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US20120269901 |
Methods and Compounds Useful to Induce Apoptosis in Cancer Cells
The present invention provides a method for treating cancer in a mammal comprising contacting the cancer cells with a compound which is a apogossypol, derivative. |
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US20120264692 |
GENETIC POLYMORPHISMS ASSOCIATED WITH VENOUS THROMBOSIS, METHODS OF DETECTION AND USES THEREOF
The present invention is based on the discovery of genetic polymorphisms that are associated with venous thrombosis. In particular, the present invention relates to nucleic acid molecules... |
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US20100130618 |
TREATMENT OF HUMAN DISEASE CONDITIONS AND DISORDERS USING VITAMIN K ANALOGUES AND DERIVATIVES
The present invention is related to the therapeutic uses of vitamin K, its analogues and derivatives in a diverse array of disease conditions. Vitamin K improves blood perfusion and ameliorates... |
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US20130137640 |
Skin Collagen Enhancing Agent
A composition includes a food ingredient or nutrient with safety and experience having been eaten for a long time and that shows a collagen enhancing activity. The food ingredient or nutrient of... |
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US20120308658 |
METHODS AND COMPOSITIONS TO TREAT HEMORRHAGIC CONDITIONS OF THE BRAIN
The described invention provides a nonhuman animal model system for hemorrhagic brain conditions, methods for evaluating a substance for treating the hemorrhagic brain condition in a mammal,... |
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US20120208893 |
NUTRITIONAL COMPOSITIONS FOR MODULATING INFLAMMATION INCLUDING EXOGENOUS VITAMIN K2
Nutritional compositions and methods of making and using the nutritional compositions are provided. In a general embodiment, the present disclosure provides a nutritional composition including... |
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US20080119537 |
5-Aryl indan-1 one and analogs useful as progesterone receptor modulators
Compounds of formula I or II and pharmaceutical compositions and kits containing these compounds are provided. Also provided are methods of inducing contraception, providing hormone replacement... |
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US20120130147 |
METHODS FOR THE TREATMENT OF TUMORS WITH INDANE COMPOUNDS
Compounds of the formula (I), in which R1, R2, R3, R4, and q have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumours. |
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US20160081975 |
SOFT GEL COMPOSITIONS AND PRE-GEL CONCENTRATES
Provided are compositions and methods for producing non-aqueous capsule compositions that contain additives such as essential fatty acids, including omega-3 fatty acids, omega-6 fatty acids,... |
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US20120277180 |
Cofactors and Methods for Use for Individuals
Provided herein are methods and systems for identifying one or more cofactors such as vitamins for individuals based on the genetic makeup of the individual by detecting the presence or absence of... |
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US20090118377 |
APOGOSSYPOLONE AND THE USES THEREOF
The invention relates to the compound apogossypolone and salts and prodrugs thereof. Apogossypolone functions as an inhibitor of Bcl-2 family proteins. The invention also relates to the use of... |
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US20090175869 |
Pulsatile Dosing of Gossypol for Treatment of Disease
This invention relates to pulsatile dose administration of gossypol, a gossypol-related compound or pharmaceutical compositions thereof for treating diseases, disorders and conditions responsive... |
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US20140031432 |
TREATMENT OF MITOCHONDRIAL DISEASES WITH VITAMIN K
Methods of treating, preventing or suppressing symptoms associated with mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), dominant optic... |
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US20090186900 |
COMPOUND
There is provided a compound of Formula I wherein the various symbols are as defined in the description, and a method of manufacturing a medicament for use in the therapy of a condition or disease... |
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US20150164825 |
METHOD FOR INCREASING BONE DENSITY AND/OR REDUCING ANY OSTEOCHONDRAL DEFECTS IN AN ANIMAL AND A COMPOSITION INCLUDING VITAMIN K
There is disclosed herein a method of increasing bone density, maintaining bone density and/or inhibiting loss of bone density and/or reducing osteochondral defects in an animal comprising... |
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US20150328204 |
METHODS FOR TREATMENT OF MELANOMA
Embodiments of the present invention are directed to methods for treatment of melanoma using an inhibitor of dihydroorotate dehydrogenase (DHODH) and to combination therapies that involve... |
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US20120207707 |
METHODS AND COMPOSITIONS FOR ENHANCING POLYPEPTIDE PRODUCTION
Methods of increasing production, stability or activity of a target polypeptide are provided herein. The method includes increasing the level of an antioxidant in a cell comprising a... |
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US20150272924 |
VITAMIN C, VITAMIN K, A POLYPHENOL, AND COMBINATIONS THEREOF FOR WOUND HEALING
Provided herein is a method of promoting wound healing in a subject, comprising administering to the subject vitamin C, vitamin K, a polyphenol, or a combination thereof. Also provided herein is a... |
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US20090285865 |
Palatable, solid oral formulations for male chemical sterilization
Palatable, solid oral formulations or compositions include at least one bioactive agent capable of chemical sterilization of human and animal males. Depending on the targeted species, the... |
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US20130281544 |
HEPATOPROTECTANT ACTIVITY OF GARCINOL
The present invention discloses the hepatoprotective potential of garcinol. |
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US20050054735 |
6-Methoxy-2-naphthylacetic acid prodrugs
The present invention provides therapeutically effective amounts of 6MNA prodrugs. The pharmaceutical composition comprises wherein R is H or COR′, wherein R′ is selected from the group consisting... |
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US20120259007 |
ANTICOAGULANT COMPOUNDS AND THEIR USE
According to the invention there is provided a compound of formula (I): wherein R1, R2, R3 and n have meanings given in the description, or a pharmaceutically acceptable solvate, salt or prodrug... |
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US20120322889 |
PLANT PROTECTION AGENT
The invention relates to the use of a compound according to formula (A) or formula (B), where R1, R4 and R5 are H, a glycoside, or an ester independently of each other, as a plant protection... |
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US20080220094 |
Compositions and methods for the treatment and/or prevention of osteoporosis
The invention of this application relates to compositions and methods for the treatment and/or prevention of osteoporosis; improving and/or enhancing bone formation; and prevention and/or reducing... |
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US20130225517 |
Therapeutic Compounds
The invention provides compounds of formula I: or salts thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I and therapeutic... |
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US20130090355 |
CHEMICAL AGENTS FOR THE PREVENTION OF INHIBITION OR TUMOR METASTASIS
The present invention provides methods of preventing or inhibiting tumor metastasis in a subject by administering a therapeutically effective amount of (1) a compound from a group of enumerated... |
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US20070225237 |
Methods for the prevention and/or the treatment of glutamate cytotoxicity
The present invention relates to the use of beta-naphthoquinone derivatives, and salts thereof, for the prevention and /or the treatment of glutamate cytotoxicity. It further relates to the use of... |
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US20070225236 |
Methods for the prevention and/or the treatment of glutamate cytotoxicity
The present invention relates to the use of beta-naphthoquinone derivatives, and salts thereof, for the prevention and/or the treatment of glutamate cytotoxicity. It further relates to the use of... |
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US20100305095 |
Use of HPPD Inhibitors in the Treatment of Depression and/or Withdrawal Symptoms Associated with Addictive Drugs
The present invention relates to, inter alia, the use of a compound capable of inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD) in an animal in the manufacture of a medicament for use in the... |
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US20100015221 |
ORALLY RAPID DISINTEGRATING TABLET PREPARATION COMPRISING FAT-SOLUBLE ACTIVE INGREDIENTS
The present invention provides an orally rapid disintegrating tablet preparation that contains a high dose of a fat-soluble active ingredient, that exhibits excellent disintegration... |
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US20150359757 |
A METHOD FOR IMPROVING THE WELLBEING OF AN ANIMAL USING A COMPOSITION INCLUDING VITAMIN K
There is disclosed herein a method of improving the wellbeing, as herein defined, of an animal comprising administering to an animal an effective amount of a composition containing: vitamin K1,... |
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US20140194530 |
USAGE OF OBLONGIFOLIN C, A NATURAL COMPOUND FROM GARCINIA YUNNANENSIS HU, ON TREATING CANCER AS METASTASIS INHIBITOR AND AUTOPHAGIC FLUX INHIBITOR
Disclosed is a natural compound, Oblongifolin C, isolated from a natural plant comprising Garcinia species such as Garcinia yunnanesis Hu, for its effects of anti-migration and anti-invasion... |
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US20090099250 |
BENZOCYCLOHEPTENE DERIVATIVES AS ESTROGENS HAVING SELECTIVE ACTIVITY
The present invention describes non-steroidal compounds of the general formula (I) in whichA is in which X1 means one or more groups on the phenyl ring and represents independently of one another... |
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US20050222273 |
Treatment of female sexual dysfunction
A treatment for female sexual dysfunction by the provision of at least one dopamine mimetic odorant, the odorant being capable of causing a physiological effect in, or from, the human brain which... |
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US20080171085 |
Novel biphasic delivery system for a pharmaceutical or nutraceutical composition and method of administration
A novel biphasic pharmaceutial or nutraceutical composition delivers both an immediate and a sustained dose of a pharmaceutical or nutraceutical agent in the same unit dose. An oral unit dose of... |
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US20120149780 |
Method of Use of Vitamin K as Energy Enhancer in Diverse Disease States
The invention relates to Vitamin K, its derivatives and combinations to increase the energy levels in diverse disease states and life style disorders, which are characterized by low energy level... |
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US20160095824 |
USE OF VITAMIN K FOR WEIGHT MAINTENANCE AND WEIGHT CONTROL
Vitamin K is effective in counteracting (1) increase of body weight and body mass index (BMI), (2) accumulation of body fat mass and (3) accelerates weight loss during calory restriction or other... |
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US20140228447 |
AGENT FOR INCREASING TESTOSTERONE LEVEL
Provided is a substance which is a safer and more commonly-consumed food ingredient that increase the testosterone level. The testosterone enhancer of the invention comprises vitamin K as an... |
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US20120077869 |
METHOD AND COMPOSITION USING A DUAL SPECIFICITY PROTEIN TYROSINE PHOSPHATASE AS AN ANTIMALARIAL DRUG TARGET
Phosphotyrosine phosphatase (PTP) encoded by PF13_0027 is a desirable drug target for the human malaria parasite Plasmodium falciparum. This PTP is critical for intraerythrocytic parasite... |
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US20140314867 |
VITAMIN K2 MICROSPHERES
A vitamin K2 microsphere. The microsphere includes a poly(lactide-co-glycolide) acid (PLGA) particle, in which the Mw of PLGA is between 1000 and 300000, and the molar ratio between the lactide... |
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US20080200441 |
ESTROGEN RECEPTOR MODULATORS ASSOCIATED PHARMACEUTICAL COMPOSITIONS AND METHODS OF USE
Selective estrogen receptor modulators, as well their related pharmaceutical compositions and methods of use, are provided herein. These estrogen receptor modulators include compounds that... |
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US20140128257 |
PESTICIDAL COMPOSITIONS COMPRISING 4,5-DIHYDROXYINDAN-1-ONE
Provided are pesticidal compositions comprising 4,5-dihydroxyindan-1-one or derivatives thereof for protecting important crops against mites, fungi, and bacteria. The compositions may be... |
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US20130267606 |
USE OF VITAMIN K FOR WEIGHT MAINTENANCE AND WEIGHT CONTROL
Vitamin K is effective in counteracting (1) increase of body weight and body mass index (BMI), (2) accumulation of body fat mass and (3) accelerates weight loss during calory restriction or other... |
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US20080051464 |
Protein phosphatase inhibitors
A method of inhibiting protein tyrosine phosphatase in a subject includes administering to the subject a therapeutically effective amount of at least one benzo-1,4-quinone, phenyl isothiazolone,... |
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US20150166476 |
METHODS FOR TREATING NEURODEGENERATIVE DISEASES ASSOCIATED WITH AGGREGATION OF AMYLOID-BETA
Disclosed herein is a method for prophylaxis or treatment of a neurodegenerative disease associated with aggregation of amyloid-beta (Aβ) in a subject. The method includes the step of,... |
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US20140088185 |
METHOD OF TREATING DIGESTIVE UPSETS BY BUCCAL ADMINISTRATION OF BOTANICAL DERIVATIVES
A buccally administered dosage for assisting with the relief of common digestive complaints where the dosage formed into a hard candy dosage drop, where the dosage is a sugar base infused with a... |
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US20130224286 |
METHODS AND COMPOSITIONS FOR TREATING POX VIRUS INFECTIONS
Human viral infections can cause lesions of the skin and/or mucous membranes. Provided herein are 1,4-naphthoquinone family compounds which are useful in the treatment of these lesions. Further... |
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US20140194499 |
Polyprenylated Benzoylphloroglucinols With Anticancer Activity
Two novel polyprenylated benzoylphloroglucinol derivatives, garciesculentones A and C, are disclosed in the present invention. Garciesculentones A and C exhibit cytotoxicity and/or antimigration... |
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US20070015750 |
Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents
The invention relates to polysubstituted tetrahydronaphthalene derivatives of formula (I), process for their production and their use as anti-inflammatory agents. |
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US20140309186 |
Metabolomics-Based Identification of Disease-Causing Agents
A method, computer-readable medium, and system for identifying one or more metabolites associated with a disease, comprising: comparing gene expression data from diseased cells to gene expression... |