, or replacement that includes a biomimetic and biodegradable nanofiber scaffold. Also... |
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US20120171256 |
ELECTROSPUN SILK MATERIAL SYSTEMS FOR WOUND HEALING
The present invention relates to the processes of preparing silkfibroin/polyethylene oxide blended materials, and the resulting materials thereof, which are suitable for biomedical applications... |
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US20110110934 |
TREATMENT OF UVEITIS
The present invention relates generally to the use of antagonists of G-CSF, and/or its receptor (G-CSFR) in the treatment of uveitis. The present invention contemplates, therefore, the inhibition... |
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US20120058940 |
AZINONE-SUBSTITUTED AZAPOLYCYCLE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF
Novel MCH-1 receptor antagonists are disclosed. These compounds are used in the treatment of various disorders, including obesity, anxiety, depression, non-alcoholic fatty liver disease, and... |
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US20110003738 |
AZINONE-SUBSTITUTED AZAPOLYCYCLE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF
Novel MCH-1 receptor antagonists are disclosed. These compounds are used in the treatment of various disorders, including obesity, anxiety, depression, non-alcoholic fatty liver disease, and... |
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US20140024588 |
METHOD FOR INDUCING SUSTAINED IMMUNE RESPONSE
A method for promoting a sustained increased level of T-cell production in immunocompromised subjects in which method enkephalin peptides are administered according to an intermittent dose... |
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US20140073562 |
NASAL DELIVERY
A nasal delivery device for and method of delivering a substance, preferably comprising oxytocin, non-peptide agonists thereof and antagonists thereof, preferably as one of a liquid, as a... |
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US20110135596 |
FUSION PROTEIN COMPRISING UBIQUITIN OR UBIQUITIN-LIKE PROTEIN, MEMBRANE TRANSLOCATION SEQUENCE AND BIOLOGICALLY ACTIVE MOLECULE AND USE THEREOF
A transmembrane fusion protein including ubiquitin or a ubiquitin-like protein, a membrane translocation sequence linked to the C-terminus of the ubiquitin or ubiquitin-like protein, and a... |
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US20150045295 |
DRY POWDER INHALER AND SYSTEM FOR DRUG DELIVERY
A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided. The dry powder inhaler can be provided with or without a unit dose cartridge for using with... |
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US20120231065 |
METHODS OF TREATING NEUROLOGICAL CONDITIONS WITH HEMATOPOEITIC GROWTH FACTORS
The present invention relates to a method of treating a neurological condition in a mammal by administering at least one hematopoietic growth factor. |
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US20120244216 |
COATED PHARMACEUTICAL CAPSULE DOSAGE FORM
Pharmaceutical compositions in unit dose form comprising a hard or soft capsule containing a fill consisting of one or more inert ingredients, and one or more coatings on the capsule, wherein at... |
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US20140199262 |
METHOD FOR MANUFACTURING PROTEIN DRUG
The present invention provides a method for manufacturing a virus-free protein drug, comprising (a) a filtration step of filtering a virus-containing protein solution through a small-pore size... |
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US20100310583 |
LET-7 MICRORNA AND MIMETICS THEREOF AS THERAPEUTICS FOR CANCER
The present invention relates to methods to treat or prevent cancers in a subject, in particular the present invention relates to a method of treating and/or preventing cancer comprising targeting... |
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US20110190688 |
Permeant Delivery System and Methods for Use Thereof
Disclosed are a patch, system, and method for delivery of a permeant composition into a subject via at least one formed pathway through a biological membrane of the subject. The patch comprises a... |
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US20120134925 |
Application and Uses of PRG4 and Therapeutic Modulation Thereof
The present invention relates to the uses of the protein PRG4 and therapeutic modulation thereof. In particular, the present invention relates compositions and methods utilizing PRG4 and... |