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US20140105886 ASSOCIATION OF BIOMARKERS WITH PATIENT OUTCOME  
Glioblastoma multiforme (GBM) is an aggressive form of brain cancer. Biomarkers for GBM that provide prognostic and predictive information are useful because they provide the physician valuable...
US20150250717 DRUG DELIVERY SYSTEMS AND METHODS FOR TREATMENT OF BLADDER CANCER WITH GEMCITABINE  
Drug delivery devices and methods are provided for administering gemcitabine to a patient in need of treatment of bladder cancer by intravesically administering gemcitabine into the bladder of the...
US20120309706 COMBINED TREATMENT OF PANCREATIC CANCER WITH GEMCITABINE AND MASITINIB  
The present invention relates to the combined treatment of pancreatic cancers, especially in patients with metastasis and in patients whose cancer is developing resistance to first line treatment...
US20150165178 DRUG DELIVERY SYSTEMS AND METHODS FOR TREATMENT OF BLADDER CANCER  
Methods, devices, and medicaments that include oxaliplatin are provided for use in the treatment of bladder cancer by locally administering oxaliplatin into the bladder of a patient to achieve a...
US20140199403 METHODS OF TREATING PANCREATIC CANCER  
Provided herein are methods for the treatment of metastatic pancreatic cancer comprising administration of a composition comprising nanoparticles comprising a taxane (such as paclitaxel) and a...
US20150224104 METHODS FOR THE TREATMENT OF LOCALLY ADVANCED BREAST CANCER  
Provided herein are methods of treating, preventing and/or managing locally advanced breast cancer, including inflammatory breast cancer, which comprise administering to a patient one or more...
US20130345164 TREATMENTS FOR CELLULAR PROLIFERATIVE DISORDERS AND IDENTIFICATION THEREOF  
This invention concerns methods of identifying treatments for treating various disorders and related computer products and systems. Also disclosed are methods for treating cellular proliferative...
US20120201747 System and Method for Diagnosis and Treatment  
This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy...
US20140378534 TREATMENT AND DIAGNOSIS OF COLON CANCER  
The present invention discloses novel agents and methods for diagnosis and treatment of colon cancer. Also disclosed are related arrays, kits, and screening methods.
US20140221301 COMBINATION TREATMENT FOR CANCER  
A method of treating a cancer comprising administering to a subject in need thereof an effective amount of a glycylcycline, for example tigecycline in combination with a chemotherapeutic such as...
US20130121912 MICRORNA-198 AS A TUMOR SUPPRESSOR IN PANCREATIC CANCER  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
US20140349957 Compositions for Photodynamic Therapy Chemically Modified to Increase Epithelia Penetration and Cellular Bioavailability  
The present invention describes a photodynamic prodrug, i.e., a substituted 4-thiothymidine (4-TT), which is able to cross the body's epithelia tissues such as the skin, oral cavity, nasal cavity,...
US20110033422 TREATMENTS FOR FLAVIVIRIDAE VIRUS INFECTION  
The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
US20140094428 DOSAGE REGIMEN FOR SAPACITABINE AND DECITABINE IN COMBINATION FOR TREATING ACUTE MYELOID LEUKEMIA  
A first aspect of the invention relates to a method of treating AML in a subject, said method comprising administering to a subject a therapeutically effective amount of (i) sapacitabine, or a...
US20120295864 METHOD FOR TREATING ACUTE MYELOID LEUKEMIA  
The present invention relates to the use of BI 6727 or a salt thereof or the hydrate thereof for treating patients suffering from acute myeloid leukemia (AML) comprising the administration of a...
US20150254433 Methods and Models for Determining Likelihood of Cancer Drug Treatment Success Utilizing Predictor Biomarkers, and Methods of Diagnosing and Treating Cancer Using the Biomarkers  
A method of identifying one or more biomarkers associated with one or more drugs effective to stop or repress proliferation of cancer cells, and a system for predicting effectiveness of the same....
US20100305058 INDIVIDUALIZED CANCER TREATMENTS  
The invention provides for compositions and methods for predicting an individual's responsitivity to cancer treatments and methods of treating cancer. In certain embodiments, the invention...
US20150164933 DOSAGE REGIMEN FOR SAPACITABINE AND SELICICLIB  
A first aspect of the invention relates to a method of treating a proliferative disorder in a subject, said method comprising administering to the subject a therapeutically effective amount of (i)...
US20150110773 TARGETING THE GLUTAMINE TO PYRUVATE PATHWAY FOR TREATMENT OF ONCOGENIC KRAS-ASSOCIATED CANCER  
Methods and kits for GPP-targeting, e.g., for the treatment of oncogenic Kras-associated cancers, and methods for determining the efficacy of those methods are provided.
US20120135950 ANTIVIRAL TREATMENT OF LYMPHOMA AND CANCER  
Compositions and methods to treat lymphoma and cancer are disclosed. In particular, the method teaches treatment of lymphoma and cancer using anti-HERV-K(HML-2) therapies. Further taught are...
US20130011411 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS, AND TREATMENT OF CANCER  
Methods and compositions for diagnosing and treating cancer, such as breast cancer are provided. In particular, methods and compositions relating to nucleic acids encoding DACH1 and DACH1 proteins...
US20140314750 Six-Gene Biomarker of Survival and Response to Platinum Based Chemotherapy in Serious Ovarian Cancer Patients  
Described herein are methods of predicting the risk of developing ovarian cancer recurrence of a subject comprising the steps of detecting the expression levels of at least four of the six genes...
US20150246067 ANTIVIRAL TREATMENT OF LYMPHOMA AND CANCER  
The present invention provides compositions and methods to treat lymphoma and cancer. In particular, the present invention provides treatment of lymphoma and cancer using anti-HERV-K(HML-2)...
US20120201872 LIPOSOMES COMPRISING A CALCIUM PHOSPHATE-CONTAINING PRECIPITATE  
Provided herein are methods and compositions for the delivery of bioactive compounds to a cell, tissue, or physiological site. The compositions comprise delivery system complexes comprising...
US20140234295 ISOFLAVONOID COMPOUNDS AND METHODS FOR THE TREATMENT OF CANCER  
Provided herein is a pharmaceutical composition comprising at least one isoflavonoid. Also provided herein are methods of treating cancer, sensitizing cancer cells, and inducing apoptosis in...
US20110118528 Methods and Nutritional Formulations to Increase the Efficacy and Reduce the Side Effects of Cancer Treatment  
The present invention relates to methods of protecting patients and sensitizing cancer cells in combination with chemotherapy and/or radiation therapy. More specifically, the invention provides...
US20120321552 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20110104050 Compositions and Methods for Identifying and Targeting Cancer Cells of Alimentary Canal Origin  
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or...
US20120237502 METHOD FOR TREATING BREAST CANCER AND OVARIAN CANCER  
The present invention relates to a method for the prevention or treatment of certain breast cancers or ovarian cancer comprising administering to a patient in need thereof of a therapeutically...
US20140100188 PHENOTYPING TUMOR-INFILTRATING LEUKOCYTES  
The present disclosure relates to an immune signature of tumor infiltrating leukocytes. In particular, the disclosure provides methods and kits for determining the immune signature of tumor...
US20150259751 MOLECULAR SIGNATURE FOR AGGRESSIVE SQUAMOUS CELL CARCINOMAS OF THE HEAD AND NECK  
The present invention encompasses methods of classifying HNSCC tumors, such as OSCC tumors, as aggressive or, alternatively, indolent.
US20130084328 METHYLATED CODING AND NON-CODING RNA GENES AS DIAGNOSTIC AND THERAPEUTIC TOOLS FOR HUMAN MELANOMA  
Provided herein are methods for the diagnosis and treatment of human melanoma and prediction of early disease genesis to metastasis by assessing CpG island methylation or expression level of...
US20140080783 PHARMACEUTICAL COMBINATIONS FOR TREATMENT OF SPECIFIC CANCERS  
The present invention relates to the field of oncology and provides compositions and methods for treating specific cancers, including non small cell lung cancer, breast cancer, thyroid cancer,...
US20120071435 PHARMACEUTICAL COMBINATIONS COMPRISING FOR THE TREATMENT OF SPECIFIC CANCERS  
The present invention relates to the field of oncology and provides compositions and methods for treating specific cancers, including non small cell lung cancer, breast cancer, thyroid cancer,...
US20120196828 SENSITIZATION OF CANCER CELLS TO TREATMENT  
The present application provides methods for the treatment of cancer, comprising administering substantially non-anticoagulant 2-O, 3-O desulfated heparin to patients suffering from cancer that...
US20130288995 METHODS FOR ADMINISTRATION OF CITICOLINE IN STROKE TREATMENT  
The present invention provides administration methods for CDPC for treating stroke. CDPC was delivered via ECS at a concentration of 40 mmol/L-60 mmol/L. In a specific embodiment of the present...
US20110123488 Method of Treatment for Cancers Associated with Elevated HER2 Levels  
Novel methods of treating proliferative disorders characterized by elevated Her-2, and the patient is then administered an effective amount of an HSP90 inhibitor.
US20150148307 METHODS AND COMPOSITIONS FOR THE PROGNOSIS AND TREATMENT OF RELAPSED LEUKEMIA  
The present invention is directed to methods of prognosing relapsed leukemia in a subject. These methods are based on the detection of one or more relapse-specific gene mutations in a patient...
US20120128667 PENTAMIDINE COMBINATIONS FOR TREATING CANCER  
The present invention relates to the treatment of cancer, e.g., ovarian cancer, breast cancer, pancreatic cancer or colon cancer, with pentamidine and (a) oxaliplatin, (b) gemcitabine, (c) taxol,...
US20120245117 METHODS OF TREATING SQUAMOUS CELL LUNG CANCER WITH 4-IODO-3-NITROBENZAMIDE IN COMBINATION WITH GEMCITABINE AND CARBOPLATIN  
In one aspect, the present invention provides a method of treating squamous cell lung cancer in an individual comprising administering to the individual having lung cancer an effective amount of...
US20140328904 GLA MONOTHERAPY FOR USE IN CANCER TREATMENT  
The present disclosure relates generally to compositions and methods for treating cancer with a glucopyranosyl lipid A (GLA) in the absence of antigen.
US20110028421 Use of alkylphosphocholines in combination with antimetabolites for the treatment of benign and malignant oncoses in humans and mammals  
The invention relates to the use of alkylphosphocholines in combination with antimetabolites for the treatment of multiple myeloma, colon cancer or renal cancer. Preferred alkylphosphocholines are...
US20120190639 TREATMENT OR PROPHYLAXIS OF PROLIFERATIVE CONDITIONS  
The invention relates to novel compounds for use in the treatment or prophylaxis of cancers and other proliferative conditions that are for example characterized by cells that express cytochrome...
US20140248375 Combination Therapy for Treating Proliferative Diseases  
The present invention relates generally to new chemical combinations and methods for their use in the treatment of proliferative diseases and in particular cancer.
US20140220006 LUNG CANCER BIOMARKERS  
The present invention relates to methods of diagnosing lung cancer in a patient, as well as methods of monitoring the progression of lung cancer and/or methods of monitoring a treatment protocol...
US20110212176 CICLOPIROX AND CYTARABINE FOR THE TREATMENT OF LEUKEMIC DISORDERS  
The present application relates to compositions and methods for treating leukemic disorders. In particular, the present application relates to compositions and methods for treating the leukemic...
US20090060871 ADMINISTRATION OF AGONIST-ANTAGONIST IN OPIOID-DEPENDENT PATIENTS  
A method for reducing psychological opioid dependence includes selecting a patient addicted to an opioid and administering to the patient an opioid agonist-antagonist for at least 14 days, thereby...
US20140302174 Combination Therapy for Ovarian Cancer  
The present invention provides a method of treating ovarian cancer in a mammal in need of such treatment comprising administering an effective amount of a combination of gemcitabine, cisplatin or...
US20150165177 DRUG DELIVERY SYSTEMS AND METHODS FOR TREATMENT OF PROSTATE  
Methods, devices, and medicaments that include a drug are provided for use in the treatment of the prostate by locally administering the drug into the bladder of a patient to achieve a sustained...
US20130004482 Methods of Treating Breast Cancer with Anthracycline Therapy  
The application describes methods for screening subjects with breast cancer to determine if the breast cancer will be responsive to a breast cancer therapy including an anthracycline. The...