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US20140154322 FOR INJECTABLE FORMULATIONS CONTAINING ASENAPINE AND METHOD OF TREATMENT USING SAME  
The present invention provides a formulation comprising asenapine hemipamoate suspended particles, which formulation can be administered via a Depot provided by an IM injection of the formulation,...
US20120237561 INJECTABLE FORMULATIONS CONTAINING ASENAPINE AND METHOD OF TREATMENT USING SAME  
The present invention provides a formulation comprising asenapine hemipamoate suspended particles, which formulation can be administered via a Depot provided by an IM injection of the formulation,...
US20110160642 PEGYLATED LIPOSOMAL FORMULATIONS FOR PHOTODYNAMIC TREATMENT OF INFLAMMATORY DISEASES  
A PDT treatment system designed to treat all types of human inflammatory disorders. A suitable drug delivery system is developed to target proliferating cells, at inflamed sites, populated with...
US20130210779 METHOD OF IDENTIFYING TRIPLE NEGATIVE BREAST CANCER  
The present invention provides means for identifying or classifying breast tumors based on the levels of nuclear cathepsin-L (CTSL) and nuclear p53 binding protein (53BP1), and methods of treating...
US20110009464 IMMUNE SYSTEM STIMULATION BY LIGHT THERAPY INDUCED APOPTOTIC CELL DEATH IN ABNORMAL TISSUE  
The efficacy of light activated therapy treatment is enhanced by stimulating the immune system of the patient substantially above the pre-therapy level. Abnormal tissue that is destroyed by the...
US20100331819 Drug Delivery System and Method of Treatment of Vascular Diseases Using Photodynamic Therapy  
This invention relates to photodynamic therapy (PDT), more specifically PDT for atherosclerotic plaque via delivering PDT-loaded nanoparticles such as liposomes, polymersomes, micelles and...
US20150119383 ACAMPROSATE FORMULATIONS, METHODS OF USING THE SAME, AND COMBINATIONS COMPRISING THE SAME  
Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other...
US20130245004 ACAMPROSATE FORMULATIONS, METHODS OF USING THE SAME, AND COMBINATIONS COMPRISING THE SAME  
Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other...
US20130143867 ACAMPROSATE FORMULATIONS, METHODS OF USING THE SAME, AND COMBINATIONS COMPRISING THE SAME  
Embodiments disclosed herein generally relate to acamprosate formulations, methods of use of the formulations, to methods of using the formulations in combination with at least one other...
US20120304318 CANCER DIAGNOSIS AND TREATMENT  
The invention concerns materials and methods relating to the use of OMD (osteomodulin) and\or PRELP (Proline/arginine-rich end leucine-rich repeat protein) expression, particularly...
US20110142948 Nanoparticle Carrier Systems based on Human Serum Albumin for Photodynamic Therapy  
Compositions, which are stable in storage, and a method of production of pharmaceutical based nanoparticulate formulations for photodynamic therapy comprising a hydrophobic photosensitizer, human...
US20120101427 NOVEL PHOTOSENSITIZER FORMULATIONS FOR ORAL ADMINISTRATION  
The present invention provides novel drug formulations for oral administration for diverse medical applications including anticancer, antimetastatic, antibacterial, antifungal, antiprotozoic,...
US20100310660 DRY POWDER MICROPARTICLES FOR PULMONARY DELIVERY  
The invention provides a dry powder microparticle for pulmonary delivery, which comprises at least one nanoparticle in the form of liposome or micelle wherein the nanopaparticle encapsulates one...
US20110257586 CALCIUMPHOSPHATE-BASED NANOPARTICLES AS CARRIER-SYSTEMS FOR PHOTODYNAMIC THERAPY  
The present invention provides pharmaceutical photosensitizer-loaded nanoparticle formulations and their methods of preparation for photodynamic therapy, comprising a hydrophobic or hydrophilic...
US20150190441 EXTRACT OF ASPLENIUM NIDUS L.  
An extract of Asplenium nidus L. includes pyropheophorbide a methyl ester (C34H36N4O3), pheophorbide a methyl ester (C35H36N4O5), 1-linleoyl-3-linolenoyl-glycerol (C39H66O5),...
US20140142157 EXTRACT OF ASPLENIUM NIDUS L.  
An extract of Asplenium nidus L. includes pyropheophorbide a methyl ester (C34H36N4O3), pheophorbide a methyl ester (C35H36N4O5), 1-linleoyl-3-linolenoyl-glycerol (C39H66O5),...
US20120015331 SCAFFOLD  
The present invention provides a polymeric scaffold containing an antibacterial photoactive drug and optionally comprising seeded cells such as stem cells. The invention also includes methods of...
US20140100188 PHENOTYPING TUMOR-INFILTRATING LEUKOCYTES  
The present disclosure relates to an immune signature of tumor infiltrating leukocytes. In particular, the disclosure provides methods and kits for determining the immune signature of tumor...
US20110123488 Method of Treatment for Cancers Associated with Elevated HER2 Levels  
Novel methods of treating proliferative disorders characterized by elevated Her-2, and the patient is then administered an effective amount of an HSP90 inhibitor.
US20120282297 METHOD FOR TREATING CONSTIPATION  
The invention relates to methods and compositions for the treatment of constipation. The method of the invention involves administration of a suppository containing chlorophyll, chlorophyllin...
US20130041307 APPLICATION OF BETA-FUNCTIONALIZED DIHYDROXY-CHLORINS FOR PDT  
The present invention provides methods to obtain biologically active compounds that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer,...
US20150202183 PATCH  
In a patch comprising a support layer and an adhesive agent layer, the adhesive agent layer comprises asenapine and/or a pharmaceutically acceptable salt thereof, isopropyl palmitate, and an...
US20110243854 Methods and systems for identifying modulators of longevity  
Methods of treating disorders such as neurofibromatosis-1 are provided, including methods in which catalytic antioxidants such as metalloporphyrins are administered. Methods of regulating...
US20130012754 MICROWAVE INDUCED PHOTODYNAMIC THERAPY  
A method of administering photodynamic therapy includes using a microwave frequency-sensitive light-emitting polymer as a light source to excite a administered photosensitizer to exert...
US20120232121 USE OF SARCOPLASMIC CA2+-ATPASE TYPE 2 PROTEIN FOR DIAGNOSING AND TREATING LEARNING OR MENTAL DISORDERS  
The present invention embraces methods for the diagnosis and treatment of learning or mental disorders, as well as the identification of agents useful in the treatment of such disorders based upon...
US20140228333 METHODS FOR INHIBITING MUSCLE ATROPHY  
In one aspect, the invention relates to methods for treating muscle atrophy by providing to an animal in need thereof an effective amount of a compound. The compound can modulate the expression...
US20140206667 METHODS AND COMPOSITIONS FOR TREATING SCHIZOPHRENIA  
The invention relates to methods and compositions for treating schizophrenia or bipolar disorder (in particular, mania) by using a combination of a synaptic vesicle protein 2A (SV2A) inhibitor and...
US20150231250 PATCH  
In a patch comprising a support layer and an adhesive agent layer, the adhesive agent layer comprises free asenapine, a maleic acid alkali salt, and a rubber-based adhesive agent.
US20140315863 TREATING BLADDER CANCER PATIENTS AND IDENTIFYING BLADDER CANCER PATIENTS RESPONSIVE TO TREATMENT  
This documents provided methods and materials involved in treating bladder cancer. This document also provides methods and materials involved in identifying bladder cancer patients likely or...
US20140314791 METHODS OF TREATING CANCER  
The present invention provides methods of treating cancer, particularly cancers that are null or have decreased expression or activity of the Lkb1 gene. Also included are methods of identifying...
US20110014204 Cancer Chemoprevention Strategy Based on Loss of Imprinting of IGF2  
The present invention relates to targets of loss of imprinting (LOI) affected IGF2 gene products in pre-malignant tissues, where methods of inhibiting those targets, including IGFR1, are disclosed...
US20150141478 SERIES OF DRUGS USING PHOTOFRIN TO CATALYZE DECOMPOSITION OF HYDROGEN PEROXIDE  
The present invention relates to a series of new drugs which refer to chemical series capable of catalyzing the decomposition of H2O2 to generate singlet oxygen (1O2). The drugs relate to...
US20150165026 SINGLET OXYGEN-LABILE LINKERS AND METHODS OF PRODUCTION AND USE THEREOF  
Activatable compositions that include at least one functional moiety and at least one cleavable linker directly or indirectly linked to the at least one functional moiety are disclosed. The at...
US20110206613 METHOD AND APPLICATION OF UNSYMMETRICALLY meso-SUBSTITUTED PORPHYRINS AND CHLORINS FOR PDT  
Biologically active compounds are provided that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and other hyperproliferative...
US20150140122 METHODS FOR DETECTING INACTIVATION OF THE HOMOLOGOUS RECOMBINATION PATHWAY (BRCA1/2) IN HUMAN TUMORS  
The invention relates to methods for detecting inactivation of the DNA Homologous Recombination pathway in a patient, and in particular for detecting BRCA1 inactivation.
US20110034854 PDT ASSISTED VISION CORRECTION AND SCAR PREVENTION  
A method and formulation are disclosed for improving the results of corneal refractive surgery, and generally reducing post-operative scarring and scarring arising from other traumas. In the...
US20150079111 MECHANISM, DIAGNOSTIC, AND TREATMENTS FOR COMPLICATIONS OF RENAL FAILURE  
Mechanisms for complications of renal failure and processes for treating the same are disclosed. They include contacting a biological fluid (e.g. blood) with a filter body, the filter body having...
US20130225545 PORPHYRIN TREATMENT OF NEURODEGENERATIVE DISEASES  
Compositions and methods of treating a neurodegenerative disorder are disclosed herein.
US20100130909 TREATMENT OF BARRETT'S ESOPHAGUS USING PHOTODYNAMIC THERAPY  
A method for treatment of Barrett's esophagus comprising the steps of: injecting HPPH in a physiologically compatible medium into a patient having Barrett's esophagus tissue to provide a dose...
US20130324582 METHODS AND COMPOSITIONS FOR REDUCING FUNGAL INFESTATION AND IMPROVING GRASS QUALITY  
Methods for reducing fungal infestation to a crop or plant by applying a composition including a dithiine-tetracarboximide compound to a crop or plant are described herein. Methods of reducing...
US20140105824 Hypoxia and hyaluronan and markers thereof for diagnosis and monitoring of diseases and conditions and related methods  
Provided herein are diagnostic methods for identifying subjects susceptible to treatment with a hypoxia-activated agent, and related methods. Also provided herein are methods of monitoring...
US20100137396 TREATMENT OF ESOPHAGEAL HIGH GRADE DYSPLASIA USING PHOTODYNAMIC THERAPY  
A method for treatment of esophageal high grade dysplasia comprising the steps of: injecting HPPH in a physiologically compatible medium into a patient having high grade dysplasia tissue to...
US20130323179 NANOCRYSTALS, COMPOSITIONS, AND METHODS THAT AID PARTICLE TRANSPORT IN MUCUS  
Nanocrystals, compositions, and methods that aid particle transport in mucus are provided. In some embodiments, the compositions and methods involve making mucus-penetrating particles (MPP)...
US20110262457 MODULATION OF THE IMMUNE RESPONSE  
Methods for increasing the generation of IL-17-producing T cells (TH17) in vivo and in vitro, and enriched populations of TH17 cells for the treatment of diseases benefiting from an induced or...
US20050244466 Photodynamic therapy in conjunction with intraocular implants  
A method for treating an ocular condition is provided. The method includes the steps of placing into an eye, a bioerodible implant comprising an anti-inflammatory component and a bioerodible...
US20150018301 LRRK-2-Mediated Neuronal Toxicity  
Leucine-rich repeat kinase-2 (LRRK2) mutations are a common cause of Parkinson's disease. Inhibitors of LRRK2 kinase that are protective in in vitro and in vivo models of LRRK2-induced...
US20110223255 IMPLANTABLE PRODUCTS COMPRISING NANOPARTICLES  
The present disclosure relates to nanoparticle-containing implantable and preferably biodegradable medical products and their use for the thermotherapeutic after-treatment after surgical removal...
US20120264802 PHOTOSENSITIZERS FOR TARGETED PHOTODYNAMIC THERAPY  
The present invention relates to photosensitizer compounds based on functionalized fullerenes useful in targeted photodynamic therapy (PDT), and methods of use thereof.
US20120020877 PROCESS AND INTRA-CERVICAL DEVICE FOR THE LOCAL RELEASE OF DRUGS IN THE LOCAL-REGIONAL TREATMENT OF CERVICAL CANCER  
An intrauterine device and more specifically an intracervical device (ICD) for the local release of drugs in the loco-regional treatment of tumours of the uterine cervix comprises an elongated...
US20140296209 COMPOUNDS AND METHODS FOR TREATMENT OF HYPERTENSION  
Hydrogenated pyrido[4,3-b]indoles, pyrido[3,4-b]indoles and azepino[4,5-b]indoles are described. The compounds may bind to and are adrenergic receptor α2B antagonists. The compounds may also bind...