Matches 1 - 50 out of 70 1 2 >


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US20130338165 Use of Compounds Elevating Glutathione Levels for the Treatment of Parkinson's Disease  
Methods of treating Parkinson's Disease comprising administering compounds that up-regulate cystine-glutamate exchange (system Xc−) and/or increase glutathione levels in the brain cells. Preferred...
US20140005262 RACECADOTRIL LIPID COMPOSTIONS  
A lipid composition comprising racecadotril, at least one surfactant and a lipid.
US20110196034 Green garlic and methods of production  
A new vegetable, referred to herein as green garlic, grown from garlic bulbils is disclosed. In particular examples, the green garlic is rich in one or more thiosulfinates. Methods of producing...
US20120115946 Formulation  
The present invention relates to a hygroscopic matrix based formulation, a process for the preparation thereof and its use in the treatment of diseases.
US20140275246 RACECADOTRIL LIPID COMPOSITIONS  
A lipid composition comprising racecadotril, at least one surfactant and a lipid.
US20060154984 Therapeutic use of acyl glycerols and the nitrogen- and sulphur- containing analogues thereof  
The invention relates to the use of acyl glycerols and the nitrogen- and sulfur-containing analogues thereof in the therapeutic field, particularly in human health. The inventive compounds have...
US20120220596 CYSTEINE AND CYSTINE PRODRUGS TO TREAT SCHIZOPHRENIA AND REDUCE DRUG CRAVINGS  
The present invention provides cysteine and cystine prodrugs for the treatment of schizophrenia and drug addiction. The invention further encompasses pharmaceutical compositions containing...
US20110245262 COMPOUNDS FOR TREATING PROLIFERATIVE DISORDERS  
Disclosed are compounds and methods of using compounds of the invention for treating a subject with a proliferative disorder, such as cancer, and methods for treating disorders responsive to Hsp70...
US20150133544 ETHYL (2R)-2-ACETAMIDO-3-(4-METHYLBENZOYLSULFANYL)PROPANOATE AND USES THEREOF  
A novel substituted N-acetyl-L-cysteine (NAC) derivative and methods of using this compound for the treatment of diseases and/or conditions, including but not limited to diseases and/or conditions...
US20120301439 INHIBITION OF CHOROIDAL NEOVASCULARIZATION  
Methods of treatment of diseases that include or are characterized by inappropriate or pathological neovascularization are disclosed. These diseases include diseases of the eye, such as diabetic...
US20120122844 METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY  
The present invention provides the use of a neutral endopeptidase inhibitor, in the manufacture of a medicament for the treatment, amelioration and/or prevention of contrast-induced nephropathy....
US20060252827 Therapeutic use of of acyglycerols and the nitrogen-and sulphur-containing analogues thereof  
The invention relates to the use of acylglycerols and the nitrogen- and sulfur-containing analogues thereof in therapy, particularly for the treatment of cerebral ischemia. The invention further...
US20100267801 CYCLOHEXYL SULPHONES FOR TREATMENT OF CANCER  
Sulphones of formula (I) are disclosed for use in treatment of cancer.
US20140364493 METHOD OF INHIBITING REMNANT LIPOPROTEIN PRODUCTION  
The present invention aims at provision of a method for inhibiting remnant lipoprotein production and a remnant lipoprotein production inhibitor, which includes administering a compound having a...
US20150133470 SUBSTITUTED N-ACETYL-L-CYSTEINE DERIVATIVES AND RELATED COMPOUNDS  
Novel substituted N-acetyl-L-cysteine (NAC) derivatives and related compounds and methods of using these compounds for the treatment of diseases and/or conditions, including but not limited to...
US20090312358 METHOD FOR MANAGEMENT OF DIARRHEA  
The present invention is directed to methods of treatment and/or management of diarrhea, such as chronic diarrhea using sequential administration of opioid agonists to suppress gut mobility and...
US20050085448 Production of pure stereoisomers of tricyclo[5.2.1.0 2.6]-dec-9-yl-xanthogenate and medicaments therefrom  
The invention relates to pharmaceutical formulations containing exo/exo-tricyclo[5.2.1.02.6]-dec-9-yl-xanthogenate, drugs containing exo/exo-tricyclo[5.2.1.02.6]-dec-9-yl-xanthogenate as active...
US20120234721 DIURETIC AND DIURETIC-LIKE COMPOUND ANALOGS  
The present invention provides compounds that are effective in treating central nervous system disorders and maintaining normal brain function. Methods of making and using the compounds are also...
US20120148662 Formulation  
The present invention relates to a novel stable S-[2-([[1-(2-ethylbutyl)-cyclohexyl]-carbonyl]amino)phenyl]2 -methylpropanethioate liposomal composition, a process for the preparation thereof and...
US20050031717 Salt taste modification  
The pharmacology of the capsaicin receptor has been discovered to be predictive of the enhancement of the non-specific salt taste channel. Salt taste in a mammal may be modified by introducing to...
US20140336254 Small Molecules That Covalently Modify Transthyretin  
A family of covalent kinetic stabilizer compounds that selectively and covalently react with the prominent plasma protein transthyretin in preference to more than 4000 other human plasma proteins...
US20120270938 SMALL MOLECULES THAT COVALENTLY MODIFY TRANSTHYRETIN  
A family of covalent kinetic stabilizer compounds that selectively and covalently react with the prominent plasma protein transthyretin in preference to more than 4000 other human plasma proteins...
US20110190368 Organosulfur Compounds, a Method of Making Organosulfur Compounds and their Use for Inhibiting the Growth of Tumour Cells  
Organosulfur compounds of the general formula (2) are described, wherein R1 and R2 are linear or branched C1-C5 alkyl; linear or branched C1-C5 alkenyl with the proviso that R1 is not prop-1-enyl...
US20070032476 Aminothiolester compounds, pharmaceutical and cosmetic compositions containing same and uses thereof  
The invention relates to novel aminothiol ester compounds having the general formula (I): and to a method for preparing them and to their use in pharmaceutical compositions intended for use in...
US20080131503 Stable Pharmaceutical Composition Comprising a Fixed Dose Combination of Fenofibrate and an Hmg-Coa Reductase Inhibitor  
A pharmaceutical composition for oral administration comprising a fixed dose combination of a first solid pharmaceutical composition containing fenofibrate as the active substance and second solid...
US20050197390 Thiol ester compositions and processes for making and using same  
Thiol ester compositions, methods of making the thiol ester compositions, and methods of using the thiol ester compositions are provided. In some embodiments, the thiol ester compositions include...
US20130281520 Anti-Inflammatory And Antioxidant Conjugates Useful For Treating Metabolic Disorders  
The present invention is directed to methods for treating metabolic disorders with compounds that are conjugates. The conjugates of the present invention are comprised of salicylic acid,...
US20090005445 Article comprising calcium for reducing the production of TSST-1  
Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when...
US20050170015 Antiproliferative colchicine compositions and uses thereof  
A method of treatment of a host with a cellular proliferative disease, including contacting the host with a colchicine family member such as thiocolchicine and an antiproliferative agent, each in...
US20080194681 Novel Inhibitors of Histone Deacetylase for the Treatment of Disease  
Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of his-tone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of...
US20150031715 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING VLA-4  
The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula...
US20130197059 INTEGRIN ANTAGONIST CONJUGATES FOR TARGETED DELIVERY TO CELLS EXPRESSING LFA-1  
The invention relates to compounds of formula I: wherein R1, R2, and n are defined in the detailed description and claims. In particular, the present invention relates to the compounds of formula...
US20070259943 ORTHO-SUBSTITUTED PENTAFLUOROSULFANYL BENZENES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS SYNTHESIS INTERMEDIATES  
This invention relates to novel substituted pentafluorosulfanylbenzenes of the formula I: and/or salts thereof as claimed, for use as a synthetic intermediates for preparing medicaments,...
US20060270705 Method for inhibiting lipid absorption and lipid absorption inhibitor  
The present invention relates to a method of inhibiting lipid absorption through the small intestine, which comprises administering a compound having a CETP inhibitory activity to an...
US20080300303 Substances and Pharmaceutical Compositions for the Inhibition of Glyoxalases and Their Use As Anti-Fungal Agents  
The present invention pertains to substances of the formula (I) wherein X is O or S; and R1-R4 are defined in the claims as inhibitors of glyoxalase I and/or II, pharmaceutical compositions...
US20140155442 ANTI-OBESITY AGENT COMPRISING HIGH-PURITY EPA  
The present invention provides an agent for preventing the increase in a body weight (or for decreasing a body weight) or an anti-obesity agent each comprising at least one component selected from...
US20120213827 PROCESS FOR CONTROLLED CRYSTALLIZATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT FROM SUPERCOOLED LIQUID STATE BY HOT MELT EXTRUSION  
A process for controlling the crystallization of certain hydrophobic active pharmaceutical ingredients (APIs) from a supercooled liquid state by hot-melt extrusion processing is described. Also...
US20100286073 COMPOUNDS AND METHODS FOR PHARMACEUTICAL USE  
The present invention relates to compounds, as well as to compositions, methods and kits comprising such compounds, for use in the treatment or prophylaxis of fibromyalgia, chronic fatigue...
US20100105685 S-Nitrosothiol Compounds and Related Derivatives  
The present invention is directed to a method of treating a lack of normal breathing control including the treatment of apnea and hypoventilation associated with sleep, obesity, certain medicines...
US20140005261 RACECADOTRIL LIQUID COMPOSITIONS  
A liquid composition comprising racecadotril and cyclodextrin.
US20070015827 Methods and compositions for treating ophthalmic conditions via serum retinol, serum retinol binding protein (RBP), and/or serum retinol-RBP modulation  
Compounds that reduce serum retinol, serum RBP, and/or serum retinol-RBP levels may be used to treat ophthalmic conditions associated with the overproduction of waste products that accumulate...
US20140045765 METHOD FOR INHIBITING AUTOPHAGY OF MOTOR NEURONS  
A method for inhibiting the autophagy of motor neurons in a subject is provided. The method comprises administrating to the subject an effective amount of an active ingredient selected from the...
US20140221476 COMPOUND, COMPOSITION AND USES THEREOF  
The disclosure herein provides the compounds of Formulas 1 and its pharmaceutical acceptable salts, as well as polymorphs, solvates, and hydrates thereof. These salts may be formulated as...
US20130225680 COMPOUND, COMPOSITION AND USES THEREOF  
The disclosure herein provides the compounds of Formulas 1 and its pharmaceutical acceptable salts, as well as polymorphs, solvates, and hydrates thereof. These salts may be formulated as...
US20100047327 Adjuvant for Transdermal or Transmucosal Administration and Pharmaceutical Preparation Containing the Same  
It is intended to provide a low molecular weight adjuvant which can be administered safely without inducing skin irritation or the like by transdermal or transmucosal administration and is for...
US20130143962 Adamantyl Derivatives as Therapeutic Agents  
The present invention relates to adamantyl derivatives and their anti-cancer activity. Compounds of formulae I and II are provided as well as related methods of treatment and methods of synthesis.
US20110288168 HISTONE DEACETYLASE INHIBITORS  
Histone deacetylase is a metallo-enzyme with zinc at the active site. Compounds having a zinc-binding moiety, such as, for example, a hydroxamic acid group or a carboxylic acid group, can inhibit...
US20140171502 New Process  
The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl] 2-methylthiopropionate which is useful as a pharmaceutically active compound.
US20120157504 New Process  
The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]2-meth ylthiopropionate which is useful as a pharmaceutically active compound.
US20110224156 Propionic Acids, Propionic Acid Esters, and Related Compounds  
The invention relates to propionic acids, propionic acid esters, and related compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds for the...

Matches 1 - 50 out of 70 1 2 >