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US20120087994 SYSTEMIC ADMINISTRATION OF NAC AS AN ADJUNCT IN THE TREATMENT OF BIOTERROR EXPOSURES SUCH AS SMALLPOX AND USE IN COMBINATION WITH DHEA FOR THE TREATMENT OF SMALLPOX  
The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or...
US20120021073 SYSTEMIC ADMINISTRATION OF NAC AS AN ADJUNCT IN THE TREATMENT OF BIOTERROR EXPOSURES SUCH AS SMALLPOX AND USE IN COMBINATION WITH DHEA FOR THE TREATMENT OF SMALLPOX  
The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or...
US20120238627 N-ACETYL-L-CYSTEINE FOR THE TREATMENT OF ENDOMETRIOSIS  
The invention relates to a new prescription of NAC in the treatment of endometriosis and of indications associated with endometriosis, in a human or mammalian animal patient. In addition an...
US20110177000 Use of S-Nitrosothiol Signaling to Treat Disordered Control of Breathing  
The present invention is directed to a method of treating disordered control of breathing including the treatment of apnea and hypoventilation associated with congenital or acquired brain stem...
US20140073611 METHODS FOR DRUG SCREEN USING ZEBRAFISH MODEL AND THE COMPOUNDS SCREENED THEREFROM  
The disclosure relates to a platform of using zebrafish in screening candidates for treating and/or preventing myopia and keratoconus disease. The disclosure is mainly based on that Lumican, one...
US20150044200 TREATMENT OF TINNITUS THROUGH MODULATION OF CHLORIDE CO-TRANSPORTER NKCC1 IN THE AUDITORY SYSTEM  
The present invention relates to the treatment or prevention of tinnitus. More precisely, the present invention relates to a compound modulating chloride co-transporter NKCC1 (chloride...
US20140200275 Method for Treating Skin Cancer  
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant...
US20110034519 NUTRITIONAL SUPPLEMENTS  
A process for improving the health of a subject, the process comprising orally administering a composition comprising hydroxytyrosol to the subject to provide the subject with a daily dose of...
US20120238601 TREATMENT OF CANCER  
The present invention provides compositions of matter, kits and methods for their use in the treatment of cancer. In particular, the invention provides compositions and methods for treating cancer...
US20110250286 Micro Particles for Oral Delivery in Animals  
A system for the controlled release of one or more physiologically or pharmacologically active substances, comprising compositions in the form of micro particles or granules, particularly for use...
US20120295977 Organosulfur prodrugs for the prevention and treatment of infectious diseases  
A method for enhancing the overall beneficial immune system response in a host that works in conjunction with the host's natural immune system response to enhance the host's ability to eliminate...
US20120214873 CYSTEINE FOR PHYSIOLOGICAL INJECTION  
This application describes methods of making and using physiological cysteine solutions useful for reversing a neuromuscular blockade caused by a cysteine-reversible neuromuscular blockade agent,...
US20140011879 SERUM MARKERS FOR IDENTIFICATION OF CUTANEOUS SYSTEMIC SCLEROSIS SUBJECTS  
Tools for diagnosis and management of patients suspected of having or having been previously diagnosed with systemic sclerosis are based on the determination one or more of the markers described...
US20140100283 Method to Increase Absorption and Bioavailability of Oral Glutathione  
An improved method for delivery of glutathione, a major intracellular antioxidant, by oral administration of S-acetyl-glutathione (SAG) is provided. The method is designed to raise the circulating...
US20130064884 COMPOSITION AND METHOD FOR TREATING KETOSIS IN COWS  
A method for prophylactic treatment of ketosis in a calving cow, the method including orally administering to the cow within a time period of about 12 hours after calving an effective dose of from...
US20130108709 TREATMENT OF MITOCHONDRIA-RELATED DISEASES AND IMPROVEMENT OF AGE-RELATED METABOLIC DEFICITS  
Pharmaceutical compositions and methods for the treatment of subjects, including humans, who have or are at risk for various disease, disorders and conditions, including, mitochondria-associated...
US20110236508 L-ARGININE-BASED FORMULATION FOR ORAL ABSORPTION  
A formulation comprising large quantities of l-arginine and/or fat plaque dissolving agents which is palatable, stench free, and does not evoke nausea. The formulation is adapted to facilitate the...
US20140235604 COMPOUNDS AND METHODS OF TREATING OCULAR DISORDERS  
A method of treating an ocular disorder in a subject associated with aberrant all-trans-retinal clearance in the retina, the method comprising administering to the subject a therapeutically...
US20130338165 Use of Compounds Elevating Glutathione Levels for the Treatment of Parkinson's Disease  
Methods of treating Parkinson's Disease comprising administering compounds that up-regulate cystine-glutamate exchange (system Xc−) and/or increase glutathione levels in the brain cells. Preferred...
US20140178358 Means and Methods to Diagnose Liver Toxicity using Putrescine as Biomarker  
The present invention concerns means and methods for predicting the risk of a subject to suffer from liver damage. In particular, it pertains to a method for predicting the risk of a subject to...
US20140288177 Increasing Glutathione Levels for Therapy  
The present invention concerns compositions and methods related to utilizing glycine and N-acetylcysteine for a variety of methods, including, for example, reducing deleterious effects of...
US20130245121 INCREASING GLUTATHIONE LEVELS FOR THERAPY  
The present invention concerns compositions and methods related to utilizing glycine and N-acetylcysteine for a variety of methods, including, for example, reducing deleterious effects of...
US20110077303 INCREASING GLUTATHIONE LEVELS FOR THERAPY  
The present invention concerns compositions and methods related to utilizing glycine and N-acetylcysteine for a variety of methods, including, for example, reducing deleterious effects of...
US20090060922 Acetamide Stereoisomer  
The compound of formula (I) is a water-stable, long acting β2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible...
US20130210771 METHODS AND COMPOSITIONS FOR TREATING CANCERS  
This invention provides a combination of antagonists of the hedgehog signaling pathway with a BCR-ABL inhibitor. The combination of the present invention may be used for treating cancers known to...
US20120237570 METHODS AND COMPOSITIONS FOR TREATING DISTRESS DYSFUNCTION AND ENHANCING SAFETY AND EFFICACY OF SPECIFIC MEDICATIONS  
The present invention relates to methods and compositions for reducing distress dysfunction, including emotional and physical distress. The invention entails co-administration of at least one...
US20110046083 ACTIVATORS OF PYRUVATE KINASE M2 AND METHODS OF TREATING DISEASE  
The invention described herein features methods, compositions, and kits for the use of activators of PKM2 for the treatment, prevention, or amelioration of diseases related to PKM2 function,...
US20100233297 SYSTEMIC ADMINISTRATION OF NAC AS AN ADJUNCT IN THE TREATMENT OF TERRORISM EXPOSURES SUCH AS RADIATION AND FOR PROPHYLAXIS  
The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or...
US20110165098 METHODS TO PREVENT CYTOTOXICITY USING N-ACETYL-CYSTEINE  
Compositions and methods to inhibit adverse physiological effects caused by resin-based and resin-containing materials are disclosed. More specifically, the use of N-acetyl-cysteine (NAC) to...
US20110065729 METHODS AND COMPOSITIONS FOR AMELIORATING THE UNDESIRABLE EFFECTS OF CHEMOTHERAPY  
In one aspect, the present invention provides chemoprotectant compositions that each comprise at least two of the chemoprotectants disclosed herein. The chemoprotectant compositions of the...
US20120195984 DIAGNOSIS AND TREATMENT OF THE PRODROMAL SCHIZOPHRENIC STATE  
Described herein are compounds (including medical foods, pharmaceutical compositions, methods of compounding them), methods and systems for the diagnosis and/or treatment of prodromal...
US20120027723 TAURINE OR TAURINE-LIKE SUBSTANCES FOR THE PREVENTION AND TREATMENT OF A DISEASE ASSOCIATED WITH RETINAL GANGLION CELL DEGENERATION  
The present invention relates to taurine or taurine-like substances for the prevention and treatment of a disease associated with retinal ganglion cell degeneration. More particularly the...
US20150247839 CMPF AS A BIOMARKER FOR DIABETES AND ASSOCIATED METHODS  
Provided are methods for identifying or monitoring a subject having, or at risk of developing, impaired glucose homeostasis. Carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF) is shown to be a...
US20120172435 METHODS FOR TREATING ACUTE ACOUSTIC TRAUMA  
The current invention provides methods and compositions for treating sensorineural hearing loss including but not limited to acute acoustic trauma (AAT). The composition 2,4-disulfonyl α-phenyl...
US20140045937 METHODS OF TREATING POLYCYSTIC OVARIAN SYNDROME USING CHLOROGENIC ACID  
The invention provides a method of treating or preventing polycystic ovarian syndrome (PCOS) in a mammal, comprising administering chlorogenic acid in an amount effective to treat or prevent PCOS...
US20140024683 CHLORIDE CHANNEL AND CHLORIDE TRANSPORTER MODULATORS FOR THERAPY IN SMOOTH MUSCLE DISEASES  
The present invention provides, inter alia, methods and pharmaceutical compositions for preventing, treating, or ameliorating the effects of a disease characterized by altered smooth muscle...
US20130143967 Organosulfur compounds for the prevention and treatment of neurodegenerative diseases  
S-allylmercapto-N-acetylcysteine and related compounds are disclosed which can be administered in order to provide protection from the formation of aldehyde-protein adducts, protein carbonylation,...
US20140010901 BLEOMYCIN HYDROLASE PRODUCTION PROMOTOR  
Provided is a novel bleomycin hydrolase production promoter. Provided is a bleomycin hydrolase production promoter, natural moisturizing factor production promoter, and dry skin remedy, comprising...
US20110159017 TRYTOPHAN CATABOLISM IN CANCER TREATMENT AND DIAGNOSIS  
The unexpected expression of tryptophan 2,3-dioxygenase (TDO2) in cancer cells and tumors has been established. Methods for diagnosing cancer based on the expression of TDO2 are provided, as are...
US20130079411 METHOD FOR PREVENTING OR TREATING A DISEASE, DISORDER OR CONDITION INDUCED BY RETINA ISCHEMIA  
The present invention provides a method for preventing or treating a disease, disorder or condition induced by retina ischemia, comprising administering to a subject in need thereof a...
US20140378425 BIOMARKERS FOR DIAGNOSIS OF LUNG DISEASES AND METHODS OF USE THEREOF  
The present disclosure provides methods for diagnosis of interstitial lung diseases (ILDs). The present disclosure provides methods for differential diagnosis of idiopathic pulmonary fibrosis from...
US20120156163 METHODS OF DECREASING SEBUM PRODUCTION IN THE SKIN  
Provided herein are methods of using gaseous nitric oxide and/or at least one nitric oxide source to or decrease sebum production in the skin of a subject. In some embodiments, the nitric oxide...
US20120184493 DERMAL FORMULATIONS OF DP2 RECEPTOR ANTAGONISTS  
Described herein are topical formulations for use in the treatment or prevention of dermatological diseases, disorders, or conditions in a mammal. Topical formulations disclosed herein include a...
US20140073694 CYSTAMINE ANALOGUES FOR THE TREATMENT OF PARKINSON'S DISEASE  
The present invention relates to the use of cystamine analogues for the treatment of Parkinson's disease. The present invention also relates to the use of composition comprising cystamine...
US20140378522 UNIFYING MECHANISM AND METHODS TO PREVENT CANCER AND NEURODEGENERATIVE DISEASES  
The present invention relates to methods for preventing the development of cancer or neurodegenerative diseases by administering N-Acetylcysteine (NAC), melatonin, or a combination thereof. The...
US20130142768 Method for Improving Eye Health  
The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of...
US20130061339 METHOD OF DIAGNOSING TRICHOTILLOMANIA AND SIMILAR DISORDERS IN HUMANS AND RODENTS  
The present disclosure provides a method of diagnosing neurological disorders including for example, impulse control disorders, such as barbering and trichotillomania using biomarkers such as...
US20120270860 METHODS FOR TREATING OR PREVENTING ALCOHOL-RELATED DISORDERS OR CRAVING-RELATED DISORDERS  
The invention provides methods for treating or preventing alcohol-related disorders or craving-related disorders comprising administering an effective amount of N-acetylcysteine or a...
US20140080910 COMPOUNDS FOR THE TREATMENT OF AUTISM IN A BABY CHILD  
The invention relates to a compound which inhibits the importation of chloride into neurons or a compound which improve the outflow of chloride from neurons for use in the treatment of autism in a...
US20130296328 EPIGENETIC PORTRAITS OF HUMAN BREAST CANCERS  
The present invention provides new target gene regions for use in prediction, prognosis, diagnosis and therapy of breast cancer, based on the differential methylation profile of said targets in...