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US20130189321 Parental Composition Comprising Microsperes with a Diameter between 10 and 20 Microns  
The present invention relates to pharmaceutical formulations suitable for targeting particular tissue and/or organ(s) with a formulated active ingredient, for example when administered upstream of...
US20130230485 Methods for Treating Patients Undergoing Multi-Cycle Chemotherapy  
The present invention provides methods for treating a patient undergoing multi-cycle chemotherapy that provides significantly improved platelet counts in the patients, and facilitates retention of...
US20060171899 Water-stabilized aerosol formulation system and method of making  
The invention relates to an aerosol formulation system comprising a primary package system and an aerosol formulation therein wherein the aerosol formulation comprises insulin, a propellant and an...
US20120003181 Novel Retinoid Inducible Factor and Uses Thereof  
The present invention describes a novel retinoid-responsive nucleic acid, and a novel protein. Further, the invention describes the use of such a nucleic acid or protein in various diseases, and...
US20140274896 Transient Protection of Hematopoietic Stem and Progenitor Cells Against Ionizing Radiation  
This invention is in the area of improved compounds and methods for transiently protecting healthy cells, and in particular hematopoietic stem and progenitor cells (HSPC), from the damage...
US20150216933 HEMATOPOIETIC STEM CELL GROWTH FACTOR  
The present invention relates, in general, to stem cells and, in particular, to a hematopoietic stem cell (HSC) growth factor and to methods of using same.
US20110293574 Hematopoietic stem cell growth factor  
The present invention relates, in general, to stem cells and, in particular, to a hematopoietic stem cell (HSC) growth factor and to methods of using same.
US20150250775 METHODS OF USING (+)-1,4-DIHYDRO-7-[(3S,4S)-3-METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID FOR TREATMENT OF ANTECEDENT HEMATOLOGIC DISORDERS  
Methods of treating, preventing or managing antecedent hematologic disorders, such as myelodysplastic syndrome, including chronic myelomonocytic leukemia are disclosed. The methods encompass the...
US20080051332 METHOD OF MODULATING HEMATOPOIETIC STEM CELLS AND TREATING HEMATOLOGIC DISEASES USING INTRANASAL PARATHYROID HORMONE  
A method for modulating hematopoietic stem cells and treating a hematologic disease in a mammal comprising administering intranasally a therapeutically effective amount of a PTH formulation. The...
US20140363394 FORMULATION HAVING MOBILIZING ACTIVITY  
The present innovation relates to a novel formulation capable of increasing the amount of stem cells and progenitor cells in circulation in the peripheral blood of a mammal; the formulation is...
US20060264365 Treatment of brain tissue damage  
Methods of treating brain tissue damage, increasing the expression level of a neuraltrophic factor in a cell, and enhancing angiogenesis in a tissue.
US20080182791 Medicament for Improving Prognostic Survival in Therapy of Malignant Tumor  
A medicament for improving prognostic survival in therapy of malignant tumor is provided that may improve prognostic survival in DIC patients where the basal disease is malignant tumor, especially...
US20070155663 Use of chemokine receptor agonists for stem cell transplantation  
A medicament comprising at least one agonist of receptors selected from the group consisting of the CCR3, CCR6 or CCR8 receptor or combinations thereof and a pharmaceutically acceptable carrier.
US20060153797 Tissue material and matrix  
The present invention relates generally to a tissue preparation including tissue cells and extracts thereof useful for promoting or facilitating the growth, development and differentiation of...
US20060035829 Chemokine combinations to mobilize progenitor/stem cells  
Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 in combination with the CXCR2 chemokine GRO╬▓, including its...
US20060088575 Homeopathic preparations of purified growth factors and purified growth hormones and associated carriers  
A preparation comprising a homeopathic potency of a purified composition, such as insulin-like growth factor, insulin-like growth factor-1 (IGF-1), growth hormone, transforming growth factor...
US20100104580 Altered Immunogenic Landscape in HIV-1 Envelope Proteins  
The present invention provides compositions and methods useful in the prevention and treatment of HIV-1 infection in a host subject. High affinity binding of an allosteric dual antagonist to HIV-1...
US20140348804 AGENT DERIVED FROM TORTOISE SPLEEN STIMULATING MAMMALIAN HEMOPOIESIS  
The present invention relates to a proteinaceous extract derived from tortoise spleen and to a tetrapeptide FTGN, which have stimulatory activity on hematopoietic cells. In particular, this...
US20130129689 AGENT DERIVED FROM TORTOISE SPLEEN STIMULATING MAMMALIAN HEMOPOIESIS  
The present invention relates to a proteinaceous extract derived from tortoise spleen and to a tetrapeptide FTGN, which have stimulatory activity on hematopoietic cells. In particular, this...
US20050014690 Styryl acrylonitrile compounds and their use to promote myelopoiesis  
The invention relates to the use of organic compounds, styryl acrylonitrile compounds to promote myelopoiesis. These compounds thefore may be used to treat a subject suffering from neutropenia and...
US20100041606 Methods of Use of Eggshell Polypeptides  
Identified herein is an active component of chicken eggshells, which is shown ex-vivo studies to have a stimulating effect on bone building cells (osteoblasts). The substance is a polypeptide...
US20050004037 Osteogenic growth oligopeptides as stimulants of hematopoiesis  
The present invention relates to a pharmaceutical composition comprising as an effective ingredient an oligopeptide identical or analogous to the C-terminal portion of OGP, having stimulatory...
US20140227222 CYCLIN DEPENDENT KINASE INHIBITORS AND METHODS OF USE  
The presently disclosed subject matter relates to methods and compositions for protecting healthy cells from damage due to DNA damaging agents. In particular, the presently disclosed subject...
US20100167981 Encapsidation of Heterologous Entities into Virus-Like Particles  
Methods are provided for the utilization of bacterial cell-free extracts in the synthesis of high yields of virus like particles with encapsidated cargo.
US20060024825 METHOD OF PROMOTING EXPANSION OF STEM CELLS  
The present application discloses a method for expanding a population of mammalian cells comprising contacting the cells with angiopoietin 1.
US20060045880 Methods for modulating angiogenesis and apoptosis with apelin compositions  
Novel methods of inhibiting angiogenesis or tumorigenesis or promoting apoptosis with compositions that inhibit the apelin/APJ signaling pathway are provided. Also provided are methods of...
US20130130980 Compositions and Methods for the Intracellular Disruption of VEGF and VEGFR-2 by Intraceptors  
The present invention provides an intraceptor that interacts with and decreases activity of with VEGF and/or a VEGFR for the treatment of angiogenesis-related conditions. The present invention...
US20080051324 Medium-Chain Length Fatty Alcohols as Stimulators of Hematopoiesis  
Medium-chain length fatty alcohols such as octanol, decanol, dodecanol, or analogues thereof can be used as a stimulator of hematopoiesis, hematopoietic stem cell proliferation, and/or...
US20070020703 Use of compositions comprising a soluble form of hla-g in the treatment of blood diseases  
The invention relates to the use of compositions comprising a soluble form of HLA-G in the treatment of blood and circulatory system diseases (anemias and ischaemias).
US20100197581 NATIVE GP41 ASSAY  
The present invention concerns a method for identifying compounds that decrease the ability of Human Immunodeficiency Virus (HIV) to enter previously uninfected cells. More specifically it relates...
US20050181990 Stem cell factor for preventing chemotherapy-induced depletion of blood cells  
The present invention relates to the use of Stem Cell Factor in the protection of multiprogenitor cells and in the prevention of chemotherapy-induced depletion of blood cells.
US20070026512 Atomic structure of the catalytic domain for use in designing and identifying inhibitors of zap-70 kinase  
The present invention relates to the three dimensional structure of ZAP-70 protein tyrosine kinase and describes methods of making a crystal of ZAP-70 and purification of the catalytic domain of...
US20070036747 Pharmaceutical combination useful for stem cell mobilization  
Combined pharmaceutical preparation containing G-CSF and P1GF as the active substances, are useful in the mobilization of blood stem cells in a patient or subject in need thereof.
US20110064735 METHODS FOR TREATING LYMPHOMAS IN CERTAIN PATIENT POPULATIONS AND SCREENING PATIENTS FOR SAID THERAPY  
Methods for predicting a response of a patient having a lymphoma to a therapy regimen of 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-d ione using prognostic factors of a patient's...
US20070166711 Juvenile hemochromatosis gene (hfe2a), expression products and uses thereof  
Polynucleotide and polypeptide sequences for HFE2A, as well as mutations associated with juvenile hemochromatosis, and methods of utilizing these for the screening and identification of agents for...
US20060222625 Therapeutic uses of allogeneic myeloid progenitor cells  
Myeloid function is enhanced by transplantation or infusion of allogeneic myeloid progenitor cells, including CMP, GMP, MEP and MKP cell subsets. Myeloid progenitors ameliorate sequelae of anemia...
US20060188491 Use of nuclear material to therapeutically reprogram differentiated cells  
Methods are provided for therapeutically reprogramming differentiated cells with nuclear extracts from pluripotent stem cells to generate a pluripotent epigenetic state in the differentiated...
US20060172932 Novel erythropoietin receptor agonists  
Disclosed are novel Erythropoietin receptor agonist proteins, DNAs which encode the Erythropoietin receptor agonist proteins, methods of making the Erythropoietin receptor agonist proteins and...
US20070111948 Agent derived from tortoise spleen stimulating mammalian hemopoiesis  
The present invention relates to a proteinaceous extract derived from tortoise spleen and to a tetrapeptide FTGN, which have stimulatory activity on hematopoietic cells. In particular, this...
US20090041760 RETROVIRAL IMMUNOTHERAPY  
The present inventor has noted that at least two populations of immune cells are produced in response to retroviruses which infect mammals. More particularly, the immune system of a mammal...
US20050175724 Composition for modulating a physiological reaction or inducing an immune response  
The present invention relates to a new composition, uses and method for modulating a physiological reaction or inducing an immune response after oral administration to a human or an animal of a...
US20060210532 Means and methods for the recruitment and identification of stem cells  
Described are methods of modulating stem/progenitor cell recruitment involving molecules that agonize the formation of plasmin stimulating the recruitment of stem/progenitor cells, including...
US20070141139 COMPOSITION FOR INTESTINAL DELIVERY  
The present invention relates to a new composition, use and method for oral administration to a human or an animal of a physiologically active agent comprising neutralizing agents to increase pH...
US20070020232 Compositions and methods for cancer immunotherapy  
The invention relates to immunotherapeutic compounds and to methods for stimulating an immune response in a subject individual at risk for developing cancer, diagnosed with a cancer, in treatment...
US20050232896 Cd137 as a proliferation factor for hematopoietic stem cells  
The invention provides the CD137 molecule or a functional analogue thereof, for use in stimulating hematopoiesis. The invention further provides a method of treatment of a disorder characterized...
US20070031331 Treatment of Disorders  
The present invention concerns treatment of polychondritis or mononeuritis multiplex in a mammal with an effective amount of an antibody that binds to CD20, optionally also with another agent that...
US20120164100 TEMPERATURE SENSITIVE HYDROGEL AND BLOCK COPOLYMERS  
The present disclosure provides temperature sensitive hydrogels and block copolymers, processes for the production thereof, and therapeutic and research compositions employing these copolymers.
US20050215473 Prophylactic and therapeutic uses of FGF-20 in radiation protection  
The present invention relates to methods of stimulating stem cell proliferation and engraftment, and methods of preventing and/or treating disorders associated with radiation exposure,...
US20080119385 MODIFIED TWO-COMPONENT GELATION SYSTEMS, METHODS OF USE AND METHODS OF MANUFACTURE  
A bioscaffolding can be formed from a mixture of gel components of different gelation systems. For example, a bioscaffolding can be formed by mixing at least two different components of at least...
US20090264357 NOVEL AGENT THAT INHIBITS ANGIOGENESIS AND METASTASIS TARGETING mTOR SIGNALING PATHWAY  
The present invention relates to a novel function of Msx1 protein for inhibiting tumor angiogenesis and metastasis by targeting mTOR (mammalian target of rapamycin) signaling pathway, and for...

Matches 1 - 50 out of 93 1 2 >