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US20100166874 Technology for Preparation of Macromolecular Microspheres  
Microspheres are produced by contacting an aqueous solution of a protein or other macromolecule with an organic solvent and a counterion, and chilling the solution. The microspheres are useful for...
US20140213547 HYALURONIC ACID-BASED GELS INCLUDING LIDOCAINE  
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic...
US20140147479 METHOD OF SOFT TISSUE AUGMENTATION  
Particles according to the invention are made of a viscoelastic medium, are injectable gel particles, and have a size, when subjected to a physiological salt solution, in the range of from 1 to 5...
US20140079749 COMPOSITIONS AND METHODS FOR IMPROVED SKIN CARE  
Compositions and methods for administering collagen to a human subject have been developed. The collagen-containing lipid vesicles of the invention provide a delivery system for human collagen...
US20140045773 OPHTHALMIC COMPOSITIONS AND METHODS FOR TREATING EYES  
Ophthalmic compositions including compatible solute components and/or polyanionic components are useful in treating eyes, for example, to relieve dry eye syndrome, to protect the eyes against...
US20130244969 Prebiotic Formulations and Methods of Use  
The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and...
US20130197444 REGIMENS FOR INTRA-ARTICULAR VISCOSUPPLEMENTATION  
The invention provides viscosupplementation methods for treating osteoarthritis and joint injury with HA-based viscosupplements, particularly viscosupplements with an intra-articular residence...
US20130183325 MUCOADHESIVE XYLOGLUCAN-CONTAINING FORMULATIONS USEFUL IN MEDICAL DEVICES AND IN PHARMACEUTICAL FORMULATIONS  
Object of the invention are mucoadhesive and controlled release formulations consisting of aqueous solutions containing 0.05% to 5% by weight of a natural purified polymer having xyloglucan...
US20130177612 Prebiotic Formulations and Methods of Use  
The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and...
US20130165407 Prebiotic Formulations and Methods of Use  
The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and...
US20130122068 THREADS OF CROSS-LINKED HYALURONIC ACID AND METHODS OF USE THEREOF  
This disclosure relates generally to threads with improved properties comprising cross-linked hyaluronic acid, optimized methods of making such threads and uses thereof, for example, in aesthetic...
US20130102563 DERMAL FILLER WITH LIDOCAINE  
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic...
US20120177752 NUTRITIONAL COMPOSITIONS INCLUDING BETA-HYDROXY-BETA-METHYLBUTYRATE  
The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients...
US20120177720 MULTI-LAYER WOUND DRESSINGS  
A wound dressing includes one or more layers containing a first anti-microbial agent and optionally at least one of: a chelating agent, a second anti-microbial agent, a zinc-containing agent, a...
US20110046606 Catheter injectable depot compositions and uses thereof  
Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an...
US20110020337 METHODS FOR TREATING CONDITIONS ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION  
In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject...
US20100221319 Compositions and Methods for Improved Skin Care  
Compositions and methods for administering collagen to a human subject have been developed. The collagen-containing lipid vesicles of the invention provide a delivery system for human collagen...
US20100196517 TOPICAL DELIVERY OF A NITRIC OXIDE DONOR TO IMPROVE BODY AND SKIN APPEARANCE  
This invention generally relates to improvement of the body and skin appearance, for example enhancing the appearance of sagging, wrinkled, or cellulite-afflicted areas of the skin and body,...
US20090060977 DEVICES, SYSTEMS AND METHODS FOR TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER CONDITIONS  
Devices, systems and methods for compressing, cutting, incising, reconfiguring, remodeling, attaching, repositioning, supporting, dislocating or altering the composition of tissues or anatomical...
US20080279845 COMBINATION THERAPY WITH A COMPOUND ACTING AS A PLATELET ADP RECEPTOR INHIBITOR  
The present invention is directed to pharmaceutical compositions and methods of using combination therapies containing...
US20080051490 Medical Devices and Applications of Polyhydroxyalkanoate Polymers  
Devices formed of or including biocompatible polyhydroxyalkanoates are provided with controlled degradation rates, preferably less than one year under physiological conditions. Preferred devices...
US20080038306 Fluidic Tissue Augmentation Compositions and Methods  
Compositions and method for augmenting tissue after delivery to localized area. The compositions include a hydrogel and a dermal filler. The hydrogel can polymerize and/or crosslink upon a first...
US20080019975 Novel Regimens for Treating Diseases and Disorders  
Methods and materials are provided for induction-maintenance regimens of targeted anti-inflammatory therapies (TATs) for treatment of a variety of diseases and disorders. Preferred embodiments...
US20080015155 Compositions and Methods for the Treatment of Inflammatory Conditions of the Mucosae, Skin and the Eye  
The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but...
US20070269481 Biomimetic Scaffolds  
The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer are aligned, and a molecule is covalently attached, either directly or through a...
US20070264271 Potent Immunostimulatory from Microalgae  
Immunostimulatory polysaccharides can be preferentially extracted from food-grade microalgae using an aqueous ethanol extraction procedure. The resulting preparations exhibit extremely potent...
US20070244049 COMPOSITIONS AND METHODS FOR ENHANCED MUCOSAL DELIVERY OF PARATHYROID HORMONE  
Pharmaceutical compositions and methods are described comprising at least a parathyroid hormone peptide (PTH) preferably PTH1-34 and one or more mucosal delivery-enhancing agents for enhanced...
US20070202186 Apparatus and formulations for suprachoroidal drug delivery  
Drug formulations, devices and methods are provided to deliver biologically active substances to the eye. The formulations are delivered into scleral tissues adjacent to or into the suprachoroidal...
US20070141145 HYDROPHOBIC CORE CARRIER COMPOSITIONS FOR DELIVERY OF THERAPEUTIC AGENTS, METHODS OF MAKING AND USING THE SAME  
The present invention relates, in part, to a biocompatible hydrophobic-core carrier comprising a carrier, and a plurality of hydrophobic groups covalently linked to the polymeric carrier. The...
US20070077292 Compositions and methods for improved skin care  
Compositions and methods for administering collagen to a human subject have been developed. The collagen-containing lipid vesicles of the invention provide a delivery system for human collagen...
US20070037737 Composition and method for the repair and regeneration of cartilage and other tissues  
The present invention relates to a new method for repairing human or animal tissues such as cartilage, meniscus, ligament, tendon, bone, skin, cornea, periodontal tissues, abscesses, resected...
US20060263355 Treatment of bone disorders  
Methods of treatment of various bone indications, such as osteoporosis, in a mammal are provided wherein an effective amount of an antagonist that binds to a B-cell surface marker, such as a CD20...
US20060247183 Compositions and methods for the treatment of inflammatory conditions of mucosae, skin and the eye  
The present invention relates to compositions comprising a proanthocyanidin, as well as methods for using such compositions in the treatment of an inflammatory condition of the skin including, but...
US20060198814 Anti-infectious hydrogel compositions  
The present invention provides a hydrogel composition capable of preventing the intrusion of micro-organisms into body cavities or body openings of mammals comprising of a poly(N-vinyl lactam), a...
US20060193887 Medical devices having nanoporous bonding layers  
The present invention relates generally to medical devices with therapy eluting components and methods for making same. More specifically, the invention relates to implantable medical devices...
US20060128655 Use of hyaluronic acid or its derivatives to enhance delivery of antineoplastic agents  
A combination for administration to a mammal which combination employs a therapeutically effective amount of a medicinal and/or therapeutic agent to treat a disease or condition and an amount of...
US20060029611 Prevention and treatment of amyloidogenic disease  
The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid...
US20050266067 Nanocell drug delivery system  
Nanocells allow the sequential delivery of two different therapeutic agents with different modes of action or different pharmacokinetics. A nanocell is formed by encapsulating a nanocore with a...
US20050260153 Facilitation of iontophoresis using charged moieties  
The invention provides compositions and methods for making and using sterically enhanced antagonist aptamer conjugates that include a nucleic acid sequence having a specific affinity for a target...
US20050220882 Materials for medical implants and occlusive devices  
An embodiment is a swellable medical device that swells after introduction into a patient to occlude a lumen or void in a patient. The device may be anisotropically swellable so that it swells...
US20050163788 Prevention and treatment of amyloidogenic disease  
The invention provides compositions and methods for treatment of amyloidogenic diseases. Such methods entail administering an agent that induces a beneficial immune response against an amyloid...
US20050118206 Surfactant-based gel as an injectable, sustained drug delivery vehicle  
The present invention provides methods and compositions for the sustained delivery of beneficial agents. In certain embodiments, the invention provides compositions comprising a surfactant, a...
US20160143940 VEHICLE FOR DELIVERING A COMPOUND TO A MUCOUS MEMBRANE AND RELATED COMPOSITIONS, METHODS AND SYSTEMS  
PSA is delivered to the host by outer membrane vesicles (OMVs), secretion structures that target bacterial molecules to host cells. Purified OMVs direct the in vitro differentiation of functional...
US20150297790 HYALURONIC ACID-BASED GELS INCLUDING LIDOCAINE  
Disclosed herein are cohesive soft tissue fillers, for example, dermal and subdermal fillers, based on hyaluronic acids and pharmaceutically acceptable salts thereof. In one aspect, hyaluronic...
US20150045321 HYALURONIC ACID BASED FORMULATIONS  
Disclosed herein are soft tissue fillers, for example, dermal and subdermal fillers, based on low molecular weight hyaluronic acids and pharmaceutically acceptable salts thereof, and methods of...
US20140371169 AQUEOUS IRON CARBOHYDRATE COMPLEXES, THEIR PRODUCTION AND MEDICAMENTS CONTAINING THEM  
A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron(III) salt and an aqueous solution of the oxidation product of one or more maltrodextrins using an aqueous...
US20140349959 POLYSACCHARIDE GEL FORMULATION HAVING INCREASED LONGEVITY  
Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps...
US20140296179 NUTRITIONAL COMPOSITION COMPRISING IMMUNOGLOBULINS AND OLIGOSACCHARIDES  
The present invention provides a method and composition for the treatment and/or prevention of infection, said method comprising orally administering a composition to a mammal, said composition...
US20140255477 Compositions and Methods for Delivery of High-Affinity Oxygen Binding Agents to Tumors  
While tumor hypoxia is recognized as a key barrier to effective chemo and radiation therapy of solid tumor malignancies, and an important biological mediator of more aggressive tumor phenotype and...
US20140107063 OSTEOARTHRITIS DIET FORMULATIONS  
Dietary formulations and methods for treating, preventing or delay onset of osteoarthritis in canines and other animals are disclosed. The formulations are enriched in n-3 fatty acids and limited...