Matches 1 - 50 out of 124 1 2 3 >


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US20120029074 CONTROLLING TRANSGENE EXPRESSION ACROSS THE SKIN  
The invention relates to the use of a skin permeating compound such as phloretin for controlling transgene expression under control of the Pseudomonas putida DOT-T1E-derived bacterial repressor...
US20140045777 METHOD OF INHIBITING PREMATURE AGING OF HUMAN SKIN CAUSED BY EXPOSURE TO INFRARED RADIATION  
A method of inhibiting premature aging of human skin caused by exposure to infrared radiation comprising contacting the skin with a composition containing a therapeutically-effective amount of at...
US20130123368 METHODS OF REDUCING 15-F2T-ISOP LEVELS IN MAMMALS  
Methods of reducing 15-F2t-IsoP levels in mammalian subjects are disclosed herein. In addition, methods of reducing or preventing oxidative stress and treating or preventing related diseases are...
US20140186329 POLYPHENOL ANALOGS TO TREAT ISCHEMIA  
The present invention provides methods of use of polyphenol compounds for treating, preventing, mitigating and delaying ischemia or a condition where ischemia occurs. In one embodiment, the method...
US20140045904 NIACIN FORMULATIONS AND METHODS WITH REDUCED FLUSHING SIDE EFFECT  
Compositions and methods for reducing the flushing effect (cutaneous erythema) of niacin and for treating hyper lipemia and elevated triglycerides, comprising a prenylflavonoid, such as...
US20130287791 MODULATION OF HISTONE H2B MONOUBIQUITINATION AND TREATMENT OF CANCER  
Provided are methods and compositions for treatment of cancer. In particular, these methods and compositions may include an inhibitor of a deubiquitinating enzyme. In certain aspects, these...
US20130309249 MATERIALS AND METHODS FOR THE PROPHYLACTIC TREATMENT OF A PRE-MALIGNANT CONDITION  
Described herein are materials and methods for the prophylactic treatment of a pre-malignant condition, comprising administering a SIRT1 agonist to an individual whose genotype comprises one...
US20120277178 COMPOSITIONS AND METHODS FOR TREATING FRAGILE X PREMUTATION RVGG REPEATS-MEDIATED TOXICITY  
Compositions and methods of treatment or prophylaxis of fragile-X associated disorders are provided, as well as methods of screening compounds and kits to screen a library of compounds.
US20150209307 COMPOSITIONS AND METHODS FOR TREATING MOOD DISORDERS OR SKIN DISEASE OR DAMAGE  
Methods for the treatment of mood disorders and/or skin disease or damage (eczema, atopic dermatitis, or wrinkles, for example) can comprise administering an extracted prenylflavonoid to a subject...
US20140179799 SMALL MOLECULE MODULATORS OF MICRORNA-34A  
The present invention provides methods for identifying compounds that act as miR-34a modulators. The present invention also provides miR-34a modulators and compositions containing the modulators....
US20150045423 COMPOUNDS FOR THE PREVENTION AND/OR TREATMENT OF OSTEOARTHROSIS  
The present invention relates to new compounds which are inter alia derivable from hops for use in the treatment of (for treating)/prevention or healing of a disease which is associated with an...
US20130137761 NEW COMPOUNDS FOR THE PREVENTION AND/OR TREATMENT OF OSTEOARTHROSIS  
The present invention relates to new compounds which are inter alia derivable from hops for use in the treatment of (for treating)/prevention or healing of a disease which is associated with an...
US20140171503 NUCLEAR RECEPTOR MODULATORS AND THEIR USE FOR THE TREATMENT AND PREVENTION OF CANCER  
Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R1 to R5 and X1 to X5 are as...
US20130064913 ANTI-INFLAMMATORY BOTANICAL PRODUCTS FOR THE TREATMENT OF METABOLIC SYNDROME AND DIABETES  
Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions, kits, and methods are additionally disclosed for means to...
US20110082176 Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases  
The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for...
US20110104305 COMPOUNDS AND METHODS FOR THIOL-CONTAINING COMPOUND EFFLUX AND CANCER TREATMENT  
Methods for therapy of cystic fibrosis and other conditions such as cancer are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a...
US20140336258 ANTI-VIRULENCE COMPOSITIONS AND METHODS  
A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the...
US20110218226 ANTI-VIRULENCE COMPOSITIONS AND METHODS  
A method of reducing the virulence of a bacterium that expresses accessory gene regulator A (AgrA) includes administering to the bacterium an amount of AgrA antagonist effective to inhibit the...
US20050158350 Use of licochalcone a or of an extract of radix glycyrrhizae inflatae that contains licochalcone a against postinflammatory hyperpigmentation  
Use of licochalcone A or an extract of radix glycyrrhizae inflatae containing licochalcone A in cosmetic or dermatological preparations for the treatment and prophylaxis of the symptoms of...
US20120136067 OIL/WATER ACTIVE INGREDIENT EMULSION CONTAINING UV FILTER  
A cosmetic oil/water emulsion comprising a) 2-ethylhexyl-2-cyano-3,3-diphenylacrylate (INCI: Octocrylene), b) 4-(tert.-butyl)-4′-methoxydibenzoyl methane (INCI: Butylmethoxydibenzoyl methane), c)...
US20120183630 Compositions and methods for stimulating wound healing  
The present invention realtes to compositions and methods to improve the microenvironments in and around the wound in an effort to enhance healing. Specifically, the present invention comprises...
US20130041023 Composition for Preventing or Treating Rotavirus Infection Comprising Licorice Extract  
The present invention relates to a composition for preventing or treating rotavirus infection, comprising a licorice extract, fractions thereof or compounds separated therefrom. The licorice...
US20050222250 Curcumin for the prevention and/or treatment of tissue damage  
A combination of curcumin, an antioxidant, especially α-tocopherol, and at least one edible oil, especially sunflower oil, is useful in the prevention and/or treatment of tissue damage caused by...
US20090209654 Prenylflavonoid Formulations  
Methods and formulations for increasing the water solubility and/or bioavailability of prenylfiavonoids are disclosed. The formulations may be employed to treat a disease states, including cancer.
US20130212715 Biomarkers for Hematologic Malignacies  
It has been discovered that STAT5 phosphorylation and CD150 are effective biomarkers for detecting, diagnosing, and monitoring hematological malignancies, including for example lymphomas....
US20110111014 METHODS AND COMPOSITIONS FOR TREATMENT OF NEUROLOGICAL DISORDERS  
Methods and compositions are provided for preventing and treating neurological disorders, in particular Parkinson's disease.
US20150065427 MODULATION OF OSTEOCLAST DIFFERENTIATION  
Provided are methods for treating a pathological condition associated with unbalanced osteoclast differentiation by providing an AQP-9 modulator. The modulator can be an AQP-9 inhibitor or an...
US20050147620 Cinnamon formulation for reducing cholesterol and/or glucose levels  
A formulation comprising cinnamon and an active compound such as creatine, a statin drug, niacin, lipoic acid and/or Red Yeast Rice is disclosed. The cinnamon aids in moving the active compound...
US20060154980 IMPROVED COX-2 INHIBITORY COMPOSITIONS AND THERAPEUTIC REGIMEN  
This invention provides improved COX-2 inhibitory compositions comprising a combination of a selective inhibitor of COX-2 and a prostacyclin promoter, especially an antioxidant of the type known...
US20140194474 COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF  
Disclosed are a composition for preventing and treating atherosclerosis which includes chalcone compound. In particular, the chalcone compound bound with 2-hydroxyl in ring A and 4′-methyoxy in...
US20130040996 COMPOSITION FOR TREATING ATHEROSCLEROSIS AND A PREPARATION METHOD THEREOF  
Disclosed are a composition for preventing and treating atherosclerosis which includes chalcone compound. In particular, the chalcone compound bound with 2-hydroxyl in ring A and 4′-methyoxy in...
US20120322717 Compounds and assays for controlling Wnt activity  
The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a...
US20100298200 Compounds and assays for controlling Wnt activity  
The present invention relates to the field of therapeutic methods to screen for compounds on the basis of their ability to influence Wnt activity. The screening process is applied to both a...
US20090202464 Fragrance Compounds  
A method of providing a fragrant odour to an application, comprising the addition thereto of at least one compound of the formula (I) wherein X and Y are independently selected from the group...
US20110152263 COMPOSITION AND METHOD FOR INHIBITING NOROVIRUS INFECTION  
A composition for use in inhibiting the binding of a Norovirus to the histo-blood group antigen on the surface of epithelia. The composition contains a therapeutically effective amount of a...
US20130149393 MEDICAL COMPOSITIONS CONTAINING LIQUORICE EXTRACTS WITH SYNERGISTIC EFFECT  
The invention provides drug compositions with synergistic effects, which includes alcohol-soluble and water-insoluble liquorices extracts and at least one kind of anti-tumor or...
US20150141522 ACTIVE SUBSTANCE COMBINATION OF LICOCHALCONE A AND PHENOXYETHANOL  
Disclosed is a method for the treatment or prophylaxis of an inflammatory skin condition with cosmetic or pharmaceutical preparation which comprises licochalcone A and phenoxyethanol.
US20120040916 MOLECULAR INHIBITORS OF THE WNT/BETA-CATENIN PATHWAY  
The present invention is directed toward a method of treating a subject for a condition mediated by the Wnt/β-catenin pathway by selecting a subject with a condition mediated by the Wnt/β-catenin...
US20090131340 USE OF FLAVONOIDS AS IMMUNOMODULATING OR IMMUNO-PROTECTIVE AGENTS IN COSMETIC AND DERMATOLOGICAL PREPARATIONS  
A method of treating or prophylactically treating immunosuppression or allergic and inflammatory symptoms of skin caused by UVB radiation which comprises applying to the skin a cosmetic or...
US20120238501 Modulation Of Osteoclast Differentiation  
The present invention concerns the use of an aquaprin-9 (AQP-9) modulator for the preparation of a pharmaceutical composition for treating or preventing a pathological condition associates with...
US20130253068 Cosmetic or Dermatological Preparations Containing Licochalcone A or an Extract of Radix Glycyrrhizae inflatae, Containing Licochalcone A  
Disclosed are cosmetic or dermatological preparations for the treatment or alleviation of erythema which comprise an aqueous extract of Radix Glycyrrhizae inflatae or licochalcone A and optionally...
US20100137449 SUBSTITUTED 1,3-CYCLOPENTADIONE MULTI-TARGET PROTEIN KINASE MODULATORS OF CANCER, ANGIOGENESIS AND THE INFLAMMATORY PATHWAYS ASSOCIATED THEREWITH  
Compounds and methods for multi-targeted protein kinase modulation for angiogenesis, cancer treatment or the inflammatory pathways associated with those conditions are disclosed. The compounds and...
US20080188549 Composition for Preventing and/or Treating Metabolic Syndrome and Insulin Resistance Syndrome  
The present invention has its object to provide a specific compound derived from a naturally occurring substance, and a composition for the prevention and/or treatment of metabolic syndrome and...
US20050118287 Use of a vanilloid as an anti-snoring element  
The invention relates to the use of a vallinoid to diminish, suppress or prevent snoring and in the production of a medicament for the treatment of sleep apnoea. Preferably, the vallinoid is...
US20090232853 TREATMENT OF LAMINITIS  
The present invention provides a composition comprising one or more of a matrix metalloprotease inhibitor, a de-carboxylase inhibitor, a fructanase enzyme and/or a flavonoid for use in the...
US20130338120 Aspirin Derivatives and Uses Thereof  
The present invention provides novel aspirin derivatives useful for preventing and/or treating cancer. The novel compounds of this invention may be particularly useful for the prevention and/or...
US20140088052 CHALCONE DERIVATIVES AS NRF2 ACTIVATORS  
Compounds and methods for treating or preventing a disease, disorder or condition associated with an Nrf2-regulated pathway, including those associated with an autoimmune disease, comorbidity...
US20110144195 METHODS FOR SYNTHESIZING GLYCINOLS, GLYCEOLLINS I AND II, COMPOSITIONS OF SELECTED INTERMEDIATES, AND THERAPEUTIC USES THEREOF  
Two distinct methods are disclosed and claimed for synthesizing glyceollin I plus glyceollin II as a mixture and as their pure forms. Stereochemical isomers and various synthetic intermediates are...
US20120251464 CHALCONES AS ENHANCER OF ANTIMICROBIAL AGENTS  
Compounds are described that are effective in enhancing the efficacy of antimicrobial agents. Also described are methods of using such compounds and compositions that include such compounds. The...
US20110263721 ARYL DI-SUBSTITUTED PROPENONE COMPOUNDS  
Compounds of formula (I): wherein R1 and R4 are OR7, R2 and R3 are H or OR7, with the proviso that when R2 is OR7 then R3 is H, and when R3 is OR7 then R2 is H; R5 and R6 are independently H, OH,...

Matches 1 - 50 out of 124 1 2 3 >