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US20130079296 METHOD FOR ASSAYING LOWER RESPIRATORY TRACT INFECTION OR INFLAMMATION  
The present invention relates to a reliable method of prediction of lower respiratory tract infection or inflammation in humans, wherein the level of pancreatic stone protein/regenerating protein...
US20150182410 PNEUMATIC WRAP COMPRESSION TREATMENTS FOR VENOUS CONDITIONS  
A method of treatment of a condition such as deep vein thrombosis, arterial insufficiency, lymphedema, pulmonary embolism, and pain includes use of a pneumatic compression wrap, pump, and...
US20150086631 Multi-Functional Micro and Nanoparticles for Use in Root Canal Therapies  
Chitosan nanoparticles are provided for use in the in vivo treatment of connective tissues in root canal therapies. The nanoparticles are optionally linked with one or more photoactivatable...
US20130011411 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS, PROGNOSIS, AND TREATMENT OF CANCER  
Methods and compositions for diagnosing and treating cancer, such as breast cancer are provided. In particular, methods and compositions relating to nucleic acids encoding DACH1 and DACH1 proteins...
US20120309672 TREATMENT OF EXTRACELLULAR MATRIX TO REDUCE INFLAMMATION  
Pharmaceutical compositions are provided. The compositions comprise a compound comprising the hyaluronan-containing structure A-(low molecular weight hyaluronan domain)-B. The compositions also...
US20140271561 METHODS OF DIAGNOSIS, SELECTION, AND TREATMENT OF DISEASES AND CONDITIONS CAUSED BY OR ASSOCIATED WITH METHANOGENS  
The invention described herein provides for methods and systems for determining, selecting, and/or treating diseases and conditions caused by or associated with high quantities of methanogens in a...
US20120087980 STIMULATION OF NEUROREGENERATION BY FLAVONOID GLYCOSIDES  
Flavonoid glycosides, such as isoquercitrin, are shown to stimulate the formation of neuritis and neuronal synapses in neurons and neuronal progenitor (stem) cells.
US20110178379 TISSUE ASSESSMENT  
A method of aiding in the diagnosis or prediction of degenerative joint disease in a joint of a patient. The method comprises obtaining a test spectrum of Raman scattered radiation from cartilage...
US20120052124 SILK FIBROIN SYSTEMS FOR ANTIBIOTIC DELIVERY  
The present invention provides for silk fibroin-based compositions comprising one or more antibiotic agents for prevention or treatment of microbial contamination, methods of making...
US20130102555 METHOD OF TREATING DIABETES  
Methods are provided for treating diabetes, lowering plasma level of HbA1c, glucose plasma levels, total cholesterol plasma level, and/or triglyceride plasma level while increasing HDL cholesterol...
US20110195921 ELIMINATION OF A CONTAMINATING NON-HUMAN SIALIC ACID BY METABOLIC COMPETITION  
The disclosure provides a method of reducing or eliminating Neu5Gc in a cell culture or in a human subject. The method includes flooding the system with the human sialic acid i\7-acetylneuraminic...
US20150079055 USE OF SECRETOR, LEWIS AND SIALYL ANTIGEN LEVELS IN CLINICAL SAMPLES AS PREDICTORS OF RISK FOR DISEASE  
An individual at risk for necrotizing enterocolitis and related disorders can be identified by measuring the level of at least one secretor antigen in a biological sample from the individual and...
US20140309185 Inhibiting G Protein Coupled Receptor 6 Kinase Polypeptides  
This document relates to inhibitors of G protein coupled receptor 6 kinase (GRK6) polypeptides as well as methods and materials for using such inhibitors to treat hematological malignancies,...
US20150197536 COMPOUNDS REDUCING THE PRODUCTION OF SORBITOL IN THE EYE AND METHODS OF USING THE SAME  
Methods of inhibiting the progression of or treating secondary complications of diabetes, especially a diabetic eye disease, in a mammal by inhibiting the production of sorbitol in the mammal....
US20110144030 CONJUGATE OF HYALURONIC ACID FOR COSMETIC TREATMENT AND PREPARATION METHOD  
This invention discloses a new conjugate compound that comprises at least one HA oligomer derivatised through one thiolated linker, whereby it binds to at least one metal nanoparticle, such as,...
US20120207737 MEDICAL UTILITY OF GLYCAN-BINDING PROTEINS AND GLYCANS  
The present invention relates to the use of glycan-binding polypeptides and glycans as a medicament, in particular for treating and/or preventing helminthic infections or an immune disease....
US20140315781 METHODS OF TREATING FATTY LIVER DISEASE WITH HELMINTH-DERIVED GLYCAN-CONTAINING COMPOUNDS  
The present invention provides a compound comprising a helminth-derived glycan and/or glycoconjugate thereof (e.g., a compound comprising a Lewisx antigen (e.g., LNFPIII), a non-Lewisx antigen...
US20110044901 NOVEL COMPOUNDS  
The present invention is directed to sulphated compounds comprising at least one glycosidic amine group, and polysaccharide, oligosaccharide, peptide and protein derivatives comprising such...
US20100323033 CANCER SENSITIZER COMPRISING CHLOROGENIC ACID  
The present invention relates to a cancer sensitizer comprising chlorogenic acid or a derivative thereof. In particular, the present invention relates to a cancer sensitizer comprising chlorogenic...
US20130137653 THEANINE DERIVATIVE, PREPARATION METHOD THEREOF, AND USE THEREOF FOR ALLEVIATING ACNE  
The present invention relates to a theanine derivative, a preparation method thereof, and a use thereof for anti-acne treatment, having a selective inhibitory effect on Propionibacterium acnes in...
US20100297046 Compositions and Methods Related to Fructosamine-3-Kinase Inhibitors  
The invention relates to compounds and methods for inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin, by way of fructosamine-3-kinase inhibition,...
US20080206290 COSMETIC COMBINATION PRODUCT FOR IMPROVING APPEARANCE  
A cosmetic combination product, wherein the product comprises at least two components selected from (a) one or more dietary supplements, (b) one or more cosmetic preparations for topical...
US20130072427 GPR 119 MODULATORS  
Compounds of formula (I) that modulate the activity of the G-protein-coupled receptor GPR119 and their uses in the treatment of diseases linked to the modulation of the G-protein-coupled receptor...
US20110053880 COMPOSITION FOR TREATMENT OF TUBERCULOSIS  
The invention relates to a pharmaceutical composition comprising a compound preventing EthR from binding to the ethA promoter, for example a compound of formula 1 wherein R1 is optionally...
US20050085432 Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections  
A method of treating a bacterial infection in an individual is provided. The method is effected by administering to the individual a therapeutically effective amount of a pharamaceutical...
US20130261071 EXOPOLYSACCHARIDE  
An isolated polysaccharide has the structure [-β(1,3)-D-GaIpNAc-β(1,4)-D-Glcp-]n. The polysaccharide may be from a Bifidobacterium strain NCIMB 41003. The polysaccharide exhibits immunomodulatory...
US20130058998 ENCAPSULATED N-ACETYLMANNOSAMINE OR N-ACETYLNEURAMINIC ACID TO INCREASE SIALYLATION  
A method for treating a disorder characterized by hyposialylation in a subject that includes administering to the subject an effective amount of (i) a composition comprising N-acetylmannosamine,...
US20150051165 APPLICATION OF DEPOLYMERIZED HOLOTHURIAN GYLCOSAMINOGLYCANS (DHG) IN PREPARATION OF DRUG FOR PREVENTION AND TREATMENT OF THROMBOEMBOLIC DISEASES  
The present invention discloses an application of depolymerized holothurian glycosaminoglycans (DHG) in preparation of a drug for the prevention and treatment of thromboembolic diseases. The DHG...
US20050084550 Weight reduction and maintenance method for animals  
Disclosed is a “Pet Food Formulation System” (PFFS) that is a “treatment system” that results in loss of weight by pets consuming ad libitum, or in controlled rations, a reduced calorie pet food....
US20110178037 HYDROPHOBICALLY ENHANCED AMINOGLYCOSIDES  
Hydrophobically enhanced aminoglycosides have been prepared and shown to be effective antibacterial agents. These agents may be used in the treatment or prevention of various bacterial infections....
US20100249048 BETA GLYCOLIPIDS FOR THE TREATMENT OF CALCIFICATION RELATED DEGENERATIVE DISORDERS  
The present invention relates to a composition comprising a combination of at least one natural or synthetic β-glycolipid, a mixture of at least two β-glycolipids, a substance which increases the...
US20110190385 Methods and Products for Reawakening Retrocyclins  
Products and methods are provided for the restoring the endogenous expression of theta-defensins, such as retrocyclin-1, in mamallian cells. The present invention also includes products and...
US20140336140 METHODS FOR PROVIDING SIALYLATED OLIGOSACCHARIDES  
The invention relates to a method for providing analogs of human milk oligosaccharides (HMO), in particular oligosaccharides containing terminal sialic acid. The method comprises the steps of: a)...
US20140243281 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF PEDIATRIC CHOLESTATIC LIVER DISEASES  
Provided herein are pediatric dosage forms for use in the treatment of a pediatric cholestatic liver disease by non-systemically administering to an individual in need thereof a therapeutically...
US20050192236 Crystaline clindamycin free base  
The antibiotic drug clindamycin is provided as a crystalline free base. Three polymorphic/pseudopolymorphic forms of crystalline clindamycin free base are disclosed. Also provided are...
US20100190686 NOVEL SECRETED PROTEINS OF ADIPOCYTES FOR DIAGNOSTIC PURPOSES  
The present invention relates to the discovery of polypeptide biomarkers excreted into the blood stream (serum or plasma) and/or urine from adipocytes and their use to determine the existence of...
US20110171187 DIETARY SUPPLEMENTS FOR PROMOTION OF GROWTH, REPAIR, AND MAINTENANCE OF BONE AND JOINTS  
The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises...
US20130338093 Bile Acid Recycling Inhibitors for Treatment of Pediatric Cholestatic Liver Diseases  
Provided herein are methods of treating or ameliorating a pediatric cholestatic liver disease by non-systemically administering to an individual in need thereof a therapeutically effective amount...
US20090023666 Modulators of Hypoxia Inducible Factor-1 and Related Uses  
The invention features compounds of formulas I or II: and pharmaceutically acceptable salts and prodrugs thereof, as well methods for modulating the effects of local and systemic hypoxic events...
US20140323412 BILE ACID RECYCLING INHIBITORS FOR TREATMENT OF HYPERCHOLEMIA AND CHOLESTATIC LIVER DISEASE  
Provided herein are methods of treating or ameliorating hypercholemia or a cholestatic liver disease by administering to an individual in need thereof a therapeutically effective amount of an...
US20130108573 Bile Acid Recycling Inhibitors for Treatment of Hypercholemia and Cholestatic Liver Disease  
Provided herein are methods of treating or ameliorating hypercholemia or a cholestatic liver disease by administering to an individual in need thereof a therapeutically effective amount of an...
US20110190233 ANIONIC CONJUGATES OF GLYCOSYLATED BACTERIAL METABOLITE  
The invention relates to anionic conjugates of glycosylated bacterial metabolites that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as...
US20080182805 O-GlcNAcase-specific inhibitor and substrate engineered by the extension of the N-Acetyl moiety  
An O-GlcNAcase-specific inhibitor and substrate are engineered by the extension of the N-Acetyl Moiety of O-(2-acet-amido-2-deoxy-D-glucopyranosylidene)amino-N-phenyl carbamate (PUGNAc). The...
US20080261864 Combination of nateglinide or repaglinide with at least one further antidiabetic compound  
The present invention relates to a combination of organic compounds which comprises at least two antidiabetic agents, preferably with different modes of action, in which the active ingredients are...
US20130045290 DERMAL REJUVENATION COMPOSITIONS AND METHODS  
The present invention relates, e.g., to a system for treating damaged skin, comprising a cosmeceutical formulation comprising about 1-10% of a mixture of perfluorocarbons (PFC's) of at least three...
US20110195025 ANIONIC OLIGOSACCHARIDE CONJUGATES  
The invention relates to anionic oligosaccharide conjugates that may be used to mimic the structure and/or activity of the anionic bioactive molecules known as glycosaminoglycans (GAGs).
US20080182806 USE OF ACETYLATED OR ESTERIFICATED AZACYTIDINE, DECITABINE, OR OTHER NUCLEOSIDE ANALOGS AS ORAL AGENTS FOR THE TREATMENT OF TUMORS OR OTHER DYSPLASTIC SYNDROMES SENSITIVE TO HYPOMETHYLATING AGENTS  
Compositions and methods for treating various diseases and disorders, such as for a myeldoysplastic syndrome are provided. The methods include administering to the subject a therapeutically...
US20140286899 INHIBITORS OF HEPATITIS C VIRUS  
A class of compounds that inhibit Hepatitis C Virus (HCV) is disclosed, along with compositions containing the compound, and methods of using the composition for treating individuals infected with...
US20090060867 PHOSPHADIAZINE HCV POLYMERASE INHIBITORS III AND VI  
Provided herein are phosphadiazine polymerase inhibitor, for example, of Formula III, pharmaceutical compositions comprising the compounds, and processes of preparation thereof. Also provided are...
US20090215710 CARBOHYDRATE BASED TOLL-LIKE RECEPTOR (TLR) ANTAGONISTS  
The invention provides carbohydrate based compounds, methods of preparation, and compositions useful for modulating signaling through Toll-like receptors. The methods involve contacting a...

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